CXC chemokine receptor 4 expression and function in human anaplastic thyroid cancer cells

Journal of Clinical Endocrinology and Metabolism

Volumn 88, Issue 1, 2003, Pages 408-416

  Hwang, Jung Hwan ^a   Hwang, Jin Hee ^a   Chung, Hyo Kyun ^a   Kim, Dong Wook ^a   Hwang, Eun Suk ^a   Suh, Jae Mi ^a   Kim, Ho ^a   You, Kwan Hee ^b   Kwon, O Yu ^a   Ro, Heung Kyu ^a   Jo, Deog Yeon ^a   Shong, Minho ^a  

^a Chungnam National University College of Medicine   (South Korea)

^b Chungnam National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; CHEMOKINE RECEPTOR CXCR4; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN P70; S6 KINASE; WORTMANNIN;

ARTICLE; CANCER CELL; CELL ACTIVATION; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL SELECTION; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; THYROID CARCINOMA;

CARCINOMA; CELL DIVISION; CELL SURVIVAL; CHEMOKINES, CXC; DNA-BINDING PROTEINS; ENZYME ACTIVATION; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; RECEPTORS, CXCR4; REFERENCE VALUES; RIBOSOMAL PROTEIN S6 KINASES; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR; THYROID NEOPLASMS; TRANS-ACTIVATORS; TUMOR CELLS, CULTURED;

JANUS;

EID: 0037240931     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2002-021381     Document Type: Article

References (39)

