Design of fluorogenic peptide substrates for human cytomegalovirus protease based on structure - Activity relationship studies

Analytical Biochemistry

Volumn 255, Issue 1, 1998, Pages 59-65

  Bonneau, Pierre R ^a   Plouffe, Céline ^a   Pelletier, Alex ^a   Wernic, Dominik ^a   Poupart, Marc André ^a  

^a BOEHRINGER INGELHEIM CANADA LTD   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYMES; PEPTIDES;

FLUOROGENIC SUBSTRATE; FLUOROGENICS; HUMAN CYTOMEGALOVIRUS; IDENTICAL CONDITIONS; PEPTIDE SUBSTRATES; STRUCTURE ACTIVITY RELATIONSHIPS; STRUCTURE ACTIVITY STUDY; VARIOUS SUBSTRATES;

SUBSTRATES;

COUMARIN DERIVATIVE; PEPTIDE; PROTEINASE; VIRUS ENZYME;

AMINO ACID SEQUENCE; ARTICLE; ENZYME DEGRADATION; ENZYME SUBSTRATE; HUMAN CYTOMEGALOVIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; STRUCTURE ACTIVITY RELATION; VIRUS CAPSID;

FELIS CATUS; HUMAN HERPESVIRUS 5; MIRIDAE;

EID: 0031974319     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1006/abio.1997.2445     Document Type: Article

References (30)

1. Mocarski E. S. Virology. 1996;Lippincott-Raven, Philadelphia. p. 2447-2492.
2. Britt W. J., Alford C. A. Fields B. N., Knipe D. M., Howley P. M. Virology. 1996;2493-2523 Lippincott-Raven, Philadelphia.
3. Preston V. G., Coates J. A. V., Rixon F. J. J. Virol. 45:1983;1056-1064.
4. Gao M., Matusick-Kumar L., Hurlburt W., DiTusa S. F., Newcomb W. W., Brown J. C., McCann P. J. III, Deckman I., Colonno R. J. J. Virol. 68:1994;3702-3712.
5. Matusick-Kumar L., McCann P. J. III, Robertson B. J., Newcomb W. W., Brown J. C., Gao M. J. Virol. 69:1995;7113-7121.
6. Casjens S., King J. Annu. Rev. Biochem. 44:1975;555-611.
7. Gibson W., Welch A. R., Hall M. R. T. Perspect. Drug Discovery Des. 2:1995;413-426.
8. Matayoshi E. D., Wang G. T., Krafft G., Erickson J. Science. 247:1990;954-958.
9. Wang G. T., Chung C. C., Holzman T. F., Krafft G. A. Anal. Biochem. 210:1993;351-359.
10. Pennington, N. W. Zaydenberg, I. Byrnes, M. E. de Chastonay, J. Malcolm, B. A. Swietnicki, W. Farmerie, W. G. Scarborough, P. E. Dunn, B. M. 1993, in, Peptides 1992: Proceedings of the 22nd European Peptide Symposium, Schneider, C. H.Eberle, A. N. 936, 937, Escom, Leiden, The Netherlands.
11. Pennington M. W., Thornberry N. A. Peptide Res. 7:1994;72-76.
12. Knight G. C. Methods Enzymol. 248:1995;18-34.
13. Jean F., Basak A., DiMaio J., Seidah N. G., Lazure C. Biochem. J. 307:1995;689-695.
14. Levine M. L., Michener M. L., Toth M. V., Holwerda B. C. Anal. Biochem. 247:1997;83-88.
15. Holskin B. P., Bukhtiyarova M., Dunn B. M., Baur P., de Chastonay J., Pennington M. W. Anal. Biochem. 227:1995;148-155.
16. Pinko C., Margosiak S. A., Vanderpool D., Gutowski J. C., Condon B., Kan C.-C. J. Biol. Chem. 270:1995;23634-23640.
17. Handa B. K., Keech E., Conway E. A., Broadhurst A., Ritchie A. Antivir. Chem. Chemother. 6:1995;255-261.
18. Toth, M. V. Wittner, A. J. Holwerda, B. C. 1996.
19. Bodanszky M., Bodanszky A. The Practice of Peptide Synthesis. 1984;Springer-Verlag, New York.
20. Bradford M. M. Anal. Biochem. 72:1976;248-254.
21. Erithacus Software Ltd. 1989-1992, Grafit, Leatherbarrow, London, UK.
22. Meldal M., Breddam K. Anal. Biochem. 195:1991;141-147.
23. Gron H., Meldal M., Breddam K. Biochemistry. 31:1992;6011-6018.
24. Margosiak S. A., Vanderpool D. L., Sisson W., Pinko C., Kan C.-C. Biochemistry. 35:1996;5300-5307.
25. Zimmerman M., Yurewicz E., Patel G. Anal. Biochem. 70:1976;258-262.
26. Barrett A. J. Methods in Enzymology. 1994;1-765 Academic Press, San Diego.
27. Sardana V. V., Wolfgang J. A., Veloski C. A., Long W. J., LeGrow K., Wolanski B., Emini E. A., LaFemina R. L. J. Biol. Chem. 269:1994;14337-14340.
28. LaFemina R. L., Bakshi K., Long W. J., Pramanik B., Veloski C. A., Wolanski B. S., Marcy A. I., Hazuda D. J. J. Virol. 70:1996;4819-4824.
29. Baum E. Z., Johnston S. H., Bebernitz G. A., Gluzman Y. Anal. Biochem. 237:1996;129-134.
30. Schechter J., Berger A. Phil. Trans. R. Soc. London Ser. B. 257:1970;249-264.