-
1
-
-
0025048023
-
Sialosyl-Tn. A novel mucin antigen associated with prognosis in colorectal cancer patients
-
Itzkowitz SH, Bloom EJ, Kokal WA, Modin G, Hakomori S and Kim YS: Sialosyl-Tn: a novel mucin antigen associated with prognosis in colorectal cancer patients. Cancer 66: 1960-1966, 1990. (Pubitemid 20385969)
-
(1990)
Cancer
, vol.66
, Issue.9
, pp. 1960-1966
-
-
Itzkowitz, S.H.1
Bloom, E.J.2
Kokal, W.A.3
Modin, G.4
Hakomori, S.-I.5
Kim, Y.S.6
-
2
-
-
0027250266
-
x antigen correlates with poor survival in patients with colorectal carcinoma: Clinicopathological and immunohistochemical study
-
x antigen correlates with poor survival in patients with colorectal carcinoma: clinicopathological and immunohistochemical study. Cancer Res 53: 3632-3637, 1993.
-
(1993)
Cancer Res
, vol.53
, pp. 3632-3637
-
-
Nakamori, S.1
Kameyama, M.2
Imaoka, S.3
Furukawa, H.4
Ishikawa, O.5
Sasaki, Y.6
Kabuto, T.7
Iwanaga, T.8
Matushita, Y.9
Irimura, T.10
-
4
-
-
0022559251
-
b, X and Y blood group antigens in human colonic tumors and normal tissue and in human tumor derived cell lines
-
b, X and Y blood group antigens in human colonic tumors and normal tissue and in human tumor derived cell lines. Cancer Res 46: 1553-1561, 1986.
-
(1986)
Cancer Res
, vol.46
, pp. 1553-1561
-
-
Sakamoto, J.1
Furukawa, K.2
Cordon-Cardo, C.3
Yin, B.W.T.4
Rettig, W.J.5
Oettgen, H.F.6
Old, L.J.7
Lloyd, K.O.8
-
5
-
-
0028981052
-
Detection of p21 ras mutations in colorectal adenomas and carcinomas by enzyme-linked immunosorbent assay
-
Schroy PC III, Brown Shimer S, Kim K, Johnson KA, Murnane MJ, Yang S, O'Brien MJ, Carney WP and Kupchik HZ: Detection of p21 ras mutations in colorectal adenomas and carcinomas by enzyme-linked immunosorbent assay. Cancer 76: 201-209, 1995.
-
(1995)
Cancer
, vol.76
, pp. 201-209
-
-
Schroy III, P.C.1
Brown Shimer, S.2
Kim, K.3
Johnson, K.A.4
Murnane, M.J.5
Yang, S.6
O'Brien, M.J.7
Carney, W.P.8
Kupchik, H.Z.9
-
6
-
-
0030017179
-
A detailed analysis of K-ras point mutations in relation to tumor progression and survival in colorectal cancer patients
-
DOI 10.1002/(SICI)1097-0215(19960621)69:3<241::AID
-
Span M, Moerkerk PT, De Goeij AF and Arends JW: A detailed analysis of K-ras point mutations in relation to tumor progression and survival in colorectal cancer patients. Int J Cancer 69: 241-245, 1996. (Pubitemid 26233305)
-
(1996)
International Journal of Cancer
, vol.69
, Issue.3
, pp. 241-245
-
-
Span, M.1
Moerkerk, P.T.M.2
De Goeij, A.F.P.M.3
Arends, J.W.4
-
7
-
-
0028879677
-
P53 point mutation and survival in colorectal cancer patients
-
Goh HS, Yao J and Smith DR: P53 point mutation and survival in colorectal cancer patients. Cancer Res 55: 5217-5221, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 5217-5221
-
-
Goh, H.S.1
Yao, J.2
Smith, D.R.3
-
8
-
-
0017716458
-
Thymidylate synthase: A target enzyme in cancer chemotherapy
-
Danenberg PV: Thymidylate synthase: a target enzyme in cancer chemotherapy. Biochim Biophys Acta 473: 73-92, 1977.
-
(1977)
Biochim Biophys Acta
, vol.473
, pp. 73-92
-
-
Danenberg, P.V.1
-
9
-
-
0344662418
-
A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumor sensitivity to fluorouracil
-
Beck A, Etienne MC, Chradame S, Fischel JL, Formento P, Rene N and Milano G: A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumor sensitivity to fluorouracil. Eur J Cancer 10: 1408-1411, 1994.
