Genetic determinants of lung cancer short-term survival: The role of glutathione-related genes

Lung Cancer

Volumn 35, Issue 3, 2002, Pages 221-229

  Yang, Ping ^a   Yokomizo, Akira ^a   Tazelaar, Henry D ^a   Marks, Randolph S ^a   Lesnick, Timothy G ^a   Miller, Daniel L ^a   Sloan, Jeff A ^a   Edell, Eric S ^a   Meyer, Rebecca L ^a   Jett, James ^a   Liu, Wanguo ^a  

^a MAYO CLINIC   (United States)

Author keywords

Chemotherapeutic; Glutathoine; Metabolism

Indexed keywords

BIOLOGICAL MARKER; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; PLATINUM DERIVATIVE;

ARTICLE; CANCER DIAGNOSIS; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE LOCUS; GENOTYPE; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; PREDICTION; PRIORITY JOURNAL; REGRESSION ANALYSIS; SMOKING CESSATION; SURVIVAL RATE; TREATMENT PLANNING;

FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE TRANSFERASE; HUMANS; LUNG NEOPLASMS; MALE; NEOPLASM STAGING; POLYMORPHISM, GENETIC; PROGNOSIS; SMOKING; SURVIVAL RATE; TIME FACTORS;

EID: 0036181438     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-5002(01)00426-3     Document Type: Article

References (65)

