Crystal structure of HEL4, a soluble, refoldable human VH single domain with a germ-line scaffold

Journal of Molecular Biology

Volumn 337, Issue 4, 2004, Pages 893-903

  Jespers, Laurent ^a,b   Schon, Oliver ^a,b   James, Leo C ^a   Veprintsev, Dmitri ^a   Winter, Greg ^a  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b Domantis   (United Kingdom)

Author keywords

Antibody; CDR, complementarity determining regions; Crystal structure; dAb, domain antibody; Folding; HEL, hen egg lysozyme; Human VH; Kd , dissociation constant; Mr , molecular mass; Single domain

Indexed keywords

FIBRIN; GLYCINE; MONOMER;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DENATURATION; GERM LINE; HUMAN; HYDROPHOBICITY; IMMUNOTHERAPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN ISOLATION; X RAY CRYSTALLOGRAPHY;

CAMELIDAE; LAMA (CAMEL);

EID: 1642364974     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.02.013     Document Type: Article

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