Reduced expression of insulin-like growth factor binding protein-3 and its promoter hypermethylation in human hepatocellular carcinoma

Cancer Letters

Volumn 176, Issue 2, 2002, Pages 149-158

  Hanafusa, Tadashi ^a   Yumoto, Yasuhiro ^a   Nouso, Kazuhiro ^a   Nakatsukasa, Harushige ^a   Onishi, Toru ^a   Fujikawa, Tatsuya ^a   Taniyama, Mayumi ^a   Nakamura, Shinichiro ^a   Uemura, Masayuki ^a   Takuma, Yoshitaka ^a   Yumoto, Eiichiro ^a   Higashi, Toshihiro ^a   Tsuji, Takao ^a  

^a OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

cDNA microarray; Hepatocellular carcinoma; Hypermethylation; Insulin like growth factor binding protein 3; Mannose 6 phosphate insulin like growth factor 2 receptor

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; SOMATOMEDIN BINDING PROTEIN 3;

ARTICLE; CELL LINE; CONTROLLED STUDY; DEMETHYLATION; DNA EXTRACTION; GROWTH INHIBITION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; METHYLATION; MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RNA EXTRACTION; TUMOR SUPPRESSOR GENE;

ANTIMETABOLITES, ANTINEOPLASTIC; AZACITIDINE; BASE SEQUENCE; BLOTTING, NORTHERN; CARCINOMA, HEPATOCELLULAR; CHROMOSOMES, HUMAN, PAIR 7; DNA METHYLATION; DNA, COMPLEMENTARY; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; LIVER NEOPLASMS; LOSS OF HETEROZYGOSITY; MANNOSEPHOSPHATES; MOLECULAR SEQUENCE DATA; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROMOTER REGIONS (GENETICS); RECEPTOR, IGF TYPE 2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; TUMOR CELLS, CULTURED;

EID: 18244401685     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(01)00736-4     Document Type: Article

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