메뉴 건너뛰기




Volumn 32, Issue 3, 2005, Pages 233-239

In vivo apoptosis detection with radioiodinated Annexin V in LoVo tumour-bearing mice following Tipifarnib (Zarnestra, R115777) farnesyltransferase inhibitor therapy

Author keywords

Annexin V; Apoptosis; Farnesyl transferase inhibitor; Oncology; Tipifarnib

Indexed keywords

BETA CYCLODEXTRIN; HYDROCHLORIC ACID; IODINE 123; LIPOCORTIN 5; LIPOCORTIN 5 I 123; PROTEIN FARNESYLTRANSFERASE INHIBITOR; TIPIFARNIB; UNCLASSIFIED DRUG;

EID: 16844377487     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2005.01.001     Document Type: Article
Times cited : (12)

References (31)
  • 1
    • 0035908493 scopus 로고    scopus 로고
    • Blocking oncogenic Ras signalling for cancer therapy
    • A.A. Adjei Blocking oncogenic Ras signalling for cancer therapy J. Natl. Cancer Inst. 93 2001 1062 1074
    • (2001) J. Natl. Cancer Inst. , vol.93 , pp. 1062-1074
    • Adjei, A.A.1
  • 2
    • 0034084453 scopus 로고    scopus 로고
    • The role of polypeptide growth factors in human carcinomas: New targets for a novel pharmacological approach
    • R.E. Favoni, and A. De Cupis The role of polypeptide growth factors in human carcinomas: New targets for a novel pharmacological approach Pharmacol. Rev. 52 2000 179 206
    • (2000) Pharmacol. Rev. , vol.52 , pp. 179-206
    • Favoni, R.E.1    De Cupis, A.2
  • 3
    • 0034730625 scopus 로고    scopus 로고
    • Farnesyltransferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with mictotubules
    • H.R. Ashar, L. James, K. Gray, D. Carr, S. Black, and L. Armstrong Farnesyltransferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with mictotubules J. Biol. Chem. 275 2000 30451 30457
    • (2000) J. Biol. Chem. , vol.275 , pp. 30451-30457
    • Ashar, H.R.1    James, L.2    Gray, K.3    Carr, D.4    Black, S.5    Armstrong, L.6
  • 4
    • 0141842714 scopus 로고    scopus 로고
    • Farnesyltransferase inhibitors: An overview of the results of preclinical and clinical investigations
    • T.B. Brunner, S.M. Hahn, A.K. Gupta, R.J. Muschel, W.G. McKenna, and E.J. Bernhard Farnesyltransferase inhibitors: An overview of the results of preclinical and clinical investigations Cancer Res. 63 2003 5656 5668
    • (2003) Cancer Res. , vol.63 , pp. 5656-5668
    • Brunner, T.B.1    Hahn, S.M.2    Gupta, A.K.3    Muschel, R.J.4    McKenna, W.G.5    Bernhard, E.J.6
  • 5
    • 0034674417 scopus 로고    scopus 로고
    • Both farnesylated and geranylgeranylated RhoB inhibit malignant transformation and suppress human tumor growth in nude mice
    • Z. Chen, J. Sun, A. Pradines, G. Favre, J. Adnane, and S.M. Sebti Both farnesylated and geranylgeranylated RhoB inhibit malignant transformation and suppress human tumor growth in nude mice J. Biol. Chem. 275 2000 17974 17978
    • (2000) J. Biol. Chem. , vol.275 , pp. 17974-17978
    • Chen, Z.1    Sun, J.2    Pradines, A.3    Favre, G.4    Adnane, J.5    Sebti, S.M.6
  • 6
    • 0034980637 scopus 로고    scopus 로고
    • Farnesyltransferase inhibitors. Potential role in the treatment of cancer
    • A.D. Cox Farnesyltransferase inhibitors. Potential role in the treatment of cancer Drugs 61 2001 726 732
    • (2001) Drugs , vol.61 , pp. 726-732
    • Cox, A.D.1
  • 7
    • 0033986790 scopus 로고    scopus 로고
    • The phosphoinositide 3-OH kinase/Akt2 pathway as a critical target for farnesyltranferase inhibitor-induced apoptosis
    • K. Jiang, D. Coppola, N.C. Crespo, S.V. Nicosia, A.D. Hamilton, and S.M. Sebti The phosphoinositide 3-OH kinase/Akt2 pathway as a critical target for farnesyltranferase inhibitor-induced apoptosis Mol. Cell Biol. 20 2000 139 148
    • (2000) Mol. Cell Biol. , vol.20 , pp. 139-148
