Lysosomal localization of murine CD1d mediated by AP-3 is necessary for NK T cell development

Journal of Immunology

Volumn 171, Issue 8, 2003, Pages 4149-4155

  Cernadas, Manuela ^a   Sugita, Masahiko ^b   Van der Wel, Nicole ^c   Cao, Xiaochun ^d   Gumperz, Jenny E ^a   Maltsev, Sergei ^e   Besra, Gurdyal S ^e   Behar, Samuel M ^a   Peters, Peter J ^c   Brenner, Michael B ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b NIPPON MEDICAL SCHOOL   (Japan)

^c NETHERLANDS CANCER INSTITUTE   (Netherlands)

^d MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^e UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ANTIGEN; CD1 ANTIGEN; CD1B ANTIGEN; CD1C ANTIGEN; CD1D ANTIGEN; GLYCOLIPID; LIPID; MEMBRANE PROTEIN; T LYMPHOCYTE RECEPTOR; T6 ANTIGEN; TETRAMER; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 3; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; B LYMPHOCYTE; CELL MATURATION; CELL SURFACE; CONTROLLED STUDY; DENDRITIC CELL; HELA CELL; HOST RESISTANCE; HUMAN; HUMAN CELL; LYSOSOME; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; SPLEEN CELL; THYMOCYTE;

EID: 0141958157     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.171.8.4149     Document Type: Article

References (52)

