Glutathione S-transferase μ1 and N-acetyltransferase 2 genetic polymorphisms and exposure to tobacco smoke in nonsmoking and smoking lung cancer patients and population controls

Cancer Epidemiology Biomarkers and Prevention

Volumn 7, Issue 10, 1998, Pages 875-883

  Nyberg, Fredrik ^a   Hou, Sai Mei ^a   Hemminki, Kari ^a   Lambert, Bo ^a   Pershagen, Göran ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; GLUTATHIONE TRANSFERASE; TOBACCO SMOKE;

ACETYLATION; ADULT; AGED; ARTICLE; CANCER RISK; CASE CONTROL STUDY; CONTROLLED STUDY; FEMALE; GENE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SMOKING; THORAX RADIOGRAPHY;

ACETYLATION; ADULT; AGED; AGED, 80 AND OVER; ARYLAMINE N-ACETYLTRANSFERASE; CASE-CONTROL STUDIES; FEMALE; GENOTYPE; GLUTATHIONE TRANSFERASE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; ODDS RATIO; POLYMORPHISM, GENETIC; QUESTIONNAIRES; RISK FACTORS; SMOKING; SWEDEN; TIME FACTORS;

EID: 0031707010     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Law, M. R. Genetic predisposition to lung cancer Br. J. Cancer, 61: 195-206, 1990.
2. McWilliams, J. E., Sanderson, B. J., Harris, E. L., Richert-Boe, K. E., and Henner, W. D. Glutathione S-transferase M1 (GSTM1) deficiency and lung cancer risk. Cancer Epidemiol. Biomark Prev., 4: 589-594, 1995
3. Katoh, T. The frequency of glutathione-S-transferase M1 (GSTM1) gene deletion in patients with lung and oral cancer [in Japanese]. Sangyo. Igaku., 36: 435-439, 1994.
4. Kihara, M., and Noda, K. Distribution of GSTM1 null genotype in relation to gender, age and smoking status in Japanese lung cancer patients. Pharmacogenetics, 5: S74-S79, 1995.
5. Kihara, M., and Noda, K. Risk of smoking for squamous and small cell carcinomas of the lung modulated by combinations of CYPIA1 and GSTM1 gene polymorphisms in a Japanese population. Carcinogenesis (Lond.), 16: 2331-2336, 1995
6. London, S. J., Daly, A. K., Cooper, J., Navidi, W. C., Carpenter, C. L., and Idle, J. R. Polymorphism of glutathione S-transferase M1 and lung cancer risk among African-Americans and Caucasians in Los Angeles County, California. J. Natl. Cancer Inst. (Bethesda), 87: 1246-1253, 1995.
7. Deakin, M., Elder, J., Hendrickse, C., Peckham, D., Baldwin, D., Pantin, C., Wild, N., Leopard, P., Bell, D. A., Jones, P., Duncan, H., Brannigan, K., Alldersea, J., Fryer, A. A., and Strange, R. C. Glutathione S-transferase GSTT1 genotypes and susceptibility to cancer: studies of interactions with GSTM1 in lung, oral, gastric and colorectal cancers. Carcinogenesis (Lond.), 17: 881-884, 1996.
8. Moreira, A., Martins, G., Monteiro, M. J., Alves, M., Dias, J., da Costa, J. D., Melo, M. J., Matias, D., Costa, A., Cristovao, M., Rueff, J., and Monteiro, C. Glutathione S-transferase μ polymorphism and susceptibility to lung cancer in the Portuguese population. Teratog. Carcinog, Mutagen., 16: 269-274, 1996
9. To-Figueras, J., Gene, M., Gomez-Catalan, J., Galan, C., Firvida, J., Fuentes, M., Rodamilans, M., Huguet, E., Estape, J., and Corbella, J. Glutathione-S-transferase M1 and codon 72 p53 polymorphisms in a northwestern Mediterranean population and their relation to lung cancer susceptibility Cancer Epidemiol. Biomark. Prev., 5: 337-342, 1996.
