-
1
-
-
0028835253
-
A peptidomimetic inhibitor of farnesyl:Protein transferase blocks the anchorage-dependent and -Independent growth of human tumor cell lines
-
Sepp-Lorenzino L, Ma Z, Rands E, Kohl NE, Gibbs JB, Oliff A and Rosen N: A peptidomimetic inhibitor of farnesyl:protein transferase blocks the anchorage-dependent and -independent growth of human tumor cell lines. Cancer Res 55: 5302-5309, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 5302-5309
-
-
Sepp-Lorenzino, L.1
Ma, Z.2
Rands, E.3
Kohl, N.E.4
Gibbs, J.B.5
Oliff, A.6
Rosen, N.7
-
2
-
-
0032539559
-
Farnesyl transferase inhibitors cause enhanced mitotic sensitivity to taxol and epothilones
-
Moasser MM, Sepp-Lorenzino L, Kohl NE, Oliff A, Balog A, Su DS, Danishefsky SJ and Rosen N: Farnesyl transferase inhibitors cause enhanced mitotic sensitivity to taxol and epothilones. Proc Natl Acad Sci USA 95: 1369-1374, 1998.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 1369-1374
-
-
Moasser, M.M.1
Sepp-Lorenzino, L.2
Kohl, N.E.3
Oliff, A.4
Balog, A.5
Su, D.S.6
Danishefsky, S.J.7
Rosen, N.8
-
3
-
-
0019838759
-
Short chain fatty acids in the human colon
-
Cummings JH: Short chain fatty acids in the human colon. Gut 22: 763-779, 1981.
-
(1981)
Gut
, vol.22
, pp. 763-779
-
-
Cummings, J.H.1
-
4
-
-
0032446458
-
Differentiationinducing effect of retinoic acid, difluoromethylornithine, sodium butyrate and sodium suramin in human colon cancer cells
-
Reynolds S, Rajagopal S and Chakrabarty S: Differentiationinducing effect of retinoic acid, difluoromethylornithine, sodium butyrate and sodium suramin in human colon cancer cells. Cancer Lett 134: 53-60, 2001.
-
(2001)
Cancer Lett
, vol.134
, pp. 53-60
-
-
Reynolds, S.1
Rajagopal, S.2
Chakrabarty, S.3
-
5
-
-
0035841014
-
Tumor cell differentiation by butyrate and environmental stress
-
Witt O, Schulze S, Kanbach K, Roth C and Pekrun A: Tumor cell differentiation by butyrate and environmental stress. Cancer Lett 171: 173-182,2001.
-
(2001)
Cancer Lett
, vol.171
, pp. 173-182
-
-
Witt, O.1
Schulze, S.2
Kanbach, K.3
Roth, C.4
Pekrun, A.5
-
6
-
-
0031596491
-
Butyrate-induced Gl arrest results from p21-independent disruption of retinoblastoma protein-mediated signals
-
Vaziri C, Stice L and Faller DV: Butyrate-induced Gl arrest results from p21-independent disruption of retinoblastoma protein-mediated signals. Cell Growth Differ 9: 465-474, 1998.
-
(1998)
Cell Growth Differ
, vol.9
, pp. 465-474
-
-
Vaziri, C.1
Stice, L.2
Faller, D.V.3
-
7
-
-
0033558850
-
Sodium butyrate induces G2 arrest in the human breast cancer cells MDA-MB-231 and renders them competent for DNA rereplication
-
Lallemand F, Courilleau D, Buquet-Fagot C, Atfi A, Montagne MN and Mester J: Sodium butyrate induces G2 arrest in the human breast cancer cells MDA-MB-231 and renders them competent for DNA rereplication. Exp Cell Res 247: 432-440, 1999.
-
(1999)
Exp Cell Res
, vol.247
, pp. 432-440
-
-
Lallemand, F.1
Courilleau, D.2
Buquet-Fagot, C.3
Atfi, A.4
Montagne, M.N.5
Mester, J.6
-
8
-
-
0035835483
-
Effects of retinoic acid and sodium butyrate on gene expression, histone acetylation and inhibition of proliferation of melanoma cells
-
Demary K, Wong L and Spanjaard RA: Effects of retinoic acid and sodium butyrate on gene expression, histone acetylation and inhibition of proliferation of melanoma cells. Cancer Lett 163- 103-107,2001.
-
(2001)
Cancer Lett
, vol.163
, pp. 103-107
-
-
Demary, K.1
Wong, L.2
Spanjaard, R.A.3
-
9
-
-
0037114325
-
Apoptosis sensitivity is not correlated with sensitivity to proliferation inhibition by the histone deacetylase inhibitors butyrate and TSA
-
Galfi P, Neogrady Z and Csordas A: Apoptosis sensitivity is not correlated with sensitivity to proliferation inhibition by the histone deacetylase inhibitors butyrate and TSA. Cancer Lett 188: 141-152,2002.
