Polymorphisms in genes involved in xenobiotic metabolism and lung cancer risk under the age of 60 years: A pooled study of lung cancer patients in Denmark and Norway

Lung Cancer

Volumn 48, Issue 2, 2005, Pages 187-199

  Skuladottir, Halla ^a   Autrup, Herman ^b   Autrup, Judith ^b   Tjoenneland, Anne ^a   Overvad, Kim ^b,c   Ryberg, David ^d   Haugen, Aage ^d   Olsen, Jørgen H ^a  

^a INSTITUTE OF CANCER EPIDEMIOLOGY   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

^c AALBORG UNIVERSITY HOSPITAL   (Denmark)

^d NATIONAL INSTITUTE OF OCCUPATIONAL HEALTH   (Norway)

Author keywords

Age; Metabolic polymorphisms; Non small cell lung cancer; Smoking; Young onset

Indexed keywords

ARYLAMINE ACETYLTRANSFERASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE PEROXIDASE 1; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE M3; GLUTATHIONE TRANSFERASE P1; GLUTATHIONE TRANSFERASE T1; MYELOPEROXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); UNCLASSIFIED DRUG;

ADULT; ALLELE; ARTICLE; CANCER PATIENT; CANCER RISK; CONTROLLED STUDY; DEMOGRAPHY; DENMARK; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; GROUPS BY AGE; HETEROZYGOTE; HIGH RISK PATIENT; HUMAN; HUMAN CELL; LIFESTYLE; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; NORWAY; PHENOTYPE; PRIORITY JOURNAL; QUESTIONNAIRE; RISK ASSESSMENT; SMOKING; STATISTICAL SIGNIFICANCE; XENOBIOTIC METABOLISM;

EID: 17044375448     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2004.10.013     Document Type: Article

References (72)

