메뉴 건너뛰기




Volumn 309, Issue 1, 2004, Pages 388-397

The N Terminus of the Human α1D-Adrenergic Receptor Prevents Cell Surface Expression

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1A ADRENERGIC RECEPTOR NT D; ALPHA 1B ADRENERGIC RECEPTOR NT D; ALPHA 1D ADRENERGIC RECEPTOR; ALPHA 1D ADRENERGIC RECEPTOR NT A; ALPHA 1D ADRENERGIC RECEPTOR NT B; CHIMERIC PROTEIN; GREEN FLUORESCENT PROTEIN; INOSITOL PHOSPHATE; NORADRENALIN; RADIOLIGAND; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

EID: 1642346628     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.060509     Document Type: Article
Times cited : (64)

References (41)
  • 2
    • 0034677632 scopus 로고    scopus 로고
    • The molecular architecture of odor and pheromone sensing in mammals
    • Buck LB (2000) The molecular architecture of odor and pheromone sensing in mammals. Cell 100:611-618.
    • (2000) Cell , vol.100 , pp. 611-618
    • Buck, L.B.1
  • 3
    • 0036236878 scopus 로고    scopus 로고
    • Differences in the cellular localization and agonist-mediated internalization properties of the alpha(1)-adrenoceptor subtypes
    • Chalothorn D, McCune DF, Edelmann SE, Garcia-Cazarin ML, Tsujimoto G, and Piascik MT (2002) Differences in the cellular localization and agonist-mediated internalization properties of the alpha(1)-adrenoceptor subtypes. Mol Pharmacol 61:1008-1016.
    • (2002) Mol Pharmacol , vol.61 , pp. 1008-1016
    • Chalothorn, D.1    McCune, D.F.2    Edelmann, S.E.3    Garcia-Cazarin, M.L.4    Tsujimoto, G.5    Piascik, M.T.6
  • 6
    • 0029584895 scopus 로고
    • Regulation of vascular smooth muscle growth by alpha1-adrenoreceptor subtypes in vitro and in situ
    • Chen L, Xin X, Eckhart AD, Yang N, and Faber JE (1995) Regulation of vascular smooth muscle growth by alpha1-adrenoreceptor subtypes in vitro and in situ. J Biol Chem 270:30980-30988.
    • (1995) J Biol Chem , vol.270 , pp. 30980-30988
    • Chen, L.1    Xin, X.2    Eckhart, A.D.3    Yang, N.4    Faber, J.E.5
  • 7
    • 0030908655 scopus 로고    scopus 로고
    • Subtype-specific intracellular trafficking of alpha2-adrenergic receptors
    • Daunt DA, Hurt C, Hein L, Kallio J, Feng F, and Kobilka BK (1997) Subtype-specific intracellular trafficking of alpha2-adrenergic receptors. Mol Pharmacol 51:711-720.
    • (1997) Mol Pharmacol , vol.51 , pp. 711-720
    • Daunt, D.A.1    Hurt, C.2    Hein, L.3    Kallio, J.4    Feng, F.5    Kobilka, B.K.6
  • 8
    • 0034255332 scopus 로고    scopus 로고
    • Localization of G-protein-coupled receptors in health and disease
    • Edwards SW, Tan CM, and Limbird LE (2000) Localization of G-protein-coupled receptors in health and disease. Trends Pharmacol Sci 21:304-308.
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 304-308
    • Edwards, S.W.1    Tan, C.M.2    Limbird, L.E.3
  • 9
    • 0028989919 scopus 로고
    • Cloning of the human alpha 1d-adrenergic receptor and inducible expression of three human subtypes in SK-N-MC cells
    • Esbenshade TA, Hirasawa A, Tsujimoto G, Tanaka T, Yano J, Minneman KP, and Murphy TJ (1995) Cloning of the human alpha 1d-adrenergic receptor and inducible expression of three human subtypes in SK-N-MC cells. Mol Pharmacol 47:977-985.