    • Jiang, K.1    Coppola, D.2    Crespo, N.C.3    Nicosia, S.V.4    Hamilton, A.D.5    Sebti, S.M.6
  • 8
    • 0034050541 scopus 로고    scopus 로고
    • Farnesyltransferase inhibitors: Antineoplastic mechanism and clinical prospects
    • G.C. Prendergast Farnesyltransferase inhibitors: Antineoplastic mechanism and clinical prospects Curr. Opin. Cell Biol. 12 2000 166 173
    • (2000) Curr. Opin. Cell Biol. , vol.12 , pp. 166-173
    • Prendergast, G.C.1
  • 9
    • 0032169673 scopus 로고    scopus 로고
    • Farnesyltransferase inhibitors induce dramatic morphological changes of KNRK cells that are blocked by microtubule interfering agents
    • N. Suzuki, K. Keith Del Villar, and F. Tamanoi Farnesyltransferase inhibitors induce dramatic morphological changes of KNRK cells that are blocked by microtubule interfering agents Proc. Natl. Acad. Sci. U. S. A. 95 1998 10499 10504
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 10499-10504
    • Suzuki, N.1    Keith Del Villar, K.2    Tamanoi, F.3
  • 10
    • 0034777538 scopus 로고    scopus 로고
    • Protein farnesylation in mammalian cells: Effects of farnesyltransferase inhibitors on cancer cells
    • F. Tamanoi, C.-L. Gau, C. Jiang, H. Edamatsu, and J. Kato-Stankiewicz Protein farnesylation in mammalian cells: Effects of farnesyltransferase inhibitors on cancer cells Cell. Mol. Life Sci. 58 2001 1636 1649
    • (2001) Cell. Mol. Life Sci. , vol.58 , pp. 1636-1649
    • Tamanoi, F.1    Gau, C.-L.2    Jiang, C.3    Edamatsu, H.4    Kato-Stankiewicz, J.5
  • 11
    • 0031050738 scopus 로고    scopus 로고
    • Farnesyl transferase inhibitors induce apoptosis of Ras-transformed cells denied substratum attachment
    • P.Z. Lebowitz, D. Sakamuro, and G.C. Prendergast Farnesyl transferase inhibitors induce apoptosis of Ras-transformed cells denied substratum attachment Cancer Res. 57 1998 708 713
    • (1998) Cancer Res. , vol.57 , pp. 708-713
    • Lebowitz, P.Z.1    Sakamuro, D.2    Prendergast, G.C.3
  • 12
    • 0032417689 scopus 로고    scopus 로고
    • Farnesyltransferase inhibitors induce cytochrome c release and caspase 3 activation preferentially in transformed cells
    • N. Suzuki, J. Urano, and F. Tamanoi Farnesyltransferase inhibitors induce cytochrome c release and caspase 3 activation preferentially in transformed cells Proc. Natl. Acad. Sci. U. S. A. 95 1998 15356 15361
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 15356-15361
    • Suzuki, N.1    Urano, J.2    Tamanoi, F.3
  • 13
    • 4444314787 scopus 로고    scopus 로고
    • R115777 induces Ras-independent apoptosis of myeloma cells via multiple intrinsic pathways
    • D.M. Beaupre, E. Cepero, E.A. Obeng, L.H. Boise, and M.G. Lichtenheld R115777 induces Ras-independent apoptosis of myeloma cells via multiple intrinsic pathways Mol. Cancer Ther. 3 2004 179 186
    • (2004) Mol. Cancer Ther. , vol.3 , pp. 179-186
    • Beaupre, D.M.1    Cepero, E.2    Obeng, E.A.3    Boise, L.H.4    Lichtenheld, M.G.5
  • 14
    • 0035132538 scopus 로고    scopus 로고
    • Characterisation of the antitumor effects of the selective farnesyl protein transferase inhibitor R115777 in vivo and in vitro
    • D.W. End, G. Smets, A.V. Todd, T.L. Applegate, C.J. Fuery, and P. Angibaud Characterisation of the antitumor effects of the selective farnesyl protein transferase inhibitor R115777 in vivo and in vitro Cancer Res. 6 2001 131 137
    • (2001) Cancer Res. , vol.6 , pp. 131-137
    • End, D.W.1    Smets, G.2    Todd, A.V.3    Applegate, T.L.4    Fuery, C.J.5    Angibaud, P.6
  • 15
    • 0031983131 scopus 로고    scopus 로고
    • A farnesyltransferase inhibitor induces tumor regression in transgenic mice harboring multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis
