Analysis of insulin-stimulated insulin receptor activation and glucose transport in cultured skeletal muscle cells from obese subjects

Metabolism: Clinical and Experimental

Volumn 54, Issue 5, 2005, Pages 598-603

  Pender, Celia ^a   Goldfine, Ira D ^a   Kulp, Jennifer L ^a   Tanner, Charles J ^b   Maddux, Betty A ^a   MacDonald, Kenneth G ^c   Houmard, Joseph A ^b   Youngren, Jack F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b EAST CAROLINA UNIVERSITY   (United States)

^c EAST CAROLINA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 4; INSULIN; INSULIN RECEPTOR; PROTEIN; PROTEIN KINASE B; PROTEIN PC 1; UNCLASSIFIED DRUG;

ADULT; ARTICLE; AUTOPHOSPHORYLATION; CELL CULTURE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FEMALE; GLUCOSE TRANSPORT; HORMONE ACTION; HUMAN; HUMAN CELL; HUMAN TISSUE; INSULIN RESISTANCE; MALE; MUSCLE CELL; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL; PROTEIN CONTENT; RECEPTOR DENSITY; RECEPTOR INTRINSIC ACTIVITY; SKELETAL MUSCLE;

EID: 17844372969     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2004.11.018     Document Type: Article

References (21)

1. C.R. Kahn Banting lecture. Insulin action, diabetogenes, and the cause of type II diabetes Diabetes 43 1994 1066 1084
2. B.C. Martin, J.H. Warram, and A.S. Krolewski Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study [see comments] Lancet 340 1992 925 929
3. L. Mykkanen, S.M. Haffner, and T. Ronnemaa Low insulin sensitivity is associated with clustering of cardiovascular disease risk factors Am. J. Epidemiol. 146 1997 315 321
4. J.O. Clausen, K. Borch-Johnsen, and H. Ibsen Insulin sensitivity index, acute insulin response, and glucose effectiveness in a population-based sample of 380 young healthy Caucasians. Analysis of the impact of gender, body fat, physical fitness, and life-style factors J. Clin. Invest. 98 1996 1195 1209
5. R.A. DeFronzo Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM Diabetes 37 1988 667 687
6. G.L. Dohm, E.B. Tapscott, and W.J. Pories An in vitro human muscle preparation suitable for metabolic studies. Decreased insulin stimulation of glucose transport in muscle from morbidly obese and diabetic subjects J. Clin. Invest. 82 1988 486 494
7. T.P. Ciaraldi, L. Abrams, and S. Nikoulina Glucose transport in cultured human skeletal muscle cells. Regulation by insulin and glucose in nondiabetic and non-insulin-dependent diabetes mellitus subjects J. Clin. Invest. 96 1995 2820 2827
8. R.R. Henry, L. Abrams, and S. Nikoulina Insulin action and glucose metabolism in nondiabetic control and NIDDM subjects. Comparison using human skeletal muscle cell cultures Diabetes 44 1995 936 946
9. M. Gaster, I. Petersen, and K. Hojlund The diabetic phenotype is conserved in myotubes established from diabetic subjects: evidence for primary defects in glucose transport and glycogen synthase activity Diabetes 51 2002 921 927
10. R.R. Henry, T.P. Ciaraldi, and L. Abrams-Carter Glycogen synthase activity is reduced in cultured skeletal muscle cells of non-insulin-dependent diabetes mellitus subjects. Biochemical and molecular mechanisms J. Clin. Invest. 98 1996 1231 1236
11. J.T. Brozinick Jr., B.R. Roberts, and G.L. Dohm Defective signaling through Akt-2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle: potential role in insulin resistance Diabetes 52 2003 935 941
12. D.R. Matthews, J.P. Hosker, and A.S. Rudenski Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man Diabetologia 28 1985 412 419
13. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248 254
14. D.B. Thompson, R. Pratley, and V. Ossowski Human primary myoblast cell cultures from non-diabetic insulin resistant subjects retain defects in insulin action J. Clin. Invest. 98 1996 2346 2350
15. J.F. Youngren, I.D. Goldfine, and R.E. Pratley Insulin receptor autophosphorylation in cultured myoblasts correlates to glucose disposal in Pima Indians Am. J. Physiol. 276 1999 E990 E994
16. L. Frittitta, J.F. Youngren, and P. Sbraccia Increased adipose tissue PC-1 protein content, but not tumour necrosis factor-alpha gene expression, is associated with a reduction of both whole body insulin sensitivity and insulin receptor tyrosine-kinase activity Diabetologia 40 1997 282 289
17. R.J. Barnard, and J.F. Youngren Regulation of glucose transport in skeletal muscle FASEB J. 6 1992 3238 3244
18. D.M. Mott, C. Hoyt, and R. Caspari Palmitate oxidation rate and action on glycogen synthase in myoblasts from insulin-resistant subjects Am. J. Physiol. Endocrinol. Metab. 279 2000 E561 E569
19. S. Jackson, S.M. Bagstaff, and S. Lynn Decreased insulin responsiveness of glucose uptake in cultured human skeletal muscle cells from insulin-resistant nondiabetic relatives of type 2 diabetic families Diabetes 49 2000 1169 1177
20. J. Krutzfeldt, C. Kausch, and A. Volk Insulin signaling and action in cultured skeletal muscle cells from lean healthy humans with high and low insulin sensitivity Diabetes 49 2000 992 998
21. P. Vollenweider, B. Menard, and P. Nicod Insulin resistance, defective insulin receptor substrate 2-associated phosphatidylinositol-3′ kinase activation, and impaired atypical protein kinase C (zeta/lambda) activation in myotubes from obese patients with impaired glucose tolerance Diabetes 51 2002 1052 1059