Development of a microplate-based scintillation proximity assay for MraY using a modified substrate

Journal of Biomolecular Screening

Volumn 10, Issue 2, 2005, Pages 149-156

  Solapure, S M ^a   Raphael, P ^b   Gayathri, C N ^a   Barde, S P ^a   Chandrakala, B ^a   Das, K S ^a   DeSousa, S M ^a  

^a ASTRAZENECA   (United Kingdom)

^b NONE

Author keywords

Antibacterial; HTS; Modified substrate; MraY; Scintillation proximity assay

Indexed keywords

BACTERIAL ENZYME; CARRIER PROTEIN; ENZYME INHIBITOR; PENTAPEPTIDE; PEPTIDOGLYCAN; PROTEIN MRAY; RADIOISOTOPE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE N ACETYLMURAMIC ACID; URIDINE DIPHOSPHATE N ACETYLMURAMIC ACID PENTAPEPTIDE; WHEAT GERM AGGLUTININ;

ARTICLE; BACTERIAL MEMBRANE; ENZYME ASSAY; ENZYME INHIBITION; ESCHERICHIA COLI; HIGH THROUGHPUT SCREENING; INTERMETHOD COMPARISON; ISOTOPE LABELING; NONHUMAN; PAPER CHROMATOGRAPHY; PRIORITY JOURNAL; SCINTILLATION; SCINTILLATION PROXIMITY ASSAY; VALIDATION PROCESS;

BACTERIAL PROTEINS; MONOSACCHARIDES; MURAMIC ACIDS; OLIGOPEPTIDES; PEPTIDES; PEPTIDOGLYCAN; PROPIONATES; SCINTILLATION COUNTING; SUBSTRATE SPECIFICITY; TRANSFERASES; URIDINE DIPHOSPHATE;

ESCHERICHIA COLI; TRITICUM AESTIVUM;

EID: 17044391352     PISSN: 10870571     EISSN: None     Source Type: Journal    
DOI: 10.1177/1087057104272007     Document Type: Article

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