-
(1994)
Eur J Cancer
, vol.10
, pp. 1408-1411
-
-
Beck, A.1
Etienne, M.C.2
Chradame, S.3
Fischel, J.L.4
Formento, P.5
Rene, N.6
Milano, G.7
-
10
-
-
0026795489
-
Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and resistant human cancer cell lines
-
Johnston PG, Drake JC, Trepel J and Allegra CJ: Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and resistant human cancer cell lines. Cancer Res 52: 4306-4312, 1992.
-
(1992)
Cancer Res
, vol.52
, pp. 4306-4312
-
-
Johnston, P.G.1
Drake, J.C.2
Trepel, J.3
Allegra, C.J.4
-
11
-
-
0022344622
-
Thymidylate synthase overproduction and gene amplification in fluorodeoxyuridine-resistant human cells
-
Berger SH, Jenh CH, Johnston LF and Berger FG: Thymidylate synthase overproduction and gene amplification in fluorodeoxyuridine-resistant human cells. Mol Pharmacol 28: 461-467, 1985. (Pubitemid 16224251)
-
(1985)
Molecular Pharmacology
, vol.28
, Issue.5
, pp. 461-467
-
-
Berger, S.H.1
Jenh, C.H.2
Johnson, L.F.3
Berger, F.G.4
-
12
-
-
0026030052
-
Induction of thymidylate synthase associated with multidrug resistance in human breast and colon cancer cell lines
-
Chu E, Drake JC, Koeller DM, Zinn S, Jamis-Dow CA, Yeh GC and Allegra CJ: Induction of thymidylate synthase associated with multidrug resistance in human breast and colon cancer cell lines. Mol Pharmacol 39: 136-143, 1991.
-
(1991)
Mol Pharmacol
, vol.39
, pp. 136-143
-
-
Chu, E.1
Drake, J.C.2
Koeller, D.M.3
Zinn, S.4
Jamis-Dow, C.A.5
Yeh, G.C.6
Allegra, C.J.7
-
13
-
-
0023111335
-
Thymidylate synthase gene amplification in a colon tumor resistant to fluoropyrimidine chemotherapy
-
Clark JL, Berger SH, Mittelman A and Berger FG: Thymidylate synthase gene amplification in a colon tumor resistant to fluoropyrimidine chemotherapy. Cancer Treat Rep 71: 261-265, 1987. (Pubitemid 17051726)
-
(1987)
Cancer Treatment Reports
, vol.71
, Issue.3
, pp. 261-265
-
-
Clark, J.L.1
Berger, S.H.2
Mittelman, A.3
Berger, F.G.4
-
14
-
-
0028019880
-
Thymidylate synthase inhibition after administration of fluorouracil with or without leucovorin in colon cancer patients: Implications for treatment with fluorouracil
-
Peters GJ, van der Wilt CL, van Groeningen CJ, Smid K, Meijer S and Pinedo HM: Thymidylate synthase inhibition after administration of fluorouracil with and without leucovorin in colon cancer patients: implication for treatment with fluorouracil. J Clin Oncol 12: 2035-2042, 1994. (Pubitemid 24356018)
-
(1994)
Journal of Clinical Oncology
, vol.12
, Issue.10
, pp. 2035-2042
-
-
Peters, G.J.1
Van Der, W.C.L.2
Van Groeningen, C.J.3
Smid, K.4
Meijer, S.5
Pinedo, H.M.6
-
15
-
-
0028609523
-
Thymidylate synthase levels in tumor biopsies from patients with colorectal cancer
-
Mulder NH, Timmer-Bosscha H, Meersma GJ and Verschueren RC: Thymidylate synthase levels in tumor biopsies from patients with colorectal cancer. Anticancer Res 14B: 2677-2680, 1994.
-
(1994)
Anticancer Res
, vol.14 B
, pp. 2677-2680
-
-
Mulder, N.H.1
Timmer-Bosscha, H.2
Meersma, G.J.3
Verschueren, R.C.4
-
16
-
-
0029095796
-
Quantitation of intratumoral thymidylate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: Preliminary report from an ongoing trial
-
Leichman L, Lenz HJ, Leichman CG, Groshen S, Danenberg K, Baranda J, Spears CP, Boswell W, Silberman H, Ortega A, Stain S, Breart R and Danenberg P: Quantitation of intratumoral thymidylate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: preliminary report from an ongoing trial. Eur J Cancer 31: 1306-1310, 1995.
