-
2
-
-
0031734471
-
Stable and inheritable changes in genotype and phenotype of albino melanocytes induced by an RNA-DNA oligonucleotide
-
Alexeev V, Yoon K. 1998. Stable and inheritable changes in genotype and phenotype of albino melanocytes induced by an RNA-DNA oligonucleotide. Nat Biotechnol 16:1343-1346.
-
(1998)
Nat Biotechnol
, vol.16
, pp. 1343-1346
-
-
Alexeev, V.1
Yoon, K.2
-
3
-
-
0033989521
-
Localized in vivo genotypic and phenotypic correction of the albino mutation in skin by RNA-DNA oligonucleotide
-
Alexeev V, Igoucheva O, Domashenko A, Cotsarelis G, Yoon K. 2000. Localized in vivo genotypic and phenotypic correction of the albino mutation in skin by RNA-DNA oligonucleotide. Nat Biotechnol 18:43-47.
-
(2000)
Nat Biotechnol
, vol.18
, pp. 43-47
-
-
Alexeev, V.1
Igoucheva, O.2
Domashenko, A.3
Cotsarelis, G.4
Yoon, K.5
-
4
-
-
0033537836
-
Nucleotide exchange in genomic DNA of rat hepatocytes using RNA/DNA oligonucleotides. Targeted delivery of liposomes and polyethyleneimine to the asialoglycoprotein receptor
-
Bandyopadhyay P, Ma X, Linehan-Stieers C, Kren BT, Steer CJ. 1999. Nucleotide exchange in genomic DNA of rat hepatocytes using RNA/DNA oligonucleotides. Targeted delivery of liposomes and polyethyleneimine to the asialoglycoprotein receptor. J Biol Chem 274:10163-10172.
-
(1999)
J Biol Chem
, vol.274
, pp. 10163-10172
-
-
Bandyopadhyay, P.1
Ma, X.2
Linehan-Stieers, C.3
Kren, B.T.4
Steer, C.J.5
-
5
-
-
4444335574
-
DNA replication and transcription direct a DNA strand bias in the process of targeted gene repair in mammalian cells
-
Brachman EE, Kmiec EB. 2004. DNA replication and transcription direct a DNA strand bias in the process of targeted gene repair in mammalian cells. J Cell Sci 117:3867-3874.
-
(2004)
J Cell Sci
, vol.117
, pp. 3867-3874
-
-
Brachman, E.E.1
Kmiec, E.B.2
-
6
-
-
0001305936
-
Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs
-
Brinster RL, Chen HY, Trumbauer ME, Yagle MK, Palmiter RD. 1985. Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs. Proc Natl Acad Sci USA 82:4438-4442.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 4438-4442
-
-
Brinster, R.L.1
Chen, H.Y.2
Trumbauer, M.E.3
Yagle, M.K.4
Palmiter, R.D.5
-
7
-
-
0034091810
-
Genotype-based screen for ENU-induced mutations in mouse embryonic stem cells
-
Chen Y, Yee D, Dains K, Chatterjee A, Cavalcoli J, Schneider E, Om J, Woychik RP, Magnuson T. 2000. Genotype-based screen for ENU-induced mutations in mouse embryonic stem cells. Nat Genet 24:314-317.
-
(2000)
Nat Genet
, vol.24
, pp. 314-317
-
-
Chen, Y.1
Yee, D.2
Dains, K.3
Chatterjee, A.4
Cavalcoli, J.5
Schneider, E.6
Om, J.7
Woychik, R.P.8
Magnuson, T.9
-
8
-
-
0029817766
-
Correction of the mutation responsible for sickle cell anemia by an RNA-DNA oligonucleotide
-
Cole-Strauss A, Yoon K, Xiang Y, Byrne BC, Rice MC, Gryn J, Holloman WK, Kmiec EB. 1996. Correction of the mutation responsible for sickle cell anemia by an RNA-DNA oligonucleotide. Science 273:1386-1389.
-
(1996)
Science
, vol.273
, pp. 1386-1389
-
-
Cole-Strauss, A.1
Yoon, K.2
Xiang, Y.3
Byrne, B.C.4
Rice, M.C.5
Gryn, J.6
Holloman, W.K.7
Kmiec, E.B.8
-
9
-
-
0032874955
-
Correction of chromosomal point mutations in human cells with bifunctional oligonucleotides
-
Culver KW, Hsieh WT, Huyen Y, Chen V, Liu J, Khripine Y, Khorlin A. 1999. Correction of chromosomal point mutations in human cells with bifunctional oligonucleotides. Nat Biotechnol 17:989-993.
