Identification of a minimal promoter sequence for the human N-acetyltransferase Type I gene that binds AP-1 (activator protein 1) and YY-1 (Yin and Yang 1)

Biochemical Journal

Volumn 376, Issue 2, 2003, Pages 441-448

  Butcher, Neville J ^a   Arulpragasam, Ajanthy ^a   Pope, Catherine ^a   Minchin, Rodney F ^a  

^a NONE

Author keywords

Activator protein 1 (AP 1); Gene induction; N acetyltransferase; Promoter; Transcription factor

Indexed keywords

ACETYLATION; AMINES; BIOASSAY; BLOOD; CATALYSIS; ENZYMES; GENES; RNA; TISSUE;

PROMOTER SEQUENCES;

BIOCHEMISTRY;

ACYLTRANSFERASE; AMINE; DNA; FOLIC ACID; HYDRAZINE; MESSENGER RNA; NUCLEAR PROTEIN; TRANSCRIPTION FACTOR AP 1;

ARTICLE; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; GENE; GENE CONTROL; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ACETYLTRANSFERASES; ARYLAMINE N-ACETYLTRANSFERASE; BASE SEQUENCE; BINDING SITES; CELL LINE; DNA-BINDING PROTEINS; ERYTHROID-SPECIFIC DNA-BINDING FACTORS; HUMANS; ISOENZYMES; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS; TRANSCRIPTION INITIATION SITE;

EID: 0348147581     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20030650     Document Type: Article

References (35)