    • (1995) Mol Pharmacol , vol.47 , pp. 977-985
    • Esbenshade, T.A.1    Hirasawa, A.2    Tsujimoto, G.3    Tanaka, T.4    Yano, J.5    Minneman, K.P.6    Murphy, T.J.7
  • 10
    • 0029874397 scopus 로고    scopus 로고
    • Alpha 1-adrenergic receptor subtypes. Molecular structure, function and signaling
    • Graham RM, Perez DM, Hwa J, and Piascik MT (1996) alpha 1-adrenergic receptor subtypes. Molecular structure, function and signaling. Circ Res 78:737-749.
    • (1996) Circ Res , vol.78 , pp. 737-749
    • Graham, R.M.1    Perez, D.M.2    Hwa, J.3    Piascik, M.T.4
  • 11
    • 0035824582 scopus 로고    scopus 로고
    • Mutational and computational analysis of the alpha(1b)-adrenergic receptor. Involvement of basic and hydrophobic residues in receptor activation and G protein coupling
    • Greasley PJ, Fanelli F, Scheer A, Abuin L, Nenniger-Tosato M, DeBenedetti PG, and Cotecchia S (2001) Mutational and computational analysis of the alpha(1b)-adrenergic receptor. Involvement of basic and hydrophobic residues in receptor activation and G protein coupling. J Biol Chem 276:46485-46494.
    • (2001) J Biol Chem , vol.276 , pp. 46485-46494
    • Greasley, P.J.1    Fanelli, F.2    Scheer, A.3    Abuin, L.4    Nenniger-Tosato, M.5    DeBenedetti, P.G.6    Cotecchia, S.7
  • 12
    • 0026564303 scopus 로고
    • Enhancement of membrane insertion and function in a type IIIb membrane protein following introduction of a cleavable signal peptide
    • Guan XM, Kobilka TS, and Kobilka BK (1992) Enhancement of membrane insertion and function in a type IIIb membrane protein following introduction of a cleavable signal peptide. J Biol Chem 267:21995-21998.
    • (1992) J Biol Chem , vol.267 , pp. 21995-21998
    • Guan, X.M.1    Kobilka, T.S.2    Kobilka, B.K.3
  • 13
    • 0030864213 scopus 로고    scopus 로고
    • Subtype-specific differences in subcellular localization of alpha1-adrenoceptors: Chlorethylclonidine preferentially alkylates the accessible cell surface alpha1-adrenoceptors irrespective of the subtype
    • Hirasawa A, Sugawara T, Awaji T, Tsumaya K, Ito H, and Tsujimoto G (1997) Subtype-specific differences in subcellular localization of alpha1-adrenoceptors: chlorethylclonidine preferentially alkylates the accessible cell surface alpha1-adrenoceptors irrespective of the subtype. Mol Pharmacol 52:764-770.
    • (1997) Mol Pharmacol , vol.52 , pp. 764-770
    • Hirasawa, A.1    Sugawara, T.2    Awaji, T.3    Tsumaya, K.4    Ito, H.5    Tsujimoto, G.6
  • 14
    • 0030609135 scopus 로고    scopus 로고
    • Characterization of alpha1-adrenoceptor subtypes mediating contractions to phenylephrine in rat thoracic aorta, mesenteric artery and pulmonary artery
    • Hussain MB and Marshall I (1997) Characterization of alpha1-adrenoceptor subtypes mediating contractions to phenylephrine in rat thoracic aorta, mesenteric artery and pulmonary artery. Br J Pharmacol 122:849-858.
    • (1997) Br J Pharmacol , vol.122 , pp. 849-858
    • Hussain, M.B.1    Marshall, I.2
  • 15
    • 0034696925 scopus 로고    scopus 로고
    • Alpha(1)-adrenoceptor subtypes mediating contractions of the rat mesenteric artery
    • Hussain MB and Marshall I (2000) Alpha(1)-adrenoceptor subtypes mediating contractions of the rat mesenteric artery. Eur J Pharmacol 395:69-76.
    • (2000) Eur J Pharmacol , vol.395 , pp. 69-76
    • Hussain, M.B.1    Marshall, I.2
  • 16
    • 0037013244 scopus 로고    scopus 로고
    • The signal peptide of the G protein-coupled human endothelin B receptor is necessary for translocation of the N-terminal tail across the endoplasmic reticulum membrane
    • Kochl R, Alken M, Rutz C, Krause G, Oksche A, Rosenthal W, and Schulein R (2002) The signal peptide of the G protein-coupled human endothelin B receptor is necessary for translocation of the N-terminal tail across the endoplasmic reticulum membrane. J Biol Chem 277:16131-16138.