-
(1999)
Nat Biotechnol
, vol.17
, pp. 989-993
-
-
Culver, K.W.1
Hsieh, W.T.2
Huyen, Y.3
Chen, V.4
Liu, J.5
Khripine, Y.6
Khorlin, A.7
-
10
-
-
0036246160
-
Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation
-
Eggan K, Rode A, Jentsch I, Samuel C, Hennek T, Tintrup H, Zevnik B, Erwin J, Loring J, Jackson-Grusby L, Speicher MR, Kuehn R, Jaenisch R. 2002. Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation. Nat Biotechnol 20:455-459.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 455-459
-
-
Eggan, K.1
Rode, A.2
Jentsch, I.3
Samuel, C.4
Hennek, T.5
Tintrup, H.6
Zevnik, B.7
Erwin, J.8
Loring, J.9
Jackson-Grusby, L.10
Speicher, M.R.11
Kuehn, R.12
Jaenisch, R.13
-
11
-
-
5144232273
-
Camptothecin enhances the frequency of oligonucleotide-directed gene repair in mammalian cells by inducing DNA damage and activating homologous recombination
-
Ferrara L, Kmiec EB. 2004. Camptothecin enhances the frequency of oligonucleotide-directed gene repair in mammalian cells by inducing DNA damage and activating homologous recombination. Nucleic Acids Res 32:5239-5248.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 5239-5248
-
-
Ferrara, L.1
Kmiec, E.B.2
-
12
-
-
4644339733
-
Enhanced oligonucleotide-directed gene targeting in mammalian cells following treatment with DNA damaging agents
-
Ferrara L, Parekh-Olmedo H, Kmiec EB. 2004. Enhanced oligonucleotide- directed gene targeting in mammalian cells following treatment with DNA damaging agents. Exp Cell Res 300:170-179.
-
(2004)
Exp Cell Res
, vol.300
, pp. 170-179
-
-
Ferrara, L.1
Parekh-Olmedo, H.2
Kmiec, E.B.3
-
13
-
-
0034626882
-
Paternal exposure to cyclophosphamide induces DNA damage and alters the expression of DNA repair genes in the rat preimplantation embryo
-
Harrouk W, Codrington A, Vinson R, Robaire B, Hales BF. 2000. Paternal exposure to cyclophosphamide induces DNA damage and alters the expression of DNA repair genes in the rat preimplantation embryo. Mutat Res 461:229-241.
-
(2000)
Mutat Res
, vol.461
, pp. 229-241
-
-
Harrouk, W.1
Codrington, A.2
Vinson, R.3
Robaire, B.4
Hales, B.F.5
-
15
-
-
0034425715
-
Genome-wide, large-scale production of mutant mice by ENU mutagenesis
-
Hrabe de Angelis MH, Flaswinkel H, Fuchs H, Rathkolb B. et al. 2000. Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nat Genet 25:444-447.
-
(2000)
Nat Genet
, vol.25
, pp. 444-447
-
-
Hrabe De Angelis, M.H.1
Flaswinkel, H.2
Fuchs, H.3
Rathkolb, B.4
-
16
-
-
0037705453
-
Transcription affects formation and processing of intermediates in oligonucleotide-mediated gene alteration
-
Igoucheva O, Alexeev V, Pryce M, Yoon K. 2003. Transcription affects formation and processing of intermediates in oligonucleotide-mediated gene alteration. Nucleic Acids Res 31:2659-2670.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 2659-2670
-
-
Igoucheva, O.1
Alexeev, V.2
Pryce, M.3
Yoon, K.4
-
17
-
-
0036929417
-
Targeted gene correction of hprt mutations by 45 base single-stranded oligonucleotides
-
Kenner O, Kneisel A, Klingler J, Bartelt B, Speit G, Vogel W, Kaufmann D. 2002. Targeted gene correction of hprt mutations by 45 base single-stranded oligonucleotides. Biochem Biophys Res Commun 299:787-792.
-
(2002)
Biochem Biophys Res Commun
, vol.299
, pp. 787-792
-
-
Kenner, O.1
Kneisel, A.2
Klingler, J.3
Bartelt, B.4
Speit, G.5
Vogel, W.6
Kaufmann, D.7
-
18
-
-
0030913556
-
Targeted nucleotide exchange in the alkaline phosphatase gene of HuH-7 cells mediated by a chimeric RNA/DNA oligonucleotide
-
Kren BT, Cole-Strauss A, Kmiec EB, Steer CJ. 1997. Targeted nucleotide exchange in the alkaline phosphatase gene of HuH-7 cells mediated by a chimeric RNA/DNA oligonucleotide. Hepatology 25:1462-1468.
