Potential role of molecular mimicry between Helicobacter pylori lipopolysaccharide and host Lewis blood group antigens in autoimmunity

Infection and Immunity

Volumn 64, Issue 6, 1996, Pages 2031-2040

  Appelmelk, Ben J ^a,i   Simoons Smit, Ina ^a   Negrini, Riccardo ^b   Moran, Anthony P ^c   Aspinall, Gerald O ^d   Forte, John G ^e   De Vries, Theodora ^a   Quan, Hu ^a   Verboom, Theo ^a   Maaskant, Janneke J ^a   Ghiara, Paolo ^f   Kuipers, Ernst J ^a   Bloemena, Elisabeth ^a   Tadema, Thea M ^a   Townsend, Reid R ^g   Tyagarajan, Kamala ^e   Crothers Jr , Jim M ^e   Monteiro, Mario A ^d   Savio, Antonella ^h   De Graaff, Johannes ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b SPEDALI CIVILI   (Italy)

^c NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^d YORK UNIVERSITY   (Canada)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f Immunobiol Res Institute of Siena   (Italy)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h S Orsola Hospital   (Italy)

ⁱ VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; BLOOD GROUP ANTIGEN; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNITY; BACTERIUM ISOLATION; BLOOD GROUP LEWIS SYSTEM; DUODENUM ULCER; GASTRITIS; HELICOBACTER PYLORI; HUMAN; HUMAN TISSUE; MOUSE; MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA; NONHUMAN; PEPTIC ULCER; PRIORITY JOURNAL; STOMACH ADENOCARCINOMA;

EID: 9344248024     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.6.2031-2040.1996     Document Type: Article

References (44)

