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Volumn 331, Issue 1, 2005, Pages 147-152

Uroporphyria and hepatic carcinogenesis induced by polychlorinated biphenyls-iron interaction: Absence in the Cyp1a2(-/-) knockout mouse

Author keywords

Carcinogenesis; Cyp1a2( ) mice; Iron; PCBs; Porphyria

Indexed keywords

CYTOCHROME P450 1A2; CYTOCHROME P450 2B; CYTOCHROME P450 2B10; IRON DEXTRAN; POLYCHLORINATED BIPHENYL; UNCLASSIFIED DRUG;

EID: 17444411866     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.03.136     Document Type: Article
Times cited : (16)

References (40)
  • 1
    • 4644362561 scopus 로고    scopus 로고
    • Dioxin revisited: Developments since the 1997 IARC classification of dioxin as a human carcinogen
    • K. Steenland, P. Bertazzi, A. Baccarelli, and M. Kogevinas Dioxin revisited: developments since the 1997 IARC classification of dioxin as a human carcinogen Environ. Health Perspect. 112 2004 1265 1268
    • (2004) Environ. Health Perspect. , vol.112 , pp. 1265-1268
    • Steenland, K.1    Bertazzi, P.2    Baccarelli, A.3    Kogevinas, M.4
  • 2
    • 0142074373 scopus 로고    scopus 로고
    • Potential human cancer risks from exposure to PCBs: A tale of two evaluations
    • R. Golden, J. Doull, W. Waddell, and J. Mandel Potential human cancer risks from exposure to PCBs: a tale of two evaluations Crit. Rev. Toxicol. 33 2003 543 580
    • (2003) Crit. Rev. Toxicol. , vol.33 , pp. 543-580
    • Golden, R.1    Doull, J.2    Waddell, W.3    Mandel, J.4
  • 3
    • 0031882364 scopus 로고    scopus 로고
    • Absence of DNA adduct formation by phenobarbital, polychlorinated biphenyls, and chlordane in mouse liver using the 32P-postlabeling assay
    • J. Whysner, F. Montandon, R.M. McClain, J. Downing, L.K. Verna, R.E. Steward 3rd, and G.M. Williams Absence of DNA adduct formation by phenobarbital, polychlorinated biphenyls, and chlordane in mouse liver using the 32P-postlabeling assay Toxicol. Appl. Pharmacol. 148 1998 14 23
    • (1998) Toxicol. Appl. Pharmacol. , vol.148 , pp. 14-23
    • Whysner, J.1    Montandon, F.2    McClain, R.M.3    Downing, J.4    Verna, L.K.5    Steward III, R.E.6    Williams, G.M.7
  • 4
    • 0002638819 scopus 로고    scopus 로고
    • Cancer initiation by PCBs, in PCBs
    • L.W. Robertson L.G. Hansen University Press of Kentucky Lexington, Kentucky
    • G. Ludewig Cancer initiation by PCBs, in PCBs L.W. Robertson L.G. Hansen Recent advances in environmental toxicology and health effects 2001 University Press of Kentucky Lexington, Kentucky 337 371
    • (2001) Recent Advances in Environmental Toxicology and Health Effects , pp. 337-371
    • Ludewig, G.1
  • 5
    • 0033827863 scopus 로고    scopus 로고
    • Mutation frequency in the lacI gene of liver DNA from lambda/lacI transgenic mice following the interaction of PCBs with iron causing hepatic cancer and porphyria
    • R. Davies, B. Clothier, and A.G. Smith Mutation frequency in the lacI gene of liver DNA from lambda/lacI transgenic mice following the interaction of PCBs with iron causing hepatic cancer and porphyria Mutagenesis 15 2000 379 383
    • (2000) Mutagenesis , vol.15 , pp. 379-383
    • Davies, R.1    Clothier, B.2    Smith, A.G.3
  • 7
    • 84940911536 scopus 로고    scopus 로고
    • Porphyria caused by chlorinated AH receptor ligands and associated mechanisms of liver injury and cancer
    • K.M. Kadish K.M. Smith R. Guilard Elsevier Amsterdam
    • A.G. Smith Porphyria caused by chlorinated AH receptor ligands and associated mechanisms of liver injury and cancer K.M. Kadish K.M. Smith R. Guilard The porphyrin handbook 2003 Elsevier Amsterdam 169 210
    • (2003) The Porphyrin Handbook , pp. 169-210
    • Smith, A.G.1
  • 8
    • 0024520030 scopus 로고
    • Carcinogenicity of iron in conjunction with a chlorinated environmental chemical, hexachlorobenzene, in C57BL/10ScSn mice