-
(1997)
Hepatology
, vol.25
, pp. 1462-1468
-
-
Kren, B.T.1
Cole-Strauss, A.2
Kmiec, E.B.3
Steer, C.J.4
-
19
-
-
0031953132
-
In vivo site-directed mutagenesis of the factor IX gene by chimeric RNA/DNA oligonucleotides
-
Kren BT, Bandyopadhyay P, Steer CJ. 1998. In vivo site-directed mutagenesis of the factor IX gene by chimeric RNA/DNA oligonucleotides. Nat Med 4:285-290.
-
(1998)
Nat Med
, vol.4
, pp. 285-290
-
-
Kren, B.T.1
Bandyopadhyay, P.2
Steer, C.J.3
-
20
-
-
0033621041
-
Correction of the UDP-glucuronosyltransferase gene defect in the Gunn rat model of Crigler-Najjar syndrome type I with a chimeric oligonucleotide
-
Kren BT, Parashar B, Bandyopadhyay P, Chowdhury NR, Chowdhury JR, Steer CJ. 1999. Correction of the UDP-glucuronosyltransferase gene defect in the Gunn rat model of Crigler-Najjar syndrome type I with a chimeric oligonucleotide. Proc Natl Acad Sci USA 96:10349-10354.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 10349-10354
-
-
Kren, B.T.1
Parashar, B.2
Bandyopadhyay, P.3
Chowdhury, N.R.4
Chowdhury, J.R.5
Steer, C.J.6
-
21
-
-
0036640365
-
Rad51p and Rad54p, but not Rad52p, elevate gene repair in Saccharomyces cerevisiae directed by modified single-stranded oligonucleotide vectors
-
Liu L, Cheng S, van Brabant AJ, Kmiec EB. 2002a. Rad51p and Rad54p, but not Rad52p, elevate gene repair in Saccharomyces cerevisiae directed by modified single-stranded oligonucleotide vectors. Nucleic Acids Res 30:2742-2750.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 2742-2750
-
-
Liu, L.1
Cheng, S.2
Van Brabant, A.J.3
Kmiec, E.B.4
-
22
-
-
0036097061
-
Strand bias in targeted gene repair is influenced by transcriptional activity
-
Liu L, Rice MC, Drury M, Cheng S, Gamper H, Kmiec EB. 2002b. Strand bias in targeted gene repair is influenced by transcriptional activity. Mol Cell Biol 22:3852-3863.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 3852-3863
-
-
Liu, L.1
Rice, M.C.2
Drury, M.3
Cheng, S.4
Gamper, H.5
Kmiec, E.B.6
-
23
-
-
2342574864
-
Genetic re-engineering of Saccharomyces cerevisiae RAD51 leads to a significant increase in the frequency of gene repair in vivo
-
Liu L, Maguire KK, Kmiec EB. 2004. Genetic re-engineering of Saccharomyces cerevisiae RAD51 leads to a significant increase in the frequency of gene repair in vivo. Nucleic Acids Res 32:2093-2101.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 2093-2101
-
-
Liu, L.1
Maguire, K.K.2
Kmiec, E.B.3
-
24
-
-
0141927821
-
Correction/mutation of acid alpha-D-glucosidase gene by modified single-stranded oligonucleotides: In vitro and in vivo studies
-
Lu IL, Lin CY, Lin SB, Chen ST, Yeh LY, Yang FY, Au LC. 2003. Correction/mutation of acid alpha-D-glucosidase gene by modified single-stranded oligonucleotides: In vitro and in vivo studies. Gene Ther 10:1910-1916.
-
(2003)
Gene Ther
, vol.10
, pp. 1910-1916
-
-
Lu, I.L.1
Lin, C.Y.2
Lin, S.B.3
Chen, S.T.4
Yeh, L.Y.5
Yang, F.Y.6
Au, L.C.7
-
25
-
-
0034090650
-
Mouse mutants from chemically mutagenized embryonic stem cells
-
Munroe RJ, Bergstrom RA, Zheng QY, Libby B. Smith R, John SW, Schimenti KJ, Browning VL, Schimenti JC. 2000. Mouse mutants from chemically mutagenized embryonic stem cells. Nat Genet 24:318-321.
