Optical detection and discrimination of cystic fibrosis-related genetic mutations using oligonucleotide-nanoparticle conjugates

Analytical and Bioanalytical Chemistry

Volumn 381, Issue 6, 2005, Pages 1122-1129

  Murphy, Deirdre ^a   Redmond, Gareth ^a  

^a UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

Cystic fibrosis; Mutation detection; Oligonucleotide nanoparticle conjugate; Optical melting curve

Indexed keywords

DISEASES; GENETIC ENGINEERING; NANOSTRUCTURED MATERIALS; NUCLEIC ACIDS; OPTICAL PROPERTIES; OPTICAL RESOLVING POWER; ORGANIC POLYMERS; SILICA GEL;

CYSTIC FIBROSIS; MUTATION CURVE; NANOPARTICLE CONJUGATE; OLIGONUCLEOTIDE; OPTICAL MELTING CURVE;

MUTAGENESIS;

CFTR PROTEIN, HUMAN; GOLD; OLIGONUCLEOTIDE; PLASMA PROTEIN; SILICA GEL; SILICON DIOXIDE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ARTICLE; BASE MISPAIRING; CHEMISTRY; COMPARATIVE STUDY; CYSTIC FIBROSIS; GENETICS; HUMAN; MUTATION; NANOTECHNOLOGY; NUCLEOTIDE SEQUENCE; PARTICLE SIZE; PATHOLOGY; SOLUTION AND SOLUBILITY; TEMPERATURE;

BASE PAIR MISMATCH; BASE SEQUENCE; BLOOD PROTEINS; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; GOLD; HUMANS; MUTATION; NANOTECHNOLOGY; OLIGONUCLEOTIDES; PARTICLE SIZE; SILICON DIOXIDE; SOLUTIONS; TEMPERATURE;

EID: 17144427347     PISSN: 16182642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00216-004-3030-2     Document Type: Article

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