Successful treatment of drug-resistant cutaneous leishmaniasis in humans by use of imiquimod, an immunomodulator

Clinical Infectious Diseases

Volumn 33, Issue 11, 2001, Pages 1847-1851

  Arevalo, Iracema ^a,b   Ward, Brian ^b   Miller, Richard ^c   Meng, Tze Chiang ^c   Najar, Enrique ^d   Alvarez, Eugenia ^d   Matlashewski, Greg ^a   Alejandro, Llanos Cuentas ^d  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^c 3M COMPANY   (United States)

^d INSTITUTO DE MEDICINA TROPICAL ALEXANDER VON HUMBOLDT   (Peru)

Author keywords

[No Author keywords available]

Indexed keywords

IMIQUIMOD; MEGLUMINE ANTIMONATE; STIBOGLUCONATE SODIUM;

ARTICLE; CELL KILLING; DRUG EFFECT; ENDEMIC DISEASE; HUMAN; IMMUNE RESPONSE; IMMUNOMODULATION; LEISHMANIA; MACROPHAGE ACTIVATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; SKIN LEISHMANIASIS; TREATMENT FAILURE;

ADJUVANTS, IMMUNOLOGIC; ADOLESCENT; ADULT; AMINOQUINOLINES; ANTIPROTOZOAL AGENTS; CHILD; CHILD, PRESCHOOL; DRUG RESISTANCE; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; INFANT; LEISHMANIASIS, CUTANEOUS; MALE; MEGLUMINE; MIDDLE AGED; ORGANOMETALLIC COMPOUNDS; TREATMENT OUTCOME;

EID: 0035577828     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/324161     Document Type: Article

References (11)

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6. Post-therapy suppression of genital herpes simplex virus (HSV) recurrences and enhancement of HSV-specific T-cell memory by imiquimod in guinea pigs
7. Self-administered topical 5% imiquimod cream for external anogenital warts
8. Cytokine induction by the immunomodulators imiquimod and S-27609
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10. Identification of genes induced by a macrophage activator, S-28463, using gene expression array analysis
11. Roles of endogenous gamma interferon and macrophage microbicidal mechanisms in host response to chemotherapy in experimental visceral leishmaniasis