Genomic organization of human arylamine N-acetyltransferase Type I reveals alternative promoters that generate different 5′-UTR splice variants with altered translational activities

Biochemical Journal

Volumn 387, Issue 1, 2005, Pages 119-127

  Butcher, Neville J ^a   Arulpragasam, Ajanthy ^b   Goh, Hui Li ^a   Davey, Tamara ^b   Minchin, Rodney F ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b NONE

Author keywords

5 untranslated region (5 UTR); Arylamine N transferase (NAT); N acetyltransferase; Promoter; Splice variant; Translation

Indexed keywords

BIOASSAY; PROTEINS; RNA; TISSUE;

EXON; GENOMIC ORGANIZATION; NON-CODING REGION; PROTEIN-CODING REGION;

GENES;

ARYLAMINE ACETYLTRANSFERASE; ARYLAMINE N ACETYLTRANSFERASE 1; LUCIFERASE; MESSENGER RNA; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

5' UNTRANSLATED REGION; ARTICLE; CAAT BOX; CANCER CELL CULTURE; CELL STRAIN HEPG2; CELL STRAIN HT29; CELL STRAIN MCF 7; CONSENSUS SEQUENCE; CONTROLLED STUDY; DNA STRUCTURE; EXON; EXPRESSED SEQUENCE TAG; GENE; GENE EXPRESSION; GENETIC ORGANIZATION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; NAT1 GENE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSLATION; SEQUENCE ANALYSIS; TATA BOX;

5' UNTRANSLATED REGIONS; ALTERNATIVE SPLICING; ARYLAMINE N-ACETYLTRANSFERASE; BREAST NEOPLASMS; CARCINOMA; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CLONING, MOLECULAR; EXONS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOME, HUMAN; HELA CELLS; HT29 CELLS; HUMANS; ISOENZYMES; JURKAT CELLS; LEUKEMIA, LYMPHOCYTIC; LIVER NEOPLASMS; LUNG NEOPLASMS; MELANOMA; PROMOTER REGIONS (GENETICS); PROTEIN BIOSYNTHESIS; VARIATION (GENETICS);

EID: 17144376746     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20040903     Document Type: Article

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