Histology and culture results among subjects with antibodies to CagA but no evidence of Helicobacter pylori infection with IgG ELISA

Scandinavian Journal of Gastroenterology

Volumn 40, Issue 3, 2005, Pages 312-318

  Ye, Weimin ^a   Held, Maria ^a   Enroth, Helena ^b   Kraaz, Wolfgang ^c   Engstrand, Lars ^a,d   Nyrén, Olof ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b Clinical Microbiology Laboratory   (Sweden)

^c UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^d SWEDISH INSTITUTE FOR INFECTIOUS DISEASE CONTROL   (Sweden)

Author keywords

Antibodies; Atrophy; CagA; Helicobacter pylori; Infection; Serology

Indexed keywords

ANTIBODY; CAGA ANTIBODY; CAGA PROTEIN; IMMUNOGLOBULIN G; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BACTERIUM CULTURE; CASE CONTROL STUDY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GASTROSCOPY; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPOTHESIS; IMMUNOBLOTTING; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SEROLOGY; STOMACH; STOMACH CANCER; SWEDEN;

ADENOCARCINOMA; AGED; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BIOPSY; DIAGNOSIS, DIFFERENTIAL; DNA, BACTERIAL; ENDOSCOPY, DIGESTIVE SYSTEM; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GASTRIC FUNDUS; GASTRIC MUCOSA; GASTRITIS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; IMMUNOGLOBULIN G; MALE; POLYMERASE CHAIN REACTION; PYLORIC ANTRUM; REPRODUCIBILITY OF RESULTS; RETROSPECTIVE STUDIES; STOMACH NEOPLASMS;

EID: 16444364294     PISSN: 00365521     EISSN: None     Source Type: Journal    
DOI: 10.1080/00365520510011542     Document Type: Article

References (21)

1. Dunn BE, Cohen H, Blaser MJ. Helicobacter pylori. Clin Microbiol Rev 1997;10:720-41.
2. Kuipers EJ. Helicobacter pylori and the risk and management of associated diseases: Gastritis, ulcer disease, atrophic gastritis and gastric cancer. Aliment Pharmacol Ther 1997; 1(11 Suppl):71-88.
3. Covacci A, Censini S, Bugnoli M, Petracca R, Burroni D, Macchia G, et al. Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer. Proc Natl Acad Sci USA 1993;90:5791-5.
4. Covacci A, Telford JL, Del Giudice G, Parsonnet J, Rappuoli R. Helicobacter pylori virulence and genetic geography. Science 1999;284:1328-33.
5. Sorberg M, Engstrand L, Strom M, Jonsson KA, Jorbeck H, Granstrom M. The diagnostic value of enzyme immunoassay and immunoblot in monitoring eradication of Helicobacter pylori. Scand J Infect Dis 1997;29:147-51.
6. Ekstrom AM, Held M, Hansson LE, Engstrand L, Nyren O. Helicobacter pylori in gastric cancer established by CagA immunoblot as a marker of past infection. Gastroenterology 2001;121:784-91.
7. Enroth H, Kraaz W, Engstrand L, Nyren O, Rohan T. Helicobacter pylori strain types and risk of gastric cancer: A case-control study. Cancer Epidemiol Biomarkers Prev 2000;9:981-5.
8. Enroth H, Kraaz W, Rohan T, Nyren O, Engstrand L. Does the method of Helicobacter pylori detection influence the association with gastric cancer risk? Scand J Gastroenterol 2002;37:884-90.
9. Tummuru MK, Cover TL, Blaser MJ. Cloning and expression of a high-molecular-mass major antigen of Helicobacter pylori: Evidence of linkage to cytotoxin production. Infect Immun 1993;61:1799-809.
10. Dixon MF, Genta RM, Yardley JH, Correa P. Classification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis, Houston 1994. Am J Surg Pathol 1994;20:1161-81.
11. Altman DG, Machin D, Bryant TN, Gardner MJ, editors. Statistics with confidence. Bristol: Br Med J 2000.
12. Xia HH, Talley NJ. Natural acquisition and spontaneous elimination of Helicobacter pylori infection: Clinical implications. Am J Gastroenterol 1997;92:1780-7.
13. Meijer BC, Thijs JC, Kleibeuker JH, van Zwet AA, Berrelkamp RJ. Evaluation of eight enzyme immunoassays for detection of immunoglobulin G against Helicobacter pylori. J Clin Microbiol 1997;35:292-4.
14. Cainzos M, Potel J, Puente JL. Anergy in patients with biliary lithiasis. Br J Surg 1989;76:169-72.
15. Perez-Perez GI, Peek RM, Legath AJ, Heine PR, Graff LB. The role of CagA status in gastric and extragastric complications of Helicobacter pylori. J Physiol Pharmacol 1999;50:833-45.
16. Nilsson T, Lapidus L, Lindstedt G, Nystrom E, Eggertsen R. Relations between Helicobacter pylori, thyroid disease and cardiovascular risk factors in a 56-65-year-old population. Scand J Prim Health Care 2000;18:111-2.
17. Regnstrom J, Jovinge S, Bavenholm P, Ericsson CG, De Faire U, Hamsten A, et al. Helicobacter pylori seropositivity is not associated with inflammatory parameters, lipid concentrations and degree of coronary artery disease. J Intern Med 1998;243:109-13.
18. Agreus L, Engstrand L, Svardsudd K, Nyren O, Tibblin G. Helicobacter pylori seropositivity among Swedish adults with and without abdominal symptoms. A population-based epidemiologic study. Scand J Gastroenterol 1995;30:752-7.
19. van Doom LJ, Figueiredo C, Sanna R, Plaisier A, Schneeberger P, de Boer W, et al. Clinical relevance of the cagA, vacA, and iceA status of Helicobacter pylori. Gastroenterology 1998;115:58-66.
20. Rudi J, Rudy A, Maiwald M, Kuck D, Sieg A, Stremmel W. Direct determination of Helicobacter pylori vacA genotypes and cagA gene in gastric biopsies and relationship to gastrointestinal diseases. Am J Gastroenterol 1999;94: 1525-31.
21. Alarcon T, Domingo D, Martinez MJ, Lopez-Brea M. CagA gene and vacA alleles in Spanish Helicobacter pylori clinical isolates from patients of different ages. FEMS Immunol Med Microbiol 1999;24:215-9.