Presence of the Kv1.5 K+ channel in the sinoatrial node

Journal of Histochemistry and Cytochemistry

Volumn 48, Issue 6, 2000, Pages 769-780

  Dobrzynski, Halina ^a   Rothery, Stephen M ^b   Marples, David D R ^a   Coppen, Steven R ^b   Takagishi, Yoshiko ^c   Honjo, Haruo ^c   Tamkun, Michael M ^d   Henderson, Zaineb ^a   Kodama, Itsuo ^c   Severs, Nicholas J ^b   Boyett, Mark R ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b ROYAL BROMPTON HOSPITAL   (United Kingdom)

^c NAGOYA UNIVERSITY   (Japan)

^d Department of Ecosystem Science and Sustainability   (United States)

Author keywords

Desmosomes; Heart; Ion channels; Pacemaker

Indexed keywords

POTASSIUM CHANNEL;

ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; CONFOCAL MICROSCOPY; DESMOSOME; ELECTRON MICROSCOPY; FERRET; GAP JUNCTION; GUINEA PIG; IMMUNOFLUORESCENCE; IMMUNOGOLD STAINING; NONHUMAN; PRIORITY JOURNAL; SINUS NODE; WESTERN BLOTTING;

ANIMALIA; CAVIA PORCELLUS; MUSTELA PUTORIUS FURO; SUS SCROFA;

EID: 16744364440     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215540004800606     Document Type: Article

References (35)

1. Arnemann J, Sullivan KH, Magee AI, King IA, Buxton RS (1993) Stratification-related expression of isoforms of the desmosomal cadherins in human epidermis. J Cell Sci 104:741-750
2. + channels? Circ Res 77:361-369
3. Bleeker WK, Mackaay AJC, Masson-Pevet M, Bouman LN, Becker AE (1980) Functional and morphological organization of the rabbit sinus node. Circ Res 46:11-22
4. Boyett MR, Honjo H, Yamamoto M, Niwa R, Kodama I (1998) Regional differences in the effects of 4-aminopyridine within the sinoatrial node. Am J Physiol 44:H1158-1168
5. + current in isolated adult rat atrial myocytes. Am J Physiol 260:H1236-1247
6. + currents in rat atrial myocytes. J Gen Physiol 100:1041-1067
7. to) phenotypes and distribution of fast inactivating potassium channel alpha subunits in ferret left ventricular myocytes. J Gen Physiol 113:581-600
8. + channel mRNA in isolated ferret cardiac myocytes. Circ Res 78:1083-1089
9. Buxton RS, Magee AI (1992) Structure and interactions of desmosomal and other cadherins. Cell Biol 3:157-167
10. Carlemalm E, Garavito RM, Villiger W (1981) Resin development for electron microscopy and an analysis of embedding at low temperature. J Microsc 126:123-129
11. Cohen SA (1996) Immunocytochemical localization of rH1 sodium channel in adult rat heart atria and ventricle. Presence in terminal intercalated disks. Circulation 94:3083-3086
12. Coppen SR, Dupont E, Rothery S, Severs NJ (1998) Connexin45 expression is preferentially associated with the ventricular conduction system in mouse and rat heart. Circ Res 82:232-243
13. Coppen S, Kodama I, Boyett MR, Dobrzynski H, Takagishi Y, Honjo H, Yeh H-I, Severs N (1999) Connexin45, a major connexin of the rabbit sinoatrial node, is co-expressed with connexin43 in a restricted zone at the nodal-crista terminalis border. J Histochem Cytochem 47:907-918
14. + channel in ventricular muscle. A molecular correlate for the transient outward current. Circ Res 79:659-668
15. + channel current. Circ Res 73:210-216
16. + current in cultured adult human atrial myocytes. Circ Res 80:572-579
17. + current in rat ventricle. J Physiol 500:51-64
18. Honjo H, Lei M, Boyett MR, Kodama I (1999) Heterogeneity of 4-aminopyridine sensitive current in rabbit sinoatrial node cells. Am J Physiol 276:H1295-1304
19. Irisawa H, Brown HF, Giles W (1993) Cardiac pacemaking in the sino-atrial node. Physiol Rev 73:197-227
20. James TN, Sherf L, Fine G, Morales AR (1966) Comparative ultrastructure of the sinus node in man and dog. Circulation 34:139-163
21. Kijima Y, Saito A, Jetton TL, Magnuson MA, Fleischer S (1993) Different intracellular localization of inositol 1,4,5-triphosphate and ryanodine receptors in cardiomyocytcs. J Biol Chem 268: 3499-3506
22. + current in human atrial myocytes. Circ Res 78:903-915
23. + chanel protein in explanted cardiac tissue. J Clin Invest 96:282-292
24. Paulmichl M, Nasmith P, Hellmiss R, Reed K, Boyle WA, Nerbonne JM, Peralta EG, Clapham DE (1991) Cloning and expression of a rat cardiac delayed rectifier potassium channel. Proc Natl Acad Sci USA 88:7892-7895
25. Rubenstein DS, Fox LM, McNulty JA, Lipsius SL (1987) Electrophysiology and ultrastructure of Eustachian ridge from cat right atrium: a comparison with SA node. J Mol Cell Cardiol 19:965-976
26. Severs NJ (1989) Constituent cells of the heart and isolated cell models in cardiovascular research. In Piper HM, Isenberg G, eds. Isolated Adult Cardiomyocytes. Boca Raton, FL, CRS Press, 3-41
27. Severs NJ (1995) Cardiac muscle cell interactions: from microanatomy to the molecular make-up of the gap junction. Histol Histopathol 10:481-501
28. Severs NJ (1999) Cardiovascular disease. In Cardew G, ed. Gap Junction-Mediated Intercellular Signalling in Health and Disease. New York, John Wiley & Sons, 188-206
29. Slot JW, Geuze HJ (1984) Gold markers for single and double labeling of ultrathin cryosections. In Polak JM, Varndell IM, eds. Immunolabeling for Electron Microscopy. Amsterdam, Elsevier Science, 129-142
30. + channel cDNAs from human ventricle. FASEB J 5:331-337
31. ten Velde I, de Jonge B, Verheijck EE, van Kempen MJA, Analbers L, Gros D, Jongsma HJ (1995) Spatial distribution of connexin43, the major cardiac gap junction protein, visualizes the cellular network for impulse propagation from sinoatrial node to atrium. Cir Res 76:802-811
32. van Kempen MJA, ten Velde I, Wessels A, Oosthoek PW, Gros D, Jongsma HJ, Mooran AFM, Lamers WH (1995) Differential connexin distribution accomodates cardiac function in different species. Microsc Res Tech 31:420-436
33. + current similar to Kv1.5 cloned channel currents. Circ Res 73:1061-1076
34. Yeh H-I, Dupont E, Rothery S, Copper SR, Severs NJ (1998) Individual gap junction plaques contain multiple connexins in arterial endothelium. Circ Res 83:1248-1263
35. Yue L, Feng J, Li G-R, Nattel S (1996) Characterization of an ultrarapid delayed rectifier potassium channel in canine atrial repolarization. J Physiol 496:647-662