1. Cancer of the lung
2. Revisions in the international system for staging lung cancer
3. Importance of glutathione and associated enzymes in drug response
4. The glutathione S-transferase supergene family: Regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance
5. Invited commentary: Potential contribution of the glutathione S-transferase supergene family to resistance to oxidative stress
6. Glutathione S-transferase isoenzymes and glutathione peroxidase activity in normal and tumour samples from human lung
7. Glutathione and related enzyme activity in human lung cancer cell lines
8. Mammalian glutathione S-transferase: Regulation of an enzyme system to achieve chemotherapeutic efficacy
9. Glutathione S transferase Pi is a powerful indicator in chemotherapy of human lung squamous-cell carcinoma
10. Immunohistochemical expression of glutathione S-transferase-Pi can predict chemotherapy response in patients with nonsmall cell lung carcinoma
11. Glutathione derivatives enhance Adriamycin cytotoxicity in a human lung adenocarcinoma cell line
12. Expression of mu class glutathione S-transferase correlates with event-free survival in childhood acute lymphoblastic leukemia
13. Relationship of glutathione and glutathione-S-transferase to cisplatin sensitivity in human head and neck squamous carcinoma cell lines
14. Cellular basis for differential sensitivity to cisplatin in human germ cell tumour and colon carcinoma cell lines
15. Factors influencing the sensitivity of two human bladder carcinoma cell lines to cis-diamminedichloroplatinum(II)
16. Decreased DNA interstrand cross-linking and cytotoxicity induced in human brain tumor cells by 1,3-bis(2-chloroethyl)-1-nitrosourea after in vitro reaction with glutathione
17. Sensitization of drug resistant human ovarian cancer cells to cyanomorpholino doxorubicin (MRA-CN) by modulation of glutathione metabolism
18. Mechanism of cross-resistance to cisplatin in a mitomycin C-resistant human bladder cancer cell line
19. Role of glutathione and dependent enzymes in anthracycline-resistant HL60/AR cells
20. Relationship between melanogenesis, glutathione levels and melphalan toxicity in human melanoma cells
21. Mitomycin C sensitivity in human bladder cancer cells: Possible role of glutathione and glutathione transferase in resistance
22. Determinants of drug response in a cisplatin-resistant human lung cancer cell line
23. Expression of glutathione S-transferase-pi in human ovarian cancer as an indicator of resistance to chemotherapy
24. Immunohistochemical expression of glutathione S-transferase pi (GST-pi) and chemotherapy response in malignant ovarian tumors
25. Expression of glutathione S-transferase-pi in operative specimens as marker of chemoresistance in patients with ovarian cancer
26. Glutathione concentration may be a useful predictor of response to second-line chemotherapy in patients with ovarian cancer
27. Biological markers as a predictor for response and prognosis of unresectable gastric cancer patients treated with 5-fluorouracil and cis-platinum
28. Prognostic significance of the expressions of metallothionein, glutathione-S-transferase-pi, and P-glycoprotein in curatively resected gastric cancer
29. Correlated expression of glutathione S-transferase-p and c-Jun or other oncogene products in human squamous cell carcinomas of the head and neck: Relevance to relapse after radiation therapy
30. A pilot study of pi-class glutathione S-transferase expression in breast cancer: Correlation with estrogen receptor expression and prognosis in node-negative breast cancer
31. Glutathione S-transferase pi in colorectal tumors is predictive for overall survival
32. P-glycoprotein and glutathione S-transferase pi in childhood acute lymphoblastic leukemia
33. Expression of glutathione transferase pi as a predictor for treatment results at different stages of acute nonlymphoblastic leukemia
34. Role of cellular glutathione and glutathione S-transferase in the expression of alkylating agent cytotoxicity in human breast cancer cells
35. Genetic heterogeneity of the human glutathione transferases: A complex of gene families
36. Nomenclature for human glutathione transferases
37. Molecular epidemiology of the human glutathione S-transferase genotypes GSTM1 and GSTT1 in cancer susceptibility
38. Pi-class glutathione S-transferase: Regulation and function
39. Polymorphism of the Pi class glutathione S-transferase in normal populations and cancer patients
40. Genetic mapping of GLCLC, the human gene encoding the catalytic subunit of gamma-glutamyl-cysteine synthetase, to chromosome band 6p12 and characterization of a polymorphic trinucleotide repeat within its 5′ untranslated region
41. Glutathione S-transferase M1 (GSTM1) deficiency and lung cancer risk
42. Polymorphisms in the glutathione S-transferase class mu and theta genes interact and increase susceptibility to lung cancer in minority populations (Texas, United States)
43. Combined effect of polymorphic GST genes on individual susceptibility to lung cancer
44. 1-antitrypsin deficiency allele carriers in lung cancer patients
45. Identification of genetic polymorphisms at the glutathione S-transferase Pi locus and association with susceptibility to bladder, testicular and prostate cancer
46. Hereditary difference in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion
47. Mutant fibrillin-1 monomers lacking EGF-like domains disrupt microfibril assembly and cause severe marfan syndrome
48. Denaturing high performance liquid chromatography (DHPLC) used in the detection of germline and somatic mutations
49. Mechanisms of resistance of human tumours to anticancer drugs of the platinum family: A review
50. Clinical studies of reversal of drug resistance based on glutathione
51. Increased cisplatin sensitivity of human fibroblasts from a subject with inherent glutathione deficiency
52. Prognostic significance of germ line polymorphisms of the CYP1A1 and glutathione S-transferase genes in patients with non-small cell lung cancer
53. Analysis of L-myc and GSTM1 genotypes in Chinese non-small cell lung carcinoma patients
54. Association of glutathione S-transferase GSTM1 and GSTT1 null genotypes with clinical outcome in epithelial ovarian cancer
55. p53 mutation spectrum in relation to GSTM1, CYP1A1 and CYP2E1 in surgically treated patients with non-small cell lung cancer
56. Single tube multiplex polymerase chain reaction genotype analysis of GSTM1, GSTT1 and GSTP1: Relation of genotypes to TP53 tumor status and clinico-pathological variables in breast cancer patients
57. Pharmacokinetics of the taxanes
58. Pharmacology of the taxanes
59. Assays of CYP2C8- and CYP3A4-mediated metabolism of taxol in vivo and in vitro
60. Microsatellite instability in human cancer: A prognostic marker for chemotherapy?
61. Drug resistance
62. Relevance of DNA repair to carcinogenesis and cancer therapy