PRK, a cell cycle gene localized to 8p21, is downregulated in head and neck cancer

Genes Chromosomes and Cancer

Volumn 27, Issue 3, 2000, Pages 332-336

  Dai, Wei ^a   Li, Yaqin ^a   Ouyang, Bin ^a   Pan, Huiqi ^a   Reissmann, Peter ^a   Li, Jian ^a   Wiest, Jonathan ^a   Stambrook, Peter ^a   Gluckman, Jack L ^a   Noffsinger, Amy ^a   Bejarano, Pablo ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CARCINOGENESIS; CELL CYCLE; CHROMOSOME 8P; DNA DAMAGE; DOWN REGULATION; GENE EXPRESSION SYSTEM; GENE LOCUS; HEAD CANCER; HUMAN; HUMAN CELL; NECK CANCER; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA;

CARCINOMA, SQUAMOUS CELL; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 8; DOWN-REGULATION; GENES, CDC; HEAD AND NECK NEOPLASMS; HUMANS; PROTEIN-SERINE-THREONINE KINASES; RNA, MESSENGER;

EID: 17144458001     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2264(200003)27:3<332::AID-GCC15>3.0.CO;2-K     Document Type: Article

References (29)

1. Bockmuhl U, Wolf G, Schmidt S, Schwendel A, Jahnke V, Dietel M, Petersen I. 1998. Genomic alterations associated with malignancy in head and neck cancer. Head Neck 20:145-151.
2. Donahue PJ, Alberts GF, Guo Y, Winkels JA. 1995. Identification by targeted differential display of an immediate early gene encoding a putative serine/threonine kinase. J Biol Chem 270:10351-10357.
3. Fenton R, Glover DM. 1993. A conserved mitotic kinase active at late anaphase-telophase in syncytial Drosophila embryos. Nature 363:637-640.
4. Golsteyn RM, Schultz SJ, Bartek J, Ziemiecki A, Ried T, Nigg EA. 1994. Cell cycle analysis and chromosomal localization of human Plk1, a putative homologue of the mitotic kinases Drosophila polo and Sacchromyces cerevisiae Cdc5. J Cell Sci 107:1509-1517.
5. Hamanaka R, Maloid S, Smith MR, O'Connor CD, Longo DL, Ferris DK. 1994. Cloning and characterization of human and murine homologues of the Drosophila polo serine/threonine kinase. Cell Growth Diff 5:249-257.
6. Heng HHQ, Tsui L. 1993. Models of DAPI banding and simultaneous in situ hybridization. Chromosoma 102:325-332.
7. Heng HHQ, Squire J, Tsui L. 1992. High resolution mapping of mammalian genes by in situ hybridization to free chromatin. Proc Natl Acad Sci USA 89:9509-9513.
8. Hermeking H, Lengauer C, Polyak K, He TC, Zhang L, Thiagalingam S, Kinzler KW, Vogelstein B. 1997. 14-3-3 sigma is a p53-regulated inhibitor of G2/M progression. Molec Cell 1:3-11.
9. Hunter T, Pines J. 1994. Cyclins and cancer. II. Cyclin D and CDK inhibitors come of age. Cell 79:573-582.
10. Imbett A, Chaffanet M, Essioux L, Noguchi T, Adelade J, Kerangueven P, Paslier DL, Bonaiti-Pellie C, Sobol H, Birnbaum D, Pebusque MJ. 1996. Integrated map of the chromosome 8p12-p21 region, a region involved in human cancers and Werner syndrome. Genomics 32:29-38.
11. Kamb A. 1995. Cell cycle regulators and cancer. Trend Genetics 11:136-140.
12. Kitada K, Johnson AL, Johnston LH, Sugino A. 1993. A multicopy supressor gene of the Saccharomyces cerevisiae G1 cell cycle mutant gene dbf4 encodes a protein kinase and is identified as CDC5. Molec Cell Biol 13:4445-1457.
