Optimal Design Features of Camelized Human Single-domain Antibody Libraries

Journal of Biological Chemistry

Volumn 276, Issue 27, 2001, Pages 24774-24780

  Tanha, Jamshid ^a   Xu, Ping ^a   Chen, Zhigang ^a   Ni, Feng ^a   Kaplan, Howard ^b   Narang, Saran A ^a   MacKenzie, C Roger ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^b Viventia Biotech Inc   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; ANTIGENS; MASS SPECTROMETRY; SURFACE PLASMON RESONANCE;

OPTIMAL DESIGN;

BIOCHEMISTRY;

MONOCLONAL ANTIBODY; ANTIBODY; DISULFIDE; IMMUNOGLOBULIN HEAVY CHAIN; PEPTIDE FRAGMENT; PEPTIDE LIBRARY;

AMINO ACID SEQUENCE; ARTICLE; CAMELIZED HUMAN SINGLE DOMAIN ANTIBODY LIBRARY; CAMELIZED VH SEQUENCE; CARBOXY TERMINAL SEQUENCE; COMPLEMENTARITY DETERMINING REGION; COMPLEMENTARITY DETERMINING REGION 1; COMPLEMENTARITY DETERMINING REGION 3; DISULFIDE BOND; DNA LIBRARY; HUMAN VH LIBRARY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DOMAIN; PROTON NUCLEAR MAGNETIC RESONANCE; RANDOMIZATION; SEQUENCE ANALYSIS; SURFACE PLASMON RESONANCE; CHEMISTRY; GENETICS; HUMAN; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE;

AMINO ACID SEQUENCE; ANTIBODIES; ANTIBODIES, MONOCLONAL; BASE SEQUENCE; DISULFIDES; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN VARIABLE REGION; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PEPTIDE LIBRARY;

EID: 0035816720     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100770200     Document Type: Article

References (40)