-
(1995)
Eur J Cancer
, vol.31
, pp. 1306-1310
-
-
Leichman, L.1
Lenz, H.J.2
Leichman, C.G.3
Groshen, S.4
Danenberg, K.5
Baranda, J.6
Spears, C.P.7
Boswell, W.8
Silberman, H.9
Ortega, A.10
Stain, S.11
Breart, R.12
Danenberg, P.13
-
17
-
-
0026335113
-
The production and characterization of monoclonal antibodies that localize human thymidylate synthase in the cytoplasm of human cells and tissue
-
Johnston PG, Liang CM, Henry S, Chabner BA and Allegra CJ: The production and characterization of monoclonal antibodies that localize human thymidylate synthase in the cytoplasm of human cells and tissue. Cancer Res 51: 6668-6676, 1991.
-
(1991)
Cancer Res
, vol.51
, pp. 6668-6676
-
-
Johnston, P.G.1
Liang, C.M.2
Henry, S.3
Chabner, B.A.4
Allegra, C.J.5
-
18
-
-
0028151449
-
The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer
-
Johnston PG, Fisher ER, Rockette HE, Fisher B, Wolmark N, Drake JC, Chabner BA and Allegra CJ: The role of thymidylate synthase expression in prognosis and outcome to adjuvant chemotherapy in patients with rectal cancer. J Clin Oncol 12: 2640-2647, 1994. (Pubitemid 24379651)
-
(1994)
Journal of Clinical Oncology
, vol.12
, Issue.12
, pp. 2640-2647
-
-
Johnston, P.G.1
Fisher, E.R.2
Rockette, H.E.3
Fisher, B.4
Wolmark, N.5
Drake, J.C.6
Chabner, B.A.7
Allegra, C.J.8
-
19
-
-
15444349773
-
p53 and thymidylate synthase expression in untreated stage II colon cancer: Associations with recurrence, survival, and site
-
Lenz HJ, Kathleen DD, Leichman CG, Florentine B, Johnston PG, Groshen S, Zhou L, Xiong YP, Deneberg PV and Leichman LP: p53 and thymidylate synthase expression in untreated stage II colon cancer: associations with recurrence, survival, and site. Clin Cancer Res 4: 1227-1234, 1998. (Pubitemid 28213334)
-
(1998)
Clinical Cancer Research
, vol.4
, Issue.5
, pp. 1227-1234
-
-
Lenz, H.-J.1
Danenberg, K.D.2
Leichman, C.G.3
Florentine, B.4
Johnston, P.G.5
Groshen, S.6
Zhou, L.7
Xiong, Y.P.8
Danenberg, P.V.9
Leichman, L.P.10
-
20
-
-
0031941249
-
A new prognostic factor for colorectal carcinoma, thymidylate synthase, and its therapeutic significance
-
DOI 10.1002/(SICI)1097-0142(19980101)82:1<70::AID
-
Yamachika T, Nakanishi H, Inada K, Tsukamoto T, Kato T, Fukushima M, Inoue M and Tatematsu M: A new prognostic factor for colorectal carcinoma, thymidylate synthase and its therapeutic significance. Cancer 82: 70-77, 1998. (Pubitemid 28070481)
-
(1998)
Cancer
, vol.82
, Issue.1
, pp. 70-77
-
-
Yamachika, T.1
Nakanishi, H.2
Inada, K.-I.3
Tsukamoto, T.4
Kato, T.5
Fukushima, M.6
Inoue, M.7
Tatematsu, M.8
-
21
-
-
0028940399
-
Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors
-
Johnston PG, Lenz HJ, Leichman CG, Danenberg KD, Allegra CJ, Danenberg PV and Leichman L: Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors. Cancer Res 55: 1407-1412, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 1407-1412
-
-
Johnston, P.G.1
Lenz, H.J.2
Leichman, C.G.3
Danenberg, K.D.4
Allegra, C.J.5
Danenberg, P.V.6
Leichman, L.7
-
22
-
-
0029095796
-
Quantitation of intratumoral thymidylate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: Preliminary report from an ongoing trial
-
Leichman L, Lenz HJ, Leichman CG, Groshen S, Danenberg KD, Baranda J, Spears CP, Boswell W, Silberman H, Ortega A, Stain S, Beart R and Danenberg P: Quantitation of intratumoral thymidylate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers: preliminary report from an ongoing trial. Eur J Cancer 718: 1306-1310, 1995.
-
(1995)
Eur J Cancer
, vol.718
, pp. 1306-1310
-
-
Leichman, L.1
Lenz, H.J.2
Leichman, C.G.3
Groshen, S.4
Danenberg, K.D.5
Baranda, J.6
Spears, C.P.7
Boswell, W.8
Silberman, H.9
Ortega, A.10
Stain, S.11
Beart, R.12
Danenberg, P.13
-
23
-
-
0026335113
-
Production and characterization of monoclonal antibodies that localize human thymidylate synthase in the cytoplasm of human cells and tissue
-
Johnston PG, Liang CM, Henry S, Chabner BA and Allegra CJ: Production and characterization of monoclonal antibodies that localize human thymidylate synthase in the cytoplasm of human cells and tissue. Cancer Res 51: 6668-6676, 1991.
