Sperm count and chromatin structure in men exposed to inorganic lead: Lowest adverse effect levels

Occupational and Environmental Medicine

Volumn 59, Issue 4, 2002, Pages 234-242

  Bonde, J P ^a   Joffe, M ^b   Apostoli, P ^c   Dale, A ^b   Kiss, P ^d   Spano, M ^e   Caruso, F ^e   Giwercman, A ^f   Bisanti, L ^g   Porru, S ^c   Vanhoorne, M ^d   Comhaire, F ^d   Zschiesche, W ^h  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^c UNIVERSITY OF BRESCIA   (Italy)

^d GHENT UNIVERSITY   (Belgium)

^e ENEA C R CASACCIA   (Italy)

^f University of Copenhagen   (Denmark)

^g Local Health Authority   (Italy)

^h UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LEAD;

ADULT; ARTICLE; CHROMATIN STRUCTURE; EUROPE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LEAD BLOOD LEVEL; LEAD POISONING; LINEAR REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; OCCUPATIONAL EXPOSURE; PRIORITY JOURNAL; PROTEIN DEGRADATION; SEMEN ANALYSIS; SPERMATOGENESIS; SPERMATOZOON; SPERMATOZOON COUNT; STATISTICAL ANALYSIS;

ADULT; ANALYSIS OF VARIANCE; CHROMATIN; CROSS-SECTIONAL STUDIES; FLOW CYTOMETRY; HUMANS; LEAD; MALE; MIDDLE AGED; OCCUPATIONAL EXPOSURE; SEMEN; SPERM COUNT;

EID: 18344365004     PISSN: 13510711     EISSN: None     Source Type: Journal    
DOI: 10.1136/oem.59.4.234     Document Type: Article

References (34)

1. Semen quality of men employed at a lead smelter
2. Sperm count suppression without endocrine dysfunction in lead exposed men
3. Reproductive ability of workmen occupationally exposed to lead
4. Study of sperm characteristics in persons occupationally exposed to lead
5. Semen quality and reproductive endocrine function in relation to biomarkers of lead, cadmium, zinc, and copper in men
6. Improvement in semen quality associated with decreasing occupational lead exposure
7. Semen quality and fertility of men employed in a South African lead acid battery plant
8. Male reproductive toxicity of lead in animals and humans
9. Male reproductive effects of lead, including species extrapolation for the rabbit model
10. Age and secular trends in bone lead levels in middle-aged and elderly men: 3 Year longitudinal follow up in the normative aging study
11. Blood lead levels in children in south central Los Angeles
12. Secular trend in blood lead levels in a cohort of Mexico City children
13. Maternal blood lead level during pregnancy in south central Los Angeles
14. Blood lead level, by year and season, among poor pregnant women
15. The applicability of the flow cytometric sperm chromatin structure assay in epidemiological studies. Asclepios
16. Sperm chromatin structure is altered in cynomolgus monkeys with environmentally relevant blood lead levels
17. Relation between semen quality and fertility: A population-based study of 430 first-pregnancy planners
18. Sperm chromatin damage impairs human fertility
19. Objectives, designs and populations of the European Asclepios study on occupational hazards to male reproductive capability
20. Susceptibility of human sperm to in situ DNA denaturation is strongly correlated with DNA strand breaks identified by single cell electrophoresis
21. Individuality of DNA denaturation patterns in human sperm as measured by the sperm chromatin structure assay
22. Quality assurance of semen analysis in multicenter studies. Asclepios
23. Multiple determination of elements in human seminal plasma and spermatozoa
24. A European concerned action: Maternal alcohol consumption and its relation to the outcome of pregnancy and child development at 18 months
25. Selection bias in occupational sperm studies
26. Identifying environmental risk to male reproductive function by occupational sperm studies: Logistics and design options
27. Within-subject variability of human semen in regard to sperm count, volume and number of spermatozoa and length of abstinence
28. Critical aspects of male fertility in the assessment of exposure to lead
29. The reproductive toxicity and carcinogenicity of lead: A critical review
30. Lead interaction with human protamin (HP2) as a mechanism of male reproductive toxicity
31. Interaction of blood lead and delta-aminolevulinic acid dehydratase genotype on markers of heme synthesis and sperm production in lead smelter workers