-
1
-
-
0001947969
-
Cytomegalovirus
-
Edited by RJ Whitley & C Lopez. New York: Raven
-
Alford CA & Britt WJ (1993) Cytomegalovirus. In The Human Herpesvirus, pp. 227-255. Edited by RJ Whitley & C Lopez. New York: Raven.
-
(1993)
The Human Herpesvirus
, pp. 227-255
-
-
Alford, C.A.1
Britt, W.J.2
-
3
-
-
0028353637
-
Intramolecular cyclization of α-lithioamine synthetic equivalents: Convenient synthesis of 3-, 5-, and 6-membered ring heterocyclic nitrogen compound and elaborations of 3-membered ring systems
-
Beak P, Wu S, Yum KE & Jun MY (1994) Intramolecular cyclization of α-lithioamine synthetic equivalents: convenient synthesis of 3-, 5-, and 6-membered ring heterocyclic nitrogen compound and elaborations of 3-membered ring systems. Journal of Organic Chemistry 59:276-277.
-
(1994)
Journal of Organic Chemistry
, vol.59
, pp. 276-277
-
-
Beak, P.1
Wu, S.2
Yum, K.E.3
Jun, M.Y.4
-
4
-
-
0031974319
-
Design of fluorogenic peptide substrates for human cytomegalovirus protease based on structure-activity relationship studies
-
Bonneau PR, Plouffe C, Pelletier A, Wernic D & Poupart M-A (1998) Design of fluorogenic peptide substrates for human cytomegalovirus protease based on structure-activity relationship studies. Analytical Biochemistry 255:59-65.
-
(1998)
Analytical Biochemistry
, vol.255
, pp. 59-65
-
-
Bonneau, P.R.1
Plouffe, C.2
Pelletier, A.3
Wernic, D.4
Poupart, M.-A.5
-
5
-
-
0032539506
-
Design and synthesis of monocyclic β-lactams as mechanism based inhibitors of human cytomegalovirus protease
-
Borthwick AD, Weingarten G, Haley TM, Tomaszewski M, Wang W, Hu Z, Bedard J, Jin H, Yuen L & Mansour TS (1998) Design and synthesis of monocyclic β-lactams as mechanism based inhibitors of human cytomegalovirus protease. Bioorganic & Medicinal Chemistry Letters 8:365-370.
-
(1998)
Bioorganic & Medicinal Chemistry Letters
, vol.8
, pp. 365-370
-
-
Borthwick, A.D.1
Weingarten, G.2
Haley, T.M.3
Tomaszewski, M.4
Wang, W.5
Hu, Z.6
Bedard, J.7
Jin, H.8
Yuen, L.9
Mansour, T.S.10
-
6
-
-
16044364654
-
Structure of the human cytomegalovirus protease catalytic domain reveals a novel serine protease fold and catalytic triad
-
Chen P, Tsuge H, Almassy RJ, Gribskov CL, Katoh S, Vanderpool PL, Margosiak SA, Pinko C, Matthews DA & Kan C-C (1996) Structure of the human cytomegalovirus protease catalytic domain reveals a novel serine protease fold and catalytic triad. Cell 86:835-843.
-
(1996)
Cell
, vol.86
, pp. 835-843
-
-
Chen, P.1
Tsuge, H.2
Almassy, R.J.3
Gribskov, C.L.4
Katoh, S.5
Vanderpool, P.L.6
Margosiak, S.A.7
Pinko, C.8
Matthews, D.A.9
Kan, C.-C.10
-
7
-
-
0022445670
-
Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability
-
Denizot F & Lang R (1986) Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. Journal of Immunological Methods 89:271-277.
-
(1986)
Journal of Immunological Methods
, vol.89
, pp. 271-277
-
-
Denizot, F.1
Lang, R.2
-
10
-
-
3543097740
-
Inhibition of human cytomegalovirus protease precursor and assembly protein. Processing by peptidomimetic inhibitors of HCMV protease
-
Dô F, Massariol M-J, Lagacé L, Bailey M, Halmos T, Déziel R & Cordingley MG (1997) Inhibition of human cytomegalovirus protease precursor and assembly protein. Processing by peptidomimetic inhibitors of HCMV protease. FASEB Journal 11:A1225.