-
(1991)
Cancer Res
, vol.51
, pp. 6668-6676
-
-
Johnston, P.G.1
Liang, C.M.2
Henry, S.3
Chabner, B.A.4
Allegra, C.J.5
-
24
-
-
0026795489
-
Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines
-
Johnston PG, Drake JC, Trepel J and Allegra CJ: Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines. Cancer Res 52: 4306-4312, 1992.
-
(1992)
Cancer Res
, vol.52
, pp. 4306-4312
-
-
Johnston, P.G.1
Drake, J.C.2
Trepel, J.3
Allegra, C.J.4
-
25
-
-
0030743239
-
Preparation of the antibodies against recombinant human thymidylate synthase for the detection of its intratumoral levels and the application to sensitivity-study of 5-fluorouracil
-
Okabe H, Tsujimoto H and Fukushima M: Preparation of the antibodies against recombinant human thymidylate synthase for the detection of its intratumoral levels and the application to sensitivity-study of 5-fluorouracil. Oncol Rep 4: 685-690, 1997. (Pubitemid 27286971)
-
(1997)
Oncology Reports
, vol.4
, Issue.4
, pp. 685-690
-
-
Okabe, H.1
Tsujimoto, H.2
Fukushima, M.3
-
26
-
-
0032526245
-
Epitope mapping of a series of human thymidylate synthase monoclonal antibodies
-
Behan KA, Johnston PG and Allegra GJ: Epitope mapping of a series of human thymidylate synthase monoclonal antibodies. Cancer Res 58: 2606-2611, 1998. (Pubitemid 28275433)
-
(1998)
Cancer Research
, vol.58
, Issue.12
, pp. 2606-2611
-
-
Behan, K.A.1
Johnston, P.G.2
Allegra, C.J.3
-
27
-
-
0034132258
-
Epitope analysis and utility of monoclonal antibodies to native and recombinant human thymidylate synthase
-
Okabe H, Koizumi K, Tujimoto H and Fukushima M: Epitope analysis and utility of monoclonal antibodies to native and recombinant human thymidylate synthase. Int J Mol Med 5: 133-138, 2000.
-
(2000)
Int J Mol Med
, vol.5
, pp. 133-138
-
-
Okabe, H.1
Koizumi, K.2
Tujimoto, H.3
Fukushima, M.4
-
28
-
-
0028151449
-
The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer
-
Johnston PG, Fisher ER, Rockette HE, Fisher B, Wolmaek N, Drake JC, Chanbner BA and Allegra CJ: The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer. J Clin Oncol 12: 2640-2647, 1994. (Pubitemid 24379651)
-
(1994)
Journal of Clinical Oncology
, vol.12
, Issue.12
, pp. 2640-2647
-
-
Johnston, P.G.1
Fisher, E.R.2
Rockette, H.E.3
Fisher, B.4
Wolmark, N.5
Drake, J.C.6
Chabner, B.A.7
Allegra, C.J.8
-
29
-
-
84951601829
-
A generalized Wilcoxon test for comparing arbitrarily single-censored samples
-
Gehan EA: A generalized Wilcoxon test for comparing arbitrarily single-censored samples. Biometrika 52: 203-223, 1965.
-
(1965)
Biometrika
, vol.52
, pp. 203-223
-
-
Gehan, E.A.1
-
30
-
-
0000336139
-
Regression models and life-tables
-
Cox DR: Regression models and life-tables. JR Stat Soc Ser B 34: 187-220, 1972.
-
(1972)
JR Stat Soc Ser B
, vol.34
, pp. 187-220
-
-
Cox, D.R.1
-
31
-
-
33845382806
-
Non-parametric estimation from incomplete observations
-
Kaplan EL and Meier P: Non-parametric estimation from incomplete observations. J Am Stat Assoc 53: 457-481, 1958.
-
(1958)
J Am Stat Assoc
, vol.53
, pp. 457-481
-
-
Kaplan, E.L.1
Meier, P.2
-
32
-
-
0032997572
-
Immunohistochemical quantitation of thymidylate syntase expression in colorectal cancer metastases predicts for clinical outcome to fluorouracil-based chemotherapy
-
Carlo A, Domizia D, Stefania C, Giovanna A, Gianni T, Chiara B, Rita L, Frank M and Alberto S: Immunohistochemical quantitation of thymidylate syntase expression in colorectal cancer metastases predicts for clinical outcome to fluorouracil-based chemotherapy. J Clin Oncol 17: 1760-1770, 1999.