    • L. Sepp-Lorenzino, and N. Rosen A farnesyltransferase inhibitor induces tumor regression in transgenic mice harboring multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis Mol. Cell. Biol. 18 1998 85 92
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 85-92
    • Sepp-Lorenzino, L.1    Rosen, N.2
  • 16
    • 0037081268 scopus 로고    scopus 로고
    • Farnesyltransferase inhibitors reverse Ras-mediated inhibition of Fas gene expression
    • B. Zhang, G.C. Prendergast, and R.G. Fenton Farnesyltransferase inhibitors reverse Ras-mediated inhibition of Fas gene expression Cancer Res. 62 2002 450 458
    • (2002) Cancer Res. , vol.62 , pp. 450-458
    • Zhang, B.1    Prendergast, G.C.2    Fenton, R.G.3
  • 17
    • 3042801329 scopus 로고    scopus 로고
    • Radioiodinated IGF-I as a possible biomarker for monitoring the effect of the farnesyl transferase inhibitor R115777
    • B. Cornelissen, A. Allaert, and G. Slegers Radioiodinated IGF-I as a possible biomarker for monitoring the effect of the farnesyl transferase inhibitor R115777 Eur. J. Nucl. Med. Mol. Imaging 30 2003 S191
    • (2003) Eur. J. Nucl. Med. Mol. Imaging , vol.30 , pp. 191
    • Cornelissen, B.1    Allaert, A.2    Slegers, G.3
  • 18
    • 16844364853 scopus 로고    scopus 로고
    • A rapid in vivo diagnostical assay to assess the effect of a farnesyl transferase inhibitor on LoVo cells using 123I-hEGF
    • B. Cornelissen, V. Kersemans, C. Vandewiele, R.A. Dierckx, and G. Slegers A rapid in vivo diagnostical assay to assess the effect of a farnesyl transferase inhibitor on LoVo cells using 123I-hEGF Cancer Biother. Radiopharm. 18 2003 283
    • (2003) Cancer Biother. Radiopharm. , vol.18 , pp. 283
    • Cornelissen, B.1    Kersemans, V.2    Vandewiele, C.3    Dierckx, R.A.4    Slegers, G.5
  • 19
    • 13944283610 scopus 로고    scopus 로고
    • 123I-EGF internalisation in tumour cells in vitro is inhibited by farnesyltransferase inhibitor therapy: Possible target for early therapy response prediction
    • B. Cornelissen, K. Remaut, V. Kersemans, R. Oltenfreiter, I. Burvenich, and G. Slegers 123I-EGF internalisation in tumour cells in vitro is inhibited by farnesyltransferase inhibitor therapy: Possible target for early therapy response prediction Eur. J. Nucl. Med. Mol. Imaging 31 2004 S391
    • (2004) Eur. J. Nucl. Med. Mol. Imaging , vol.31 , pp. 391
    • Cornelissen, B.1    Remaut, K.2    Kersemans, V.3    Oltenfreiter, R.4    Burvenich, I.5    Slegers, G.6
  • 23
  • 26
    • 0014861959 scopus 로고
    • Terminal lens cell differentiation
    • S.P. Modak, and F.J. Bollum Terminal lens cell differentiation Exp. Cell Res. 62 1970 421 432
    • (1970) Exp. Cell Res. , vol.62 , pp. 421-432
    • Modak, S.P.1    Bollum, F.J.2
  • 28
    • 0019302781 scopus 로고
    • Quantitative studies of cytological damage in mouse testis produced by exposure to heat
    • A.B. Cairnie, and K.E. Leach Quantitative studies of cytological damage in mouse testis produced by exposure to heat Can. J. Genet. Cytol. 22 1980 93 102
    • (1980) Can. J. Genet. Cytol. , vol.22 , pp. 93-102
    • Cairnie, A.B.1    Leach, K.E.2
  • 31
    • 16844368503 scopus 로고    scopus 로고
    • Quantitative tumour apoptosis imaging using 99mTc-HYNIC-Annexin V single photon emission computerized tomography
    • C. Van de Wiele, C. Lahorte, H. Vermeersch, D. Loose, K. Mervillie, and N.D. Steinmetz Quantitative tumour apoptosis imaging using 99mTc-HYNIC-Annexin V single photon emission computerized tomography Clin. J. Oncol. 21 2003 2483 2487
    • (2003) Clin. J. Oncol. , vol.21 , pp. 2483-2487
    • Van De Wiele, C.1    Lahorte, C.2    Vermeersch, H.3    Loose, D.4    Mervillie, K.5    Steinmetz, N.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.