-
(2000)
Nat Genet
, vol.24
, pp. 318-321
-
-
Munroe, R.J.1
Bergstrom, R.A.2
Zheng, Q.Y.3
Libby, B.4
Smith, R.5
John, S.W.6
Schimenti, K.J.7
Browning, V.L.8
Schimenti, J.C.9
-
26
-
-
0035895501
-
Functional annotation of mouse genome sequences
-
Nadeau JH, Balling R, Barsh G, Beier D, Brown SD, Bucan M. et al. 2001. Functional annotation of mouse genome sequences. Science 291:1251-1255.
-
(2001)
Science
, vol.291
, pp. 1251-1255
-
-
Nadeau, J.H.1
Balling, R.2
Barsh, G.3
Beier, D.4
Brown, S.D.5
Bucan, M.6
-
27
-
-
0034425410
-
A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse
-
Nolan PM, Peters J, Strivens M, Rogers D, Hagan J, Spurr N, Gray IC. et al. 2000. A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat Genet 25:440-443.
-
(2000)
Nat Genet
, vol.25
, pp. 440-443
-
-
Nolan, P.M.1
Peters, J.2
Strivens, M.3
Rogers, D.4
Hagan, J.5
Spurr, N.6
Gray, I.C.7
-
28
-
-
0027493872
-
Efficacy of tribromoethanol anesthesia in mice
-
Papaioannou VE, Fox JG. 1993. Efficacy of tribromoethanol anesthesia in mice. Lab Anim Sci 43:189-192.
-
(1993)
Lab Anim Sci
, vol.43
, pp. 189-192
-
-
Papaioannou, V.E.1
Fox, J.G.2
-
29
-
-
0036773706
-
Targeted nucleotide exchange in Saccharomyces cerevisiae directed by short oligonucleotides containing locked nucleic acids
-
Parekh-Olmedo H, Drury M, Kmiec EB. 2002. Targeted nucleotide exchange in Saccharomyces cerevisiae directed by short oligonucleotides containing locked nucleic acids. Chem Biol 9:1073-1084.
-
(2002)
Chem Biol
, vol.9
, pp. 1073-1084
-
-
Parekh-Olmedo, H.1
Drury, M.2
Kmiec, E.B.3
-
30
-
-
1342311411
-
The effect of hydroxyurea and trichostatin A on targeted nucleotide exchange in yeast and mammalian cells
-
Parekh-Olmedo H, Engstrom JU, Kmiec EB. 2003. The effect of hydroxyurea and trichostatin A on targeted nucleotide exchange in yeast and mammalian cells. Ann NY Acad Sci 1002:43-55.
-
(2003)
Ann NY Acad Sci
, vol.1002
, pp. 43-55
-
-
Parekh-Olmedo, H.1
Engstrom, J.U.2
Kmiec, E.B.3
-
31
-
-
0037265663
-
Oligonucleotide-directed single-base DNA alterations in mouse embryonic stem cells
-
Pierce EA, Liu Q, Igoucheva O, Omarrudin R, Ma H, Diamond SL, Yoon K. 2003. Oligonucleotide-directed single-base DNA alterations in mouse embryonic stem cells. Gene Ther 10:24-33.
-
(2003)
Gene Ther
, vol.10
, pp. 24-33
-
-
Pierce, E.A.1
Liu, Q.2
Igoucheva, O.3
Omarrudin, R.4
Ma, H.5
Diamond, S.L.6
Yoon, K.7
-
32
-
-
13644267927
-
Unmodified oligodeoxynucleotides require single-strandedness to induce targeted repair of a chromosomal EGFP gene
-
Radecke F, Radecke S, Schwarz K. 2004. Unmodified oligodeoxynucleotides require single-strandedness to induce targeted repair of a chromosomal EGFP gene. J Gene Med 6:1257-1271.
-
(2004)
J Gene Med
, vol.6
, pp. 1257-1271
-
-
Radecke, F.1
Radecke, S.2
Schwarz, K.3
-
34
-
-
0037441645
-
Rapid generation of inducible mouse mutants
-
Seibler J, Zevnik B, Kuter-Luks B, Andreas S, Kern H, Hennek T, Rode A, Heimann C, Faust N, Kauselmann G, Schoor M, Jaenisch R, Rajewsky K, Kuhn R, Schwenk F. 2003. Rapid generation of inducible mouse mutants. Nucleic Acids Res 31:e12.
