Human interleukin-1α gene expression is regulated by Sp1 and a transcriptional repressor

Cytokine

Volumn 30, Issue 4, 2005, Pages 141-153

  McDowell, Tarra L ^a   Symons, Julian A ^a,b   Duff, Gordon W ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b ROCHE BIOSCIENCE   (United States)

Author keywords

Gene regulation; Interleukin 1 ; Repressor protein; Sp1; Transcriptional regulation

Indexed keywords

ANTIBODY; CHLORAMPHENICOL ACETYLTRANSFERASE; DEOXYRIBONUCLEASE I; INTERLEUKIN 1ALPHA; TRANSCRIPTION FACTOR SP1;

ARTICLE; BINDING SITE; CONTROLLED STUDY; GEL MOBILITY SHIFT ASSAY; GENE; GENE DELETION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; INTERLEUKIN 1ALPHA GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; REGULATOR GENE; REPRESSOR GENE; TRANSCRIPTION REGULATION;

FELIS CATUS;

EID: 18144404696     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2004.12.010     Document Type: Article

References (61)

1. C.A. Dinarello Proinflammatory cytokines Chest 118 2000 503 508
2. Y. Furutani, M. Notake, T. Fukui, M. Ohue, H. Nomura, and M. Yamada Complete nucleotide sequence of the gene for human interleukin 1 alpha Nucleic Acids Res 14 1986 3167 3179
3. B.D. Clark, K.L. Collins, M.S. Gandy, A.C. Webb, and P.E. Auron Genomic sequence for human prointerleukin 1 beta: possible evolution from a reverse transcribed prointerleukin 1 alpha gene Nucleic Acids Res 14 1986 7897 7914
4. G. Bensi, G. Raugei, E. Palla, V. Carinci, D.T. Buonamassa, and M. Melli Human interleukin-1 beta gene Gene 52 1987 95 101
5. J.L. Telford, G. Macchia, A. Massone, V. Carinci, E. Palla, and M. Melli The murine interleukin 1α gene: structure and evolution Nucleic Acids Res 14 1986 9955 9963
6. W.S. Modi, A. Masuda, M. Yamada, J.J. Oppenheim, K. Matsushima, and S.J. O'Brien Chromosomal localization of the human interleukin 1 alpha (IL-1 alpha) gene Genomics 2 1988 310 314
7. M. Lafage, N. Maroc, P. Dubreuil, R. de Waal Malefijt, M.J. Pebusque, and Y. Carcassonne The human interleukin-1α gene is located on the long arm of chromosome 2 at band q13 Blood 73 1989 104 107
8. A.C. Webb, K.L. Collins, P.E. Auron, R.L. Eddy, H. Nakai, and M.G. Byers Interleukin 1 gene (IL-1) assigned to long arm of human chromosome 2 Lymphokine Res 5 1986 77 85
9. M. Husmann, P. Jehnichen, B. Jahn, D. Schlosshan, E. Romahn, and J. Marx A novel SP1 site in the human interleukin-1α promoter confers preferential transcriptional activity in keratinocytes Eur J Immunol 26 1996 3008 3014
10. Z. Yang, N. Wara-aswapati, Y. Yoshida, N. Walker, D.L. Galson, and J. Listman Dual regulatory role of human cytomegalovirus immediate-early protein in IL1B transcription is dependent upon Spi-1/PU.1 Biochem Biophys Res Commun 294 2002 854 863
11. J. Tsukada, K. Saito, W.R. Waterman, A.C. Webb, and P.E. Auron Transcription factors NF-IL6 and CREB recognize a common essential site in the human prointerleukin 1 beta gene Mol Cell Biol 14 1994 7285 7297
12. B.G. Monks, B.A. Martell, J.A. Buras, and M.J. Fenton An upstream protein interacts with a distinct protein that binds to the cap site of the human interleukin 1α gene Mol Immunol 31 1994 139 151
13. J. Tsukada, W.R. Waterman, Y. Koyama, A.C. Webb, and P.E. Auron A novel STAT-like factor mediates lipopolysaccharide, interleukin 1 (IL-1) and IL-6 signaling and recognizes a gamma interferon activation site-like element in the IL1B gene Mol Cell Biol 16 1996 2183 2194
14. K. Alheim, T.L. McDowell, J.A. Symons, G.W. Duff, and T. Bartfai An AP-1 site is involved in the NGF induction of IL-1α in PC12 cells Neurochem Int 29 1996 487 496
15. S. Bailly, M. Fay, N. Israel, and M.A. Gougerot-Pocidalo The transcription factor AP-1 binds to the human interleukin 1 alpha promoter Eur Cytokine Netw 7 1996 125 128
16. F. Zaldivar, D.J. Nugent, K. Imfeld, and M.A. Berman Identification of a novel regulatory element in the human interleukin 1 alpha (IL-1α) gene promoter Cytokine 20 2002 130 135
