Development of humanized antibodies as cancer therapeutics

Methods

Volumn 36, Issue 1, 2005, Pages 84-95

  Qu, Zhengxing ^a   Griffiths, Gary L ^a   Wegener, William A ^a   Chang, Chien Hsing ^a   Govindan, Serengulam V ^a   Horak, Ivan D ^a   Hansen, Hans J ^a   Goldenberg, David M ^b  

^a IMMUNOMEDICS INC   (United States)

^b CENTER FOR MOLECULAR MEDICINE AND IMMUNOLOGY   (United States)

Author keywords

Cancer therapy; CDR grafting; Epratuzumab; Immunoconjugates; Labetuzumab; Monoclonal antibody

Indexed keywords

ALEMTUZUMAB; BEVACIZUMAB; CARCINOEMBRYONIC ANTIBODY; CETUXIMAB; CHIMERIC ANTIBODY; EPRATUZUMAB; GEMTUZUMAB OZOGAMICIN; IBRITUMOMAB TIUXETAN; LABETUZUMAB; RADIOACTIVE IODINE; RITUXIMAB; TOSITUMOMAB I 131; TRASTUZUMAB; UNCLASSIFIED DRUG; YTTRIUM 90;

ACUTE GRANULOCYTIC LEUKEMIA; ANTIBODY ENGINEERING; ARTICLE; B CELL LEUKEMIA; B CELL LYMPHOMA; BLOOD TOXICITY; BREAST CANCER; CANCER THERAPY; CLINICAL TRIAL; COLORECTAL CANCER; DRUG DESIGN; DRUG SAFETY; DRUG TOLERABILITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPRESSION VECTOR; GENE AMPLIFICATION; GENE SEQUENCE; GENE SYNTHESIS; HEAVY CHAIN; HUMAN; LIGHT CHAIN; METASTASIS; METHODOLOGY; MOLECULAR CLONING; NONHODGKIN LYMPHOMA; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; SINGLE DRUG DOSE; SJOEGREN SYNDROME; SYSTEMIC LUPUS ERYTHEMATOSUS;

EID: 17644386490     PISSN: 10462023     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymeth.2005.01.008     Document Type: Article

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