-
(2003)
Nucleic Acids Res
, vol.31
-
-
Seibler, J.1
Zevnik, B.2
Kuter-Luks, B.3
Andreas, S.4
Kern, H.5
Hennek, T.6
Rode, A.7
Heimann, C.8
Faust, N.9
Kauselmann, G.10
Schoor, M.11
Jaenisch, R.12
Rajewsky, K.13
Kuhn, R.14
Schwenk, F.15
-
35
-
-
0035918314
-
Gene correction of the apolipoprotein (Apo) E2 phenotype to wild-type ApoE3 by in situ chimeraplasty
-
Tagalakis AD, Graham IR, Riddell DR, Dickson JG, Owen JS. 2001. Gene correction of the apolipoprotein (Apo) E2 phenotype to wild-type ApoE3 by in situ chimeraplasty. J Biol Chem 276:13226-13230.
-
(2001)
J Biol Chem
, vol.276
, pp. 13226-13230
-
-
Tagalakis, A.D.1
Graham, I.R.2
Riddell, D.R.3
Dickson, J.G.4
Owen, J.S.5
-
36
-
-
0037073475
-
The strange case of chimeraplasty
-
Taubes G. 2002. The strange case of chimeraplasty. Science 298:2116-2120.
-
(2002)
Science
, vol.298
, pp. 2116-2120
-
-
Taubes, G.1
-
37
-
-
0038023191
-
High-throughput engineering of the mouse genome coupled with high-resolution expression analysis
-
Valenzuela DM, Murphy AJ, Frendewey D, Gale NW, Economides AN, Auerbach W, Poueymirou WT, Adams NC, Rojas J, Yasenchak J, Chernomorsky R, Boucher M, Elsasser AL, Esau L, Zheng J, Griffiths JA, Wang X, Su H, Xue Y, Dominguez MG, Noguera I, Torres R, Macdonald LE, Stewart AF, DeChiara TM, Yancopoulos GD. 2003. High-throughput engineering of the mouse genome coupled with high-resolution expression analysis. Nat Biotechnol 21:652-659.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 652-659
-
-
Valenzuela, D.M.1
Murphy, A.J.2
Frendewey, D.3
Gale, N.W.4
Economides, A.N.5
Auerbach, W.6
Poueymirou, W.T.7
Adams, N.C.8
Rojas, J.9
Yasenchak, J.10
Chernomorsky, R.11
Boucher, M.12
Elsasser, A.L.13
Esau, L.14
Zheng, J.15
Griffiths, J.A.16
Wang, X.17
Su, H.18
Xue, Y.19
Dominguez, M.G.20
Noguera, I.21
Torres, R.22
Macdonald, L.E.23
Stewart, A.F.24
DeChiara, T.M.25
Yancopoulos, G.D.26
more..
-
38
-
-
0035066680
-
Persistent failures in gene repair
-
van der Steege G, Schuilenga-Hut PH, Buys CH, Scheffer H, Pas HH, Jonkman MF. 2001. Persistent failures in gene repair. Nat Biotechnol 19:305-306.
-
(2001)
Nat Biotechnol
, vol.19
, pp. 305-306
-
-
Van Der Steege, G.1
Schuilenga-Hut, P.H.2
Buys, C.H.3
Scheffer, H.4
Pas, H.H.5
Jonkman, M.F.6
-
39
-
-
0033988749
-
Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells
-
Wiles MV, Vauti F, Otte J, Fuchtbauer EM, Ruiz P, Fuchtbauer A, Arnold HH, Lehrach H, Metz T, von Melchner H, Wurst W. 2000. Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells. Nat Genet 24:13-14.
-
(2000)
Nat Genet
, vol.24
, pp. 13-14
-
-
Wiles, M.V.1
Vauti, F.2
Otte, J.3
Fuchtbauer, E.M.4
Ruiz, P.5
Fuchtbauer, A.6
Arnold, H.H.7
Lehrach, H.8
Metz, T.9
Von Melchner, H.10
Wurst, W.11
-
40
-
-
0032499252
-
Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells
-
Zambrowicz BP, Friedrich GA, Buxton EC, Lilleberg SL, Person C, Sands AT. 1998. Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells. Nature 392:608-611.
-
(1998)
Nature
, vol.392
, pp. 608-611
-
-
Zambrowicz, B.P.1
Friedrich, G.A.2
Buxton, E.C.3
Lilleberg, S.L.4
Person, C.5
Sands, A.T.6
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