-
(2002)
Cancer Lett
, vol.188
, pp. 141-152
-
-
Galfi, P.1
Neogrady, Z.2
Csordas, A.3
-
10
-
-
0030957625
-
Butyric acid and pivaloyloxymethyl butyrate, AN-9, a novel butyric acid derivative, induce apoptosis in HL-60 cells
-
Zimra Y, Wasserman L, Maron L, Shaklai M, Nudelman A and Rephaeli A: Butyric acid and pivaloyloxymethyl butyrate, AN-9, a novel butyric acid derivative, induce apoptosis in HL-60 cells. J Cancer Res Clin Oncol 123: 152-160, 1997.
-
(1997)
J Cancer Res Clin Oncol
, vol.123
, pp. 152-160
-
-
Zimra, Y.1
Wasserman, L.2
Maron, L.3
Shaklai, M.4
Nudelman, A.5
Rephaeli, A.6
-
11
-
-
0031954530
-
Phase I study of the orally administered butyrate prodrug, tributyrin, in patients with solid tumors
-
Conley B A, Egorin MJ, Tait N, Rosen DM, Saus ville EA, Dover G, Fram RJ and van Echo DA: Phase I study of the orally administered butyrate prodrug, tributyrin, in patients with solid tumors. Clin Cancer Res 4: 629-634, 1998.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 629-634
-
-
Conley, B.A.1
Egorin, M.J.2
Tait, N.3
Rosen, D.M.4
Saus Ville, E.A.5
Dover, G.6
Fram, R.J.7
Van Echo, D.A.8
-
12
-
-
0035992310
-
A phase I study of pivaloyloxymethyl butyrate, a prodrug of the differentiating agent butyric acid, in patients with advanced solid malignancies
-
Patnaik A, Rowinsky EK, Villalona MA, Hammond LA, Britten CD, Siu LL, Goetz A, Felton SA, Burton S, Valone FH and Eckhardt SG: A phase I study of pivaloyloxymethyl butyrate, a prodrug of the differentiating agent butyric acid, in patients with advanced solid malignancies. Clin Cancer Res 8: 2142-2148, 2002.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2142-2148
-
-
Patnaik, A.1
Rowinsky, E.K.2
Villalona, M.A.3
Hammond, L.A.4
Britten, C.D.5
Siu, L.L.6
Goetz, A.7
Felton, S.A.8
Burton, S.9
Valone, F.H.10
Eckhardt, S.G.11
-
13
-
-
0034930259
-
HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2
-
Wachtershauser A, Akoglu B and Stein J: HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2. Carcinogenesis 22: 1061-1067,2001.
-
(2001)
Carcinogenesis
, vol.22
, pp. 1061-1067
-
-
Wachtershauser, A.1
Akoglu, B.2
Stein, J.3
-
14
-
-
0037138434
-
Potentiating antitumor effects of a combination therapy with lovastatin and butyrate in the Lewis lung carcinoma model in mice
-
Giermasz A, Makowski M, Kozlowska E, Nowis D, Maj M, Jalili A, Feleszko W, Wojcik C, Dabrowska A, Jakobisiak M and Golab J: Potentiating antitumor effects of a combination therapy with lovastatin and butyrate in the Lewis lung carcinoma model in mice. Int J Cancer 97: 756-750, 2002.
-
(2002)
Int J Cancer
, vol.97
, pp. 756-1750
-
-
Giermasz, A.1
Makowski, M.2
Kozlowska, E.3
Nowis, D.4
Maj, M.5
Jalili, A.6
Feleszko, W.7
Wojcik, C.8
Dabrowska, A.9
Jakobisiak, M.10
Golab, J.11
-
15
-
-
0028216631
-
Branch-point reactions in the biosynthesis of cholesterol, dolichol, ubiquinone and prenylated proteins
-
Grunler J, Ericsson J and Dallner G: Branch-point reactions in the biosynthesis of cholesterol, dolichol, ubiquinone and prenylated proteins. Biochim Biophys Acta 1212: 259-277, 1994.
-
(1994)
Biochim Biophys Acta
, vol.1212
, pp. 259-277
-
-
Grunler, J.1
Ericsson, J.2
Dallner, G.3
-
16
-
-
0035976039
-
Human breast cancer MDA-MB-231 cells fail to express the neurofibromin protein, lack its type I mRNA isoform and show accumulation of P-MAPK and activated Ras
-
Ogata H, Sato H, Takatsuka J and De Luca LM: Human breast cancer MDA-MB-231 cells fail to express the neurofibromin protein, lack its type I mRNA isoform and show accumulation of P-MAPK and activated Ras. Cancer Lett 172: 159-164, 2001.
