-
1
-
-
0021022355
-
Immunoglobulin-gene rearrangements as unique clonal markers in human lymphoid neoplasms
-
Arnold A, Cossman J, Bakhshi A, Jaffe ES, Waldmann TA and Korsmeyer SJ (1983) Immunoglobulin-gene rearrangements as unique clonal markers in human lymphoid neoplasms. New England Journal of Medicine 309 1593-1599
-
(1983)
New England Journal of Medicine
, vol.309
, pp. 1593-1599
-
-
Arnold, A.1
Cossman, J.2
Bakhshi, A.3
Jaffe, E.S.4
Waldmann, T.A.5
Korsmeyer, S.J.6
-
2
-
-
0026331458
-
Maturation of the immune response in germinal centers
-
Berek C, Berger A and Apel M (1991) Maturation of the immune response in germinal centers. Cell 67 1121-1129
-
(1991)
Cell
, vol.67
, pp. 1121-1129
-
-
Berek, C.1
Berger, A.2
Apel, M.3
-
3
-
-
0025222785
-
Representative in vitro cDNA amplification from individual hemopoietic cells and colonies
-
Brady G, Barbara M and Iscove NN (1990) Representative in vitro cDNA amplification from individual hemopoietic cells and colonies. Methods in Molecular and Cellular Biology 2 1725
-
(1990)
Methods in Molecular and Cellular Biology
, vol.2
, pp. 1725
-
-
Brady, G.1
Barbara, M.2
Iscove, N.N.3
-
4
-
-
0029346879
-
Analysis of gene expression in a complex differentiation hierarchy by global amplification of cDNA from single cells
-
Brady G, Billia F, Knox J et al. (1995) Analysis of gene expression in a complex differentiation hierarchy by global amplification of cDNA from single cells. Current Biology 5 909-922
-
(1995)
Current Biology
, vol.5
, pp. 909-922
-
-
Brady, G.1
Billia, F.2
Knox, J.3
-
5
-
-
0029063311
-
Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction
-
Brezinschek HP, Brezinschek RI and Lipsky PE (1995) Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction. Journal of Immunology 155 190-202
-
(1995)
Journal of Immunology
, vol.155
, pp. 190-202
-
-
Brezinschek, H.P.1
Brezinschek, R.I.2
Lipsky, P.E.3
-
6
-
-
0028949125
-
Hodgkin and Reed-Sternberg cells do not carry T-cell receptor γ gene rearrangements: Evidence from single-cell polymerase chain reaction examination
-
Daus H, Trümper L, Roth J et al. (1995) Hodgkin and Reed-Sternberg cells do not carry T-cell receptor γ gene rearrangements: evidence from single-cell polymerase chain reaction examination. Blood 85 1590-1595
-
(1995)
Blood
, vol.85
, pp. 1590-1595
-
-
Daus, H.1
Trümper, L.2
Roth, J.3
-
7
-
-
0025778805
-
Detection of immunoglobulin gene rearrangement in B cell neoplasias by polymerase chain reaction gene amplification
-
Deane M and Norton JD (1991) Detection of immunoglobulin gene rearrangement in B cell neoplasias by polymerase chain reaction gene amplification. Leukemia and Lymphoma 5 922
-
(1991)
Leukemia and Lymphoma
, vol.5
, pp. 922
-
-
Deane, M.1
Norton, J.D.2
-
8
-
-
0028138515
-
Lymphocyte predominance Hodgkin's disease: Lineage and clonality determination using a single-cell assay
-
Delabie J, Tierens A, Wu G, Weisenburger DD and Chan WC (1994) Lymphocyte predominance Hodgkin's disease: lineage and clonality determination using a single-cell assay. Blood 84 3291-3298
-
(1994)
Blood
, vol.84
, pp. 3291-3298
-
-
Delabie, J.1
Tierens, A.2
Wu, G.3
Weisenburger, D.D.4
Chan, W.C.5
