The ATM gene in the pathogenesis of mantle-cell lymphoma

Annals of Oncology

Volumn 11, Issue SUPPL. 1, 2000, Pages

  Stilgenbauer, S ^d   Schaffner, C ^a   Winkler, D ^d   Ott, G ^d   Leupolt, E ^d   Bentz, M ^d   Moller P ^d   Muller Hermelink H K ^d   James, M R ^b   Lichter, P ^a   Dohner H ^c  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF ULM   (Germany)

^d NONE

Author keywords

11q22 q23 deletion; Ataxia telangiectasia; ATM; Mantle cell lymphoma; Tumor suppressor gene

Indexed keywords

CARCINOGENESIS; CHROMOSOME 11Q; CHROMOSOME ANALYSIS; CONFERENCE PAPER; CONTROLLED STUDY; GENE DELETION; HUMAN; HUMAN TISSUE; INCIDENCE; MANTLE CELL LYMPHOMA; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

EID: 17744419841     PISSN: 09237534     EISSN: None     Source Type: Journal    
DOI: 10.1093/annonc/11.suppl_1.S127     Document Type: Conference Paper

References (40)

1. Harris NL, Jaffe ES, Stein H et al. A Revised European-American Classification of Lymphoid Neoplasms: A proposal from the International Lymphoma Study Group. Blood 1994; 84: 1361-92.
2. Weisenburger DD, Armitage JO. Mantle-cell lymphoma - an entity comes of age. Blood 1996; 87: 4483-94.
3. Leroux D, Le Marc'hadour F, Gressin R et al. Non-Hodgkin's lymphomas with t(11;14)(q13;q32): A subset of mantle zone/intermediate lymphocytic lymphomas? Br J Haematol 1991; 77: 346-53.
4. Vandenberghe E, de Wolf-Peeters C, Wlodarska I et al. Chromosome 11q rearrangements in B non-Hodgkin's lymphoma. Br J Haematol 1992; 81: 212-7.
5. Tsujimoto Y, Yunis J, Onorato-Showe L et al. Molecular cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the t(11;14) chromosome translocation. Science 1984; 224: 1403-6.
6. Rosenberg CL, Wong E, Petty EM et al. PRAD1, a candidate BCL-1 oncogene: Mapping and expression in centrocytic lymphoma. Proc Natl Acad Sci USA 1991; 88: 9636-964.
7. Williams ME, Meeker TC, Swerdlow SH. Rearrangement of the chromosome 11 BCL-1 locus in centrocytic lymphoma: Analysis with multiple breakpoint probes. Blood 1991; 78: 493-8.
8. Rimokh R, Berger F, Delsol G et al. Rearrangement and overexpression of the BCL-1/PRAD-1 gene in intermediate lymphocytic lymphomas and t(11q13)-bearing leukemias. Blood 1993; 81: 3063-7.
9. Bosch F, Jares P, Campo E et al. PRAD-1/Cyclin D1 overexpression in chronic lymphoproliferative disorders: A highly specific marker of mantle-cell lymphoma. Blood 1994; 84: 2726-32.
10. Ott MM, Helbing A, Ott G et al. BCL-1 gene rearrangement and cyclin D1 protein expression in mantle-cell lymphoma. J Pathol 1996; 179: 238-42.
11. Hinds PW, Dowdy SF, Eaton EN et al. Function of a human cyclin gene as an oncogene. Proc Natl Acad Sci USA 1994; 91: 709-13.
12. Bodrug SE, Warner BJ, Bath ML et al. Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene. EMBO J 1994; 13: 2124-30.
13. Lovec H, Grzeschiczek A, Kowalski MB, Möröy T. Cyclin D1/BCL-1 cooperates with myc genes in the generation of B-cell lymphoma in transgenic mice. EMBO J 1994; 13: 3487-95.
14. Louie DC, Offit K, Jaslow R et al. p53 overexpression as a marker of poor prognosis in mantle-cell lymphomas with t(11;14)(q13;q32). Blood 1995; 86: 2892-9.
15. Greiner TC, Moynihan MJ, Chan WC et al. p53 mutations in mantle-cell lymphoma are associated with variant cytology and predict a poor prognosis. Blood 1996; 87: 4302-10.
16. Hernandez L, Fest T, Cazorla M et al. p53 gene mutations and protein overexpression are associated with aggressive variants of mantle-cell lymphomas. Blood 1996; 87: 3351-9.
17. Dreyling MH, Bullinger L, Ott G et al. Alterations of the cyclin D1/p16-pRB pathway in mantle-cell lymphoma. Cancer Res 1997; 57: 4608-14.
