Autoproteolytic activation of human aspartylglucosaminidase

Biochemical Journal

Volumn 378, Issue 2, 2004, Pages 363-371

  Saarela, Jani ^a   Oinonen, Carita ^b   Jalanko, Anu ^a   Rouvinen, Juha ^b   Peltonen, Leena ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Activation mechanism; Aspartylglucosaminidase; Aspartylglucosaminuria; Autocatalytic activation; Ntn hydrolase; Site directed mutagenesis

Indexed keywords

CHEMICAL BONDS; CONFORMATIONS; DISEASES; MUTAGENESIS; POLYPEPTIDES; STEREOCHEMISTRY;

ACTIVE SITES; AUTOCATALYSIS;

ENZYMES;

AMIDASE; HYDROLASE; N4 (BETA N ACETYLGLUCOSAMINYL)ASPARAGINASE; WATER;

AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME STRUCTURE; EUKARYOTE; HUMAN; MOLECULAR DYNAMICS; MOLECULE; MUTATION; NERVE DEGENERATION; PRIORITY JOURNAL; PROKARYOTE; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION;

AMINO ACIDS; ANIMALS; ASPARTYLGLUCOSYLAMINASE; CATALYSIS; CERCOPITHECUS AETHIOPS; COS CELLS; ENZYME ACTIVATION; HUMANS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; THREONINE;

EUKARYOTA; PROKARYOTA;

EID: 1642368967     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20031496     Document Type: Article

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