1. Calabi, F., and C. Milstein. 2000. The molecular biology of CD1. Semin. Immunol. 12:503.
2. + T cells. Nature 372:691.
3. Beckman. E. M., A. Melian, S. M. Behar, P. A. Sieling, D. Chatterjee, S. T. Furlong, R. Matsumoto, J. P. Rosat, R. L. Modlin, and S. A. Porcelli. 1996. CD1c restricts responses of mycobacteria-specific T cells: evidence for antigen presentation by a second member of the human CD1 family. J. Immunol. 157:2795.
4. Sieling, P. A., D. Chatterjee, S. A. Porcelli, T. I. Prigozy, R. J. Mazzaccaro, T. Soriano, B. R. Bloom, M. B. Brenner, M. Kronenberg, P. J. Brennan, et al. 1995. CD1-restricted T cell recognition of microbial lipoglycan antigens. Science 269:227.
5. Chiu, Y. H., J. Jayawardena, A. Weiss, D. Lee, S. H. Park, A. Dautry-Varsat, and A. Bendelac. 1999. Distinct subsets of CD1d-restricted T cells recognize self-antigens loaded in different cellular compartments. J. Exp. Med. 189:103.
6. Gumperz, J. E., C. Roy, A. Makowska, D. Lum, M. Sugita, T. Podrebarac, Y. Koezuka, S. A. Porcelli, S. Cardell, M. B. Brenner, et al. 2000. Murine CD1d-restricted T cell recognition of cellular lipids. Immunity 12:211.
7. Kawano, T., J. Cui, Y. Koezuka, I. Toura, Y. Kaneko, K. Motoki, H. Ueno, R. Nakagawa, H. Sato, E. Kondo, et al. 1997. CD1d-restricted and TCR-mediated activation of vα14 NKT cells by glycosylceramides. Science 278:1626.
8. Spada, F. M., Y. Koezuka, and S. A. Porcelli. 1998. CD1d-restricted recognition of synthetic glycolipid antigens by human natural killer T cells. J. Exp. Med. 188:1529.
9. Matsuda, J. L., O. V. Naidenko, L. Gapin, T. Nakayama, M. Taniguchi, C. R. Wang, Y. Koezuka, and M. Kronenberg. 2000. Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers. J. Exp. Med. 192:741.
10. + T cell subsets: a subset (Thy0) that secretes diverse cytokines and overexpresses the Vβ8 T cell receptor gene family. J. Exp. Med. 176:269.
11. - thymocytes with specific lymphokine secretion. Eur. J. Immunol. 23:307.
12. + T cells in a TH2 response and in immunoglobulin E production. Science 270:1845.
13. Eberl, G., and H. R. MacDonald. 2000. Selective induction of NK cell proliferation and cytotoxicity by activated NKT cells. Eur. J. Immunol. 30:985.
14. Briken, V., R. M. Jackman, S. Dasgupta, S. Hoening, and S. A. Porcelli. 2002. Intracellular trafficking pathway of newly synthesized CD1b molecules. EMBO J. 21:825.
15. Dell'Angelica, E. C., V. Shotelersuk, R. C. Aguilar, W. A. Gahl, and J. S. Bonifacino. 1999. Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the β3A subunit of the AP-3 adaptor. Mol. Cell. 3:11.
16. Yang, W., C. Li, D. M. Ward, J. Kaplan, and S. L. Mansour. 2000. Defective organellar membrane protein trafficking in Ap3b1-deficient cells. J. Cell Sci. 113:4077.
17. Sugita, M., R. M. Jackman, E. van Donselaar, S. M. Behar, R. A. Rogers, P. J. Peters, M. B. Brenner, and S. A. Porcelli. 1996. Cytoplasmic tail-dependent localization of CD1b antigen-presenting molecules to MIICs. Science 273:349.
18. Sugita, M., X. Cao, G. F. Watts, R. A. Rogers, J. S. Bonifacino, and M. B. Brenner. 2002. Failure of trafficking and antigen presentation by CD1 in AP-3-deficient cells. Immunity 16:697.
19. Briken, V., R. M. Jackman, G. F. Watts, R. A. Rogers, and S. A. Porcelli. 2000. Human CD1b and CD1c isoforms survey different intracellular compartments for the presentation of microbial lipid antigens. J. Exp. Med. 192:281.
20. Schaible, U. E., K. Hagens, K. Fischer, H. L. Collins, and S. H. Kaufmann. 2000. Intersection of group 1 CD1 molecules and mycobacteria in different intracellular compartments of dendritic cells. J. Immunol. 164:4843.
21. Sugita, M., N. van Der Wel, R. A. Rogers, P. J. Peters, and M. B. Brenner. 2000. CD1c molecules broadly survey the endocytic system. Proc. Natl. Acad. Sci. USA 97:8445.
22. Sugita, M., E. P. Grant, E. van Donselaar, V. W. Hsu, R. A. Rogers, P. J. Peters, and M. B. Brenner. 1999. Separate pathways for antigen presentation by CD1 molecules. Immunity 11:743.
23. Sugita, M., P. J. Peters, and M. B. Brenner. 2000. Pathways for lipid antigen presentation by CD1 molecules: nowhere for intracellular pathogens to hide. Traffic 1:295.
24. Jackman, R. M., S. Stenger, A. Lee, D. B. Moody, R. A. Rogers, K. R. Niazi, M. Sugita, R. L. Modlin, P. J. Peters, and S. A. Porcelli. 1998. The tyrosine-containing cytoplasmic tail of CD1b is essential for its efficient presentation of bacterial lipid antigens. Immunity 8:341.
25. Chiu, Y. H., S. H. Park, K. Benlagha, C. Forestier, J. Jayawardena-Wolf, P. B. Savage, L. Teyton, and A. Bendelac. 2002. Multiple defects in antigen presentation and T cell development by mice expressing cytoplasmic tail-truncated CD1d. Nat. Immunol. 3:55.
26. Feng, L., A. B. Seymour, S. Jiang, A. To, A. A. Peden, E. K. Novak, L. Zhen, M. E. Rusiniak, E. M. Eicher, M. S. Robinson, et al. 1999. The β3A subunit gene (Ap3b1) of the AP-3 adaptor complex is altered in the mouse hypopigmentation mutant pearl, a model for Hermansky-Pudlak syndrome and night blindness. Hum. Mol. Genet. 8:323.