1. Demeter JG, De Jong SA, Lawrence AM, Paloyan C 1991 Anaplastic thyroid carcinoma: risk factors and outcome. Surgery 110:956-961
2. Vescini F, Di Gaetano P, Vigna E, Pascoli A, Cacciari M 2000 Anaplastic thyroid carcinoma in a 49-year-old woman with a long-standing goiter. A case report. Minerva Endocrinol 25:81-83
3. Tennvall J, Lundell G, Hallquist A, Wahlberg P, Wallin G, Tibblin S 1994 Combined doxorubicin, hyperfractionated radiotherapy, and surgery in anaplastic thyroid carcinoma. Report on two protocols. The Swedish Anaplastic Thyroid Cancer Group. Cancer 74:1348-1354
4. Komoike Y, Tamaki Y, Sakita I, Tomita N, Ohue M, Sekimoto M, Miyazaki M, Kadota M, Masuda N, Ooka M, Ohnishi T, Nakano Y, Kozaki T, Kobayashi T, Matsuura N, Ikeda T, Horii A, Monden M 1999 Comparative genomic hybridization defines frequent loss on 16p in human anaplastic thyroid carcinoma. Int J Oncol 14:1157-1162
5. Haigh PI, Ituarte PH, Wu HS, Treseler PA, Posner MD, Quivey JM, Duh Qy, Clark OH 2001 Completely resected anaplastic thyroid carcinoma combined with adjuvant chemotherapy and irradiation is associated with prolonged survival. Cancer 91:2335-2342
6. Nagayama Y, Nishihara E, Namba H, Yokoi H, Hasegawa M, Mizuguchi H, Hayakawa T, Hamada H, Yamashita S, Niwa M 2001 Targeting the replication of adenovirus to p53-defective thyroid carcinoma with a p53-regulated Cre/loxP system. Cancer Gene Ther 8:36-44
7. Sera N, Ashizawa K, Ando T, Ide A, Abe Y, Usa T, Tominaga T, Ejima E, Hayashi T, Shimokawa I, Eguchi K 2000 Anaplastic changes associated with p53 gene mutation in differentiated thyroid carcinoma after insufficient radioactive iodine (131I) therapy. Thyroid 10:975-979
8. Baggiolini M 1998 Chemokines and leukocyte traffic. Nature 392:565-568
9. Kim CH, Broxmeyer HE 1999 SLC/exodus2/6Ckine/TCA4 induces chemotaxis of hematopoietic progenitor cells: differential activity of ligands of CCR7, CXCR3, or CXCR4 in chemotaxis vs. suppression of progenitor proliferation. J Leuk Biol 66:455-461
10. Aiuti A, Tavian M, Cipponi A, Ficara F, Zappone E, Hoxie J, Peault B, Bordignon C 1999 Expression of CXCR4, the receptor for stromal cell-derived factor-1 on fetal and adult human lympho-hematopoietic progenitors. Eur J Immunol 29:1823-1831
11. Muller A, Homey B, Soto H, Ge N, Catron D, Buchanan ME, McClanahan T, Murphy E, Yuan W, Wagner SN, Barrera JL, Mohar A, Verastegui E, Zlotnik A 2001 Involvement of chemokine receptors in breast cancer metastasis. Nature 410:50-56
12. Aust G, Sittig D, Steinert M, Lamesch P, Lohmann T 2002 Graves' disease is associated with an altered CXCR3 and CCR5 expression in thyroid-derived compared to peripheral blood lymphocytes. Clin Exp Immunol 127:479-485
13. Aust G, Steinert M, Kiessling S, Kamprad M, Simchen C 2001 Reduced expression of stromal-derived factor 1 in autonomous thyroid adenomas and its regulation in thyroid-derived cells. J Clin Endocrinol Metab 86:3368-3376
14. Fagin JA, Matsuo K, Karmakar A, Chen DL, Tang SH, Koeffler HP 1993 High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas. J Clin Invest 91:179-184
15. Nagayama Y, Izumi M, Ashizawa K, Kiriyama T, Yokoyama N, Morita S, Ohtakara S, Fukuda T, Eguchi K, Morimoto I 1987 Inhibitory effect of interferon-γ on the response of human thyrocytes to thyrotropin (TSH) stimulation: relationship between the response to TSH and the expression of DR antigen. J Clin Endocrinol Metab 64:949-953
16. Nagasawa T, Kikutani H, Kishimoto T 1994 Molecular cloning and structure of a pre-B-cell growth-stimulating factor. Proc Natl Acad Sci USA 91:2305-2309
17. Hesselgesser J, Taub D, Baskar P, Greenberg M, Hoxie J, Kolson DL, Horuk R 1998 Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1α is mediated by the chemokine receptor CXCR4. Curr Biol 8:595-598
18. Serrano M, Monroy C, Rodriguez-Garcia JL, Pais JR, Fernandez-Garrido M 1994 The combined treatment of anaplastic thyroid carcinoma. An Med Interna 11:288-290
19. Garcia-Rostan G, Tallini G, Herrero A, D'Aquila TG, Carcangiu ML, Rimm DL 1999 Frequent mutation and nuclear localization of β-catenin in anaplastic thyroid carcinoma. Cancer Res 59:1811-1815
20. Kitamura Y, Shimizu K, Tanaka S, Ito K, Emi M 2000 Allelotyping of anaplastic thyroid carcinoma: frequent allelic losses on 1q, 9p, 11, 17, 19p, and 22q. Genes Chromosomes Cancer 27:244-251
21. Geminder H, Sagi-Assif O, Goldberg L, Meshel T, Rechavi G, Witz IP, Ben-Baruch A 2001 A possible role for CXCR4 and its ligand, the CXC chemokine stromal cell-derived factor-1, in the development of bone marrow metastases in neuroblastoma. J Immunol 167:4747-4757
22. Cheng ZJ, Zhao J, Sun Y, Hu W, Wu YL, Cen B, Wu GX, Pei G 2000 β-Arrestin differentially regulates the chemokine receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between β-arrestin and CXCR4. J Biol Chem 275:2479-2485
23. Tarasova NI, Stauber RH, Michejda CJ 1998 Spontaneous and ligand-induced trafficking of CXC-chemokine receptor 4. J Biol Chem 273:15883-15886
24. Marchese A, Benovic JL 2001 Agonist-promoted ubiquitination of the G protein-coupled receptor CXCR4 mediates lysosomal sorting. J Biol Chem 276:45509-45512
25. Either F, Cui Y, Hudkins KL, Alpers CE 1998 Chemokine receptor (CXCR4) mRNA-expressing leukocytes are increased in human renal allograft rejection. Transplantation 66:1551-1557
26. Mohle R, Failenschmid C, Bautz F, Kanz L 1999 Overexpression of the chemokine receptor CXCR4 in B cell chronic lymphocytic leukemia is associated with increased functional response to stromal cell-derived factor-1 (SDF-1). Leukemia 13:1954-1959
27. Bajetto A, Bonavia R, Barbero S, Florio T, Schettini G 2001 Chemokines and their receptors in the central nervous system. Front Neuroendocrinol 22:147-184
28. Ganju RK, Brubaker SA, Meyer J, Dutt P, Yang Y, Qin S, Newman W, Groopman JE 1998 The α-chemokine, stromal cell-derived factor-1α, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways. J Biol Chem 273:23169-23175
29. Oh JW, Drabik K, Kutsch O, Choi C, Tousson A, Benveniste EN 2001 CXC chemokine receptor 4 expression and function in human astroglioma cells. J Immunol 166:2695-2704
30. Franitza S, Kollet O, Brill A, Vaday GG, Petit I, Lapidot T, Alon R, Lider O 2002 TGF-β1 enhances SDF-1α-induced chemotaxis and homing of naive T cells by up-regulating CXCR4 expression and downstream cytoskeletal effector molecules. Eur J Immunol 32:193-202
31. Wang JF, Park IW, Groopman JE 2000 Stromal cell-derived factor-1α stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells: roles of phosphoinositide-3 kinase and protein kinase C. Blood 95:2505-2513
32. Sotsios Y, Whittaker GC, Westwick J, Ward SG 1999 The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes. J Immunol 163:5954-5963
33. Lataillade JJ, Clay D, Bourin P, Herodin F, Dupuy C, Jasmin C, Bousse-Kerdiles MC 2002 Stromal cell-derived factor 1 regulates primitive hematopoiesis by suppressing apoptosis and by promoting G(0)/G(1) transition in CD34(+) cells: evidence for an autocrine/paracrine mechanism. Blood 99:1117-1129
34. Han Y, He T, Huang DR, Pardo CA, Ransohoff RM 2001 TNF-α mediates SDF-1α-induced NF-κB activation and cytotoxic effects in primary astrocytes. J Clin Invest 108:425-435
35. Vila-Coro AJ, Rodriguez-Frade JM, Martin De Ana A, Moreno-Ortiz MC, Martinez-A C, Mellado M 1999 The chemokine SDF-1α triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway. FASEB J 13:1699-1710
36. Zhang XF, Wang JF, Matczak E, Proper JA, Groopman JE 2001 Janus kinase 2 is involved in stromal cell-derived factor-1α-induced tyrosine phosphorylation of focal adhesion proteins and migration of hematopoietic progenitor cells. Blood 97:3342-3348
37. Kulik G, Klippel A, Weber MJ 1997 Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt. Mol Cell Biol 17:1595-1606
38. Harada H, Andersen JS, Mann M, Terada N, Korsmeyer SJ 2001 p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD. Proc Natl Acad Sci USA 98:9666-9670
39. Hentges KE, Sirry B, Gingeras AC, Sarbassov D, Sonenberg N, Sabatini D, Peterson AS 2001 FRAP/mTOR is required for proliferation and patterning during embryonic development in the mouse. Proc Natl Acad Sci USA 98:13796-13801