1. Grant, D. M., Blum, M., Demierre, A. and Meyer, U. A. (1989) Nucleotide sequence of an intronless gene for a human arylamine N-acetyltransferase related to polymorphic drug acetylation. Nucleic Acids Res. 17, 3978
2. Blum, M., Grant, D. M., McBride, W., Heim, M. and Meyer, U. A. (1990) Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression. DNA Cell Biol. 9, 193-203
3. Hickman, D., Risch, A., Buckle, V., Spurr, N. K., Jeremiah, S. J., McCarthy, A. and Sim, E. (1994) Chromosomal localization of human genes for arylamine N-acetyltransferase. Biochem. J. 297, 441-445
4. Butcher, N. J., Boukouvala, S., Sim, E. and Minchin, R. F. (2002) Pharmacogenetics of the arylamine N-acetyltransferases. Pharmacogenomics J. 2, 30-42
5. Hein, D. W., Doll, M. A., Fretland, A. J., Leff, M. A., Webb, S. J., Xiao, G. H., Devanaboyina, U. S., Nangju, N. A. and Feng, Y. (2000) Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms. Cancer Epidemiol. Biomarkers Prev. 9, 29-42
6. Vatsis, K. P., Weber, W. W., Bell, D. A., Dupret, J. M., Evans, D. A., Grant, D. M., Hein, D. W., Lin, H. J., Meyer, U. A., Relling, M. V. et al. (1995) Nomenclature for N-acetyltransferases. Pharmacogenetics 5, 1-17
7. Hughes, N. C., Janezic, S. A., McQueen, K. L., Jewett, M. A., Castranio, T., Bell, D. A. and Grant, D. M. (1998) Identification and characterization of variant alleles of human acetyltransferase NAT1 with defective function using p-aminosalicylate as an in-vivo and in-vitro probe. Pharmacogenetics 8, 55-66
8. Lin, H. J., Probst-Hensch, N. M., Hughes, N. C., Sakamoto, G. T., Louie, A. D., Kau, I. H., Lin, B. K., Lee, D. B., Lin, J., Frankl, H. D. et al. (1998) Variants of N-acetyltransferase NAT1 and a case-control study of colorectal adenomas. Pharmacogenetics 8, 269-281
9. Butcher, N. J., Ilett, K. F. and Minchin, R. F. (1998) Functional polymorphism of the human arylamine N-acetyltransferase type 1 gene caused by C190T and G560A mutations. Pharmacogenetics 8, 67-72
10. Ward, A., Summers, M. J. and Sim, E. (1995) Purification of recombinant human N-acetyltransferase type 1 (NAT1) expressed in E. coli and characterization of its potential role in folate metabolism. Biochem. Pharmacol. 49, 1759-1767
11. Minchin, R. F. (1995) Acetylation of p-aminobenzoylglutamate, a folic acid catabolite, by recombinant human arylamine N-acetyltransferase and U937 cells. Biochem. J. 307, 1-3
12. Windmill, K. F., Gaedigk, A., Hall, P. M., Samaratunga, H., Grant, D. M. and McManus, M. E. (2000) Localization of N-acetyltransferases NAT1 and NAT2 in human tissues. Toxicol. Sci. 54, 19-29
13. Ohsako, S. and Deguchi, T. (1990) Cloning and expression of cDNAs for polymorphic and monomorphic arylamine N-acetyltransferases from human liver. J. Biol. Chem. 265, 4630-4634
14. Labarca, C. and Paigen, K. (1980) A simple, rapid, and sensitive DNA assay procedure. Anal. Biochem. 102, 344-352
15. Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254
16. Javahery, R., Khachi, A., Lo, K., Zenzie-Gregory, B. and Smale, S. T. (1994) DNA sequence requirements for transcriptional initiator activity in mammalian cells. Mol. Cell. Biol. 14, 116-127
17. Naora, H., van Leeuwen, B. H., Bourke, P. F. and Young, I. G. (1994) Functional role and signal-induced modulation of proteins recognizing the conserved TCATTT-containing promoter elements in the murine IL-5 and GM-CSF genes in T lymphocytes. J. Immunol. 153, 3466-3475
18. Nimer, S. D., Zhang, W., Kwan, K., Whang, Y. and Zhang, J. (1996) Adjacent, cooperative elements form a strong, constitutive enhancer in the human granulocyte-macrophage colony-stimulating factor gene. Blood 87, 3694-3703
19. Erratum (1996) Blood 88, 2818
20. Nimer, S., Fraser, J., Richards, J., Lynch, M. and Gasson, J. (1990) The repeated sequence CATT(A/T) is required for granulocyte-macrophage colony-stimulating factor promoter activity. Mol. Cell. Biol. 10, 6084-6088
21. Kaushansky, K., O'Rork, C., Shoemaker, S. G. and McCarty, J. (1996) The regulation of GM-CSF is dependent on a complex interplay of multiple nuclear proteins. Mol. Immunol. 33, 461-470
22. Ye, J., Zhang, X. and Dong, Z. (1996) Characterization of the human granulocyte-macrophage colony-stimulating factor gene promoter: an AP1 complex and an Sp1-related complex transactivate the promoter activity that is suppressed by a YY1 complex. Mol. Cell. Biol. 16, 157-167
23. Ye, J., Young, H. A., Ortaldo, J. R. and Ghosh, P. (1994) Identification of a DNA binding site for the nuclear factor YY1 in the human GM-CSF core promoter. Nucleic Acids Res. 22, 5672-5678
24. Bourke, P. F., van Leeuwen, B. H., Campbell, H. D. and Young, I. G. (1995) Localization of the inducible enhancer in the mouse interleukin-5 gene that is responsive to T-cell receptor stimulation. Blood 85, 2069-2077
25. Perrotti, D., Bellon, T., Trotta, R., Martinez, R. and Calabretta, B. (1996) A cell proliferation-dependent multiprotein complex NC-3A positively regulates the CD34 promoter via a TCATTT-containing element. Blood 88, 3336-3348
26. Lopez-Bayghen, E., Vega, A., Cadena, A., Granados, S. E., Jave, L. F., Gariglio, P. and Alvarez-Salas, L. M. (1996) Transcriptional analysis of the 5′-noncoding region of the human involucrin gene. J. Biol. Chem. 271, 512-520
27. Miller, C. P., Lin, J. C. and Habener, J. F. (1993) Transcription of the rat glucagon gene by the cyclic AMP response element-binding protein CREB is modulated by adjacent CREB-associated proteins. Mol. Cell. Biol. 13, 7080-7090
28. O'Connor, M. J., Tan, S. H., Tan, C. H. and Bernard, H. U. (1996) YY1 represses human papillomavirus type 16 transcription by quenching AP-1 activity. J. Virol. 70, 6529-6539
29. Herzig, T. C., Jobe, S. M., Aoki, H., Molkentin, J. D., Cowley, A. W., Jr., Izumo, S. and Markham, B. E. (1997) Angiotensin II type 1a receptor gene expression in the heart: AP-1 and GATA-4 participate in the response to pressure overload. Proc. Natl. Acad. Sci. U.S.A. 94, 7543-7548
30. Salton, S. R., Fischberg, D. J. and Dong, K. W. (1991) Structure of the gene encoding VGF, a nervous system-specific mRNA that is rapidly and selectively induced by nerve growth factor in PC12 cells. Mol. Cell. Biol. 11, 2335-2349
31. Estrada-Rodgers, L., Levy, G. N. and Weber, W. W. (1998) Characterization of a hormone response element in the mouse N-acetyltransferase 2 (Nat2*) promoter. Gene Expr. 7, 13-24
32. Mitchell, K. R. and Warshawsky, D. (2003) Xenobiotic inducible regions of the human arylamine N-acetyltransferase 1 and 2 genes. Toxicol. Lett. 139, 11-23
33. Sinclair, J. C., Sandy, J., Delgoda, R., Sim, E. and Noble, M. E. (2000) Structure of arylamine N-acetyltransferase reveals a catalytic triad. Nat. Struct. Biol. 7, 560-564
34. Sim, E., Payton, M., Noble, M. and Minchin, R. (2000) An update on genetic, structural and functional studies of arylamine N-acetyltransferases in eucaryotes and procaryotes. Hum. Mol. Genet. 9, 2435-2441
35. Butcher, N. J., Ilett, K. F. and Minchin, R. F. (2000) Substrate-dependent regulation of human arylamine N-acetyltransferase-1 in cultured cells. Mol. Pharmacol. 57, 468-473