The α1D-adrenergic receptor directly regulates arterial blood pressure via vasoconstriction

Journal of Clinical Investigation

Volumn 109, Issue 6, 2002, Pages 765-775

  Tanoue, Akito ^a   Nasa, Yoshihisa ^b   Koshimizu, Takaaki ^a   Shinoura, Hitomi ^a   Oshikawa, Sayuri ^a   Kawai, Takayuki ^b   Sunada, Sachie ^b   Takeoand, Satoshi ^b   Tsujimoto, Gozoh ^a  

^a NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^b TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1D ADRENERGIC RECEPTOR; CATECHOLAMINE; NORADRENALIN; PHENYLEPHRINE; RECEPTOR SUBTYPE;

ADRENERGIC SYSTEM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTERIAL PRESSURE; ARTICLE; BINDING AFFINITY; BLOOD PRESSURE; BLOOD PRESSURE MEASUREMENT; CARDIOVASCULAR FUNCTION; CATECHOLAMINE BLOOD LEVEL; ECHOCARDIOGRAPHY; GENE DISRUPTION; GENE TARGETING; GENOTYPE; HEART FUNCTION; HEART WEIGHT; HYPOTENSION; LIGAND BINDING; MEAN ARTERIAL PRESSURE; MESENTERIC ARTERY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASOCONSTRICTION;

ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN II; ANIMALS; AORTA; ARTERIES; BLOOD PRESSURE; CARDIOVASCULAR SYSTEM; FEMALE; GENE TARGETING; MALE; MICE; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; NOREPINEPHRINE; PHENYLEPHRINE; PIPERAZINES; QUINAZOLINES; RADIOLIGAND ASSAY; RECEPTORS, ADRENERGIC, ALPHA-1; SEROTONIN; TISSUE EXTRACTS; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASOPRESSINS;

EID: 0036196123     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200214001     Document Type: Article

References (50)

1. Catecholamines, sympathomimetic drugs, and adrenergic receptor antagonists
2. 1-adrenergic receptor
3. 1-adrenergic receptor subtype
4. 10- adrenergic receptor cDNA
5. 1C-adrenergic receptor
6. 1d-adrenergic receptor and inducible expression of three human subtypes in SK-N-MC cells
7. 1-adrenoceptors: Consensus update
8. 1-adrenoceptor
9. 2+ in smooth muscle
10. 1-adrenoceptors to characterize subtype selectivity of drugs for the treatment of prostatic hypertrophy
11. 1-adrenergic receptors
12. 1-adrenergic receptor regulation: Basic science and clinical implications
13. 1-adrenergic receptors: New insights and directions
14. G protein-coupled receptors: Functional and mechanistic insights through altered gene expression
15. Functional consequences of altering myocardial adrenergic receptor signaling
16. lb-adrenergic receptor
17. 1Dadrenoceptor subtype in rat myocardium, aorta and other tissues
18. 1B-adrenergic receptor
19. 1d-adrenergic receptor gene
20. The mes enchymal winged helix transcription factor Fkh6 is required for the control of gastrointestinal proliferation and differentiation
21. A novel negative selection for homologous recombinants using diphtheria toxin A fragment gene
22. Systolic blood pressure in eight inbred strains of mice
23. A single nucleotide change in the prolidase gene in fibroblasts from two patients with polypeptide positive prolidase deficiency. Expression of the mutant enzyme in NIH 3T3 cells
24. Glyceraldehyde-3-phosphate dehydrogenase mRNA is a major interleukin 2-induced transcript in a cloned T-helper lymphocyte
25. 1d-adrenergic receptor and tissue distribution of three alpha 1-adrenergic receptor subtypes in mouse
26. 1adrenoceptors and native tissues
27. A computerized system for measuring blood pressure in mice
28. Targeted disruption of the β2 adrenergic receptor gene
29. Transthoracic echocardiography in models of cardiac disease in the mouse
30. Effects of the antihypertensive agent, cicletanine, on noradrenaline release and vasoconstriction in perfused mesenteric artery of SHR
31. Ligand: A versatile computerized approach for characterization of ligand-binding systems
32. Chronic α1-adrenergic blockade increases sympathoneural but not adrenomedullary activity in patients with essential hypertension
33. 1D-adrenoceptor mediating the contractile response of rat aorta to noradrenaline
34. 1D adrenoceptor to the contraction of vascular smooth muscle
35. 1D-subtype
36. 1D-adrenoceptors in rat aorta
37. 1B adrenergic receptor and the contribution of this and the other subtypes to vascular smooth muscle contraction: Analysis with selective ligands and antisense
38. 1-adrenoceptors on vascular smooth muscle: Correlation with the regulation of contraction
39. 1-adrenergic receptors by vessel bed and age
40. Vascular adrenoceptors: An update
41. 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy
42. 1-adrenergic receptor-mediated regulation of β-adrenergic signaling
43. 1-adrenergic receptors are required for normal postnatal growth of the heart
44. 1-adrenergic receptors by vessel bed and age
45. 1A subtypes
46. 1Dadrenoceptors in the vasculature of young and adult spontaneously hypertensive rats
47. 1A-adrenoceptors in contraction
48. 1D-adrenoceptors in the rat vasculature
49. 1-adrenoreceptor subtypes in vitro and in situ
50. 1D-adrenergic receptor expression in vascular smooth muscle cells in vitro and ex vivo