17. N. Mori, and D. Prager Transactivation of the interleukin-1α promoter by human T-cell leukemia virus type I and type II Tax proteins Blood 87 1996 3410 3417
18. Y. Kawaguchi, M. Hara, N. Kamatani, and T.M. Wright Identification of an IL1A gene segment that determines aberrant constitutive expression of Interleukin-1α in systemic sclerosis Arthritis Rheum 48 2003 193 202
19. A.G. Swick, and M.D. Lane Identification of a transcriptional repressor down-regulated during preadipocyte differentiation Proc Natl Acad Sci USA 89 1992 7895 7899
20. R.C. Borghaei, and C. Sullivan Mochan E. Identification of a cytokine-induced repressor of interleukin-1 stimulated expression of stromelysin 1 (MMP-3) J Biol Chem 274 1999 2126 2131
21. M.R. Smith, and W.C. Greene The same 50-kDa cellular protein binds to the negative regulatory elements of the interleukin 2 receptor alpha-chain gene and the human immunodeficiency virus type I long terminal repeat Proc Natl Acad Sci USA 86 1989 8526 8530
22. J.K. Fraser, J.J. Guerra, C.Y. Nguyen, J.E. Indes, J.C. Gasson, and S.D. Nimer Characterization of a cell-type-restricted negative regulatory activity of the human granulocyte-macrophage colony-stimulating factor gene Mol Cell Biol 14 1994 2213 2221
23. T.V. Lebedeva, and A.K. Singh Constitutive activity of the murine IL-1 beta promoter is regulated by a transcriptional repressor Biochim Biophys Acta 1353 1997 32 38
24. T.M. Williams, D. Moolten, J. Burlein, J. Romano, R. Bhaerman, and A. Godillot Identification of a zinc finger protein that inhibits IL-2 gene expression Science 254 1991 1791 1794
25. D.H. Yasui, T. Genetta, T. Kadesch, T.M. Williams, S.L. Swain, and L.V. Tsui Transcriptional repression of the IL-2 gene in Th cells by ZEB J Immunol 160 1998 4433 4440
26. B. Mathey-Prevot, N.C. Andrews, H.S. Murphy, S.G. Kreissman, and D.G. Nathan Positive and negative elements regulate human interleukin 3 expression Proc Natl Acad Sci USA 87 1990 5046 5050
27. S. Georas, J. Cumberland, T. Burke, E. Park, S. Ono, and V. Casolaro Characterization of a novel negative regulatory element in the human interleukin 4 promoter Leukemia 14 2000 629 635
28. U. Santhanam, A. Ray, and P.B. Sehgal Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product Proc Natl Acad Sci USA 88 1991 7605 7609
29. C. Kannabiran, X. Zeng, and L.D. Vales The mammalian transcriptional repressor RBP (CBF1) regulates interleukin-6 gene expression Mol Cell Biol 17 1997 1 9
30. M. Nourbakhsh, S. Kalble, A. Dorrie, H. Hauser, K. Resch, and M. Kracht The NF-κB repressing factor is involved in basal repression and interleukin (IL)-1-induced activation of IL-8 transcription by binding to a conserved NF-κB-flanking sequence element J Biol Chem 276 2001 4501 4508
31. 2 J Immunol 167 2001 2608 2618
32. M. Nourbakhsh, and H. Hauser Constitutive silencing of IFN-beta promoter is mediated by NRF (NF-kappaB-repressing factor), a nuclear inhibitor of NF-kappaB EMBO J 18 1999 6415 6425
33. S.J. Fashena, W.L. Tang, T. Sarr, and N.H. Ruddle The murine lymphotoxin gene promoter. Characterization and negative regulation J Immunol 145 1990 177 183
34. P.J. Barnes, and M. Karin Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases N Engl J Med 336 1997 1066 1071
35. Y. Furutani Molecular studies on interleukin 1α Eur Cytokine Netw 5 1994 533 538
36. Y. Kawaguchi IL-1α gene expression and protein production by fibroblasts from patients with systemic sclerosis Clin Exp Immunol 97 1994 445 450
37. G. Suske The Sp-family of transcription factors Gene 238 1999 291 300
38. P. Bouwman, and S. Philipsen Regulation of the activity of Sp1-related transcription factors Mol Cell Endocrinol 195 2002 27 38
39. A.R. Black, J.D. Black, and J. Azizkhan-Clifford Sp1 and Kruppel-like factor family of transcription factors in cell growth regulation and cancer J Cell Physiol 188 2001 143 160
40. J.D. Saffer, S.P. Jackson, and M.B. Annarella Developmental expression of Sp1 in the mouse Mol Cell Biol 11 1991 2189 2199
