Advancements in the anti-diabetes chemotherapeutics based on amino acids, peptides, and peptidomimetics

Mini-Reviews in Medicinal Chemistry

Volumn 5, Issue 5, 2005, Pages 469-477

  Jain, Rahul ^a   Chawrai, Suresh ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Diabetes; Non proteinogenic amino acids; Peptides; Peptidomimetics

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; 4 HYDROXYISOLEUCINE; AMINO ACID DERIVATIVE; ANTIDIABETIC AGENT; CJC 1131; DEXTRO PHENYLALANINE; DIPEPTIDYL PEPTIDASE IV INHIBITOR; EXENDIN 4; GASTRIC INHIBITORY POLYPEPTIDE; GLUCAGON LIKE PEPTIDE 1 D12; GLUCAGON LIKE PEPTIDE 1 D21; GLUCAGON LIKE PEPTIDE 1 D3; GLUCAGON LIKE PEPTIDE 1 D5; GLUCAGON LIKE PEPTIDE 1 D8; GLUCAGON LIKE PEPTIDE 1 DERIVATIVE; GLUCOSE; GROWTH HORMONE DERIVATIVE; INSULIN DERIVATIVE; ISOLEUCINE THIAZOLIDIDE; LIRAGLUTIDE; LY 315902; MOMORDICA CHARANTIA EXTRACT; N (4 ETHYLBENZOYL) DEXTRO PHENYLALANINE; N (CYCLOHEXYLCARBONYL) DEXTRO PHENYLALANINE; N BENZOYL DEXTRO PHENYLALANINE; NATEGLINIDE; PEPTIDE DERIVATIVE; PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR; SULFONYLUREA; UNCLASSIFIED DRUG; UNINDEXED DRUG;

BLOOD GLUCOSE MONITORING; CLINICAL TRIAL; DIABETES MELLITUS; DRUG ABSORPTION; DRUG DESIGN; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG ISOLATION; DRUG PURIFICATION; DRUG SAFETY; DRUG SYNTHESIS; HUMAN; HYPOGLYCEMIA; IN VITRO STUDY; IN VIVO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; LIVER TOXICITY; NEPHROTOXICITY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; REVIEW; STRUCTURE ACTIVITY RELATION;

AMINO ACIDS; DIABETES MELLITUS; GASTRIC INHIBITORY POLYPEPTIDE; GLUCAGON; GLUCAGON-LIKE PEPTIDE 1; HUMANS; HYPOGLYCEMIC AGENTS; MOLECULAR MIMICRY; PEPTIDE FRAGMENTS; PEPTIDES; PROTEIN PRECURSORS;

EID: 18044375550     PISSN: 13895575     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389557053765583     Document Type: Review

References (55)