-
9
-
-
0027080048
-
Recent results on the biology of Hodgkin and Reed-Sternberg cells. I. Biopsy material
-
Drexler HG (1992) Recent results on the biology of Hodgkin and Reed-Sternberg cells. I. Biopsy material. Leukemia and Lymphoma 8 283-313
-
(1992)
Leukemia and Lymphoma
, vol.8
, pp. 283-313
-
-
Drexler, H.G.1
-
10
-
-
0029001936
-
Analysis of immunoglobulin gene rearrangements in single B cells
-
Ehlich A and Küppers R (1995) Analysis of immunoglobulin gene rearrangements in single B cells. Current Opinion in Immunology 7 281-284
-
(1995)
Current Opinion in Immunology
, vol.7
, pp. 281-284
-
-
Ehlich, A.1
Küppers, R.2
-
11
-
-
0028466384
-
Analysis of the B-cell progenitor compartment at the level of single cells
-
Ehlich A, Martin V, Müller W and Rajewsky K (1994) Analysis of the B-cell progenitor compartment at the level of single cells. Current Biology 4 573-583
-
(1994)
Current Biology
, vol.4
, pp. 573-583
-
-
Ehlich, A.1
Martin, V.2
Müller, W.3
Rajewsky, K.4
-
12
-
-
0002022760
-
Principles applications of in situ PCR
-
Gu J (1994) Principles and applications of in situ PCR. Cell Vision 1 8-19
-
(1994)
Cell Vision
, vol.1
, pp. 8-19
-
-
Gu, J.1
-
13
-
-
0027935346
-
The cellular biology of the Reed-Sternberg cell
-
Haluska FG, Brufsky AM and Canellos GP (1994) The cellular biology of the Reed-Sternberg cell. Blood 84 1005-1019
-
(1994)
Blood
, vol.84
, pp. 1005-1019
-
-
Haluska, F.G.1
Brufsky, A.M.2
Canellos, G.P.3
-
14
-
-
0029134785
-
Hodgkin's disease with monoclonal and polyclonal populations of Reed-Sternberg cells
-
Hummel M, Zieman K, Lammert H, Pileri S, Sabattini E and Stein H (1995) Hodgkin's disease with monoclonal and polyclonal populations of Reed-Sternberg cells. New England Journal of Medicine 333 901-906
-
(1995)
New England Journal of Medicine
, vol.333
, pp. 901-906
-
-
Hummel, M.1
Zieman, K.2
Lammert, H.3
Pileri, S.4
Sabattini, E.5
Stein, H.6
-
16
-
-
0028019076
-
The Reed-Sternberg cells of Hodgkin disease are clonal
-
Inghirami G, Macri L, Rosati S, Zhu BY, Yee HT and Knowles DM (1994) The Reed-Sternberg cells of Hodgkin disease are clonal. Proceedings of the National Academy of Sciences of the USA 91 9842-9846
-
(1994)
Proceedings of the National Academy of Sciences of the USA
, vol.91
, pp. 9842-9846
-
-
Inghirami, G.1
Macri, L.2
Rosati, S.3
Zhu, B.Y.4
Yee, H.T.5
Knowles, D.M.6
-
17
-
-
0026060620
-
Intraclonal generation of antibody mutants in germinal centres
-
Jacob J, Kelsoe G, Rajewsky K and Weiss U (1991) Intraclonal generation of antibody mutants in germinal centres. Nature 354 389-392
-
(1991)
Nature
, vol.354
, pp. 389-392
-
-
Jacob, J.1
Kelsoe, G.2
Rajewsky, K.3
Weiss, U.4
-
18
-
-
0030009310
-
Amplification of genes, single transcripts and cDNA libraries from one cell and direct sequence analysis of amplified products derived from one molecule
-
Jena PK, Liu AH, Smith DS and Wysocki LJ (1996) Amplification of genes, single transcripts and cDNA libraries from one cell and direct sequence analysis of amplified products derived from one molecule. Journal of Immunological Methodx 190 199-213
-
(1996)
Journal of Immunological Methodx
, vol.190
, pp. 199-213
-
-
