A New Aliphatic Amino Prodrug System for the Delivery of Small Molecules and Proteins Utilizing Novel PEG Derivatives

Journal of Medicinal Chemistry

Volumn 47, Issue 3, 2004, Pages 726-734

  Greenwald, Richard B ^a   Zhao, Hong ^a   Yang, Karen ^a   Reddy, Prasanna ^a   Martinez, Anthony ^a  

^a Enzon Incorporated   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALIPHATIC AMINE; AMINE; BIS(2 HYDROXYETHYL)GLYCINAMIDE; ESTER DERIVATIVE; GLYCINAMIDE; MACROGOL; PEPTIDE; PRODRUG; PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CONTROLLED DRUG RELEASE; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG HALF LIFE; DRUG HYDROLYSIS; DRUG SOLUBILITY; DRUG SYNTHESIS; IN VIVO STUDY;

AMINES; ANIMALS; ESTERS; GLYCINE; HALF-LIFE; HYDROLYSIS; MURAMIDASE; POLYETHYLENE GLYCOLS; PRODRUGS; PROTEINS; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 1642581054     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm030369+     Document Type: Article

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