-
(1997)
FASEB Journal
, vol.11
-
-
Dô, F.1
Massariol, M.-J.2
Lagacé, L.3
Bailey, M.4
Halmos, T.5
Déziel, R.6
Cordingley, M.G.7
-
11
-
-
85077758847
-
Synthesis of L-3,4-didehydroproline: Favored orientation in the key-step elimination reaction
-
Dormoy JR (1982) Synthesis of L-3,4-didehydroproline: favored orientation in the key-step elimination reaction. Synthesis 753-756.
-
(1982)
Synthesis
, pp. 753-756
-
-
Dormoy, J.R.1
-
12
-
-
0029034742
-
Orally active β-lactam inhibitors of human leukocyte elastase. Stereospecific synthesis and structure - Activity relationships for 3,3-dialkylazetidin-2-ones
-
Finke PE, Shah SK, Fletcher DS, Ashe BM, Brause KA, Chandelier GO, Dellea PS, Hand KM, Maycock AL & Osinga DG, Underwood DJ, Weston H, Davies P & Doherty JB (1995) Orally active β-lactam inhibitors of human leukocyte elastase. Stereospecific synthesis and structure - activity relationships for 3,3-dialkylazetidin-2-ones. Journal of Medicinal Chemistry. 38:2449-2462.
-
(1995)
Journal of Medicinal Chemistry
, vol.38
, pp. 2449-2462
-
-
Finke, P.E.1
Shah, S.K.2
Fletcher, D.S.3
Ashe, B.M.4
Brause, K.A.5
Chandelier, G.O.6
Dellea, P.S.7
Hand, K.M.8
Maycock, A.L.9
Osinga, D.G.10
Underwood, D.J.11
Weston, H.12
Davies, P.13
Doherty, J.B.14
-
13
-
-
0028308504
-
The protease of herpes simplex virus type 1 is essential for functional capsid formation and viral growth
-
Gao M, Matusick-Kumar L, Hurlburt W, DiTusa SF, Newcomb WW, Brown JC, McCann III PJ, Deckmann I & Colonno RJ (1994) The protease of herpes simplex virus type 1 is essential for functional capsid formation and viral growth. Journal of Virology 68:3702-3712.
-
(1994)
Journal of Virology
, vol.68
, pp. 3702-3712
-
-
Gao, M.1
Matusick-Kumar, L.2
Hurlburt, W.3
DiTusa, S.F.4
Newcomb, W.W.5
Brown, J.C.6
McCann III, P.J.7
Deckmann, I.8
Colonno, R.J.9
-
14
-
-
0000058254
-
Assemblin, a herpes virus serine maturational proteinase and new molecular target for antivirals
-
Gibson W, Welch AR & Hall MRT (1994) Assemblin, a herpes virus serine maturational proteinase and new molecular target for antivirals. Perspectives in Drug Discovery and Design 2:413-426.
-
(1994)
Perspectives in Drug Discovery and Design
, vol.2
, pp. 413-426
-
-
Gibson, W.1
Welch, A.R.2
Hall, M.R.T.3
-
16
-
-
0028062895
-
Identification of the serine residue at the active site of the herpes simplex virus type 1 protease
-
Holwerda BC, Wittwer AJ, Duffin KL, Smith C, Toth MV, Carr LS, Weigand RC & Bryant ML (1994) Identification of the serine residue at the active site of the herpes simplex virus type 1 protease. Journal of Biological Chemistry 269:25911-25915.
-
(1994)
Journal of Biological Chemistry
, vol.269
, pp. 25911-25915
-
-
Holwerda, B.C.1
Wittwer, A.J.2
Duffin, K.L.3
Smith, C.4
Toth, M.V.5
Carr, L.S.6
Weigand, R.C.7
Bryant, M.L.8
-
17
-
-
0030923941
-
Herpesvirus proteases: Targets for novel antiviral drugs
-
Holwerda BC (1997) Herpesvirus proteases: targets for novel antiviral drugs. Antiviral Research 35:1-21.
-
(1997)
Antiviral Research
, vol.35
, pp. 1-21
-
-
Holwerda, B.C.1
-
18
-
-
0000414496
-
The Mitsunobu reaction
-
Hughes DL (1992) The Mitsunobu reaction. Organical Reactions 42:335-656.
