Abnormal p53 expression is rare in clinically localized human prostate cancer: Comparison between immunohistochemical and molecular detection of p53 mutations

Prostate

Volumn 31, Issue 4, 1997, Pages 209-215

  Mottaz, Alain E ^a   Markwalder, Regula ^a   Fey, Martin F ^a   Klima, Irena ^a   Merz, Vincent W ^a   Thalmann, George N ^a   Ball, Roland K ^a   Studer, Urs E ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Immunohistochemistry; p53; Prostate cancer; SSCP

Indexed keywords

ARTICLE; CANCER INVASION; GENE LOCATION; GENE MUTATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; SINGLE STRAND CONFORMATION POLYMORPHISM; TUMOR SUPPRESSOR GENE;

ADENOCARCINOMA; ADULT; AGED; DNA; GENES, P53; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PROSTATIC NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0030988343     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0045(19970601)31:4<209::AID-PROS1>3.0.CO;2-F     Document Type: Article

References (31)

1. American Cancer Society: "Cancer Facts and Figures 1994." Atlanta: American Cancer Society.
2. Levi F, Lucchini F, La Vecchia C: Worldwide patterns of cancer mortality, 1985-89. Eur J Cancer Prev 3:109-143, 1994.
3. Potosky AL, Miller BA, Albertsen PC, Kramer BX: The role of increasing detection in the rising incidence of prostate cancer. JAMA 273:548-552, 1995.
4. Mettlin CJ, Murphy GP, McGinnis L, Menck HR: The National Cancer Data Base Report on prostate cancer. Cancer 76:1104-1112, 1995.
5. Nigro JM, Baker SJ, Presinger AC, Jessup JM, Hostetter R, Cleary K, Bigner SH, Davidson N, Baylin S, Devilee P, Glover T, Collins FS, Weston A, Modali A, Harris CC, Vogelstein B: Mutations in the p53 gene occur in diverse human tumor types. Nature 342:705-708, 1989.
6. Levine AJ, Momand J, Finlay CA: The p53 tumor suppressor gene. Nature 351:453-456, 1991.
7. Isaacs WB, Carter BS, Ewing CM: Wild-type p53 suppresses growth of human prostate cancer cells containing mutant p53 alleles. Cancer Res 51:4716-4720, 1991.
8. Vojtesek B, Bartek J, Midgley CA, Lane DP: An immunochemical analysis of the human nuclear phosphoprotein p53: New monoclonal antibodies and epitope mapping using recombinant p53. J Immunol Methods 151: 237-244, 1992.
9. van der Berg FM, Baas IO, Polak MM, Offerhaus GJA: Detection of p53 overexpression in routinely paraffin embedded tissue of human carcinomas, using a novel target unmasking fluid (TUF). Am J Pathol 142:381-385, 1993.
10. Beckstead JH: Improved antigen retrieval in formalin-fixed, paraffin-embedded tissues. Appl Immunohistochem 2:274-281, 1994.
11. Thor AD, Moore DH, Edgerton SM, Kawasaki ES, Reihsaus E, Lynch HT, Marcus JN, Schwartz L, Chen LC, Mayall BH, Smith HS: Accumulation of p53 tumor suppression gene protein: An independent marker of prognosis in breast cancers. J Natl Cancer Inst 84:845-855, 1992.
12. Sarkar FH, Li Y-W, Crissman JD: A method for PCR sequencing of the p53 gene from a single 10-μm frozen or paraffin-embedded tissue section. BioTechniques 15: 36-38, 1993.
13. Orita M, Suzuki Y, Hayashi K: Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction. Genomics 5:874-879, 1989.
14. Orita M, Iwahana H, Kanazawa H, Hayashi K, Sekiya T: Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proc Natl Acad Sci USA 86:2766-2770, 1989.
15. Chaubert P, Bautista D, Benhattar J: An improved method for rapid screening of DNA mutations by nonradioactive single-strand conformation polymorphism procedure. BioTechniques 15:586, 1993.
16. Hsu LC, Metcalf RA, Sun T, Welsh JA, Wang NJ, Harris CC: Mutational hotspot in the p53 gene in human hepa tocellular carcinomas. Nature 350:427-428, 1991.
17. Carroll AG, Voeller HJ, Sugars L, Gelmann EP: p53 oncogene mutations in three human prostate cancer cell lines. Prostate 23:123-134, 1993.
18. Bassam BJ, Caetano-Anollés G, Gresshoff PM: Fast and sensitive silver staining of DNA in polyacrylamide gels. Anal Biochem 196:80-83, 1991.
19. Greenblatt MS, Bennett WP, Hollstein M, Harris CC: Mutations in the p53 tumor suppressor gene, clues to cancer etiology and molecular pathogenesis. Cancer Res 54:4855-4878, 1994.
20. Kubota Y, Shuin T, Uemura H, Fujinami K, Miyamoto H, Torigoe S, Dobashi Y, Kitamura H, Iwasaki Y, Donenberg K, Donenberg PV: Tumor suppressor gene p53 mutations in human prostate cancer. Prostate 27: 18-24, 1995.
21. Aprikian AG, Sarkis AS, Fair WR, Zhang Z-F, Fuks Z, Cordon-Cardo C: Immunohistochemical determination of p53 protein nuclear accumulation in prostatic adenocarcinoma. J Urol 151:1276-1280, 1994.
22. Visakorpi T, Kallioniemi O, Heikkinen A, Koivula T, Isola J: Small subgroup of aggressive highly proliferative prostatic carcinomas defined by p53 accumulation. J Natl Cancer Inst 84:883-887, 1992.
23. Heidenberg HB, Sesterhenn IA, Gaddipati JP, Weghorst CM, Buzard GS, Moul JW, Srivastava S: Alteration of the tumor suppressor gene p53 in a high fraction of hormone refractory prostate cancer. J Urol 154:414-421, 1995.
24. Thomas DJ, Robinson M, King P, Hasan T, Charlton R, Martin J, Carr TW, Neal DE: p53 expression and clinical outcome in prostate cancer. Br J Urol 72:778-781, 1993.
25. Bruner JM, Connelly JH, Saya H: p53 protein immunostaining in routinely processed paraffin-embedded sections. Mod Pathol 6:189-194, 1993.
26. Baas IO, Mulder J-WR, Offerhaus GJA, Vogelstein B, Hamilton SR: An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms. J Pathol 172:5-12, 1994.
27. Moyret C, Theillet C, Puig PL, Molés J-P, Thomas G, Hamelin R: Relative efficiency of denaturing gradient gel electrophoresis and single strand conformation polymorphism in the detection of mutations in exons 5 to 8 of the p53 gene. Oncogene 9:1739-1743, 1994.
28. Sheffield VC, Beck JS, Kwitek AE, Sandstrom DW, Stone EM: The sensitivity of single-strand conformation polymorphism analysis for the detection of single base substitutions. Genomics 16:325-332, 1993.
29. Voeller HJ, Sugars LY, Pretlow T, Gelmann EP: p53 oncogene mutations in human prostate cancer specimens. J Urol 151:492-495, 1994.
30. Van Veldhuizen PJ, Sadasivan R, Garcia F, Austerfield MS, Stephen RL: Mutant p53 expression in prostate carcinoma. Prostate 22:23-30, 1993.
31. Chi S-G, deVere White RW, Meyers FJ, Siders DB, Lee F, Gumerlock PH: p53 in prostate cancer: Frequent expressed transition mutations. J Natl Cancer Inst 86:926-933, 1994.