Association of interferon-gamma +874(T/A) single nucleotide polymorphism with the rate of tryptophan catabolism in healthy individuals

Scandinavian Journal of Immunology

Volumn 61, Issue 4, 2005, Pages 387-390

  Raitala, A ^a   Pertovaara, M ^b   Karjalainen, J ^c   Oja, S S ^a,c   Hurme, M ^a,b  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b TAMPERE UNIVERSITY HOSPITAL   (Finland)

^c Department of Respiratory Medicine ^*  (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INDOLEAMINE 2,3 DIOXYGENASE; KYNURENINE; TRYPTOPHAN;

ADULT; ARTICLE; BLOOD DONOR; CATABOLISM; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; ENZYME REGULATION; FEMALE; GENETIC POLYMORPHISM; GENETIC REGULATION; GENOTYPE; HUMAN; HUMAN EXPERIMENT; IMMUNE RESPONSE; MALE; NORMAL HUMAN; PATHOGENESIS; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TRYPTOPHAN METABOLISM;

ADULT; DIOXYGENASES; DNA; FEMALE; HUMANS; INTERFERON TYPE II; KYNURAMINE; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; TRYPTOPHAN;

EID: 18344389175     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-3083.2005.01586.x     Document Type: Article

References (18)

1. Mellor AL, Munn DH. Tryptophan catabolism and T-cell tolerance: immunosuppression by starvation? Immunol Today 1999;10:469-73.
2. Mellor AL, Munn DH. Ido expression by dendritic cells: tolerance and tryptophan catabolism. Nat Rev Immunol 2004;4:762-74.
3. Mellor AL, Munn DH. Tryptophan catabolism and regulation of adaptive immunity. J Immunol 2003;170:5809-13.
4. Uyttenhove C, Pilotte L, Théate I et al. Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase. Nat Med 2003;9:1269-74.
5. Pravica V, Asderakis A, Perrey C, Hajeer A, Sinnott PJ, Hutchinson IV. In vitro production of IFN-γ correlates with CA repeat polymorphism in the human IFN-γ gene. Eur J Immunogenet 1999;26:1-3.
6. Pravica V, Perrey C, Stevens A, Lee J-H, Hutchinson IV. A single nucleotide polymorphism in the first intron of the human IFN-γ gene: absolute correlation with a polymorphic CA microsatellite marker of high IFN-γ production. Hum Immunol 2000;61:863-66.
7. Rossouw M, Nel HJ, Cooke GS, van Helden PD, Hoal EG. Association between tuberculosis and a polymorphic NF-κB binding site in the interferon γ gene. Lancet 2003;361:1871-72.
8. Widner B, Werner R, Schennach H, Wachter H, Fuchs D. Simultaneous measurement of serum tryptophan and kynurenine by HPLC. Clin Chem 1997;43:2424-26.
9. Laich A, Neurauter G, Widner B, Fuchs D. More rapid method for simultaneous measurement of tryptophan and kynurenine by HPLC. Clin Chem 2002;48:579-81.
10. Bream JH, Carrington M, O'Toole S et al. Polymorphisms of the human IFNG gene noncoding regions. Immunogenetics 2000;51:50-58.
11. Awad M, Pravica V, Perrey C et al. CA repeat allele polymorphism in the first intron of human interferon-γ gene is associated with lung allograft fibrosis. Hum Immunol 1999;60:343-46.
12. Asderakis A, Sankaran D, Dyer P et al. Association of polymorphisms in the human interferon-gamma and interleukin-10 gene with acute and chronic kidney transplant outcome: the cytokine effect on transplantation. Transplantation 2001;71 (5):674-77.
13. Dufour C, Capasso M, Svahn J et al. Homozygosis for (12) CA repeats in the first intron of the human IFN-gamma gene is significantly associated with the risk of aplastic anaemia in Caucasian population. Br J Haematol 2004;126 (5):682-85.
14. López-Maderuelo D, Arnalich F, Serantes R et al. Interferon-γ and interleukin-10 gene polymorphisms in pulmonary tuberculosis. Am J Respir Crit Care Med 2003;167:970-75.
15. Lio D, Marino V, Serauto A et al. Genotype frequencies of the +874T→A single nucleotide polymorphism in the first intron of the interferon-γ gene in a sample of Sicilian patients affected by tuberculosis. Eur J Immunogenet 2002;29:371-74.
16. Kerr JR, McCoy M, Burke B, Mattey DL, Pravica V, Hutchinson IV. Cytokine gene polymorphisms associated with symptomatic parvovirus B19 infection. J Clin Pathol 2003;56:725-27.
17. Daher S, Schulzhenko N, Morgun A et al. Associations between cytokine gene polymorphisms and recurrent pregnancy loss. J Reprod Immunol 2003;58:69-77.
18. Lio D, Scola L, Crivello A et al. Allele frequencies of +874T→A single nucleotide polymorphism at the first intron of interferon-γ gene in a group of Italian centenarians. Exp Gerontol 2002;37:315-19.