27. Zhen, L., S. Jiang, L. Feng, N. A. Bright, A. A. Peden, A. B. Seymour, E. K. Novak, R. Elliott, M. B. Gorin, M. S. Robinson, et al. 1999. Abnormal expression and subcellular distribution of subunit proteins of the AP-3 adaptor complex lead to platelet storage pool deficiency in the pearl mouse. Blood 94:146.
28. Peden, A. A., R. E. Rudge, W. W. Lui, and M. S. Robinson. 2002. Assembly and function of AP-3 complexes in cells expressing mutant subunits. J. Cell Biol. 156:327.
29. Villadangos, J. A., M. Cardoso, R. J. Steptoe, D. van Berkel, J. Pooley, F. R. Carbone, and K. Shortman. 2001. MHC class 11 expression is regulated in dendritic cells independently of invariant chain degradation. Immunity 14:739.
30. Gumperz, J. E., S. Miyake, T. Yamamura, and M. B. Brenner. 2002. Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining. J. Exp. Med. 195:625.
31. Higa, T., T. Natozi, Y. Koezuka, and K. Motok. 1988. U.S. Patent 5,780,441.
32. Peters, P. J., V. W. Hsu, C. E. Ooi, D. Finazzi, S. B. Teal, V. Oorschot, J. G. Donaldson, and R. D. Klausner. 1995. Overexpression of wild-type and mutant ARF1 and ARF6: distinct perturbations of nonoverlapping membrane compartments. J. Cell Biol. 128:1003.
33. Griffiths, G. M., and S. Isaaz. 1993. Granzymes A and B are targeted to the lytic granules of lymphocytes by the mannose-6-phosphate receptor. J. Cell Biol. 120:885.
34. Mayhew, T. M., J. M. Lucocq, and G. Griffiths. 2002. Relative labelling index: a novel stereological approach to test for non-random immunogold labelling of organelles and membranes on transmission electron microscopy thin sections. J. Microsc. 205:153.
35. Sugita, M., and M. B. Brenner. 1995. Association of the invariant chain with major histocompatibility complex class I molecules directs trafficking to endocytic compartments. J. Biol. Chem. 270:1443.
36. Carlsson, S. R., J. Roth, F. Piller, and M. Fukuda. 1988. Isolation and characterization of human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2: major sialoglycoproteins carrying polylactosaminoglycan. J. Biol. Chem. 263:18911.
37. + T cell development and early IL-4 production in CDI-deficient mice. Immunity 6:459.
38. Mendiratta, S. K., W. D. Martin, S. Hong, A. Boesteanu, S. Joyce, and L. Van Kaer. 1997. CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4. Immunity 6:469.
39. Boehm, M., and J. S. Bonifacino. 2001. Adaptins: the final recount. Mol. Biol. Cell. 12:2907.
40. Hiltbold, E. M., and P. A. Roche. 2002. Trafficking of MHC class II molecules in the late secretory pathway. Curr. Opin. Immunol. 14:30.
41. Owen, D. J., Y. Vallis, M. E. Noble, J. B. Hunter, T. R. Dafforn, P. R. Evans, and H. T. McMahon. 1999. A structural explanation for the binding of multiple ligands by the α-adaptin appendage domain. Cell 97:805.
42. Ohno, H., M. C. Fournier, G. Poy, and J. S. Bonifacino. 1996. Structural determinants of interaction of tyrosine-based sorting signals with the adaptor medium chains. J. Biol. Chem. 271:29009.
43. Stephens, D. J., and G. Banting. 1998. Specificity of interaction between adaptor-complex medium chains and the tyrosine-based sorting motifs of TGN38 and lgp120. Biochem. J. 335:567.
44. Jayawardena-Wolf, J., K. Benlagha, Y. H. Chiu, R. Mehr, and A. Bendelac. 2001. CD1d endosomal trafficking is independently regulated by an intrinsic CD1d-encoded tyrosine motif and by the invariant chain. Immunity 15:897.
45. Kang, S. J., and P. Cresswell. 2002. Regulation of intracellular trafficking of human CD1d by association with MHC class II molecules. EMBO J. 21:1650.
46. + T cell selection and maturation by cathepsin S. Immunity 15:909.
47. Sevilla, L. M., S. S. Richter, and J. Miller. 2001. Intracellular transport of MHC class II and associated invariant chain in antigen presenting cells from AP-3-deficient mocha mice. Cell. Immunol. 210:143.
48. Caplan, S., E. C. Dell'Angelica, W. A. Gahl, and J. S. Bonifacino. 2000. Trafficking of major histocompatibility complex class II molecules in human B-lymphoblasts deficient in the AP-3 adaptor complex. Immunol. Lett. 72:113.
49. Park, S. H., J. H. Roark, and A. Bendelac. 1998. Tissue-specific recognition of mouse CD1 molecules. J. Immunol. 160:3128.
50. Chen, Y. H., B. Wang, T. Chun, L. Zhao, S. Cardell, S. M. Behar, M. B. Brenner. and C. R. Wang. 1999. Expression of CD1d2 on thymocytes is not sufficient for the development of NK T cells in CD1d1-deficient mice. J. Immunol. 162:4560.
51. Cao, X., M. Sugita, N. Van Der Wel, J. Lai, R. A. Rogers, P. J. Peters, and M. B. Brenner. 2002. CD1 molecules efficiently present antigen in immature dendritic cells and traffic independently of MHC class II during dendritic cell maturation. J. Immunol. 169:4770.
52. van der Wel, N., M. Sugita, D. M. Fluitsma, X. Cao, G. Schreibelt, M. B. Brenner, and P. J. Peters. 2003. CD1 and major histocompatibility complex 11 molecules follow a different course during dendritic cell maturation. Mol. Biol. Cell 14:3378.