1. P. Lichtenstein, N.V. Holm, P.K. Verkasalo, A. Iliadou, J. Kaprio, and M. Koskenvuo Environmental and heritable factors in the causation of cancer-analyses of cohorts of twins from Sweden, Denmark, and Finland N Engl J Med 343 2000 78 85
2. J.H. Olsen, A. Andersen, L. Dreyer, E. Pukkala, L. Tryggvadottir, and M.G. deVerdier Causes of cancer in the Nordic contries APMIS 105 Suppl. 76 1997 1 146
3. P. Vineis, N. Caporaso, J. Cuzick, M. Lang, N. Malats, and P. Boffetta Genetic susceptibility to cancer: metabolic polymorphisms. IARC Scientific Publication No. 148 1999 International Agency for Research on Cancer Lyon
4. S.T. Bogardus, J. Concato, and A.R. Feinstein Clinical epidemiological quality in molecular genetic research. The need for methodological standards JAMA 281 1999 1919 1926
5. J.D. Hayes, and D.J. Pulford The glutathone S-transferase supergene family: regulation of GST* and the contribution of the isozymes to cancer chemoprotection and drug resistance Crit Rev Biochem Mol Biol 30 1995 445 600
6. S. Garte, L. Gaspari, A.-K. Alexandrie, C. Ambrosone, H. Autrup, and J.L. Autrup Metabolic gene polymorphism frequencies in control populations Cancer Epidemiol Biomarkers Prev 10 2001 1239 1248
7. F. Ali-Osman, O. Akande, G. Antoun, J.X. Mao, and J. Buolamwini Molecular cloning, characterization, and expression in Escherichia coli of full-length cDNAs of three human glutathione S-transferase Pi gene variants. Evidence for differential catalytic activity of the encoded proteins J Biol Chem 272 1997 10004 10012
8. A. Inskip, J. Elexperu-Camiruaga, N. Buxton, P.S. Dias, J. MacIntosh, and D. Campbell Identification of polymorphism at the glutathione S-transferase GSTM3 locus: evidence for linkage with GSTM1*A Biochem J 312 1995 713 716
9. V. Jahnke, R. Strange, C. Matthias, and A. Fryer Glutathione S-transferase and cytochrome P450 genotypes as risk factors for laryngeal carcinoma Eur Arch Otorhinolaryngol 254 Suppl. 1 1997 147 149
10. Y. Shi, J.S. Lee, and K.M. Galvin Everything you have ever wanted to know about Yin Yang 1 Biochim Biophys Acta 1332 1997 49 66
11. S. Anttila, A. Hirvonen, H. Vainio, K. Husgafvel-Pursiainen, J.D. Hayes, and B. Ketterer Immunohistochemical localization of glutathione S-transferases in human lung Cancer Res 53 1993 5643 5648
12. T. Nakajima, E. Elovaara, S. Anttila, A. Hirvonen, A.M. Camus, and J.D. Hayes Expression and polymorphism of glutathione S-transferase in human lungs: risk factors in smoking-related lung cancer Carcinogenesis 16 1995 707 711
13. A.M. Cantlay, C.A. Smith, W.A. Wallace, P.L. Yap, D. Lamb, and D.J. Harrison Heterogeneous expression and polymorphic genotype of glutathione S-transferases in human lung Thorax 49 1994 1010 1014
14. G.M. Lower, T. Nilsson, C.E. Nelson, H. Wolf, T.E. Gamsky, and G.T. Bryan N-acetyltransferase phenotype and risk in urinary bladder cancer: approaches in molecular epidemiology. Preliminary results in Sweden and Denmark Environ Health Perspect 29 1979 71 79
15. I. Cascorbi, J. Brockmöller, P.M. Mrozikiewicz, S. Bauer, R. Loddemkemper, and L. Roots Homozygous rapid arylamine N-acetyltransferase (NAT2) genotype as a susceptibility factor for lung cancer Cancer Res 56 1996 3961 3966
16. H. Okkels, T. Sigsgaard, H. Wolf, and H. Autrup Arylamine N-acetyltransferase 1 (NAT1), and 2 (NAT2) polymorphisms in susceptibility to bladder cancer: the influence of smoking Cancer Epidemiol Biomark Prev 6 1997 225 231
17. J.M. Petruska, D.R. Mosebrook, G.J. Jakab, and M.A. Trush Myeloperoxidase-enhanced formation of (_)-trans-7,8-dihydroxy-7,8- dihydrobenzo(a)pyrene-DNA adducts in lung tissue in vitro: a role of pulmonary inflammation in the bioactivation of a procarcinogen Carcinogenesis 13 1992 1075 1081
18. J.S. London Myeloperoxidase genetic polymorphism and lung cancer risk Cancer Res 57 1997 5001 5003
