Molecular profiles of BRCA1-mutated and matched sporadic breast tumours: Relation with clinico-pathological features

British Journal of Cancer

Volumn 85, Issue 4, 2001, Pages 538-545

  Berns, E M J J ^a   Van Staveren, I L ^a   Verhoog, L ^a,b   Ouweland, A M ^b   Gelder, M ^a   Meijers Heijboer, H ^b   Portengen, H ^a   Foekens, J A ^a   Dorssers, L C J ^b   Klijn, J G M ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

BRCA1; Breast cancer; CDNA array; Clinical features; Molecular profiles

Indexed keywords

BRCA1 PROTEIN;

ADULT; AGED; ALGORITHM; ARTICLE; B LYMPHOBLAST; BREAST CANCER; CANCER CELL CULTURE; CANCER SUSCEPTIBILITY; CELL ADHESION; CELL MIGRATION; COMPUTER PROGRAM; CONTROLLED STUDY; FAMILY HISTORY; FEMALE; FIBROBLAST CULTURE; GENE CLUSTER; GENE DELETION; GENE EXPRESSION; GENE INSERTION; GENE MUTATION; GENETIC SUSCEPTIBILITY; GERM LINE; HEREDITY; HUMAN; HUMAN CELL; HUMAN TISSUE; ONCOGENE; OVARY CELL; PILOT STUDY; PRIORITY JOURNAL;

BREAST NEOPLASMS; CELL ADHESION; CELL MOVEMENT; DNA MUTATIONAL ANALYSIS; DNA, COMPLEMENTARY; FEMALE; GENE EXPRESSION REGULATION; GENES, BRCA1; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RNA;

EID: 17944376805     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.2001.1937     Document Type: Article

References (29)

1. Epidemiology, prevention, and early detection of breast cancer
2. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
3. Purification of mouse immunoglobulin heavychain messenger RNAs from total myeloma tumor RNA
4. TP53 and MYC gene alterations independently predict poor prognosis in breast cancer patients
5. Mutations in residues of TP53 that directly contact DNA predict poor outcome in human primary breast cancer
6. Epidermal growth factor-induced nuclear factor kappa B activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells
7. Molecular classification of cutaneous malignant melanoma by gene expression profiling
8. Role of the tumor suppressor gene Brca 1 in genetic stability and mammary gland tumor formation
9. Cluster analysis and display of genome-wide expression patterns
10. Prognostic value of estrogen and progesterone receptors measured by enzyme immunoassays in human breast tumor cytosols
11. Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
12. Epidermal growth factor receptor and other oncogenes as prognostic markers
13. The clinical significance of epidermal growth factor receptor (EGF-R) in human breast cancer: A review on 5232 patients
14. Altered expression of p53 and its regulated proteins in phyllodes tumours of the breast
15. Multifactodal analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations
16. Genetic and hormonal risk factors in breast cancer
17. Cytokeratin 5/6 immunohistochemistry assists the differential diagnosis of atypical proliferations of the breast
18. Prevalence of BRCA1 in a hospital-based population of Dutch breast cancer patients
19. BRCA1: A review of structure and putative functions
20. A high proportion of novel mutations in BRCA 1 with strong founder effects among Dutch and Belgian hereditary breast and ovarian cancer families
21. Distinctive gene expression patterns in human mammary epithelial cells and breast cancers
22. Molecular portraits of human breast tumours
23. BRCA1 genomic deletions are major founder mutations in Dutch breast cancer patients
24. Breast carcinomas arising in carriers of mutations in BRCA1 or BRCA2: Are they prognostically different?
25. Systematic variation in gene expression patterns in human cancer cell lines
26. In viva gene expression profile analysis of human breast cancer progression
27. Characterization of a breast cancer cell line derived from a germ-line BRCA1 mutation carrier
28. Insights into the functions of BRCA1 and BRCA2
29. Localization of human BRCA1 and its loss in highgrade, non-inherited breast carcinomas