-
(2001)
Cancer Lett
, vol.172
, pp. 159-164
-
-
Ogata, H.1
Sato, H.2
Takatsuka, J.3
De Luca, L.M.4
-
17
-
-
0037038684
-
Farnesyltransferase inhibitor (L-744,832) restores TGF-beta type II receptor expression and enhances radiation sensitivity in K-ras mutant pancreatic cancer cell line MIA PaCa-2
-
Alcock RA, Dey S, Chendil D, Inayat MS, Mohiuddin M, Hartman G, Chatfield LK, Gallicchio VS and Ahmed MM: Farnesyltransferase inhibitor (L-744,832) restores TGF-beta type II receptor expression and enhances radiation sensitivity in K-ras mutant pancreatic cancer cell line MIA PaCa-2. Oncogene 21:7883-7990,2002.
-
(2002)
Oncogene
, vol.21
, pp. 7883-7990
-
-
Alcock, R.A.1
Dey, S.2
Chendil, D.3
Inayat, M.S.4
Mohiuddin, M.5
Hartman, G.6
Chatfield, L.K.7
Gallicchio, V.S.8
Ahmed, M.M.9
-
18
-
-
0019750732
-
Criteria for analyzing interactions between biologically active agents
-
Berenbaum MC: Criteria for analyzing interactions between biologically active agents. Adv Cancer Res 35: 269-335, 1981.
-
(1981)
Adv Cancer Res
, vol.35
, pp. 269-335
-
-
Berenbaum, M.C.1
-
19
-
-
0345772125
-
Antitumor effects of photodynamic therapy are potentiated by 2-mefhoxyestradiol. A superoxide dismutase inhibitor
-
Golab J, Nowis D, Skrzycki M, Czeczot H, Baranczyk-Kuzma A, Wilczynski GM, Makowski M, Mroz P, Kozar K, Kaminski R, Jalili A, Kopec M, Grzela T and Jakobisiak M: Antitumor effects of photodynamic therapy are potentiated by 2-mefhoxyestradiol. A superoxide dismutase inhibitor. J Biol Chem 278: 407-414, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 407-414
-
-
Golab, J.1
Nowis, D.2
Skrzycki, M.3
Czeczot, H.4
Baranczyk-Kuzma, A.5
Wilczynski, G.M.6
Makowski, M.7
Mroz, P.8
Kozar, K.9
Kaminski, R.10
Jalili, A.11
Kopec, M.12
Grzela, T.13
Jakobisiak, M.14
-
20
-
-
2542458153
-
Potential antitumor effects of statins
-
Review
-
Jakobisiak M and Golab J: Potential antitumor effects of statins (Review). Int J Oncol 23: 1055-1069, 2003.
-
(2003)
Int J Oncol
, vol.23
, pp. 1055-1069
-
-
Jakobisiak, M.1
Golab, J.2
-
21
-
-
0030568077
-
Inhibition of lung tumor cell growth in vitro and mouse lung tumor formation by lovastatin
-
Hawk MA, Cesen KT, Siglin JC, Stoner GD and Ruch RJ: Inhibition of lung tumor cell growth in vitro and mouse lung tumor formation by lovastatin. Cancer Lett 109: 217-222, 1996.
-
(1996)
Cancer Lett
, vol.109
, pp. 217-222
-
-
Hawk, M.A.1
Cesen, K.T.2
Siglin, J.C.3
Stoner, G.D.4
Ruch, R.J.5
-
22
-
-
0036828269
-
Discussion on 3- hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis
-
Kaminski R, Kozar K, Kopec M, Basak G, Skierski JS, Koronkiewicz M, Jakobisiak M and Golab J: Discussion on 3- hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors reduce human pancreatic cancer cell invasion and metastasis. Gastroenterology 123: 1747, 2002.
-
(2002)
Gastroenterology
, vol.123
, pp. 1747
-
-
Kaminski, R.1
Kozar, K.2
Kopec, M.3
Basak, G.4
Skierski, J.S.5
Koronkiewicz, M.6
Jakobisiak, M.7
Golab, J.8
-
23
-
-
0035908493
-
Blocking oncogenic Ras signaling for cancer therapy
-
Adjei AA: Blocking oncogenic Ras signaling for cancer therapy. J Natl Cancer Inst 93: 1062-1074, 2001.
