Identification of a novel regulatory element in the human interleukin 1 alpha (IL-1α) gene promoter

Cytokine

Volumn 20, Issue 3, 2002, Pages 130-135

  Zaldivar Jr , Frank ^a   Nugent, Diane J ^a   Imfeld, Karen ^a   Berman, Monique A ^a  

^a CHILDREN S HOSPITAL OF ORANGE COUNTY   (United States)

Author keywords

Cytokines; Gene regulation; Growth factors; Interleukin 1 (IL 1 ); Transcription factors

Indexed keywords

DEOXYRIBONUCLEASE; DEOXYRIBONUCLEASE I; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1ALPHA; NUCLEOTIDE; TRANSCRIPTION FACTOR; DNA BINDING PROTEIN; INTERLEUKIN 1;

ARTICLE; BINDING SITE; CELL LINE; CONTROLLED STUDY; DNA PROTEIN COMPLEX; EPITHELIUM CELL; ERYTHROLEUKEMIA CELL; GEL MOBILITY SHIFT ASSAY; GENE; GENE ACTIVITY; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INTERLEUKIN 1ALPHA GENE PROMOTER; NUCLEOTIDE REPEAT; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN MOTIF; REGULATORY MECHANISM; SEQUENCE HOMOLOGY; CELL CULTURE; DNA FOOTPRINTING; DNA RESPONSIVE ELEMENT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; NUCLEOTIDE SEQUENCE;

BASE SEQUENCE; CELL LINE; DNA FOOTPRINTING; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-1; MOLECULAR SEQUENCE DATA; MUTATION; PROMOTER REGIONS (GENETICS); RESPONSE ELEMENTS; SEQUENCE HOMOLOGY; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0036436371     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.2002.1990     Document Type: Article

References (26)

1. Dinarello CA (1996) Biologic basis for Interleukin 1 in Disease. Blood 87:2095-2147.
2. Mangge H, Kenzian H, Gallistl S, Neuwirth G, Liebmann P, Kaulfersch W, Beaufort F, Muntean W, Schauenstein K (1995) Serum cytokines in juvenile rheumatoid arthritis. Arthritis Rheum 38:211-220.
3. Lundberg I, Ulfgren A, Nyberg P, Andersson U, Klareskog L (1997) Cytokine production in muscle tissue of patients with idiopathic inflammatory myopathies. Arthritis Rheum 40:865-874.
4. Kawaguchi Y, Hara M, Wright T (1999) Endogenous IL-1α from systemic sclerosis fibroblasts induces IL-6 and PDGF-A. J Clin Invest 103:1253-1260.
5. Kornborg G, Hansen MB, Svenson M, Fomsgaard A, Hoiby N, Bendtzen K (1993) Cytokines in sputum and serum from patients with cystic fibrosis and chronic pseudomonas aeruginosa infection as markers of destructive inflammation in the lungs. Pediatr Pulmon 15:292-297.
6. Sandborg CI, Berman MA, Imfeld KI, Cesario TC, Zaldivar F (1990) Interleukin 1 and a 7-kDa T cell inhibitory monokine reflect disease activity in infection with HIV-1. J Acquired Immun Deficiency Syndr 3:1148-1154.
7. Tomimatsu S, Ichikura T, Mochizuki H (2001) Significant correlation between expression of Interleukin 1α and liver metastasis in gastric carcinoma. Cancer 91:1272-1276.
8. Huleihel M, Maymon E, Piura B, Prinsloo I, Benharroch D, Yanai-Inbar I, Glezerman M (1997) Distinct patterns of expression of Interleukin 1α and β by normal and cancerous human ovarian tissue. Eur Cytok Netw 8:179-187.
9. Soder O, Sultana T, Jonsson C, Wahlgren A, Petersen C, Holst M (2000) The Interleukin-1 system in the testis. Andrologia 32:52-55.
10. Yang ZM, Chen DB, Le SP, Harper MJ (1995) Interleukin 1α in the rabbit uterus during early pregnancy. Early Pregnancy, Biol Med 1:201-205.
11. West-Mays JA, Sadow PM, Tobin TW, Strissel KJ, Cintron C, Fini EM (1997) Repair phenotype in corneal fibroblasts is controlled by an Interleukin 1α autocrine feedback loop. Invest Ophthalm Visual Sci 38:1367-1379.
12. Burysek L, Houstek J (1996) Multifactorial induction of gene expression and nuclear localization of mouse Interleukin 1α. Cytokine 8:460-467.
13. Sim JE, Nicklin M, Bazan JF, Barton JL, Busfield SJ, Ford JE, Kastelein RA, Kumar S, Lin H, Mulero JJ, Pan JG, Pan Y, Smith DE, Young PR (2001) A new nomenclature for IL-1 family genes. Trends Immunol 22:536-537.
14. Auron PE, Webb AC (1994) Interleukin 1: A gene expression system regulated at multiple levels. Eur Cytok Netw 5:573-592.
15. Tsukada J, Saito K, Waterman WR, Webb AC, Auron PE (1994) Transcription factors NF-IL-6 and CREB recognize a common essential site in the human prointerleukin 1β gene. Mol Cell Biol 14:7285-7297.
16. Tsukada J, Waterman WR, Koyama Y, Webb AC, Auron PE (1996) A novel STAT-like factor mediates lipopolysaccharide, Interleukin 1 (IL-1) and IL-6 signaling and recognizes a γ interferon activation site-like element in the IL-1B gene. Mol Cell Biol 16:2183-2194.
17. Monks BG, Martell BA, Buras JA, Fenton MJ (1994) An upstream protein interacts with a distinct protein that binds to the cap site of the human interleukin 1β gene. Mol Immunol 31:139-151.
18. Berman MA, Zaldivar F, Imfeld KI, Kenney JS, Sandborg CI (1994) HIV-1 infection in macrophages promotes long-term survival and sustained release of Interleukins 1α and 6. AIDS Res Hum Retrovirus 10:529-539.
19. Waterman ML, Jones KA (1990) Purification of TCF-1α, a T-cell specific transcription factor that activates the T-cell receptor Cα gene enhancer in a context dependent manner. New Biol 2:621-636.
20. Furutani Y (1994) Molecular studies on interleukin 1α. Eur Cytok Netw 5:533-538.
21. Alheim K, McDowell TL, Symons JA, Duff GW, Bartfai T (1996) An AP-1 site is involved in the NGF induction of IL-1α in PC12 cells. Neurochem Int 29:487-496.
22. Bailly S, Israel N, Fay M, Gougerot-Pocidalo MA, Duff GW (1996) An intronic polymorphic repeat sequence modulates Interleukin 1α gene regulation. Mol Immunol 33:999-1006.
23. Mori N, Prager D (1996) Transactivation of the Interleukin 1α promoter by human T-cell leukemia virus Type I and Type II Tax proteins. Blood 87:3410-3417.
24. van den Berg WB, Bresnihan B (1999) Pathogenesis of joint damage in rheumatoid arthritis: Evidence of a dominant role for interleukin-1. Baillieres Best Practice Res Clin Rheumatol 13:577-597.
25. Arend WP (2001) Cytokine imbalance in the pathogenesis of rheumatoid arthritis: The role of interleukin-1 receptor antagonist. Semin Arthritis Rheumatol 30:1-6.
26. Furutani Y, Notake M, Fukui T, Ohue M, Nomura H, Yamada M, Nakamura S (1986) Complete nucleotide sequence of the gene for human interleukin 1 alpha. Nucleic Acids Res 14:3167-3179.