-
(1999)
J Clin Oncol
, vol.17
, pp. 1760-1770
-
-
Carlo, A.1
Domizia, D.2
Stefania, C.3
Giovanna, A.4
Gianni, T.5
Chiara, B.6
Rita, L.7
Frank, M.8
Alberto, S.9
-
33
-
-
6544276581
-
Thymidylate synthase protein expression in advanced colon cancer: Correlation with the site of metastasis and the clinical response to leucovorin-modulated bolus 5-fluorouracil
-
Cascinu S, Aschele C, Bami S, Debemardis D, Baldo C, Tunesi G, Catalano V, Staccioli MP, Brenna A, Muretto P and Catalano G: Thymidylate synthase protein expression in advanced colon cancer: correlation with the site of metastasis and the clinical response to leucovolin-modulated bolus 5-fluorouracil. Clin Cancer Res 5: 1996-1999, 1999. (Pubitemid 29399249)
-
(1999)
Clinical Cancer Research
, vol.5
, Issue.8
, pp. 1996-1999
-
-
Cascinu, S.1
Aschele, C.2
Barni, S.3
Debernardis, D.4
Baldo, C.5
Tunesi, G.6
Catalano, V.7
Staccioli, M.P.8
Brenna, A.9
Muretto, P.10
Catalano, G.11
-
34
-
-
0031947357
-
Higher levels of thymidylate synthase gene expression are observed in pulmonary as compared with hepatic metastases of colorectal adenocarcinoma
-
Gorlic R, Metzger R, Dannenberg KD, Salonga D, Miles JS, Longo GSA, Fu J, Banerjee D, Klimstra D, Jhanwar S, Dannenberg P, Kemeny N and Bertino JR: Higher levels of thymidylate syntase gene expression are observed in pulmonary as compared with hepatic metastases of colorectal adenocarcinoma. J Clin Oncol 16: 1465-1469, 1998. (Pubitemid 28175767)
-
(1998)
Journal of Clinical Oncology
, vol.16
, Issue.4
, pp. 1465-1469
-
-
Gorlick, R.1
Metzger, R.2
Danenberg, K.D.3
Salonga, D.4
Miles, J.S.5
Longo, G.S.A.6
Fu, J.7
Banerjee, D.8
Klimstra, D.9
Jhanwar, S.10
Danenberg, P.V.11
Kemeny, N.12
Bertino, J.R.13
-
35
-
-
0027409845
-
Dependence of the thymidylate synthase inhibition rate on the interval after the last administration of tegafur in sigmoid colon cancer patients
-
DOI 10.1002/jso.2930520212
-
Nozue M, Koike N, Kawamoto T, Toko K, Shindou T, Orii K, Kondou T, Mun Y, Nithou M, Todoroki T and Fukao K: Dependence of the thymidylate synthase inhibition rate on the interval after the last administration of tegafur in sigmoid colon cancer patients. J Surg Oncol 52: 115-118, 1993. (Pubitemid 23061961)
-
(1993)
Journal of Surgical Oncology
, vol.52
, Issue.2
, pp. 115-118
-
-
Nozue, M.1
Koike, N.2
Kawamoto, T.3
Toko, K.4
Sindou, T.5
Orii, K.6
Kondou, T.7
Mun, Y.8
Nithou, M.9
Todoroki, T.10
Fukao, K.11
-
36
-
-
0033564283
-
Ethnic variation in the thymidylate synthase enhancer region polymorphism among Caucasian and Asian populations
-
DOI 10.1006/geno.1999.5833
-
Marsh S, Collie-Duguid ESR, Li T, Liu X and McLeod HL: Ethnic variation in the thymidylate synthase enhancer region polymorphism among Caucasian and Asian populations Genomics 58: 310-312, 1999. (Pubitemid 29300314)
-
(1999)
Genomics
, vol.58
, Issue.3
, pp. 310-312
-
-
Marsh, S.1
Collie-Duguid, E.S.R.2
Li, T.3
Liu, X.4
McLeod, H.L.5
-
37
-
-
0033427561
-
Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinal cancers
-
Kawakami K, Omura K, Kanehira E and Watanabe Y: Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinal cancers. Anticancer Res 19: 3249-3252, 1999. (Pubitemid 30042617)
-
(1999)
Anticancer Research
, vol.19
, Issue.4 B
, pp. 3249-3252
-
-
Kawakami, K.1
Omura, K.2
Kanehira, E.3
Watanabe, Y.4
|