Analogues of LNA (Locked Nucleic Acid): Synthesis of the 2′-thio-LNA ribothymidine and 5-methylcytidine phosphoramidites

Synthesis

Volumn , Issue 4, 2004, Pages 578-582

  Pedersen, Daniel Sejer ^a,b   Koch, Troels ^a  

^a Santaris Pharma AS   (Denmark)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Antisense agents; Bicyclic compounds; Bioorganic chemistry; Hydrogenations; Nucleosides

Indexed keywords

REACTION KINETICS; SYNTHESIS (CHEMICAL);

DEBENZYLATION; LOCKED NUCLEIC ACID (LNA);

NUCLEIC ACIDS;

AMINE; BENZYL DERIVATIVE; BICYCLO COMPOUND; CARBOHYDRATE; CYTIDINE DERIVATIVE; HYDROXYL GROUP; NUCLEIC ACID; OXETANE DERIVATIVE; PHOSPHORAMIDIC ACID DERIVATIVE; THYMIDINE DERIVATIVE;

ARTICLE; CHEMICAL STRUCTURE; CONFORMATION; DEBENZYLATION; NUCLEIC ACID SYNTHESIS; QUANTUM YIELD; REACTION ANALYSIS; RING OPENING;

EID: 1642376004     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-815959     Document Type: Article

References (25)

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