-
(2001)
J Natl Cancer Inst
, vol.93
, pp. 1062-1074
-
-
Adjei, A.A.1
-
24
-
-
0029150669
-
Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice
-
Kohl NE, Omer CA, Conner MW, Anthony NJ, Davide JP, De Solms SJ, Giuliani EA, Gomez RP, Graham SL and Hamilton K: Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice. Nat Med 1:792-797, 1995.
-
(1995)
Nat Med
, vol.1
, pp. 792-797
-
-
Kohl, N.E.1
Omer, C.A.2
Conner, M.W.3
Anthony, N.J.4
Davide, J.P.5
De Solms, S.J.6
Giuliani, E.A.7
Gomez, R.P.8
Graham, S.L.9
Hamilton, K.10
-
25
-
-
0028318136
-
Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton
-
Prendergast GC, Davide JP, De Solms SJ, Giuliani EA, Graham SL, Gibbs JB, Oliff A and Kohl NE: Farnesyltransferase inhibition causes morphological reversion of ras-transformed cells by a complex mechanism that involves regulation of the actin cytoskeleton. Mol Cell Biol 14: 4193-4202, 1994.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 4193-4202
-
-
Prendergast, G.C.1
Davide, J.P.2
De Solms, S.J.3
Giuliani, E.A.4
Graham, S.L.5
Gibbs, J.B.6
Oliff, A.7
Kohl, N.E.8
-
26
-
-
0036134016
-
Potentiated antitumor effects of butyrate and actinomycin D in melanoma model in mice
-
Giermasz A, Makowski M, Nowis D, Jalili A, Maj M, Dabrowska A, Czajka A, Jakobisiak M and Golab J: Potentiated antitumor effects of butyrate and actinomycin D in melanoma model in mice. Oncol Rep 9: 199-203, 2002.
-
(2002)
Oncol Rep
, vol.9
, pp. 199-203
-
-
Giermasz, A.1
Makowski, M.2
Nowis, D.3
Jalili, A.4
Maj, M.5
Dabrowska, A.6
Czajka, A.7
Jakobisiak, M.8
Golab, J.9
-
27
-
-
0031439355
-
Promoting apoptosis: A novel activity associated with the cyclindependent kinase inhibitor p27
-
Katayose Y, Kim M, Rakkar AN, Li Z, Cowan KH and Seth P: Promoting apoptosis: a novel activity associated with the cyclindependent kinase inhibitor p27. Cancer Res 57: 5441-5445, 1997.
-
(1997)
Cancer Res
, vol.57
, pp. 5441-5445
-
-
Katayose, Y.1
Kim, M.2
Rakkar, A.N.3
Li, Z.4
Cowan, K.H.5
Seth, P.6
-
28
-
-
0030997297
-
Regulation of the cyclin-dependent kinase inhibitor p27 by degradation and phosphorylation
-
Alessandrini A, Chiaur DS and Pagano M: Regulation of the cyclin-dependent kinase inhibitor p27 by degradation and phosphorylation. Leukemia 11: 342-345, 1997.
-
(1997)
Leukemia
, vol.11
, pp. 342-345
-
-
Alessandrini, A.1
Chiaur, D.S.2
Pagano, M.3
-
29
-
-
0030863161
-
Induction of p27Kipl degradation and anchorage independence by Ras through the MAP kinase signaling pathway
-
Kawada M, Yamagoe S, Murakami Y, Suzuki K, Mizuno S and Uehara Y: Induction of p27Kipl degradation and anchorage independence by Ras through the MAP kinase signaling pathway. Oncogene 15: 629-637, 1997.
-
(1997)
Oncogene
, vol.15
, pp. 629-637
-
-
Kawada, M.1
Yamagoe, S.2
Murakami, Y.3
Suzuki, K.4
Mizuno, S.5
Uehara, Y.6
-
30
-
-
0032541671
-
Cell cycle targets of Ras/Raf signalling
-
Kerkhoff E and Rapp UR: Cell cycle targets of Ras/Raf signalling. Oncogene 17: 1457-1462, 1998.
-
(1998)
Oncogene
, vol.17
, pp. 1457-1462
-
-
Kerkhoff, E.1
Rapp, U.R.2
-
31
-
-
0033963601
-
Involvement of p21(Wafl/Cipl) and its cleavage by DEVD-caspase during apoptosis of colorectal cancer cells induced by butyrate
-
Chai F, Evdokiou A, Young GP and Zalewski PD: Involvement of p21(Wafl/Cipl) and its cleavage by DEVD-caspase during apoptosis of colorectal cancer cells induced by butyrate. Carcinogenesis 21: 7-14, 2000.0
-
(2000)
Carcinogenesis
, vol.21
, pp. 7-14
-
-
Chai, F.1
Evdokiou, A.2
Young, G.P.3
Zalewski, P.D.4
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