18. Ott G, Kalla J, Ott MM et al. Blastoid variants of mantle-cell lymphoma: Frequent BCL-1 rearrangements at the major translocation cluster region and tetraploid chromosome clones. Blood 1997; 89: 1421-9.
19. wafl genes are associated with aggressive variants of mantle-cell lymphomas. Blood 1997; 89: 272-80.
20. Johansson B, Mertens F, Mitelman F. Cytogenetic evolution patterns in non-Hodgkin's lymphoma. Blood 1995; 86: 3905-14.
21. Nowotny H, Karlic H, Gruner H et al. Cytogenetic findings in 175 patients indicate that items of the Kiel Classification should not be disregarded in the R.E.A.L. Classification of lymphoid neoplasms. Ann Hematol 1996; 72: 291-301.
22. Argatoff LH, Connors JM, Klasa RJ et al. Mantle-cell lymphoma: A clinicopathologic study of 80 cases. Blood 1997; 89: 2067-78.
23. Monni O, Oinonen R, Elonen E et al. Gain of 3q and deletion of 11q22 are frequent aberrations in mantle-cell lymphoma. Genes Chromosom Cancer 1998; 21: 298-307.
24. Stilgenbauer S, Liebisch P, James MR et al. Molecular cytogenetic delineation of a novel critical genomic region in chromosome bands 11q22.3-q23.1 in lymphoproliferative disorders. Proc Natl Acad Sci USA 1996; 93: 11837-41.
25. Lichter P, Bentz M, Joos S. Detection of chromosomal aberrations by means of molecular cytogenetics: Painting of chromosomes and chromosomal subregions and comparative genomic hybridization. Methods Enzymol 1995; 254: 334-59.
26. Döhner H, Stilgenbauer S, James MR et al. 11q deletions identify a new subset of B-cell chronic lymphocytic leukemia characterized by extensive nodal involvement and inferior prognosis. Blood 1997; 89: 2516-22.
27. James MR, Richard CW III, Schott JJ et al. A radiation hybrid map of 506 STS markers spanning human chromosome 11. Nature Genet 1994; 6: 70-4.
28. Stilgenbauer S, Schaffner C, Litterst A et al. Biallelic mutations of the ATM gene in T-prolymphocytic leukemia. Nature Med 1997; 3: 1155-9.
29. Vorechovsky I, Luo L, Dyer MJ et al. Clustering of missense mutations in the ataxia-telangiectasia gene in a sporadic T-cell leukaemia. Nature Genet 1997; 17: 96-9.
30. Ioannou PA, Amemiya CT, Garnes J et al. A new bacteriophage P1-derived vector for the propagation of large human DNA fragments. Nature Genet 1994; 6: 84-9.
31. Savitsky K, Bar-Shira A, Gilad S et al. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 1995; 268: 1749-53.
32. Schaffner C, Stilgenbauer S, Rappold GA et al. Somatic ATM mutations indicate a pathogenic role of ATM in B-cell chronic lymphocytic leukemia. Blood 1999; 94: 748-53.
33. Stilgenbauer S, Nickolenko J, Wilhelm J et al. Expressed sequences as candidates for a novel tumor suppressor gene at band 13q14 in B-cell chronic lymphocytic leukemia and mantle-cell lymphoma. Oncogene 1998; 16: 1891-7.
34. Monni O, Zhu Y, Franssila K et al. Molecular characterization of deletion at 11q22.1-23.3 in mantle-cell lymphoma. Br J Haematol 1999; 104: 665-71.
35. Stoppa-Lyonnet D, Soulier J, Lauge A et al. Inactivation of the ATM gene in T-prolymphocytic leukemia. Blood 1998; 91: 3920-6.
36. Starostik P, Manshouri T, O'Brien S et al. Deficiency of the ATM protein defines an aggressive subgroup of B-cell chronic lymphocytic leukemia. Cancer Res 1998; 58: 4552-7.
37. Bullrich F, Rasio D, Kitada S et al. Mutations in B-cell chronic lymphocytic leukemia. Cancer Res 1999; 59: 24-7.
38. Stankovic T, Weber P, Stewart G et al. Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia. Lancet 1999; 353: 26-9.
39. Rotman G, Shiloh Y. ATM: From gene to function. Hum Mol Genet 1998; 7: 1555-63.
40. Taylor AMR, Metcalfe JA, Thick J, Mak YF. Leukemia and lymphoma in ataxia telangiectasia. Blood 1996; 87: 423-38.