    • A. Smith, J.R.P. Cabral, P. Carthew, J.E. Francis, and M.M. Manson Carcinogenicity of iron in conjunction with a chlorinated environmental chemical, hexachlorobenzene, in C57BL/10ScSn mice Int. J. Cancer 43 1989 492 496
    • (1989) Int. J. Cancer , vol.43 , pp. 492-496
    • Smith, A.1    Cabral, J.R.P.2    Carthew, P.3    Francis, J.E.4    Manson, M.M.5
  • 9
    • 0025014815 scopus 로고
    • Iron as a synergist for hepatocellular carcinoma induced by polychlorinated biphenyls in Ah-responsive C57BL/10ScSn mice
    • A.G. Smith, J.E. Francis, and P. Carthew Iron as a synergist for hepatocellular carcinoma induced by polychlorinated biphenyls in Ah-responsive C57BL/10ScSn mice Carcinogenesis 11 1990 437 444
    • (1990) Carcinogenesis , vol.11 , pp. 437-444
    • Smith, A.G.1    Francis, J.E.2    Carthew, P.3
  • 10
    • 0037314376 scopus 로고    scopus 로고
    • Liver pathology and hepatocarcinogenesis in a long-term mouse model of erythropoietic protoporphyria
    • L. Libbrecht, L. Meerman, F. Kuipers, T. Roskams, V. Desmet, and P. Jansen Liver pathology and hepatocarcinogenesis in a long-term mouse model of erythropoietic protoporphyria J. Pathol. 199 2003 191 200
    • (2003) J. Pathol. , vol.199 , pp. 191-200
    • Libbrecht, L.1    Meerman, L.2    Kuipers, F.3    Roskams, T.4    Desmet, V.5    Jansen, P.6
  • 11
    • 0024536151 scopus 로고
    • Oxidation of uroporphyrinogen by methylcholanthrene-induced cytochrome P-450. Essential role of cytochrome P-450d
    • J.M. Jacobs, P.R. Sinclair, W.J. Bement, R.W. Lambrecht, J.F. Sinclair, and J.A. Goldstein Oxidation of uroporphyrinogen by methylcholanthrene-induced cytochrome P-450. Essential role of cytochrome P-450d Biochem. J. 258 1989 247 253
    • (1989) Biochem. J. , vol.258 , pp. 247-253
    • Jacobs, J.M.1    Sinclair, P.R.2    Bement, W.J.3    Lambrecht, R.W.4    Sinclair, J.F.5    Goldstein, J.A.6
  • 13
    • 0037838823 scopus 로고    scopus 로고
    • Intrinsic hepatic phenotype associated with the Cyp1a2 gene as shown by cDNA expression microarray analysis of the knockout mouse
    • A.G. Smith, R. Davies, T.P. Dalton, M.L. Miller, D. Judah, J. Riley, T. Gant, and D.W. Nebert Intrinsic hepatic phenotype associated with the Cyp1a2 gene as shown by cDNA expression microarray analysis of the knockout mouse EHP Toxicogenomics 111 2003 855 861
    • (2003) EHP Toxicogenomics , vol.111 , pp. 855-861
    • Smith, A.G.1    Davies, R.2    Dalton, T.P.3    Miller, M.L.4    Judah, D.5    Riley, J.6    Gant, T.7    Nebert, D.W.8
  • 14
    • 0037094751 scopus 로고    scopus 로고
    • Decrease in 4-aminobiphenyl-induced methemoglobinemia in Cyp1a2(-/-) knockout mice
    • H.G. Shertzer, T.P. Dalton, G. Talaska, and D.W. Nebert Decrease in 4-aminobiphenyl-induced methemoglobinemia in Cyp1a2(-/-) knockout mice Toxicol. Appl. Pharmacol. 181 2002 32 37
    • (2002) Toxicol. Appl. Pharmacol. , vol.181 , pp. 32-37
    • Shertzer, H.G.1    Dalton, T.P.2    Talaska, G.3    Nebert, D.W.4
  • 18
    • 0035370158 scopus 로고    scopus 로고
    • Protection of the Cyp1a2(-/-) null mouse against uroporphyria and hepatic injury following exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • A.G. Smith, B. Clothier, P. Carthew, N.L. Childs, P.R. Sinclair, D.W. Nebert, and T.P. Dalton Protection of the Cyp1a2(-/-) null mouse against uroporphyria and hepatic injury following exposure to 2,3,7,8- tetrachlorodibenzo-p-dioxin Toxicol. Appl. Pharmacol. 173 2001 89 98
    • (2001) Toxicol. Appl. Pharmacol. , vol.173 , pp. 89-98
    • Smith, A.G.1    Clothier, B.2    Carthew, P.3    Childs, N.L.4    Sinclair, P.R.5    Nebert, D.W.6    Dalton, T.P.7
  • 19
    • 0025172709 scopus 로고
    • Chlorinated biphenyls induce cytochrome P450IA2 and uroporphyrin accumulation in cultures of mouse hepatocytes
