Modulation of the expression of the transcription factor Max in rat retinal ganglion cells by a recombinant adeno-associated viral vector

Brazilian Journal of Medical and Biological Research

Volumn 38, Issue 3, 2005, Pages 375-379

  Petrs Silva, H ^a   Chiodo, V ^b   Chiarini, L B ^a   Hauswirth, W W ^b   Linden, R ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Gene therapy; Max expression; Neuroprotection; Retina; Transcription factor; Viral vector

Indexed keywords

MAX PROTEIN; PARVOVIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRAIN HEK293; CELL STRUCTURE; CONTROLLED STUDY; CORRELATION ANALYSIS; EXPLANT; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; NERVE FIBER DEGENERATION; NEUROPROTECTION; NEWBORN; NONHUMAN; PROTEIN DEPLETION; PROTEIN FUNCTION; RAT; RETINA GANGLION CELL; VITREOUS BODY;

ANIMALIA; MAMMALIA; PARVOVIRUS;

EID: 16844367457     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2005000300008     Document Type: Article

References (20)

1. Blackwood EM & Eisenman RN (1991). Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA binding complex with Myc. Science, 251: 1211-1217.
2. Amati B, Dalton S, Brooks MW, Littlewood TD, Evan GI & Land H (1992). Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max. Nature, 359: 423-426.
3. Evan GI, Wyllie AH, Gilbert CS, Littlewood TD & Land H (1992). Induction of apoptosis in fibroblasts by c-myc protein. Cell 69: 119-128.
4. Pelengaris S, Khan M & Evan G (2002). c-MYC: more than just a matter of life and death. Nature Reviews. Cancer, 10: 764-776.
5. Petrs-Silva H, de Freitas FG, Linden R & Chiarini LB (2004). Early nuclear exclusion of the transcription factor Max is associated with retinal ganglion cell death independent of caspase activity. Journal of Cellular Physiology, 198: 179-187.
6. Shen-Li H, O'Hagan RC, Hou Jr H, Horner 2nd JW, Lee HW & DePinho RA (2000). Essential role for Max in early embryonic growth and development. Genes and Development, 14: 17-22.
7. Shichiri M, Kato H, Doi M, Marumo F & Hirata Y (1999). Induction of Max by adrenomedullin and calcitonin gene-related peptide antagonizes endothelial apoptosis. Molecular Endocrinology, 13: 1353-1363.
8. Muzyczka N & Berns KI (2001). Parvoviridae: the viruses and their replication. In: Knipe DM & Howley PM (Editors), Fields Virology Vol. 2. Lippincott, Williams and Wilkins, Philadelphia, PA, USA, 2327-2359.
9. Muzyczka N (1992). Use of adeno-associated virus as a general transduction vector for mammalian cells. Current Topics in Microbiology and Immunology, 158: 97-129.
10. Samulski RJ, Sally M & Muzyczka N (1999). Adeno-associated viral vectors. In: Friedmann T (Editor), Development of Human Gene Therapy. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, USA, 131-172.
11. Chaum E & Hatton MP (2002). Gene therapy for genetic and acquired retinal diseases. Survey of Ophthalmology, 47: 449-469.
12. Liang FQ, Aleman TS, Dejneka NS, Dudus S, Fisher KJ, Maguire AM, Jacobson SG & Bennett J (2001). Long-term protection of retinal structure but not function using rAAV. CNTF in animal models of retinitis pigmentosa. Molecular Therapy, 4: 461-472.
13. Hansen KA, Sugino IK, Yagi F, Wang H, Tsukahara I, Gullapalli V, Bennett J & Zarbin MA (2003). Adeno-associated virus encoding green fluorescent protein as a label for retinal pigment epithelium. Investigative Ophthalmology and Visual Science, 44: 772-780.
14. Guy J, Qi X, Muzyczka N & Hauswirth WW (1999). Reporter expression persists 1 year after adeno-associated virus-mediated gene transfer to the optic nerve. Archives of Ophthalmology, 117: 929-937.
15. Zolotukhin S, Hauswirth WW & Muzyczka N (1996). A 'humanized' green fluorescent protein cDNA adapted for high-level expression in mammalian cells. Journal of Virology, 70: 4646-4654.
16. McCarty DM, Christensen M & Muzyczka N (1991). Sequences required for coordinate induction of adeno-associated virus p19 and p40 promoters by Rep protein. Journal of Virology, 65: 2936-2945.
17. Zolotukhin S, Potter M, Zolotukhin I et al. (2002). Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors. Methods, 28: 158-167.
18. Janson CG, McPhee SW, Leone P, Freese A & During MJ (2001). Viral-based gene transfer to the mammalian CNS for functional genomic studies. Trends in Neurosciences, 24: 706-712.
19. Simon PD, Vorwerk CK, Mansukani SS, Chen SJ, Wilson JM, Zurakowski D, Bennett J & Dreyer EB (1999). Bcl-2 gene therapy exacerbates excitotoxicity. Human Gene Therapy, 10: 1715-1720.
20. Nickells RW (1999). Apoptosis of retinal ganglion cells in glaucoma: an update of the molecular pathways involved in cell death. Survey of Ophthalmology, 43 (Suppl 1): S151-S161.