10. El-Zein, R. A., Zwischenberger, J. B., Abdel-Rahman, S. Z., Sankar, A. B., and Au, W. W. Polymorphism of metabolizing genes and lung cancer histology: prevalence of CYP2E1 in adenocarcinoma. Cancer Lett., 112: 71-78, 1997.
11. Garcia-Closas, M., Kelsey, K. T., Wiencke, J. K., Xu, X. P., Wain, J. C., and Christiani, D. C. A case-control study of cytochrome P450 IA1, glutathione S-transferase M1, cigarette smoking and lung cancer susceptibility (Massachusetts, United States) Cancer Causes Control, 8: 544-553, 1997.
12. Kelsey, K. T., Spitz, M. R., Zuo, Z. F., and Wiencke, J. K. Polymorphisms in the glutathione S-transferase class μ and θ genes interact and increase susceptibility to lung cancer in minority populations (Texas, United States). Cancer Causes Control, 8: 554-559, 1997.
13. Sun, G. F., Shimojo, N., Pi, J. B., Lee, S., and Kumagai, Y. Gene deficiency of glutathione S-transferase μ isoform associated with susceptibility to lung cancer in a Chinese population. Cancer Lett, 113: 169-172, 1997.
14. Risch, A., Wallace, D. M., Bathers, S., and Sim, E. Slow N-acetylation genotype is a susceptibility factor in occupational and smoking related bladder cancer. Hum Mol Genet., 4: 231-236, 1995.
15. Brockmoller, J., Cascorbi, I., Kerb, R., and Roots, I. Combined analysis of inherited polymorphisms in arytamine N-acetyltransferase 2, glutathione S-transferases MI and TI, microsomal epoxide hydrolase, and cytochrome P450 enzymes as modulators of bladder cancer risk. Cancer Res., 56: 3915-3925, 1996.
16. Okkels, H., Sigsgaard, T, Wolf, H., and Autrup, H. Arylamine N-acetyl-transferase 1 (NAT1) and 2 (NAT2) polymorphisms in susceptibility to bladder cancer the influence of smoking. Cancer Epidemiol. Biomark Prev., 6: 225-231, 1997.
17. Ambrosone, C. B., Freudenheim, J. L., Graham, S., Marshall, J. R., Vena, J. E., Brasure, J. R., Michalek, A. M., Laughlin, R., Nemoto, T., Gillenwater, K. A., and Shields, P. G. Cigarette smoking, N-acetyltransferase 2 genetic polymorphisms, and breast cancer risk. J. Am. Med. Assoc., 276: 1494-1501, 1996.
18. Minchin, R. F., Kadlubar, F. F., and Ilett, K. F. Role of acetylation in colorectal cancer Mutat. Res., 290: 35-42, 1993.
19. Lang, N. P., and Kadlubar, F. F. Aromatic and heterocyclic amine metabolism and phenotyping in humans. Prog. Clin. Biol Res., 372: 33-47, 1991.
20. Cofta, S., Lowicki, Z., and Mlynarczyk, W. Fenotyp acetylacji u chorych na raka pluca [in Polish]. Pneumonol. Alesrgol. Polska, 63: 407-409, 1995.
21. Oyama, T., Kawamoto, T., Mizouc, T., Yasumoto, K., Kodama, Y., and Mitsudomi, T. N-Acetylation polymorphism in patients with lung cancer and its association with p53 gene mutation. Anticancer Res., 17: 577-581, 1997
22. Burgess, E. J., and Trafford, J. A. P. Acetylator phenotype in patients with lung carcinoma: a negative report. Eur J Respir Dis., 67: 17-19, 1985.
23. Philip, P. A., Fitzgerald, D. L., Cartwright, R. A., Peake, M. D., and Rogers, H. J. Polymorphic N-acetylation capacity in lung cancer. Carcinogenesis (Lond.), 9: 491-493, 1988.