41. C.Y. Yu, K. Motamed, J. Chen, A.D. Bailey, and C.K. Shen The CACC box upstream of the human embryonic ε globin gene binds Sp1 and is a functional promoter in vitro and in vivo J Biol Chem 266 1991 8907 8915
42. D.L. Gumucio, K.L. Rood, K.L. Blanchard-McQuate, T.A. Gray, A. Saulino, and F.S. Collins Interaction of Sp1 with the human γ globin promoter: binding and transactivation of normal and mutant promoters Blood 78 1991 1853 1863
43. S.M. Jane, D.L. Gumucio, P.A. Ney, J.M. Cunningham, and A.W. Nienhuis Methylatyion-enhanced binding of Sp1 to the stage selector element of the human γ-globin gene promoter may regulate developmental specificity of expression Mol Cell Biol 13 1993 3272 3281
44. E. Spanopoulou, V. Giguere, and F. Grosveld The functional domains of the murine Thy-1 gene promoter Mol Cell Biol 11 1991 2216 2228
45. H.M. Chen, H.L. Pahl, R.J. Scheibe, D.E. Zhang, and D.G. Tenen The Sp1 transcription factor binds the CD11b promoter specifically in myeloid cells in vivo and is essential for myeloid-specific promoter activity J Biol Chem 268 1993 8230 8239
46. D.E. Zhang, C.J. Hetherington, S. Tan, S.E. Dziennis, D.A. Gonzalez, and H.M. Chen Sp1 is a critical factor for the monocytic specific expression of human CD14 J Biol Chem 269 1994 11425 11434
47. E. Akagawa, A. Muto, K. Arai, and S. Watanabe Analysis of the 5′ promoters for human IL-3 and GM-CSF receptor alpha genes Biochem Biophys Res Commun 300 2003 600 608
48. S.H. Kang, D.A. Brown, I. Kitajima, X. Xu, O. Heidenreich, and S. Gryaznov Binding and functional effects of transcription factor Sp1 on the murine interleukin 6 promoter J Biol Chem 271 1996 7330 7335
49. J. Sanceau, T. Kaisho, T. Hirano, and J. Wietzerbin Triggering of the human interleukin-6 gene by interferon-γ and tumor necrosis factor-α in monocytic cells involves cooperation between interferon regulatory factor 1, NF-κB and Sp1 transcription factors J Biol Chem 270 1995 27920 27931
50. M. Tone, M.J. Powell, Y. Tone, S.A. Thompson, and H. Waldmann IL-10 gene expression is controlled by the transcription factors Sp1 and Sp3 J Immunol 165 2000 286 291
51. H.D. Brightbill, S.E. Plevy, R.L. Modlin, and S.T. Smale A prominent role for Sp1 during lipopolysaccharide-mediated induction of the IL-10 promoter in macrophages J Immunol 164 2000 1940 1951
52. S. Goriely, D. Demonte, S. Nizet, D. De Wit, F. Willems, and M. Goldman Human IL-12(p35) gene activation involves selective remodeling of a single nucleosome within a region of the promoter containing critical Sp1 binding sites Blood 101 2003 4894 4902
53. L.D. Wood, A.A. Farmer, and A. Richmond HMGI(Y) and Sp1 in addition to NF-kappa B regulate transcription of the MSGA/GRO alpha gene Nucleic Acids Res 23 1995 4210 4219
54. A. Ueda, K. Okuda, S. Ohno, A. Shirai, T. Igarashi, and K. Matsunaga NF-kappa B and Sp1 regulate transcription of the human monocyte chemoattractant protein-1 gene J Immunol 153 1994 2052 2063
55. D. Ping, G. Boekhoudt, F. Zhang, A. Morris, S. Philipsen, and S.T. Warren Sp1 binding is critical for promoter assembly and activation of the MCP-1 gene by tumour necrosis factor J Biol Chem 275 2000 1708 1714
56. G.H. Boekhoudt, Z. Guo, G.W. Beresford, and J.M. Boss Communication between NF-kappaB and Sp1 controls histone acetylation within the proximal promoter of monocyte chemoattractant protein 1 gene J Immunol 170 2003 4139 4147
57. S.E. Francis, and G.W. Duff 7B6, a ubiquitous mRNA: with significant homology to L41 human ribosomal protein RNA Nucleic Acids Res 21 1993 2944
58. B. Luckow, and G. Schutz CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements Nucleic Acids Res 15 1987 5490
59. H. Abken, and B. Reifenrath A procedure to standardize CAT reporter gene assay Nucleic Acids Res 20 1992 3527
60. N.C. Andrews, and D.V. Faller A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells Nucleic Acids Res 19 1991 2499
61. J. Sambrook, and D.W. Russel Protocol 7 - Chemical sequencing J. Sambrook D.W. Russel Molecular cloning: a laboratory manual 3rd ed 2001 Cold Spring Harbor Laboratory Press Cold Spring Harbor, NY 12.61 12.73