Jena, P.K.1
Liu, A.H.2
Smith, D.S.3
Wysocki, L.J.4
-
19
-
-
0029983251
-
Molecular single cell analysis demonstrates the derivation of a peripheral blood-derived cell line (L1236) from the Hodgkin/Reed-Sternberg cells of a Hodgkin's lymphoma patient
-
Kanzler H, Hansmann ML, Kapp U et al. (1996a) Molecular single cell analysis demonstrates the derivation of a peripheral blood-derived cell line (L1236) from the Hodgkin/Reed-Sternberg cells of a Hodgkin's lymphoma patient. Blood 87 3429-3436
-
(1996)
Blood
, vol.87
, pp. 3429-3436
-
-
Kanzler, H.1
Hansmann, M.L.2
Kapp, U.3
-
20
-
-
0029952779
-
Hodgkin and Reed/Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells
-
Kanzler H, Küppers R, Hansmann ML and Rajewsky K (1996b) Hodgkin and Reed/Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells. Journal of Experimental Medicine 184 1495-1505
-
(1996)
Journal of Experimental Medicine
, vol.184
, pp. 1495-1505
-
-
Kanzler, H.1
Küppers, R.2
Hansmann, M.L.3
Rajewsky, K.4
-
22
-
-
0028033316
-
Variable region gene analysis of B cell subsets from a 4-year-old child: Somatically mutated memory B cells accumulate in the peripheral blood already at young age
-
Klein U, Küppers R and Rajewsky K (1994) Variable region gene analysis of B cell subsets from a 4-year-old child: somatically mutated memory B cells accumulate in the peripheral blood already at young age. Journal of Experimental Medicine. 180 1383-1393
-
(1994)
Journal of Experimental Medicine
, vol.180
, pp. 1383-1393
-
-
Klein, U.1
Küppers, R.2
Rajewsky, K.3
-
23
-
-
0029328401
-
Burkitt's lyinphoma is a malignancy of mature B cells expressing somatically mutated V region genes
-
Klein U, Klein C, Ehlin-Henriksson B, Rajewsky K and Küppers R (1995) Burkitt's lyinphoma is a malignancy of mature B cells expressing somatically mutated V region genes. Molecular Medicine 1 495-505
-
(1995)
Molecular Medicine
, vol.1
, pp. 495-505
-
-
Klein, U.1
Klein, C.2
Ehlin-Henriksson, B.3
Rajewsky, K.4
Küppers, R.5
-
24
-
-
1842405428
-
Evidence for a large compartment of IgM-expressing memory B cells in humans
-
Klein U, Küppers R and Rajewsky K Evidence for a large compartment of IgM-expressing memory B cells in humans. Blood 89 1288-1298
-
Blood
, vol.89
, pp. 1288-1298
-
-
Klein, U.1
Küppers, R.2
Rajewsky, K.3
-
25
-
-
0025873890
-
B cells of chronic lymphatic leukemia express V genes in unmutated form
-
Küppers R, Cause A and Rajewsky K (1991) B cells of chronic lymphatic leukemia express V genes in unmutated form. Leukemia Research 15 487-496
-
(1991)
Leukemia Research
, vol.15
, pp. 487-496
-
-
Küppers, R.1
Cause, A.2
Rajewsky, K.3
-
26
-
-
0027753103
-
Detection of clonal B cell populations in paraffin-embedded tissues by polymerase chain reaction
-
Küppers R, Zhao M, Rajewsky K and Hausmann ML (1993a) Detection of clonal B cell populations in paraffin-embedded tissues by polymerase chain reaction. American Journal of Pathology 143 230-239
-
(1993)
American Journal of Pathology
, vol.143
, pp. 230-239
-
-
Küppers, R.1
Zhao, M.2
Rajewsky, K.3
Hausmann, M.L.4
-
27
-
-
0027491651
-
Tracing B cell development in human germinal centers by molecular analysis of single cells picked from histological sections