24. Roots, I., Drakoulis, N., Ploch, M., Heinemeyer, G., Loddenkemper, R., Minks, T., Nitz, M., Otte, F., and Koch, M. Debrisoquine hydroxylation phenotype, acetylation phenotype, and ABO blood groups as genetic host factors of lung cancer risk. Klin Wochenschr., 66 (Suppl. 11): 87-97, 1988.
25. Laredo Quesada, J. M., Jara Sanchez, C., Benitez Rodriguez, J., Fernandez Gundin, M. J., Vargas Castrillon, E., Munoz Gonzalez, J. J., Llerena Ruiz, A., Cobaleda Polo, J., and Perez-Manga, G. Polimorfismo acetilador en el cáncer de pulmón [in Spanish]. Ann Med Intern., 8: 66-68, 1991
26. Martinez, C., Agundez, J. A., Olivera, M., Martin, R., Ladero, J. M., and Benitez, J. Lung cancer and mutations at the polymorphic NAT2 gene locus. Pharmacogenetics. 5: 207-214, 1995.
27. Cascorbi, I., Brockmoller, J., Mrozikiewicz, P. M., Bauer, S., Loddenkemper, R., and Roots, I. Homozygous rapid arylamine N-acetyltransferase (NAT2) genotype as a susceptibility factor for lung cancer. Cancer Res , 56: 3961-3966, 1996.
28. Hein, D. W., Doll, M. A., Rustan, T. D., Gray, K., Feng, Y., Ferguson, R. J., and Grant, D. M. Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases. Carcinogenesis (Lond.), 14: 1633-1638, 1993.
29. Wild, D., Feser, W., Michel, S., Lord, H. L., and Josephy, P. D. Metabolic activation of heterocyclic aromatic amines catalyzed by human arylamine N-acetyltransferase isozymes (NAT1 and NAT2) expressed in Salmonella typhimurium Carcinogenesis (Lond.), 16: 643-648, 1995.
30. Nyberg, F., Agrenius, V., Svartengren, K., Svensson, C., and Pershagen, G. Environmental tobacco smoke and lung cancer in nonsmokers: does time since exposure play a role? Epidemiology, 9: 301-308, 1998.
31. WHO. The World Health Organization histological typing of lung tumors, second edition. Am. J. Clin. Pathol., 77: 123-136, 1982.
32. Riboli, E., Preston-Martin, S., Saracci, R., Haley, N. J., Trichopoulos, D., Becher, H., Burch, J. D., Fontham, E. T., Gao, Y. T., Jindal, S. K., Koo, L. C., Le Marchand, L., Segnan, N., Shimizu, H., Stanta, G., Wu-Williams, A. H., and Zatonski, W. Exposure of nonsmoking women to environmental tobacco smoke: a 10-country collaborative study. Cancer Causes Control, I: 243-252, 1990.
33. Boffetta, P., Kogevinas, M., Simonato, L., Wilboum, J., and Saracci, R. Current perspectives on occupational cancer. Int J. Occup. Environ. Health, 1: 315-325, 1995.
34. WHO. World Health Organization International Standard Code for Occupations. Geneva WHO, 1968
35. WHO. World Health Organization International Standard Industrial Code. Geneva: WHO, 1971.
36. Andersson, B., Hou, S. M., and Lambert, B. Mutations causing defective splicing in the human hprt gene. Environ. Mol. Mutagen., 20: 89-95, 1992.
37. Hou, S. M., Lambert, B., and Hemminki, K. Relationship between hprt mutant frequency, aromatic DNA adducts and genotypes for GSTM1 and NAT2 in bus maintenance workers Carcinogenesis (Lond), 16: 1913-1917, 1995.
38. Hein, D. W., Doll, M. A., Rustan, T. D., and Ferguson, R. J. Metabolic activation of N-hydroxyarylamines and N-hydroxyarylamides by 16 recombinant human NAT2 allozymes: effects of seven specific NAT2 nucleic acid substitutions. Cancer Res., 55: 3531-3536, 1995.
39. Breslow, N. E., and Day, N. E. Statistical Methods in Cancer Research. The Analysis of Case-Control Studies. Vol. 1. Lyon: IARC, 1980.
