Substrate specificity for the 12β-hydroxylation of bufadienolides by Alternaria alternata

Journal of Biotechnology

Volumn 117, Issue 3, 2005, Pages 253-262

  Ye, Min ^a   Guo, Dean ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Alternaria alternata; Biotransformation; Bufadienolide; Hydroxylation; Substrate specificity

Indexed keywords

CYTOLOGY; FUNGI; HIGH PRESSURE LIQUID CHROMATOGRAPHY; HYDROXYLATION; METABOLISM; MICROORGANISMS; SUBSTITUTION REACTIONS; SYNTHESIS (CHEMICAL); TOXIC MATERIALS;

BIOTRANSFORMATION; CYTOTOXICITY; HYDROPHILIC COMPOUNDS; MICROBIAL HYDROXYLATION;

DRUG PRODUCTS;

3 EPI 12BETA HYDROXYLDESACETYLCINOBUFAGIN; 3 EPIDESACETYLCINOBUFAGIN; BUFADIENOLIDE; BUFALIN; BUFOGENIN; CINOBUFAGIN; UNCLASSIFIED DRUG; BUFADIENOLIDE DERIVATIVE; CHOLANE DERIVATIVE;

ALTERNARIA; ARTICLE; BIOTRANSFORMATION; CATALYSIS; DEHYDROGENATION; DRUG HYDROXYLATION; DRUG METABOLISM; DRUG SPECIFICITY; DRUG SUBSTITUTION; FUNGAL STRAIN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INCUBATION TIME; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; SUBSTITUTION REACTION; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; ENZYME SPECIFICITY; HYDROXYLATION; KINETICS; METABOLISM;

ALTERNARIA; ALTERNARIA ALTERNATA; ALTERNATA ALTERNATA;

ALTERNARIA; BIOTRANSFORMATION; BUFANOLIDES; CHOLENES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROXYLATION; KINETICS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SUBSTRATE SPECIFICITY;

EID: 18144418215     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2005.02.002     Document Type: Article

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