1. Hamers-Casterman, C., Atarhouch, T., Muyldermans, S., Robinson, G., Hamers, C., Songa, Baiyana B., Bendahman, N., and Hamers, R. (1993) Nature 363, 446-448
2. Sheriff, S., and Constantine, K. L. (1996) Nat. Struct. Biol. 3, 733-736
3. Desmyter, A., Transue, T. R., Ghahroudi, M. A., Thi, M. H., Poortmans, F., Hamers, R., Muyldermans, S., and Wyns, L. (1996) Nat. Struct. Biol. 3, 803-811
4. Spinelli, S., Frenken, L., Bourgeois, D., de Ron, L., Bos, W., Verrips, T., Anguille, C., Cambillau, C., and Tegoni, M. (1996) Nat. Struct. Biol. 3, 752-757
5. Davies, J., and Riechmann, L. (1994) FEBS Lett. 339, 285-290
6. Decanniere, K., Desmyter, A., Lauwereys, M., Ghahroudi, M. A., Muyldermans, S., and Wyns, L. (1999) Structure 7, 361-370
7. Nguyen, V. K., Hamers, R., Wyns, L., and Muyldermans, S. (2000) EMBO J. 19, 921-930
8. Muyldermans, S., Atarhouch, T., Saldanha, J., Barbosa, J. A., and Hamers, R. (1994) Protein Eng. 7, 1129-1135
9. Lauwereys, M., Arbabi, G. M., Desmyter, A., Kinne, J., Holzer, W., De Genst, E., Wyns, L., and Muyldermans, S. (1998) EMBO J. 17, 3512-3520
10. Vu, K. B., Ghahroudi, M. A., Wyns, L., and Muyldermans, S. (1997) Mol. Immunol. 34, 1121-1131
11. Davies, J., and Riechmann, L. (1996) Protein Eng 9, 531-537
12. Ward, E. S., Gussow, D., Griffiths, A. D., Jones, P. T., and Winter, G. (1989) Nature 341, 544-546
13. Davies, J., and Riechmann, L. (1995) Bio/Technology 13, 475-479
14. Arbabi, G. M., Desmyter, A., Wyns, L., Hamers, R., and Muyldermans, S. (1997) FEBS Lett. 414, 521-526
15. Reiter, Y., Schuck, P., Boyd, L. F., and Plaksin, D. (1999) J. Mol. Biol. 290, 685-698
16. Constantine, K. L., Goldfarb, V., Wittekind, M., Anthony, J., Ng, S. C., and Mueller, L. (1992) Biochemistry 31, 5033-5043
17. Constantine, K. L., Goldfarb, V., Wittekind, M., Friedrichs, M. S., Anthony, J., Ng, S. C., and Mueller, L. (1993) J. Biomol. NMR 3, 41-54
18. Dan, M. D., Earley, E. M., Griffin, M. C., Maiti, P. K., Prashar, A. K., Yuan, X. Y., Friesen, A. D., and Kaplan, H. A. (1995) J. Neurosurg. 82, 475-480
19. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd Ed., Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
20. Harrison, J. L., Williams, S. C., Winter, G., and Nissim, A. (1996) Methods Enzymol. 267, 83-109
21. MacKenzie, R., and To, R. (1998) J. Immunol. Methods 220, 39-49
22. Deng, S. J., MacKenzie, C. R., Sadowska, J., Michniewicz, J., Young, N. M., Bundle, D. R., and Narang, S. A. (1994) J. Biol. Chem. 269, 9533-9538
23. Anand, N. N., Mandal, S., MacKenzie, C. R., Sadowska, J., Sigurskjold, B., Young, N. M., Bundle, D. R., and Narang, S. A. (1991) J. Biol. Chem. 266, 21874-21879
24. Anand, N. N., Dubuc, G., Phipps, J., MacKenzie, C. R., Sadowska, J., Young, N. M., Bundle, D. R., and Narang, S. A. (1991) Gene (Amst.) 100, 39-44
25. MacKenzie, C. R., Sharma, V., Brummell, D., Bilous, D., Dubuc, G., Sadowska, J., Young, N. M., Bundle, D. R., and Narang, S. A. (1994) Bio/Technology 12, 390-395
26. Deng, S. J., MacKenzie, C. R., Hirama, T., Brousseau, R., Lowary, T. L., Young, N. M., Bundle, D. R., and Narang, S. A. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 4992-4996
27. Jönsson, U., Fågerstam, L., Ivarsson, B., Johnsson, B., Karlsson, R., Lundh, K., Löfås, S., Persson, B., Roos, H., Rönnberg, I., Sjölander, S., Sternberg, E., Ståhlberg, R., Urbaniczky, C., Östlin, H., and Malmqvist, M. (1991) BioTechniques 11, 620-627
28. Bodenhausen, G., and Ruben, D. J. (1980) Chem. Phys. Lett. 69, 185-188
29. Piotto, M., Saudek, V., and Sklenar, V. (1992) J. Biomol. NMR 2, 661-665
30. Sklenar, V., Piotto, M., Leppik, R., and Saudek, V. (1993) J. Magn. Reson. Sect. A 102, 241-245
31. Slatter, M., Schleucher, J., and Griesinger, C. (1999) Progr. NMR Spectrosc. 34, 93-158
32. Delaglio, F., Grzesiek, S., Vuister, G. W., Zhu, G., Pfeifer, J., and Bax, A. (1995) J. Biomol. NMR 6, 277-293
33. Johnson, B. A., and Blevins, R. A. (1994) J. Chem. Phys. 29, 1012-1014
34. Wishart, D. S., Bigam, C. G., Yao, J., Abildgaard, F., Dyson, H. J., Oldfield, E., Markley, J. L., and Sykes, B. D. (1995) J. Biomol. NMR 6, 135-140
35. Knappik, A., and Plückthun, A. (1994) BioTechniques 17, 754-761
36. Miceli, R. M., Degraaf, M. E., and Fischer, H. D. (1994) J. Immunol. Methods 167, 279-287
37. Kabat, E. A., Wu, T. T., Perry, H. M., Gottesman, K. S., and Foeller, C. (1991) Sequences of Proteins of Immunological Interest, United States Department of Health and Human Services, United States Public Health Service, Bethesda, MD
38. Riechmann, L., and Davies, J. (1995) J. Biomol. NMR 6, 141-152
39. Riechmann, L. (1996) J. Mol. Biol. 259, 957-969
40. Voordijk, S., Hansson, T., Hilvert, D., and van Gunsteren, W. F. (2000) J. Mol. Biol. 300, 963-973