    • P.R. Sinclair, W.J. Bement, R.W. Lambrecht, N. Gorman, and J.F. Sinclair Chlorinated biphenyls induce cytochrome P450IA2 and uroporphyrin accumulation in cultures of mouse hepatocytes Arch. Biochem. Biophys. 281 1990 225 232
    • (1990) Arch. Biochem. Biophys. , vol.281 , pp. 225-232
    • Sinclair, P.R.1    Bement, W.J.2    Lambrecht, R.W.3    Gorman, N.4    Sinclair, J.F.5
  • 20
    • 0019314739 scopus 로고
    • Studies of porphyrin synthesis in fibroblasts of patients with congenital erythropoietic porphyria and one patient with homozygous coproporphyria
    • B. Grandchamp, J.C. Deybach, M. Grelier, H. de Verneuil, and Y. Nordmann Studies of porphyrin synthesis in fibroblasts of patients with congenital erythropoietic porphyria and one patient with homozygous coproporphyria Biochim. Biophys. Acta 629 1980 577 586
    • (1980) Biochim. Biophys. Acta , vol.629 , pp. 577-586
    • Grandchamp, B.1    Deybach, J.C.2    Grelier, M.3    De Verneuil, H.4    Nordmann, Y.5
  • 21
    • 0023124846 scopus 로고
    • Hepatocarcinogenesis: A dynamic cellular perspective
    • E. Farber, and D.S. Sarma Hepatocarcinogenesis: a dynamic cellular perspective Lab. Invest. 56 1987 4 22
    • (1987) Lab. Invest. , vol.56 , pp. 4-22
    • Farber, E.1    Sarma, D.S.2
  • 22
    • 0031430858 scopus 로고    scopus 로고
    • Cytochrome P450 induction, uroporphyrinogen decarboxylase depression, porphyrin accumulation and excretion, and gender influence in a 3-week rat model of porphyria cutanea tarda
    • M.R. Franklin, J.D. Phillips, and J.P. Kushner Cytochrome P450 induction, uroporphyrinogen decarboxylase depression, porphyrin accumulation and excretion, and gender influence in a 3-week rat model of porphyria cutanea tarda Toxicol. Appl. Pharmacol. 147 1997 289 299
    • (1997) Toxicol. Appl. Pharmacol. , vol.147 , pp. 289-299
    • Franklin, M.R.1    Phillips, J.D.2    Kushner, J.P.3
  • 24
    • 0025184167 scopus 로고
    • Sex-linked hepatic uroporphyria and the induction of cytochromes P450IA in rats caused by hexachlorobenzene and polyhalogenated biphenyls
    • A.G. Smith, J.E. Francis, J.A. Green, J.B. Greig, C.R. Wolf, and M.M. Manson Sex-linked hepatic uroporphyria and the induction of cytochromes P450IA in rats caused by hexachlorobenzene and polyhalogenated biphenyls Biochem. Pharmacol. 40 1990 2059 2068
    • (1990) Biochem. Pharmacol. , vol.40 , pp. 2059-2068
    • Smith, A.G.1    Francis, J.E.2    Green, J.A.3    Greig, J.B.4    Wolf, C.R.5    Manson, M.M.6
  • 25
    • 0034952523 scopus 로고    scopus 로고
    • Hepatocellular iron accumulation and increased cell proliferation in polychlorinated biphenyl-exposed Sprague-Dawley rats and the development of hepatocarcinogenesis
    • J. Whysner, and C.X. Wang Hepatocellular iron accumulation and increased cell proliferation in polychlorinated biphenyl-exposed Sprague-Dawley rats and the development of hepatocarcinogenesis Toxicol. Sci. 62 2001 36 45
    • (2001) Toxicol. Sci. , vol.62 , pp. 36-45
    • Whysner, J.1    Wang, C.X.2
  • 26
    • 0027240017 scopus 로고
    • Enhancement by iron of hepatic neoplasia in rats caused by hexachlorobenzene
    • A.G. Smith, P. Carthew, J.E. Francis, J.R. Cabral, and M.M. Manson Enhancement by iron of hepatic neoplasia in rats caused by hexachlorobenzene Carcinogenesis 14 1993 1381 1387
    • (1993) Carcinogenesis , vol.14 , pp. 1381-1387
    • Smith, A.G.1    Carthew, P.2    Francis, J.E.3    Cabral, J.R.4    Manson, M.M.5
  • 27
    • 0031016791 scopus 로고    scopus 로고
    • Increased frequency of the haemochromatosis Cys282Tyr mutation in sporadic porphyria cutanea tarda
    • A.G. Roberts, S.D. Whatley, R.R. Morgan, M. Worwood, and G.H. Elder Increased frequency of the haemochromatosis Cys282Tyr mutation in sporadic porphyria cutanea tarda Lancet 349 1997 321 323