-
(1992)
Organical Reactions
, vol.42
, pp. 335-656
-
-
Hughes, D.L.1
-
19
-
-
0028059453
-
Ganciclovir-an update of its therapeutic use in cytomegalovirus
-
Markham A & Faulds D (1994) Ganciclovir-an update of its therapeutic use in cytomegalovirus. Drugs 48:45-484.
-
(1994)
Drugs
, vol.48
, pp. 45-484
-
-
Markham, A.1
Faulds, D.2
-
20
-
-
15144347039
-
Peptidomimetic inhibitors of the human cytomegalovirus protease
-
Ogilvie W, Bailey M, Poupart M-A, Abraham A, Bhavsar A, Bonneau P, Bordeleau J, Bousquet Y, Chabot C, Duceppe J-S, Fazal G, Goulet S, Grand-Maître C, Guse I, Halmos T, Lavallée P, Leach M, Malenfant E, O'Meara J, Plante R, Plouffe C, Poirier M, Soucy F, Yoakim C & Déziel R (1997) Peptidomimetic inhibitors of the human cytomegalovirus protease. Journal of Medicinal Chemistry 40:4113-4135.
-
(1997)
Journal of Medicinal Chemistry
, vol.40
, pp. 4113-4135
-
-
Ogilvie, W.1
Bailey, M.2
Poupart, M.-A.3
Abraham, A.4
Bhavsar, A.5
Bonneau, P.6
Bordeleau, J.7
Bousquet, Y.8
Chabot, C.9
Duceppe, J.-S.10
Fazal, G.11
Goulet, S.12
Grand-Maître, C.13
Guse, I.14
Halmos, T.15
Lavallée, P.16
Leach, M.17
Malenfant, E.18
O'Meara, J.19
Plante, R.20
Plouffe, C.21
Poirier, M.22
Soucy, F.23
Yoakim, C.24
Déziel, R.25
more..
-
21
-
-
0026516706
-
Processing of the herpes simplex virus assembly protein ICP35 near its carboxy terminal end requires the product of the whole of the UL26 reading frame
-
Preston VG, Rixon FJ, McDougall IM, McGregor M & Al Kobaisi MF (1992) Processing of the herpes simplex virus assembly protein ICP35 near its carboxy terminal end requires the product of the whole of the UL26 reading frame. Virology 186:87-98.
-
(1992)
Virology
, vol.186
, pp. 87-98
-
-
Preston, V.G.1
Rixon, F.J.2
McDougall, I.M.3
McGregor, M.4
Al Kobaisi, M.F.5
-
22
-
-
0029797364
-
Unique fold and active site in cytomegalovirus protease
-
Qiu X, Culp JS, DiLella AG, Hellmig B, Hoog SS, Janson CA, Smith WW & Abdel-Meguid SS (1996) Unique fold and active site in cytomegalovirus protease. Nature 383:275-279.
-
(1996)
Nature
, vol.383
, pp. 275-279
-
-
Qiu, X.1
Culp, J.S.2
DiLella, A.G.3
Hellmig, B.4
Hoog, S.S.5
Janson, C.A.6
Smith, W.W.7
Abdel-Meguid, S.S.8
-
24
-
-
0026098790
-
A facile synthesis of chiral N-protected β-amino alcohols
-
Rodriguez M, Llinares M, Doulut S, Heitz A & Martinez J (1991) A facile synthesis of chiral N-protected β-amino alcohols. Tetrahedron Letters 32:923-926.
-
(1991)
Tetrahedron Letters
, vol.32
, pp. 923-926
-
-
Rodriguez, M.1
Llinares, M.2
Doulut, S.3
Heitz, A.4
Martinez, J.5
-
25
-
-
16044368319
-
Three-dimensional structure of human cytomegalovirus protease
-
Shieh N-S, Kurumball RG, Stevens AM, Stegeman RA, Sturman EJ, Pak JY, Wittwer AJ, Palmier MO, Wiegand RC, Holwerda BC & Stallings WC (1996) Three-dimensional structure of human cytomegalovirus protease. Nature 383:279-282.
