Structural and biologic characterization of pegylated recombinant IFN-β2b

Journal of Interferon and Cytokine Research

Volumn 21, Issue 12, 2001, Pages 1103-1115

  Grace, Michael ^a   Youngster, Stephen ^a   Gitlin, Gerry ^a   Sydor, Wasyl ^a   Lei, Xie ^a   Westreich, Louis ^a   Jacobs, Sheila ^a   Brassard, Diana ^a   Bausch, James ^a   Bordens, Ronald ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2',5' OLIGOADENYLATE SYNTHETASE; ALPHA INTERFERON; HISTIDINE; MACROGOL DERIVATIVE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PEG 12000; PROTEIN KINASE; RECOMBINANT ALPHA2B INTERFERON;

ANTIGEN RECOGNITION; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CELL LEVEL; CIRCULAR DICHROISM; CYTOPATHOGENIC EFFECT; DOSE RESPONSE; DRUG ACTIVITY; DRUG POTENCY; GEL PERMEATION CHROMATOGRAPHY; GENE INDUCTION; IMMUNE RESPONSE; INTRON; ISOMER; LYMPHOKINE ACTIVATED KILLER CELL; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NATURAL KILLER CELL; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; ANTIVIRAL AGENTS; CELLS, CULTURED; CHROMATOGRAPHY, GEL; CIRCULAR DICHROISM; CYTOTOXICITY TESTS, IMMUNOLOGIC; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INTERFERON ALFA-2A; ISOMERISM; MODELS, MOLECULAR; POLYETHYLENE GLYCOLS; RNA, MESSENGER; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 18244377180     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/107999001317205240     Document Type: Article

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