-
Küppers R, Zhao M, Hansmann ML and Rajewsky K (1993b) Tracing B cell development in human germinal centers by molecular analysis of single cells picked from histological sections. EMBO Journal 12 4955-4967
-
(1993)
EMBO Journal
, vol.12
, pp. 4955-4967
-
-
Küppers, R.1
Zhao, M.2
Hansmann, M.L.3
Rajewsky, K.4
-
28
-
-
0028007479
-
Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development
-
Küppers R, Rajewsky K, Zhao M et al. (1994) Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of development. Proceedings of the National Academy of Sciences of the USA 91 10962-10966
-
(1994)
Proceedings of the National Academy of Sciences of the USA
, vol.91
, pp. 10962-10966
-
-
Küppers, R.1
Rajewsky, K.2
Zhao, M.3
-
29
-
-
0029126791
-
Detection of clonal λ light chain gene rearrangements in frozen and paraffin-embedded tissues by polymerase chain reaction
-
Küppers R, Willenbrock K, Rajewsky K and Hansmann ML (1995a) Detection of clonal λ light chain gene rearrangements in frozen and paraffin-embedded tissues by polymerase chain reaction. American Journal of Pathology 147 806-814
-
(1995)
American Journal of Pathology
, vol.147
, pp. 806-814
-
-
Küppers, R.1
Willenbrock, K.2
Rajewsky, K.3
Hansmann, M.L.4
-
31
-
-
0002806168
-
Micromanipulation and PCR analysis of single cells from tissue sections
-
Weir DM, Blackwell LA, Herzenberg LA and Herzenberg LA (eds), Blackwell Scientific, Oxford (in press)
-
Küppers R, Hansmann ML and Rajewsky K Micromanipulation and PCR analysis of single cells from tissue sections, In: Weir DM, Blackwell LA, Herzenberg LA and Herzenberg LA (eds). Handbook of Experimental Immunology, 5th ed., Blackwell Scientific, Oxford (in press)
-
Handbook of Experimental Immunology, 5th Ed.
-
-
Küppers, R.1
Hansmann, M.L.2
Rajewsky, K.3
-
32
-
-
0029813167
-
Molecular Ig gene analysis reveals that monocytoid B cell lymphoma is a malignancy of mature B cells carrying somatically mutated V region genes and suggests that rearrangement of the kappa-deleting element (resulting in deletion of the Ig kappa enhancers) abolishes somatic hypermntation in the human
-
Küppers R, Hajadi M, Plank L, Rajewsky K and Hansmann ML (1996a) Molecular Ig gene analysis reveals that monocytoid B cell lymphoma is a malignancy of mature B cells carrying somatically mutated V region genes and suggests that rearrangement of the kappa-deleting element (resulting in deletion of the Ig kappa enhancers) abolishes somatic hypermntation in the human. European Journal of Immunology 26 7791-7800
-
(1996)
European Journal of Immunology
, vol.26
, pp. 7791-7800
-
-
Küppers, R.1
Hajadi, M.2
Plank, L.3
Rajewsky, K.4
Hansmann, M.L.5
-
35
-
-
0024386188
-
Polymerase chain reaction using mixed primers: Cloning of human monoclonal antibody variable region genes from single hybridoma cells
-
Larrick JW, Danielsson L, Brenner CA et al. (1989) Polymerase chain reaction using mixed primers: cloning of human monoclonal antibody variable region genes from single hybridoma cells. Biotechnology 7 934-938
-
(1989)
Biotechnology
, vol.7
, pp. 934-938
-
-
Larrick, J.W.1
Danielsson, L.2
Brenner, C.A.3
-
36
-
-
0026687740