    • (2002) J Biol Chem , vol.277 , pp. 16131-16138
    • Kochl, R.1    Alken, M.2    Rutz, C.3    Krause, G.4    Oksche, A.5    Rosenthal, W.6    Schulein, R.7
  • 17
    • 0032417641 scopus 로고    scopus 로고
    • Identification of ligands for olfactory receptors by functional expression of a receptor library
    • Krautwurst D, Yau KW, and Reed RR (1998) Identification of ligands for olfactory receptors by functional expression of a receptor library. Cell 95:917-926.
    • (1998) Cell , vol.95 , pp. 917-926
    • Krautwurst, D.1    Yau, K.W.2    Reed, R.R.3
  • 18
    • 0033913768 scopus 로고    scopus 로고
    • Quantitative imaging in live human cells reveals intracellular alpha(1)-adrenoceptor ligand-binding sites
    • Mackenzie JF, Daly CJ, Pediani JD, and McGrath JC (2000) Quantitative imaging in live human cells reveals intracellular alpha(1)-adrenoceptor ligand-binding sites. J Pharmacol Exp Ther 294:434-443.
    • (2000) J Pharmacol Exp Ther , vol.294 , pp. 434-443
    • Mackenzie, J.F.1    Daly, C.J.2    Pediani, J.D.3    McGrath, J.C.4
  • 19
    • 0034034073 scopus 로고    scopus 로고
    • Regulation of the cellular localization and signaling properties of the alpha(1B)- and alpha(1D)-adrenoceptors by agonists and inverse agonists
    • McCune DF, Edelmann SE, Olges JR, Post GR, Waldrop BA, Waugh DJ, Perez DM, and Piascik MT (2000) Regulation of the cellular localization and signaling properties of the alpha(1B)- and alpha(1D)-adrenoceptors by agonists and inverse agonists. Mol Pharmacol 57:659-666.
    • (2000) Mol Pharmacol , vol.57 , pp. 659-666
    • McCune, D.F.1    Edelmann, S.E.2    Olges, J.R.3    Post, G.R.4    Waldrop, B.A.5    Waugh, D.J.6    Perez, D.M.7    Piascik, M.T.8
  • 20
    • 0027332131 scopus 로고
    • Coupling of expressed alpha 1B- and alpha 1D-adrenergic receptor to multiple signaling pathways is both G protein and cell type specific
    • Perez DM, DeYoung MB, and Graham RM (1993) Coupling of expressed alpha 1B- and alpha 1D-adrenergic receptor to multiple signaling pathways is both G protein and cell type specific. Mol Pharmacol 44:784-795.
    • (1993) Mol Pharmacol , vol.44 , pp. 784-795
    • Perez, D.M.1    DeYoung, M.B.2    Graham, R.M.3
  • 22
    • 0034742707 scopus 로고    scopus 로고
    • Alpha1-adrenergic receptors: New insights and directions
    • Piascik MT and Perez DM (2001) Alpha1-adrenergic receptors: new insights and directions. J Pharmacol Exp Ther 298:403-410.
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 403-410
    • Piascik, M.T.1    Perez, D.M.2
  • 23
    • 0037088693 scopus 로고    scopus 로고
    • Acute agonist-mediated desensitization of the human alpha 1a-adrenergic receptor is primarily independent of carboxyl terminus regulation: Implications for regulation of alpha 1aAR splice variants
    • Price RR, Morris DP, Biswas G, Smith MP, and Schwinn DA (2002) Acute agonist-mediated desensitization of the human alpha 1a-adrenergic receptor is primarily independent of carboxyl terminus regulation: implications for regulation of alpha 1aAR splice variants. J Biol Chem 277:9570-9579.
    • (2002) J Biol Chem , vol.277 , pp. 9570-9579
    • Price, R.R.1    Morris, D.P.2    Biswas, G.3    Smith, M.P.4    Schwinn, D.A.5
  • 24
    • 0037458592 scopus 로고    scopus 로고
    • N-Terminal truncation of human alpha(1D)-adrenoceptors increases expression of binding sites but not protein
    • Pupo AS, Uberti MA, and Minneman KP (2003) N-Terminal truncation of human alpha(1D)-adrenoceptors increases expression of binding sites but not protein. Eur J Pharmacol 462:1-8.