1. Aspinall, G. O., A. G. McDonald, and H. Pang. 1994. 1996. Lipopolysaccharides of Campylobacter jejuni serotype O19; structures of the O-antigen chains from the serostrain and two bacterial isolates from patients with the Guillain-Barre syndrome. Biochemistry 33:250-255.
2. Aspinall, G. O., and M. A. Monteiro. 1996. Lipopolysaccharides of Helicobacter pylori strains P466 and MO19: structures of the O antigen and core oligosaccharide strains. Biochemistry 35:2498-2504.
3. Aspinall, G. O., M. A. Monteiro, H. Pang, E. J. Walsh, and A. P. Moran. 1994. O antigen chains in the lipopolysaccharide of Helicobacter pylori NCTC 11637. Carbohydr. Lett. 1:151-156.
4. Aspinall, G. O., M. O. Monteiro, H. Pang, E. J. Walsh, and A. P. Moran. 1996. Lipopolysaccharide of the Helicobacter pylori type strain NCTC 11637 (ATCC 43504): structure of the O antigen and core oligosaccharide regions. Biochemistry 35:2489-2497.
5. +-adenosine triphosphatase, the proton pump of the stomach. Gastroenterology 96:1434-1438.
6. 3 Mr membrane glycoprotein. J. Cell Sci. 95:563-576.
7. Chan, N. W. C., K. Stangier, R. Sherburne, D. E. Taylor, Y. Zhang, N. J. Dovichi, and M. M. Palcic. 1995. The biosynthesis of Lewis x in Helicobacter pylori. Glycobiology 5:683-688.
8. +-ATPase using an inhibitory monoclonal antibody. Am. J. Physiol. 265:C1562-C1570.
9. +-ATPase in the rabbit parietal cell. Am. J. Physiol. 269:G883-891.
10. de Vries, T., C. A. Srnka, M. M. Palcic, S. J. Swiedler, D. H. van den Eijnden, and B. A. Macher. 1995. Acceptor specificity of different length constructs of human alpha 1,3/4-fucosyltransferases. Replacement of the stem region and the transmembrane domain of fucosyltransferase V by protein A results in an enzyme with GDP-fucose hydrolysing activity. J. Biol. Chem. 270:8712-8722.
11. Faller, G., H. Steininger, and T. Kirchner. 1995. Antigastric autoantibodies in Helicobacter pylori gastritis. Prevalence, in situ binding sites and positive correlation with gastric atrophy and hypergastrinemia, abstr. 132. In Abstracts of the 7th International Workshop on Gastroduodenal Pathology and Helicobacter pylori. Gut, vol. 37. suppl. 1.
12. Gleeson, P. A. 1994. Glycoconjugates in autoimmunity. Biochim. Biophys. Acta 1197:237-255.
13. Goldkorn, I., P. A. Gleeson, and B.-H. Toh. 1989. Gastric parietal cell antigens of 60-90, 92, and 100-120 kDa associated with autoimmune gastritis and pernicious anaemia. Role of N-glycans in the structure and antigenicity of the 60-90-kDa component. J. Biol. Chem. 264:18768-18774.
14. Greiner, A., A. Marx, J. Heesemann, J. Leebmann, B. Schmausser, and H. K. Müller-Hermelink. 1994. Idiotype identity in a MALT-type lymphoma and B cells in Helicobacter pylori chronic gastritis. Lab. Invest. 70:572-578.
15. Gueant, J. L., I. Kouvonen, J. C. Michalski, C. Masson, R. Grasbeck, and J. P. Nicholas. 1985. Purification of human intrinsic factor using high-performance ion-exchange chromatography as the final step. FEBS Lett. 184: 14-19.
16. International Agency for Research on Cancer. 1994. Schistosomes, liver flukes and Helicobacter pylori. IARC Monogr. Eval. Carcinog. Risks Hum., vol. 61.
17. Isaacson, P. G., and J. Spencer. 1993. Malignant lymphoma and autoimmune disease. Histopathology 22:509-510.
18. +-adenosine triphosphatase of the stomach. J. Clin. Invest. 81:475-479.
19. Kobayashi, K., J. Sakamoto, T. Kito, Y. Yamamura, T. Koshikawa, M. Fujita, T. Watanabe, and H. Nakazato. 1993. Lewis blood group-related antigen expression in normal gastric epithelium, intestinal metaplasia, gastric adenoma, and gastric carcinoma. Am. J. Gastroenterol. 88:919-924.
20. Kuipers, E. J., J. C. Thijs, and H. P. M. Festen. 1995. Helicobacter and peptic ulcer disease. Aliment. Pharmacol. Ther. 9(Suppl. 2):59-69.
21. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227:680-685.
22. Ma, J.-Y., K. Borch, and S. Mårdh. 1994. Human gastric H,K-adenosine triphosphatase β-subunit is a major autoantigen in atrophic corpus gastritis. Expression of the recombinart human glycoprotein in insect cells. Scand. J. Gastroenterol. 29:790-794.
23. Ma, J.-Y., K. Borch, S. E. Sjöstrand, L. Janzon, and S. Mårdh. 1994. Positive correlation between H,K-adenosine triphosphatase autoantibodies and Helicobacter pylori antibodies in patients with pernicious anaemia. Scand. J. Gastroenterol. 29:961-965.
24. Marchetta, M., B. Arico, D. Burroni, N. Figura, R. Rappuoli, and P. Ghiara. 1995. Development of a mouse model of Helicobacter pylori infection that mimics human disease. Science 267:1655-1658.