40. Pearce, N. What does the odds ratio estimate in a case-control study? Int. J Epidemiol., 22: 1189-1192, 1993.
41. Pearce, N., and Boffetta, P. General Issues of Study Design and Analysis in the Use of Biomarkers in Cancer Epidemiology. IARC Sci. Publ., 142: 47-57, 1997.
42. Nyberg, F., Agudo, A., Boffetta, P., Fortes, C., Gonzalez, C. A., and Pershagen, G. A. European validation study of smoking and environmental tobacco smoke exposure in non-smoking lung cancer cases and controls. Cancer Causes Control, 9: 173-182, 1998.
43. Svensson, C. Lung cancer etiology in women (Doctoral Thesis). Stockholm: Karulinska Institute, 1988.
44. Alexandrie, A. K., Sundberg, M. I., Seidegard, J., Tornling, G., and Rannug, A. Genetic susceptibility to lung cancer with special emphasis on CYP1A1 and GSTM1: a study on host factors in relation to age at onset, gender and histological cancer types. Carcinogenesis (Lond.), 15: 1785-1790, 1994.
45. Lin, H. J., Han, C. Y., Bernstein, D. A., Hsiao, W., Lin, B. K., and Hardy, S. Ethnic distribution of the glutathione transferase μ 1-1 (GSTM1) null genotype in 1473 individuals and application to bladder cancer susceptibility. Carcinogenesis (Lond.), 15: 1077-1081, 1994.
46. Mikelsaar, A. V., Tasa, G., Parlist, P., and Uuskula, M. Human glutathione S-transferase GSTM1 genetic polymorphism in Estonia. Hum. Hered., 44: 248-251, 1994.
47. Heckbert, S. R., Weiss, N. S., Hornung, S. K., Eaton, D. L., and Motulsky, A. G. Glutathione S-transferase and epoxide hydrolase activity in human leukocytes in relation to risk of lung cancer and other smoking-related cancers J. Natl. Cancer Inst (Bethesda), 84: 414-422, 1992.
48. Hirvonen, A., Husgafvel-Pursiainen, K., Anttila, S., and Vainio, H. The GSTM1 null genotype as a potential risk modifier for squamous cell carcinoma of the lung. Carcinogenesis (Lond.), 14: 1479-1481, 1993.
49. Kihara, M., and Noda, K. Lung cancer risk of GSTM1 null genotype is dependent on the extent of tobacco smoke exposure. Carcinogenesis (Lond.), 15: 415-418, 1994.
50. Nazar-Stewart, V., Motulsky, A. G., Eaton, D. L., White, E., Hornung, S. K., Leng, Z. T., Stapleton, P., and Weiss, N. S. The glutathione S-transferase μ polymorphism as a marker for susceptibility to lung carcinoma. Cancer Res, 53 (Suppl.): 2313-2318, 1993
51. Seidegard, J., Pero, R. W., Miller, D. G., and Beattie, E. J. A glutathione transferase in human leukocytes as a marker for the susceptibility to lung cancer Carcinogenesis (Lond.), 7: 751-753, 1986.
52. Brockmöller, J., Kerb, R., Drakoulis, N., Nitz, M., and Roots, I. Genotype and phenotype of glutathione S-transferase class μ isoenzymes μ and ψ in lung cancer patients and controls Cancer Res., 53: 1004-1011, 1993.
53. Nakachi, K., Imai, K., Hayashi, S., and Kawajiri, K. Polymorphisms of the CYP1A1 and glutathione S-transferase genes associated with susceptibility to lung cancer in relation to cigarette dose in a Japanese population. Cancer Res., 55: 2994-2999, 1993.
54. Bell, D. A., Stephens, E. A., Castranio, T., Umbach, D. M., Watson, M., Deakin, M., Elder, J., Hendrickse, C., Duncan, H., and Strange, R. C. Polyadenylation polymorphism in the acetyltransferase 1 gene (NAT1) increases risk of colorectal cancer. Cancer Res., 55: 3537-3542, 1995.