    • (2003) Eur J Pharmacol , vol.462 , pp. 1-8
    • Pupo, A.S.1    Uberti, M.A.2    Minneman, K.P.3
  • 27
    • 0029829504 scopus 로고    scopus 로고
    • Coupling efficiencies of human alpha 1-adrenergic receptor subtypes: Titration of receptor density and responsiveness with inducible and repressible expression vectors
    • Theroux TL, Esbenshade TA, Peavy RD, and Minneman KP (1996) Coupling efficiencies of human alpha 1-adrenergic receptor subtypes: titration of receptor density and responsiveness with inducible and repressible expression vectors. Mol Pharmacol 50:1376-1387.
    • (1996) Mol Pharmacol , vol.50 , pp. 1376-1387
    • Theroux, T.L.1    Esbenshade, T.A.2    Peavy, R.D.3    Minneman, K.P.4
  • 28
    • 0007598536 scopus 로고    scopus 로고
    • Radioligand binding assays for G-protein coupled receptor internalization
    • (Benovic JL ed), John Wiley & Sons, Inc., New York
    • Toews M (2000) Radioligand binding assays for G-protein coupled receptor internalization, in Regulation of G-Protein Coupled Receptor Function and Expression (Benovic JL ed) pp 199-230, John Wiley & Sons, Inc., New York.
    • (2000) Regulation of G-Protein Coupled Receptor Function and Expression , pp. 199-230
    • Toews, M.1
  • 29
    • 0037379190 scopus 로고    scopus 로고
    • Alpha 1-adrenergic receptor responses in alpha 1AB-AR knockout mouse hearts suggest the presence of alpha 1D-AR
    • Turnbull L, McCloskey DT, O'Connell TD, Simpson PC, and Baker AJ (2003) Alpha 1-adrenergic receptor responses in alpha 1AB-AR knockout mouse hearts suggest the presence of alpha 1D-AR. Am J Physiol 284:H1104-H1109.
    • (2003) Am J Physiol , vol.284
    • Turnbull, L.1    McCloskey, D.T.2    O'Connell, T.D.3    Simpson, P.C.4    Baker, A.J.5
  • 30
    • 0036082288 scopus 로고    scopus 로고
    • Biochemistry and pharmacology of epitope-tagged alpha(1)-adrenergic receptor subtypes
    • Vicentic A, Robeva A, Rogge G, Uberti M, and Minneman KP (2002) Biochemistry and pharmacology of epitope-tagged alpha(1)-adrenergic receptor subtypes. J Pharmacol Exp Ther 302:58-65.
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 58-65
    • Vicentic, A.1    Robeva, A.2    Rogge, G.3    Uberti, M.4    Minneman, K.P.5
  • 31
    • 0035861729 scopus 로고    scopus 로고
    • Rab5-dependent trafficking of the m4 muscarinic acetylcholine receptor to the plasma membrane, early endosomes and multivesicular bodies
    • Volpicelli LA, Lah JJ, and Levey AI (2001) Rab5-dependent trafficking of the m4 muscarinic acetylcholine receptor to the plasma membrane, early endosomes and multivesicular bodies. J Biol Chem 276:47590-47598.
    • (2001) J Biol Chem , vol.276 , pp. 47590-47598
    • Volpicelli, L.A.1    Lah, J.J.2    Levey, A.I.3
  • 32
    • 0027396746 scopus 로고
    • Subtype-specific differences in the intracellular sorting of G protein-coupled receptors
    • von Zastrow M, Link R, Daunt D, Barsh G, and Kobilka B (1993) Subtype-specific differences in the intracellular sorting of G protein-coupled receptors. J Biol Chem 268:763-766.
    • (1993) J Biol Chem , vol.268 , pp. 763-766
    • Von Zastrow, M.1    Link, R.2    Daunt, D.3    Barsh, G.4    Kobilka, B.5
  • 33
    • 0034071808 scopus 로고    scopus 로고
    • Identification of distinct carboxyl-terminal domains mediating internalization and down-regulation of the hamster alpha(1B)-adrenergic receptor
    • Wang J, Wang L, Zheng J, Anderson JL, and Toews ML (2000) Identification of distinct carboxyl-terminal domains mediating internalization and down-regulation of the hamster alpha(1B)-adrenergic receptor. Mol Pharmacol 57:687-694.