25. Mills, S. D., L. A. Kurjanczyk, and J. L. Penner. 1992. Antigenicity of Helicobacler pylori lipopolysaccharides. J. Clin. Microbiol. 30:3175-3180.
26. Moran, A. P., I. M. Helander, and T. U. Kosunen. 1992. Compositional analysis of Helicobacler pylori rough-form lipopolysaccharides. J. Bacteriol. 174:1370-1377.
27. Naparstek, Y., and P. H. Plotz. 1993. The role of autoantibodies in autoimmune disease. Annu. Rev. Immunol. 11:79-104.
28. Negrini, R., L. Lisato, I. Zanella, S. Cavazzini, S. Gullini, V. Villanacci, C. Poiesi, A. Albertini, and S. Ghielmi. 1991. Helicobacler pylori infection induces antibodies cross-reacting with human gastric mucosa. Gastroenterology 101:437-445.
29. Negrini, R., A. Savio, M. Graffeo, F. Rolfi, and S. Ghielmi. 1993. Auto-antibodies and gastric Helicobacler pylori infection: does autoimmunity affect progression to atrophic gastritis? Eur. J. Gastroenterol. Hepatol. 5(Suppl. 2):S27-S29.
30. Negrini, R., I. Zanelli, A. Savio, C. Poiesi, R. Verardi, S. Ghielmi, A. Albertini, O. Sangaletti, M. Lazzaroni, and G. Bianchi Porro. 1992. Serodiagnosis of Helicobacter pylori-associated gastritis with a monoclonal antibody competitive enzyme-linked immunosorbent assay. Scand. J. Gastroenterol. 27: 599-605.
31. Nyame, K., J. B. Pilcher, V. Tsang, and R. D. Cummings. 1995. Infection of monkeys and humans with the helminthic parasite Schistosoma mansoni induces autoimmunity to the Lewis x antigen, abstr. S25. In Abstracts of the 8th International Symposium on Glycoconjugates. Glycoconj. J. 12: 531.
32. +-ATPase. Biochem. Biophys. Acta 1037:360-372.
33. Parsonnet, J., S. Hansen, L. Rodriguez, A. B. Gelb, R. A. Warnke, E. Jellum, N. Orentreich, J. H. Vogelman, and G. D. Friedman. 1994. Helicobacler pylori infection and gastric lymphoma. N. Engl. J. Med. 330:1267-1271.
34. Sarnesto, A., T. Köhlin, O. Hindsgaul, J. Thurin, and M. Blaszczyk-Thurin. 1992. Purification of the secretor-type β-galactoside α1-2 fucosyltransferase from human serum. J. Biol. Chem. 267:2737-2744.
35. Sherburne, R., and D. E. Taylor. 1995. Helicobacter pylori expresses a complex surface carbohydrate, Lewis x. Infect. Immun. 63:4564-4568.
36. Simoons-Smit, I. M., B. J. Appelmelk, T. Verboom, R. Negrini, J. L. Penner, G. O. Aspinall, A. P. Moran, S. Fei-fei, S. Bi-shan, W. Rudnica, and J. de Graaff. Typing of Helicobacter pylori with monoclonal antibodies against lewis antigens in lipopolysaccharide. Submitted for publication.
37. Stöckl, J., O. Majdic, A. Rosenkranz, E. Fiebiger, B. Kniep, H. Stockinger, and W. Knapp. 1993. Monoclonal antibodies to the carbohydrate structure Lewis x stimulate the adhesive activity of leucocyte integrin CD11b/CD18 (CR3, Mac-1, α(m)β2) on human granulocytes. J. Leukocyte Biol. 53:541-549.
38. + - ATPase (proton pump). Proc. Natl. Acad. Sci. USA 87:6418-6422.
39. Tsai, C. M., and C. E. Frasch. 1982. A sensitive silver stain for detecting lipopolysaccharides in polyacrylamide gels. Anal. Biochem. 119:115-119.
40. Van Dam, G. J., A. A. Bergwerff, J. E. Thomas-Oates, J. P. Rotmans, J. P. Kamerling, J. F. Vliegenthart, and A. M. Deelder. 1994. The immunologically reactive O-linked polysaccharide chains derived from circulating cathodic antigen isolated from human blood fluke Schistosoma mansoni have Lewis x as repeating unit. Eur. J. Biochem. 225:467-482.
41. van Dam, G. J., F. H. J. Claas, M. Yazdanbakhsh, Y. C. M. Kruize, A. C. I. van Keulen, S. T. M. Falcao Ferreira, J. P. Rotmans, and A. M. Deelder. 1995. Schistosoma mansoni excretory antigen CCA shares carbohydrate epitopes with human granulocytes and evokes host antibodies mediating complement-dependent lysis of granulocytes, p. 174-187. In G. J. van Dam (ed.), Circulating gut-associated antigens of Schistosoma mansoni: biological, immunological and molecular aspects. Thesis, University of Leiden, Leiden, The Netherlands.
42. + T-cell subsets. Proc. Natl. Acad. Sci. USA 91:18-22.
43. Vollmers, H. P., J. Dammrich, H. Ribbert, S. Grassel, S. Debus, J. Heesemann, and H. K. Müller-Hermelink. 1994. Human monoclonal antibodies from stomach carcinoma patients react with Helicobacter pylori and stimulate stomach cancer cells in vitro. Cancer 74:1525-1532.
44. Weitzhandler, M., D. Kadlecek, N. Avdalovic, J. G. Forte, D. Chow, and R. R. Townsend. 1993. Monosaccharide and oligosaccharide analysis of proteins transferred to polyvinylene fluoride membranes after sodium dodecyl sulfate-polyacrylamide gel electrophoresis. J. Biol. Chem. 268:5121-5130.