Growth hormone and sex steroid effects on bone metabolism and bone mineral density in healthy aged women and men

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 57, Issue 1, 2002, Pages M12-M18

  Christmas, Colleen ^a   O'Connor, Kieran G ^a   Harman, S Mitchell ^b   Tobin, Jordan D ^b   Muänzer, Thomas ^b   Bellantoni, Michele F ^a   Clair, Carol St ^a   Pabst, Katharine M ^a   Sorkin, John D ^b   Blackman, Marc R ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; DEOXYPYRIDINOLINE; ESTROGEN; OSTEOCALCIN; PROCOLLAGENASE; RECOMBINANT GROWTH HORMONE; SEX HORMONE;

AGED; ARTICLE; BONE DENSITY; BONE METABOLISM; BONE MINERAL; CALCIUM EXCRETION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DOUBLE BLIND PROCEDURE; DRUG EFFECT; ESTROGEN THERAPY; FEMALE; FEMUR NECK; HORMONAL REGULATION; HORMONE BLOOD LEVEL; HUMAN; LONG TERM CARE; LUMBAR SPINE; MAJOR CLINICAL STUDY; MALE; MENOPAUSE; PRIORITY JOURNAL; PROTEIN CROSS LINKING; RADIUS; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE;

AGED; AGED, 80 AND OVER; AGING; BONE AND BONES; BONE DENSITY; DOUBLE-BLIND METHOD; ESTRADIOL; ESTROGEN REPLACEMENT THERAPY; FEMALE; GONADAL STEROID HORMONES; HUMAN GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MALE; RECOMBINANT PROTEINS; REFERENCE VALUES; TESTOSTERONE;

EID: 18244363651     PISSN: 10795006     EISSN: None     Source Type: Journal    
DOI: 10.1093/gerona/57.1.M12     Document Type: Article

References (56)

1. Involutional osteoporosis
2. Bone density at various sites for prediction of hip fractures
3. Human growth hormone and human aging
4. Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore longitudinal study of aging
5. Longitudinal changes in testosterone, luteinizing hormone, and follicle-stimulating hormone in healthy older men
6. Longitudinal relation between endogenous testosterone and cardiovascular disease risk factors in middle-aged men: A 13-year follow-up of former Multiple Risk Factor Intervention Trial participants
7. Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: A key role for bioavailable estrogen
8. Sex steroids and bone mass in older men: Positive associations with serum estrogens and negative associations with androgens
9. Relations of endogenous anabolic hormones and physical activity to bone mineral density and lean body mass in elderly men
10. Marked decline in trabecular bone mineral content in healthy men with age: Lack of association with sex steroid levels
11. Observations on nursing home residents with a history of hip fracture
12. Effects of human growth hormone in men over 60 years old
13. Growth hormone, body composition, and aging
14. Effects of long-term treatment with GH in the bone mineral density of adults with hypopituitarism and GH deficiency and after discontinuation of GH replacement
15. Growth hormone deficiency in adulthood and the effects of growth hormone replacement: A review. Growth Hormone Research Society Scientific Committee
16. Effects of physiologic growth hormone therapy on bone density and body composition in patients with adult-onset growth hormone deficiency: A randomized, placebo-controlled trial
17. Two years of growth hormone (GH) treatment increases bone mineral content and density in hypopituitary patients with adult-onset GH deficiency
18. Consequences of growth hormone deficiency in adults and the benefits and risks of recombinant human growth hormone treatment. A review paper
19. Effect of testosterone on bone density and bone metabolism in adolescent male hypogonadism
20. Does hypogonadism contribute to the occurrence of a minimal trauma hip fracture in elderly men?
21. Effects of six-month administration of recombinant human growth hormone to healthy elderly subjects
22. Effects of hormone therapy on bone mineral density: Results from the postmenopausal estrogen/progestin interventions (PEPI) trial
23. Therapeutic controversy: Estrogen replacement in menopause
24. Menopausal estrogen therapy and hip fractures
25. The effects of estrone (Ogen) on spinal bone density of postmenopausal women
26. The comparative effect on bone density, endometrium, and lipids of continuous hormones as replacement therapy (CHART study)
27. Effects of testosterone replacement therapy in old hypogonadal males: A preliminary study
28. Effects of testosterone supplementation in the aging male
29. Effect of testosterone treatment on bone mineral density in men over 65 years of age
30. Pathophysiology of the neuroregulation of growth hormone secretion in experimental animals and the human
31. Growth hormone and bone metabolism
32. Relationship between circulating insulin-like growth factor components and sex hormones in a population-based sample of 50- to 80-year-old men and women
33. Sex steroids, growth hormone, insulin-like growth factor-1: Neuroendocrine and metabolic regulation in puberty
34. A radioimmunoassay for insulin-like growth factor II specific for the C-peptide region
35. IGF-I resistance and Turner's syndrome
36. Effects of progestin-opposed transdermal estrogen administration on growth hormone and insulin-like growth factor-I in postmenopausal women of different ages
37. Effects of oral versus transdermal estrogen on the growth hormone/insulin-like growth factor I axis in younger and older postmenopausal women: A clinical research center study
38. Growth hormone and bone
39. Effects of recombinant human growth hormone on metabolic indices, body composition, and bone turnover in healthy elderly women
40. Effect of long-term growth-hormone substitution therapy on bone mineral density and parameters of bone metabolism in adult patients with growth hormone deficiency
41. Effects of 12 months of growth hormone (GH) treatment on calciotropic hormones, calcium homeostasis, and bone metabolism in adults with acquired GH deficiency: A double blind, randomized, placebo-controlled study
42. Increased bone density after recombinant human growth hormone (GH) therapy in adults with isolated GH deficiency
43. Bone densitometry: Assessing the effects of growth hormone treatment in adults
44. Effects of short term administration of recombinant human growth hormone to elderly people
45. The benefits of hormone replacement therapy in pre-menopausal women with oestrogen deficiency on haemodialysis
46. Effect of treatment on established osteoporosis in young women with amenorrhoea
47. Alendronate and estrogen-progestin in the long-term prevention of bone loss: Four-year results from the early postmenopausal intervention cohort study. A randomized, controlled trial
48. Estriol (E3) replacement improves endothelial function and bone mineral density in very elderly women
49. Low-dose esterified estrogen therapy: Effects on bone, plasma estradiol concentrations, endometrium, and lipid levels
50. Improved final height in girls with Turner's syndrome treated with growth hormone and oxandrolone
51. Testosterone replacement in older hypogonadal men: A 12-month randomized controlled trial
52. Increase in bone density and lean body mass during testosterone administration in men with acquired hypogonadism
53. Effect of testosterone on radial bone mineral density in adolescent male hypogonadism
54. Effect of testosterone on bone in hypogonadal males
55. Low bone mass in hypogonadal males: Effect of testosterone substitution therapy, a densitometric study
56. Long-term effect of testosterone therapy on bone mineral density in hypogonadal men