1. Hardman, J.G.; Limbird, L.E. In Goodman and Gilman's: The Pharmacological Basis of Therapeutics; 10; McGraw-Hill: New York, 2001; pp. 1679-1714.
2. White, J.R.; Davis, S.N.; Cooppan, R.; Davidson, B.M.; Mulcahy, K.; Manko, G.A.; Nelinson, D. Diabetes 2003, 21 , 14.
3. Witt, K.N.; Gillespie, T.J.; Huber, J.D.; Egleton, R.D.; Dacis, T.P. Peptides 2001, 22, 2329.
4. Broca, C.; Gross, R.; Petit, P.; Sauvaire, Y.; Manteghetti, M.; Tournier, M.; Masiello, P.; Gomis, R.; Ribes, G. Am. J. Physiol. 1999, 277, 617.
5. Sauvaire, Y.; Petit, P.; Broca, C.; Manteghetti, M.; Baissac, Y.; Fernandez-Alvarez, J.; Gross, R.; Roye, M.; Leconte, A.; Gomis, R.; Ribes, G. Diabetes 1998, 16, 206.
6. Shinkai, H.; Toi, K.; Kumashiro, I.; Seto, Y.; Fukuma, M.; Dan, K.; Toyoshima, S. J. Med. Chem. 1988, 31, 2092.
7. Shinkai, H.; Nishikawa, M.; Sato, Y.; Toi, K.; Kumashiro, I.; Seto, Y.; Fukuma, M.; Dan, K.; Toyoshima, S. J. Med. Chem. 1989 , 32, 1436.
8. Takesada, H.; Matsuda, K.; Ohtake, R.; Mihara, R.; Ono, I.; Tanaka, K.; Naito, M.; Yatagai, M.; Suzuki, E. Bioorg. Med. Chem. 1996, 4, 1771.
9. Zhang, B.B.; Moller, D.E. Curr. Opin. Chem. Biol. 2000, 4, 461.
10. Ali, L.; Kahn, A.K.; Mammun, M.I.; Mosihuzzaman, M.; Nahar, N.; Nur-e-Alam, M.; Rokeya, B. Planta Med. 1993, 56, 408.
11. Shibib, B.A.; Khan, L.A.; Rahman, R. Biochem. J. 1993, 292 (Pt 1), 267.
12. Akhtar, M.S.; Athar, M.A.; Yaqub, M. Planta. Med. 1981, 42, 205.
13. Sitasawad, S.L.; Shewade, Y.; Bhonde, R. J. Ethnopharmacol. 2000, 73, 71.
14. Virdi, J.; Sivakami, S.; Shahani, S.; Suthar, A.C.; Banavalikar, M.M.; Biyani, M.K. J. Ethnopharmacol. 2003, 88, 107.
15. Patzelt, C.; Schiltz, E. Proc. Natl. Acad. Sci. U.S.A. 1984, 81, 5007.
16. Mojsov, S.; Heinrich, G.; Wilson, J.B.; Ravazzola, M.; Orci, L.; Habener, J.F. J. Biol. Chem. 1986, 261, 11880.
17. Orscov, C.; Holst, J.J.; Seier, P.S.; Kirkegaard, P. Diabetologia 1986, 30, 874-881.
18. Drucker, D. J. Diabetes 1998, 47, 159.
19. Kieffer, T.J.; McIntosh, C.H.S.; Pederson, R.A. Endocrinology 1995, 136, 3585.
20. Deacon, C.F.; Johnsen, A.H.; Holst, J.J. J. Clin. Endocrinol. Metab. 1995, 80, 952.
21. Mentlein, R.; Gallwitz, B.; Schmidt, W.E Eur. J. Biochem. 1993, 214, 829.
22. Hansen, L.; Deacon, C.F.; Orskow, C.; Holst J.J. Endocrinology 1999, 140, 5356.
23. Nauck, M.A.; Holst, J.J.; Willms, B.; Schmiegel, W. Exp. Clin. Endocrinol. Diabetes 1997, 105, 187.
24. Deacon, C.F.; Holst, J.J.; Carr, R.D. Drugs of Today 1999, 35, 159.
25. Siegel, E.G.; Gallwitz, B.; Scharf, G.; Mentlein, R.; Morys-Wortmann, C.; Folsch, U.R.; Schrezenmeir, J.; Drescher, K.; Schmidt, W.E. Regul. Peptides 1999, 79, 93.
26. Holz, G.G.; Chepurny, O.G. Curr. Med. Chem. 2003, 10, 2471.
27. Chang, A.M.; Jakobsen, G.; Sturis, J.; An, B.; Smith, M.J.; Bloem, C.J.; Galecki, A.; Halter, J.B. In Diabetes (New Horizons in Diabetes Therapy Conference Highlights ADA 63rd Scientific Sessions 13-17 June 2003 New Orleans, USA). 2003, 52 (suppl. 1), 486-P.
28. Elbrond, B.; Jakobsen, G.; Larsen, S.; Agerso, H.; Jensen, L.B.; Rolan, P.; Sturis, J.; Hatorp, V.; Zdravkovic, M. Diabetes Care 2002, 25, 1398.
29. Agerso, H.; Jensen, L.B.; Elbrond, B.; Rolan, P.; Zdravkovic, M. Diabetologia 2002, 45, 195.
30. Agerso, H.; Vicino, P. Eur. J. Pharm. Sci. 2003, 19, 141.