    • (1997) Lancet , vol.349 , pp. 321-323
    • Roberts, A.G.1    Whatley, S.D.2    Morgan, R.R.3    Worwood, M.4    Elder, G.H.5
  • 30
    • 0033152845 scopus 로고    scopus 로고
    • Primary liver cancer, other malignancies, and mortality risks following porphyria: A cohort study in Denmark and Sweden
    • M. Linet, G. Gridley, O. Nyren, L. Mellemkjaer, J. Olsen, S. Keehn, H. Adami, and J. Fraumeni Jr. Primary liver cancer, other malignancies, and mortality risks following porphyria: a cohort study in Denmark and Sweden Am. J. Epidemiol. 149 1999 1010 1015
    • (1999) Am. J. Epidemiol. , vol.149 , pp. 1010-1015
    • Linet, M.1    Gridley, G.2    Nyren, O.3    Mellemkjaer, L.4    Olsen, J.5    Keehn, S.6    Adami, H.7    Fraumeni Jr., J.8
  • 31
    • 0034800677 scopus 로고    scopus 로고
    • Liver cancer risk is increased in patients with porphyria cutanea tarda in comparison to matched control patients with chronic liver disease
    • A.L. Fracanzani, E. Taioli, M. Sampietro, E. Fatta, C. Bertelli, G. Fiorelli, and S. Fargion Liver cancer risk is increased in patients with porphyria cutanea tarda in comparison to matched control patients with chronic liver disease J. Hepatol. 35 2001 498 503
    • (2001) J. Hepatol. , vol.35 , pp. 498-503
    • Fracanzani, A.L.1    Taioli, E.2    Sampietro, M.3    Fatta, E.4    Bertelli, C.5    Fiorelli, G.6    Fargion, S.7
  • 32
    • 0028820801 scopus 로고
    • Role of cytochrome P4501A2 in chemical carcinogenesis: Implications for human variability in expression and enzyme activity
    • D.L. Eaton, E.P. Gallagher, T.K. Bammler, and K.L. Kunze Role of cytochrome P4501A2 in chemical carcinogenesis: implications for human variability in expression and enzyme activity Pharmacogenetics 5 1995 259 274
    • (1995) Pharmacogenetics , vol.5 , pp. 259-274
    • Eaton, D.L.1    Gallagher, E.P.2    Bammler, T.K.3    Kunze, K.L.4
  • 33
    • 0029963622 scopus 로고    scopus 로고
    • Human drug-metabolizing enzyme polymorphisms: Effects on risk of toxicity and cancer
    • D.W. Nebert, R.A. McKinnon, and A. Puga Human drug-metabolizing enzyme polymorphisms: effects on risk of toxicity and cancer DNA Cell Biol. 15 1996 273 280
    • (1996) DNA Cell Biol. , vol.15 , pp. 273-280
    • Nebert, D.W.1    McKinnon, R.A.2    Puga, A.3
  • 34
    • 13444252325 scopus 로고    scopus 로고
    • Toward the evaluation of function in genetic variability: Characterizing human SNP frequencies and establishing BAC-transgenic mice carrying the human CYP1A1_CYP1A2locus
    • Z. Jiang, T.P. Dalton, L. Jin, B. Wang, Y. Tsuneoka, H.G. Shertzer, R. Deka, and D.W. Nebert Toward the evaluation of function in genetic variability: characterizing human SNP frequencies and establishing BAC-transgenic mice carrying the human CYP1A1_CYP1A2locus Hum. Mutat. 25 2005 196 206
    • (2005) Hum. Mutat. , vol.25 , pp. 196-206
    • Jiang, Z.1    Dalton, T.P.2    Jin, L.3    Wang, B.4    Tsuneoka, Y.5    Shertzer, H.G.6    Deka, R.7    Nebert, D.W.8
  • 35
    • 2642510760 scopus 로고    scopus 로고
    • Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer
    • D.W. Nebert, T.P. Dalton, A.B. Okey, and F.J. Gonzalez Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer J. Biol. Chem. 279 2004 23847 23850
    • (2004) J. Biol. Chem. , vol.279 , pp. 23847-23850
    • Nebert, D.W.1    Dalton, T.P.2    Okey, A.B.3    Gonzalez, F.J.4
  • 37
    • 0033565934 scopus 로고    scopus 로고
    • Internal hazards: Baseline DNA damage by endogenous products of normal metabolism
    • P.C. Burcham Internal hazards: baseline DNA damage by endogenous products of normal metabolism Mutat. Res. 443 1999 11 36
    • (1999) Mutat. Res. , vol.443 , pp. 11-36
    • Burcham, P.C.1


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