    • (2000) Mol Pharmacol , vol.57 , pp. 687-694
    • Wang, J.1    Wang, L.2    Zheng, J.3    Anderson, J.L.4    Toews, M.L.5
  • 34
    • 0030611423 scopus 로고    scopus 로고
    • A mutation in the hamster alpha1B-adrenergic receptor that differentiates two steps in the pathway of receptor internalization
    • Wang J, Zheng J, Anderson JL, and Toews ML (1997) A mutation in the hamster alpha1B-adrenergic receptor that differentiates two steps in the pathway of receptor internalization. Mol Pharmacol 52:306-313.
    • (1997) Mol Pharmacol , vol.52 , pp. 306-313
    • Wang, J.1    Zheng, J.2    Anderson, J.L.3    Toews, M.L.4
  • 35
    • 0025472052 scopus 로고
    • Comparison of alpha 1-adrenergic receptor-stimulated inositol phosphate formation in primary neuronal and glial cultures
    • Wilson KM, Gilchrist S, and Minneman KP (1990) Comparison of alpha 1-adrenergic receptor-stimulated inositol phosphate formation in primary neuronal and glial cultures. J Neurochem 55:691-697.
    • (1990) J Neurochem , vol.55 , pp. 691-697
    • Wilson, K.M.1    Gilchrist, S.2    Minneman, K.P.3
  • 36
    • 0029670035 scopus 로고    scopus 로고
    • The three alpha 2-adrenergic receptor subtypes achieve basolateral localization in Madin-Darby canine kidney H cells via different targeting mechanisms
    • Wozniak M and Limbird LE (1996) The three alpha 2-adrenergic receptor subtypes achieve basolateral localization in Madin-Darby canine kidney H cells via different targeting mechanisms. J Biol Chem 271:5017-5024.
    • (1996) J Biol Chem , vol.271 , pp. 5017-5024
    • Wozniak, M.1    Limbird, L.E.2
  • 37
    • 0027050601 scopus 로고
    • Activation of phospholipase C by alpha 1-adrenergic receptors is mediated by the alpha subunits of Gq family
    • Wu D, Katz A, Lee CH, and Simon MI (1992) Activation of phospholipase C by alpha 1-adrenergic receptors is mediated by the alpha subunits of Gq family. J Biol Chem 267:25798-25802.
    • (1992) J Biol Chem , vol.267 , pp. 25798-25802
    • Wu, D.1    Katz, A.2    Lee, C.H.3    Simon, M.I.4
  • 38
    • 0346668335 scopus 로고    scopus 로고
    • A novel anterograde trafficking signal present in the N-terminal extracellular domain of ionotropic glutamate receptors
    • Xia H, von Zastrow M, and Malenka RC (2002) A novel anterograde trafficking signal present in the N-terminal extracellular domain of ionotropic glutamate receptors. J Biol Chem 277:47765-47769.
    • (2002) J Biol Chem , vol.277 , pp. 47765-47769
    • Xia, H.1    Von Zastrow, M.2    Malenka, R.C.3
  • 40
    • 0032587931 scopus 로고    scopus 로고
    • Alpha1-adrenoceptor subtypes
    • Zhong H and Minneman KP (1999a) Alpha1-adrenoceptor subtypes. Eur J Pharmacol 375:261-276.
    • (1999) Eur J Pharmacol , vol.375 , pp. 261-276
    • Zhong, H.1    Minneman, K.P.2
  • 41
    • 0033012066 scopus 로고    scopus 로고
    • Differential activation of mitogen-activated protein kinase pathways in PC12 cells by closely related alpha1-adrenergic receptor subtypes
    • Zhong H and Minneman KP (1999b) Differential activation of mitogen-activated protein kinase pathways in PC12 cells by closely related alpha1-adrenergic receptor subtypes. J Neurochem 72:2388-2396.
    • (1999) J Neurochem , vol.72 , pp. 2388-2396
    • Zhong, H.1    Minneman, K.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.