-
Sequencing heavy- and light-chain variable genes of single B-hybridoma cells by total enzymatic amplification
-
Liu AH, Creadon G and Wysocki LJ (1992) Sequencing heavy- and light-chain variable genes of single B-hybridoma cells by total enzymatic amplification. Proceedings of the National Academy of Sciences of the USA 89 7610-7614
-
(1992)
Proceedings of the National Academy of Sciences of the USA
, vol.89
, pp. 7610-7614
-
-
Liu, A.H.1
Creadon, G.2
Wysocki, L.J.3
-
37
-
-
0029886467
-
Surrogate light chain expression is required to establish immunoglobulin heavy chain allelic exclusion during early B cell development
-
Löffert D, Ehlich A, Müller W and Rajewsky K (1996) Surrogate light chain expression is required to establish immunoglobulin heavy chain allelic exclusion during early B cell development. Immunity 4 133-144
-
(1996)
Immunity
, vol.4
, pp. 133-144
-
-
Löffert, D.1
Ehlich, A.2
Müller, W.3
Rajewsky, K.4
-
38
-
-
0030020130
-
Single-cell PCR analysis of TCR repertoires selected by antigen in vivo: A high magnitude CD8 response is comprised of very few clones
-
Maryanski JL, Jongeneel CV, Bucher P, Casanova JL and Walker PR (1996) Single-cell PCR analysis of TCR repertoires selected by antigen in vivo: a high magnitude CD8 response is comprised of very few clones. Immunity 4 47-55
-
(1996)
Immunity
, vol.4
, pp. 47-55
-
-
Maryanski, J.L.1
Jongeneel, C.V.2
Bucher, P.3
Casanova, J.L.4
Walker, P.R.5
-
39
-
-
0028927653
-
Antigen-specific development of primary and memory T cells in vivo
-
McHeyzer-Williams MG and Davis MM (1995) Antigen-specific development of primary and memory T cells in vivo. Science 268 106-111
-
(1995)
Science
, vol.268
, pp. 106-111
-
-
McHeyzer-Williams, M.G.1
Davis, M.M.2
-
42
-
-
0022556211
-
Antigen-driven selection of virgin and memory B cells
-
MacLennan IGM and Gray D (1986) Antigen-driven selection of virgin and memory B cells. Immunological Reviews 91 61-85
-
(1986)
Immunological Reviews
, vol.91
, pp. 61-85
-
-
MacLennan, I.G.M.1
Gray, D.2
-
43
-
-
0028227203
-
Analysis of somatic mutation in five B cell subsets of human tonsil
-
Pascual V, Liu YL, Magalski A, De Bouteiller O, Banchereau J and Capra JD (1994) Analysis of somatic mutation in five B cell subsets of human tonsil. Journal of Experimental Medicine 180 329-339
-
(1994)
Journal of Experimental Medicine
, vol.180
, pp. 329-339
-
-
Pascual, V.1
Liu, Y.L.2
Magalski, A.3
De Bouteiller, O.4
Banchereau, J.5
Capra, J.D.6
-
44
-
-
0024356882
-
Ig V gene expression in small lymphocytic lymphoma with little or no somatic mutation
-
Pratt LF, Rassenti L, Larrick J, Bobbins B, Banks PM and Kipps TJ (1989) Ig V gene expression in small lymphocytic lymphoma with little or no somatic mutation. Journal of Immunology 143 699-705
-
(1989)
Journal of Immunology
, vol.143
, pp. 699-705
-
-
Pratt, L.F.1
Rassenti, L.2
Larrick, J.3
Bobbins, B.4
Banks, P.M.5
Kipps, T.J.6
-
45
-
-
0030006070
-
Clonal selection and learning in the antibody system
-
Rajewsky K (1996) Clonal selection and learning in the antibody system. Nature 381 751-758
-
(1996)
Nature
, vol.381
, pp. 751-758
-
-
Rajewsky, K.1
-
46
-
-
0027462916
-
