Effects of synaptotagmin reveal two distinct mechanisms of agonist-stimulated internalization of the M4 muscarinic acetylcholine receptor

British Journal of Pharmacology

Volumn 144, Issue 6, 2005, Pages 761-771

  Madziva, Michel T ^a   Bai, Jihong ^b   Bhalla, Akhil ^b   Chapman, Edwin R ^b   Edwardson, J Michael ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

AP 2; Arrestin; Dynamin; Internalization; Muscarinic receptor; PIP 2; Synaptotagmin

Indexed keywords

ARRESTIN 2; DYNAMIN I; K 326327A; MUSCARINIC M4 RECEPTOR; MUTANT PROTEIN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPASE C; PHOSPHOLIPASE C DELTA1; RETINA S ANTIGEN; SYNAPTOTAGMIN; TRANSCRIPTION FACTOR AP 2; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CAVEOLA; CELL MEMBRANE; EMBRYO; ENDOCYTOSIS; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INTERNALIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION;

ADAPTOR PROTEIN COMPLEX 2; ARRESTINS; CALCIUM-BINDING PROTEINS; CELL CULTURE TECHNIQUES; CELL LINE; CELL MEMBRANE; DYNAMIN I; GREEN FLUORESCENT PROTEINS; HUMANS; ISOENZYMES; MEMBRANE GLYCOPROTEINS; MUSCARINIC AGONISTS; MUTATION; NERVE TISSUE PROTEINS; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHOLIPASE C; PROTEIN STRUCTURE, TERTIARY; RADIOLIGAND ASSAY; RECEPTORS, MUSCARINIC; SYNAPTOTAGMIN I; SYNAPTOTAGMINS; THYMIDINE; TRANSFECTION;

EID: 17144407633     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706035     Document Type: Article

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