19. M.B. Schabath, M.R. Spitz, W.K. Hong, G.L. Delclos, W.F. Reynolds, and G.B. Gunn A myeloperoxidase polymorphism associated with reduced risk of lung cancer Lung Cancer 37 2002 35 40
20. J.A. Moscow, L. Schmidt, D.T. Ingram, J. Gnarra, B. Johnson, and K.H. Cowan Loss of heterozygosity of the human cytosolic glutathione peroxidase I gene in lung cancer Carcinogenesis (Lond.) 15 1994 2769 2773
21. D. Ratnasinghe, J.A. Tangrea, M.R. Andersen, M.J. Barrett, J. Virtamo, and P.R. Taylor Glutathione peroxidase codon 198 polymorphism variant increases lung cancer risk Cancer Res 60 2000 6381 6383
22. J.K. Wiencke, Mr Spitz, A. McMillan, and K.T. Kelsye Lung cancer on mexican-americans and african-americans is associated with the wild-type genotype of the NAD(P)H:quinone Odidoreductase polymorphism Cancer Epi Biol Prev 6 1997 87 98
23. Y.J. Hu, and A.M. Diamond Role of glutathione peroxidase 1 in breast cancer: loss of heterozygosity and allelic differences in the response to selenium Cancer Res 63 2003 3347 3351
24. S. Benhamou, W.J. Lee, A.K. Alexandrie, P. Boffetta, C. Bouchardy, and D. Butkiewicz Meta- and pooled analyses of the effects of glutathione S-transferase M1 polymorphisms and smoking on lung cancer risk Carcinogenesis 23 2002 1343 1350
25. I. Stucker, A. Hirvonen, I. de Waziers, A. Cabelguenne, K. Mitrunen, and S. Cenee Genetic polymorphisms of glutathione S-transferases as modulators of lung cancer susceptibility Carcinogenesis 23 2002 1475 1481
26. C. Kiyohara, A. Otsu, T. Shirakawa, S. Fukuda, and J.M. Hopkin Genetic polymorphisms and lung cancer susceptibility: a review Lung Cancer 37 2002 241 256
27. K.M. Smits, S. Benhamou, S. Garte, M.P. Weijenberg, Y. Alamanos, and C. Ambrosone Association of metabolic gene polymorphisms with tobacco consumption in healthy controls Int J Cancer 110 2004 266 270
28. M. Sorensen, H. Autrup, A. Tjonneland, K. Overvad, and O. Raaschou-Nielsen Glutathione S-transferase T1 null-genotype is associated with an increased risk of lung cancer Int J Cancer 110 2004 219 224
29. D. Ryberg, V. Skaug, A. Hewer, D.H. Phillips, L.W. Harries, and C.R. Wolf Genotypes of glutathione transferase M1 and P1 and their significance for lung DNA adduct levels and cancer risk Carcinogenesis 18 1997 1285 1289
30. S.M. Hou, D. Ryberg, S. Falt, A. Deverill, T. Tefre, and A.L. Borresen GSTM1 and NAT2 polymorphisms in operable and non-operable lung cancer patients Carcinogenesis 21 2000 49 54
31. S. Zhong, A.F. Howie, B. Ketterer, J. Taylor, J.D. Hayes, and G.J. Beckett Glutathione S-transferase mu locus: use of genotypning and phenotyping assays to assess association with lung cancer susceptibility Carcinogenesis 12 1991 1533 1537
32. L.W. Harries, M.J. Stubbins, D. Forman, G.C. Howard, and C.R. Wolf Identification of genetic polymorphisms at the glutathione S-transferase Pi locus and association with susceptibility to bladder, testicular and prostate cancer Carcinogenesis 18 1997 641 644
33. S. Pemble, K.R. Schroeder, S.R. Spencer, D.J. Meyer, E. Hallier, and H.M. Bolt Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism Biochem J 300 1994 271 276
34. A. Risch, H. Wikman, S. Thiel, P. Schmezer, L. Edler, and P. Drings Glutathione-S-transferase M1, M3, T1 and P1 polymorphisms and susceptibility to non-small-cell lung cancer subtypes and hamartomas Pharmacogenetics 11 2001 757 764
35. S.J. Lewis, N.M. Cherry, R.M. Niven, P.V. Barber, and A.C. Povey GSTM1, GSTT1 and GSTP1 polymorphisms and lung cancer risk Cancer Lett 180 2002 165 171
36. F.P. Perera, L.A. Mooney, M. Stampfer, D.H. Phillips, D.A. Bell, and A. Rundle Physicians' Health Cohort Study. Associations between carcinogen-DNA damage, glutathione S-transferase genotypes, and risk of lung cancer in the prospective Physicians' Health Cohort Study Carcinogenesis 23 2002 1641 1646