Lack of extensive mutations in the VH5 genes used in common B cell chronic lymphocytic leukemia
-
Rassenti LZ and Kipps TJ (1993) Lack of extensive mutations in the VH5 genes used in common B cell chronic lymphocytic leukemia. Journal of Experimental Medicine 177 1039-1046
-
(1993)
Journal of Experimental Medicine
, vol.177
, pp. 1039-1046
-
-
Rassenti, L.Z.1
Kipps, T.J.2
-
47
-
-
0028295279
-
Detection of Epstein-Barr virus DNA in Hodgkin- And Reed-Sternberg-cells by single cell PCR
-
Roth J, Daus H, Cause A, Trümper L and Pfreundschuh M (1994a) Detection of Epstein-Barr virus DNA in Hodgkin- and Reed-Sternberg-cells by single cell PCR. Leukemia and Lymphoma 13 137-142
-
(1994)
Leukemia and Lymphoma
, vol.13
, pp. 137-142
-
-
Roth, J.1
Daus, H.2
Cause, A.3
Trümper, L.4
Pfreundschuh, M.5
-
48
-
-
0028242427
-
Detection of immunoglobulin heavy-chain gene rearrangement at the single-cell level in malignant lymphomas: No rearrangement is found in Hodgkin and Reed-Sternberg cells
-
Roth J, Daus H, Trümper L, Gause A, Salamon-Looijen M and Pfreundschuh M (1994b) Detection of immunoglobulin heavy-chain gene rearrangement at the single-cell level in malignant lymphomas: no rearrangement is found in Hodgkin and Reed-Sternberg cells. International Journal of Cancer 57 799-804
-
(1994)
International Journal of Cancer
, vol.57
, pp. 799-804
-
-
Roth, J.1
Daus, H.2
Trümper, L.3
Gause, A.4
Salamon-Looijen, M.5
Pfreundschuh, M.6
-
49
-
-
0029072869
-
The human germinal center cells, follicular dendritic cells and germinal centre T cells produce B cell-stimulating cytokines
-
Toellner KM, Scheel-Toellner D, Sprenger R et al. (1995) The human germinal center cells, follicular dendritic cells and germinal centre T cells produce B cell-stimulating cytokines. Cytokine 7 344-354
-
(1995)
Cytokine
, vol.7
, pp. 344-354
-
-
Toellner, K.M.1
Scheel-Toellner, D.2
Sprenger, R.3
-
51
-
-
0027178303
-
Single-cell analysis of Hodgkin and Reed-Sternberg cells: Molecular heterogeneity of gene expression and p53 mutations
-
Trümper L, Brady G, Bagg A et al. (1993) Single-cell analysis of Hodgkin and Reed-Sternberg cells: molecular heterogeneity of gene expression and p53 mutations. Blood 81 3097-3115
-
(1993)
Blood
, vol.81
, pp. 3097-3115
-
-
Trümper, L.1
Brady, G.2
Bagg, A.3
-
52
-
-
0029914964
-
N-ras genes are not mutated in Hodgkin and Reed-Sternberg cells: Results from single cell polymerase chain reaction examinations
-
Trümper L, Pfreundschuh M, Jacobs G et al. (1996) N-ras genes are not mutated in Hodgkin and Reed-Sternberg cells: results from single cell polymerase chain reaction examinations. Leukemia 10 727-730
-
(1996)
Leukemia
, vol.10
, pp. 727-730
-
-
Trümper, L.1
Pfreundschuh, M.2
Jacobs, G.3
-
54
-
-
15844383634
-
Peripheral blood mononuclear cells of a patient with advanced Hodgkin's lymphoma give rise to permanently growing Hodgkin-Reed Sternberg cells
-
Wolf J, Kapp U, Bohlen H et al. (1996) Peripheral blood mononuclear cells of a patient with advanced Hodgkin's lymphoma give rise to permanently growing Hodgkin-Reed Sternberg cells. Blood 87 3418-3428
-
(1996)
Blood
, vol.87
, pp. 3418-3428
-
-
Wolf, J.1
Kapp, U.2
Bohlen, H.3
|