31. Deacon, C.F.; Knudsen, L.B.; Madsen, K.; Wiberg, F.C.; Jacobsen, O.; Holst, J.J. Diabetologia 1998, 41, 271.
32. Doyle, M.E.; Greig, N.H.; Holloway, H.W.; Betkay, J.A.; Bernier, M.; Egan, J. M. Endocrinology 2001, 142, 4462.
33. Mohler, D.L.; Shena, G.; Dotseb, A.K. Bioorg. Med. Chem. Lett. 2000, 10, 2239.
34. Lim, N.; Ng, F.M.; Wu, Z.M.; Ede, N.; Hearn, M.T.W. Endocrinology 1992, 131, 835.
35. Ede, N.J.; Rae, I.D.; Hearn, M.T. W. Int. J. Peptide Protein Res. 1994, 44, 568.
36. Hinke, S.A.; Gelling, R.W.; Pederson, R.A.; Manhart, S.; Nian, C.; Demuth, H.-U.; McIntosh, C.H.S. Diabetes 2002, 51, 652.
37. Abdel-Wahab, Y.H.; Marenah, L.; Shaw, C.; Flatt, P.R. Diabetologia 2002, 45 (suppl. 1), A178.
38. Wrobel, J.; Sredy, J.; Moxham, C.; Dietrich, A.; Li, Z.; Sawicki, D.R.; Seestaller, L.; Wu, L.; Katz, A.; Sullivan, D.; Tio, C.; Zhang, Z.Y. J. Med. Chem. 1999, 42, 3199.
39. Malamas, M.S.; Sredy, J.; Moxham, C.; Katz, A.; Xu, W.X.; McDevitt, R.; Adebayo, F.O.; Sawicki, D.R.; Seestaller, L.; Sullivan, D.; Taylor, J.R. J. Med. Chem. 2000, 43, 1293.
40. Iversen, L.F.; Andersen, H.S.; Branner, S.; Mortensen, S.B.; Peters, G.H.; Norris, K.; Olsen, O.H.; Jeppesen, C.B.; Lundt, B.F.; Ripka, W.; Moller, K.B.; Moller, N.P.H. J. Biol. Chem. 2000, 275, 10300.
41. Gao, Y.; Wu, L.; Luo, J.H.; Guo, R.; Yang, D.; Zhang, Z.Y.; Burke, T. R. Bioorg. Med. Chem. Lett. 2000, 10, 923.
42. Yu, L.; McGill, A.; Ramirez, J.; Wang, P.G.; Zhang, P.G. Bioorg. Med. Chem. Lett. 1995, 5, 1003.
43. Ham, S. W.; Park, J.G.; Lee, S.J.; Yoo, J.S. Bioorg. Med. Chem. Lett. 1999, 9, 185.
44. Seely, B.L.; Staubs, P.A.; Reichart, D.R.; Berhanu, P.; Milarski, K.L.; Saltiel, A.R.; Kusari, J.; Olefsky, J.M. Diabetes 1996, 45, 1379.
45. Wang, X.Y.; Bergdahl, K.; Heijbel, A.; Liljebris, C.; Bleasdale, J.E. Mol. Cell. Endocrinol. 2001, 173, 109.
46. Bandyopadhyay, D.; Kusari, A.; Kenner, K.A.; Liu, F.; Chernoff, J.; Gustafson, T.A.; Kusari, J. J. Biol. Chem. 1997 , 272, 1639.
47. Ramachandran, C.; Aebersold, R.; Tonks, N.K.; Pot, D.A. Biochemistry 1992, 31, 4232.
48. Bleasdale, J.E.; Ogg, D.; Palazuk, B.J.; Jacob, C.S.; Swanson, M.L.; Wang, X.; Thompson, D.P.; Conradi, R.A.; Mathews, W.R.; Laborde, A.L.; Stuchly, C.W.; Heijbel, A.; Bergdahl, K.; Bannow, C.A.; Smith, C.W.; Svensson, C.; Liljebris, C.; Schostarez, H.J.; May, P.D.; Stevens, F.C.; Larsen, S.D. Biochemistry 2001, 40, 5642.
49. Shen, K.; Keng, Y.-F.; Wu, L.; Guo, X.-L.; Lawrence, D. S.; Zhang, Z.-Y. J. Biol. Chem. 2001, 276, 47311.
50. Kole, H.K.; Akamatsu, M.; Ye, B.; Yan, X.; Barford, D.; Roller, P.P.; Burke, T.R. Biochem. Biophys. Res. Commun. 1995 , 209, 817.
51. Ye, B.; Akamatsu, M.; Shoelson, S.E.; Wolf, G.; Giorgetti-Peraldi, S.; Yan, X.; Roller, P.P.; Burke, T.R. J. Med. Chem. 1995, 38, 4270.
52. Burke, T.R.; Ye, B.; Akamatsu, M.; Ford, H.; Yan, X.; Kole, H.K.; Wolf, G.; Shoelson, S.E.; Roller, P.P. J. Med. Chem. 1996 , 39, 1021.
53. Zhang, Z.Y.; Maclean, D.; McNamara, D.J.; Sawyer, T.K.; Dixon, J.E. Biochemistry 1994, 33, 2285.
54. Akamatsu, M.; Roller, P.P.; Chen, L.; Zhang, Z.Y.; Ye, B.; Burke, T.R. Bioorg. Med. Chem. 1997, 5, 157.
55. Burke, T.R.; Yao, Z.J.; Zhao, H.; Milne, G.W.A.; Wu, L.; Zhang, Z.Y.; Voigt, J.H. Tetrahedron 1998, 54, 9981.