37. D.P. Miller, I. De Vivo, D. Neuberg, J.C. Wain, T.J. Lynch, and L. Su Association between self-reported environmental tobacco smoke exposure and lung cancer: modification by GSTP1 polymorphism Int J Cancer 104 2003 758 763
38. Y. Wang, M.R. Spitz, M.B. Schabath, F. Ali-Osman, H. Mata, and X. Wu Association between glutathione S-transferase p1 polymorphisms and lung cancer risk in Caucasians: a case-control study Lung Cancer 40 2003 25 32
39. V. Nazar-Stewart, T.L. Vaughan, P. Stapleton, J. Van Loo, B. Nicol-Blades, and D.L. Eaton A population-based study of glutathione S-transferase M1, T1 and P1 genotypes and risk for lung cancer Lung Cancer 40 2003 247 258
40. K.T. Kelsey, M.R. Spitz, Z.F. Zuo, and J.K. Wiencke Polymorphisms in the glutathione S-transferase class mu and theta genes interact and increase susceptibility to lung cancer in minority populations (Texas, United States) Cancer Causes Contr 8 1997 554 559
41. S.T. Saarikoski, A. Voho, M. Reinikainen, S. Anttila, A. Karjalainen, and C. Malaveille Combined effect of polymorphic GST genes on individual susceptibility to lung cancer Int J Cancer 77 1998 516 521
42. J. Salagovic, I. Kalina, J. Stubna, V. Habalova, M. Hrivnak, and L. Valansky Genetic polymorphism of glutathione S-transferases M1 and T1 as a risk factor in lung and bladder cancers Neoplasma 45 1998 312 317
43. C. Kiyohara, K.I. Yamamura, Y. Nakanishi, K. Takayama, and N. Hara Polymorphism in GSTM1, GSTT1, and GSTP1 and susceptibility to lung cancer in a Japanese population Asian Pac J Cancer Prev 1 2000 293 298
44. N. Malats, A.M. Camus-Radon, F. Nyberg, W. Ahrens, V. Constantinescu, and A. Mukeria Lung cancer risk in nonsmokers and GSTM1 and GSTT1 genetic polymorphism Cancer Epidemiol Biomarkers Prev 9 2000 827 833
45. S.M. Hou, S. Falt, and F. Nyberg Glutathione S-transferase T1-null genotype interacts synergistically with heavy smoking on lung cancer risk Environ Mol Mutagen 38 2001 83 86
46. A. Sgambato, B. Campisi, A. Zupa, A. Bochicchio, G. Romano, and A. Tartarone Glutathione S-transferase (GST) polymorphisms as risk factors for cancer in a highly homogeneous population from southern Italy Anticancer Res 22 2002 3647 3652
47. E. Taioli, L. Gaspari, S. Benhamou, P. Boffetta, J. Brockmoller, and D. Butkiewicz Polymorphisms in CYP1A1, GSTM1, GSTT1 and lung cancer below the age of 45 years Int J Epidemiol 32 2003 60 63
48. J. Wang, Y. Deng, J. Cheng, J. Ding, and S. Tokudome GST genetic polymorphisms and lung adenocarcinoma susceptibility in a Chinese population Cancer Lett 201 2003 185 193
49. I.A. Dialyna, S. Miyakis, N. Georgatou, and D.A. Spandidos Genetic polymorphisms of CYP1A1, GSTM1 and GSTT1 genes and lung cancer risk Oncol Rep 10 2003 1829 1835
50. A.K. Alexandrie, F. Nyberg, M. Warholm, and A. Rannug Influence of CYP1A1, GSTM1, GSTT1, and NQO1 genotypes and cumulative smoking dose on lung cancer risk in a Swedish population Cancer Epidemiol Biomarkers Prev 13 2004 908 914
51. J. To-Figueras, M. Gene, J. Gomez-Catalan, M.C. Galan, M. Fuentes, and J.M. Ramon Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) polymorphisms and lung cancer risk among Northwestern Mediterraneans Carcinogenesis 18 1997 1529 1533
52. R. el-Zein, J.B. Zwischenberger, T.G. Wood, S.Z. Abdel-Rahman, C. Brekelbaum, and W.W. Au Combined genetic polymorphism and risk for development of lung cancer Mutat Res 381 1997 189 200
53. N. Sunaga, T. Kohno, N. Yanagitani, H. Sugimura, H. Kunitoh, and T. Tamura Contribution of the NQO1 and GSTT1 polymorphisms to lung adenocarcinoma susceptibility Cancer Epidemiol Biomarkers Prev 11 2002 730 738
54. D. Ratnasinghe, J.A. Tangrea, M.R. Andersen, M.J. Barrett, J. Virtamo, and P.R. Taylor Glutathione peroxidase codon 198 polymorphism variant increases lung cancer risk Cancer Res 60 2000 6381 6383