-
(1996)
Nature
, vol.383
, pp. 279-282
-
-
Shieh, N.-S.1
Kurumball, R.G.2
Stevens, A.M.3
Stegeman, R.A.4
Sturman, E.J.5
Pak, J.Y.6
Wittwer, A.J.7
Palmier, M.O.8
Wiegand, R.C.9
Holwerda, B.C.10
Stallings, W.C.11
-
26
-
-
0028109921
-
In vitro proteolytic activity and active-site identification of the human cytomegalovirus protease
-
Stevens JT, Mapelli C, Tsao J, Hail M, O'Boyle D, Weinheimer SP & Dilanni CL (1994) In vitro proteolytic activity and active-site identification of the human cytomegalovirus protease. European Journal of Biochemistry 226:361-367.
-
(1994)
European Journal of Biochemistry
, vol.226
, pp. 361-367
-
-
Stevens, J.T.1
Mapelli, C.2
Tsao, J.3
Hail, M.4
O'Boyle, D.5
Weinheimer, S.P.6
Dilanni, C.L.7
-
27
-
-
0029793554
-
A new serine-protease fold revealed by the crystal structure of human cytomegalovirus protease
-
Tong L, Qian C, Massariol M-J, Bonneau PR, Cordingley MG & Lagacé L (1996) A new serine-protease fold revealed by the crystal structure of human cytomegalovirus protease. Nature 383:272-275.
-
(1996)
Nature
, vol.383
, pp. 272-275
-
-
Tong, L.1
Qian, C.2
Massariol, M.-J.3
Bonneau, P.R.4
Cordingley, M.G.5
Lagacé, L.6
-
28
-
-
0028148047
-
Foscarnet - A reappraisal of its antiviral activity, pharmacokinetic properties and therapeutic use in immunocompromised patients with viral infections
-
Wagstaff AJ & Bryson HM (1994) Foscarnet - a reappraisal of its antiviral activity, pharmacokinetic properties and therapeutic use in immunocompromised patients with viral infections. Drugs 48:199-226.
-
(1994)
Drugs
, vol.48
, pp. 199-226
-
-
Wagstaff, A.J.1
Bryson, H.M.2
-
29
-
-
0027428432
-
Herpesvirus proteinase: Site-directed mutagenesis used to study maturational, release, and inactivation cleavage sites of precursor and to identify a possible catalytic site serine and histidine
-
Welch AR, McNally LM, Hall MRT & Gibson W (1993) Herpesvirus proteinase: site-directed mutagenesis used to study maturational, release, and inactivation cleavage sites of precursor and to identify a possible catalytic site serine and histidine. Journal of Virology 67:7360-7372.
-
(1993)
Journal of Virology
, vol.67
, pp. 7360-7372
-
-
Welch, A.R.1
McNally, L.M.2
Hall, M.R.T.3
Gibson, W.4
-
30
-
-
0030071356
-
Asymmetric deprotonation by BuLi/(-) sparteine: Convenient and highly enantioselective syntheses of (S)-2-aryl-Boc-pyrrolidine
-
Wu S, Lee S & Beak P (1996) Asymmetric deprotonation by BuLi/(-) sparteine: convenient and highly enantioselective syntheses of (S)-2-aryl-Boc-pyrrolidine. Journal of the American Chemical Society 118:715-721.
-
(1996)
Journal of the American Chemical Society
, vol.118
, pp. 715-721
-
-
Wu, S.1
Lee, S.2
Beak, P.3
-
31
-
-
15644380718
-
β-Lactam derivatives as inhibitors of human cytomegalovirus protease
-
in press
-
Yoakim C, Ogilvie W, Cameron D, Chabot C, Guse I, Haché B, Naud J, O'Meara J, Plante R & Déziel R (1998) β-Lactam derivatives as inhibitors of human cytomegalovirus protease. Journal of Medicinal Chemistry (in press).
-
(1998)
Journal of Medicinal Chemistry
-
-
Yoakim, C.1
Ogilvie, W.2
Cameron, D.3
Chabot, C.4
Guse, I.5
Haché, B.6
Naud, J.7
O'Meara, J.8
Plante, R.9
Déziel, R.10
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