13. Kumagai A, Dunphy GW. 1996. Purification and molecular cloning of Plx1, a Cdc25-stimulatory kinase from Xenopus egg extracts. Science 273:1377-1380.
14. Laake K, Odegard A. 1997. Loss of heterozygosity at 11q23 in breast carcinomas: indication for involvement of a gene distal and close to ATM. Genes Chromosomes Cancer 18:175-180.
15. Li B, Ouyang B, Pan P, Reissmann PT, Slamon DJ, Arceci R, Stambrook P, Dai W. 1996. Prk, a cyctokine-inducible human protein serine/threonine kinase whose expression appears to be down-regulated in lung carcinomas. J Biol Chem 271:19402-19408.
16. Li YQ, Wang LJ, Stambrook PJ, McDonald JS, Gleich LL, Munck-Wikland E, Dacic S, Wilson K, Gluckman JL, Pavilic ZP. 1995. Altered p53 in microdissected, metachronous premalignant and malignant oral lesions from the same patients. J Clin Pathol 48:269-272.
17. Li YQ, Pavilic ZP, Wang LJ, Wang X, Gleich LL, Bidding P, Gastside PS, Wilson KM, Gluckman JL, Stambrook PJ. 1997. Loss of heterozygosity on chromosome 17p13 (p53) and 13q14 (Rb1) in squamous cell carcinoma of the head and neck. Int J Oncol 10:1235-1240.
18. Nigg EA. 1998. Polo-like kinases: positive regulators of cell division from start to finish. Curr Opin Cell Biol 10:776-783.
19. Ouyang B, Pan P, Luo L, Li J, Stambrook P, Li B, Dai W. 1997. Human Prk is a conserved protein serine/threonine kinase involved in regulating M phase function. J Biol Chem 272:28646-28651.
20. Peng CY, Graves PR, Thomas RS, Wu Z, Shaw AS, Piwnica-Worms H. 1997. Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science 277:1501-1505.
21. Sanchez Y, Wong C, Thomas RS, Richman R, Wu Z, Piwinica-Worms H, Ellege SJ. 1997. Conservation of the chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science 277:1497-1051.
22. Sherr CJ. 1996. Cancer cell cycle. Science 274:1672-1677.
23. Simmons DL, Neel BG, Stevens R, Evett G, Erikson RL. 1992. Identification of an early-growth-response gene encoding a putative prorein kinase. Molec Cell Biol 12:4164-4169.
24. Smith MR, Wilson ML, Hamanaka R, Chase D, Kung H, Longo DL, Ferris DK. 1997. Malignant transformation of mammalian cells initiated by constitutive expression of polo-like kinase. Biochem Biophys Res Commun 234:397-405.
25. Spurr NK, Blanton S, Clarke BR, Cottingham R, Daiger S, Drayna D, Faber P, horrigan S, Kas K, Kirchgessner C, Kumar S, Leach RJ, Luedecke HJ, Nakamura Y, Pebusque MJ, Ranta S, Sim E, Sulivan LS, Takle L, Vance J, Wagner M, Wells D, Westbrook C, Yaremko L, Zaletayev D, Zuffardi O, Wood S. 1995. Report and abstracts of second international workshop on human chromosome 8 mapping 1994. Cytogenet Cell Genet 68:148-155.
26. Sunkel, CE, Glover DM. 1988. Polo: a mitotic mutant of Drosophila displaying abnormal spindle poles. J Cell Sci 89:25-38.
27. INK4A gene in multiple myeloma. Br J Hacmatol 101:558-564.
28. Toczyski DP, Galgoczy DJ, Hartwell LH. 1997. CDC5 and CKII control adaptation to the yeast DNA damage checkpoint. Cell 90:1097-1106.
29. Xu Y, Ashley T, Brained EE, Bronson RT, Meyn MS, Baltimore D. 1996. Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphomas. Genes Dev 10:2411-2422.