55. C. Martinez, Agundez JAG, M. Olivera, R. Martin, J.M. Ladero, and J. Benitez Lung cancer and mutations at the polymorphic NAT2 gene locus Pharmacogenetics 5 1995 207 214
56. C. Bouchardy, K. Mitrunen, H. Wikman, K. Husgafvel-Pursiainen, P. Dayer, and S. Benhamou N-acetyltransferase NAT1 and NAT2 genotypes and lung cancer risk Pharmacogenetics 8 1998 291 298
57. S.T. Saarikoski, M. Reinikainen, S. Anttila, A. Karjalainen, H. Vainio, and K. Husgafvel-Pursiainen Role of NAT2 deficiency in susceptibility to lung cancer among asbestos-exposed individuals Pharmacogenetics 10 2000 183 185
58. T. Oyama, T. Kawamoto, T. Mizoue, K. Yasumoto, Y. Kodama, and T. Mitsudomi N-acetylation polymorphism in patients with lung cancer and its association with p53 gene mutation Anticancer Res 17 1997 577 582
59. A. Seow, B. Zhao, W.T. Poh, M. The, P. Eng, and Y.T. Wang NAT2 slow acetylator genotype is associated with increased risk of lung cancer among non-smoking Chinese women in Singapore Carcinogenesis (Lond.) 20 1999 1877 1881
60. S.M. Hou, D. Ryberg, S. Falt, A. Deverill, T. Tefre, and A.L. Borresen GSTM1 and NAT2 polymorphisms in operable and non-operable lung cancer patients Carcinogenesis (Lond.) 21 2000 49 54
61. F. Nyberg, S.M. Hou, K. Hemminki, B. Lambert, and G. Pershagen Glutathione S-transferase μ1 and N-acetyltransferase 2 genetic polymorphisms and exposure to tobacco smoke in nonsmoking and smoking lung cancer patients and population controls Cancer Epidemiol Biomark Prev 7 1998 875 883
62. W. Zhou, G. Liu, S.W. Thurston, L.L. Xu, D.P. Miller, and J.C. Wain Genetic Polymorphisms in N-acetyltransferase-2 and microsomal epoxide hydrolase, cumulative cigarette smoking, and lung cancer Cancer Epidemiol Biomark Prev 11 2002 15 21
63. D. Siegel, S.M. McGuinnes, S.L. Winski, and D. Ross Genotype-phenotype relationships in studies of a polymorphism in NAD(P)H:quinone oxireductase Pharmacogenetics 9 1999 113 121
64. L.L. Xu, J.C. Wain, D.P. Miller, S.W. Thurston, L. Su, and T.J. Lynch The NAD(P)H:quinone Oxidoreductase 1 Gene Polymorphism and Lung Cancer. Differential Susceptibility Based on Smoking Behavior Cancer Epidemiol Biomark Prev 10 2001 303 309
65. (463G → a polymorphism does not decrease lung cancer susceptibility in caucasians Cancer Epidemiol Biomarkers Prev 11 2002 1555 1559
66. M.B. Schabath, M.R. Spitz, G.L. Delclos, G.B. Gunn, L.W. Whitehead, and W.X. Wu Association between asbestos exposure, cigarette smoking, myeloperoxidase (MPO) genotypes, and lung cancer risk Am J Ind Med 42 2002 29 37
67. W. Lu, D. Xing, J. Qi, W. Tan, X. Miao, and D. Lin Genetic polymorphism in myeloperoxidase but not GSTM1 is associated with risk of lung squamous cell carcinoma in a Chinese population Int J Cancer 102 2002 275 279
68. I. Goto, S. Yoneda, M. Yamamoto, and K. Kawajiri Prognostic significance of germ line polymorphisms of the CYP1A1 and glutathione S-transferase genes in patients with non-small cell lung cancer Cancer Res 56 1996 3725 3730
69. H. Ge, W.K. Lam, J. Lee, M.P. Wong, W.W. Yew, and M.L. Lung Analysis of l-myc and GSTM1 genotypes in Chinese non-small cell lung carcinoma patients Lung Cancer 15 1996 355 366
70. R.M. Przygodzki, W.P. Bennett, D.G. Guinee Jr., M.A. Khan, A. Freedman, and P.G. Shields p53 Mutation spectrum in relation to GSTM1, CYP1A1 and CYP2E1 in surgically treated patients with non-small cell lung cancer Pharmacogenetics 8 1998 503 511
71. P. Yang, A. Yokomizo, H.D. Tazelaar, R.S. Marks, T.G. Lesnick, and D.L. Miller Genetic determinants of lung cancer short-term survival: the role of glutathione-related genes Lung Cancer 35 2002 221 229
72. C. Sweeney, V. Nazar-Stewart, P.L. Stapleton, D.L. Eaton, and T.L. Vaughan Glutathione S-transferase M1, T1, and P1 polymorphisms and survival among lung cancer patients Cancer Epidemiol Biomarkers Prev 12 2003 527 533