Identification of the "missing domain" of the rat copper-transporting ATPase, atp7b: Insight into the structural and metal binding characteristics of its N-terminal copper-binding domain

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1688, Issue 1, 2004, Pages 78-85

  Tsay, Mike J ^a,b   Fatemi, Negah ^a,b   Narindrasorasak, Suree ^a   Forbes, John R ^c,d   Sarkar, Bibudhendra ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF ALBERTA   (Canada)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

ATP7B; Copper; Copper binding; Copper transport; Heavy metal associated domain; HMA domain; LEC rat; Long Evans Cinnamon rat; N terminal copper binding domain of the rat copper transporting ATPase (residues 1 642); RCBD; WCBD; Wilson disease

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE 7B; COPPER; DISULFIDE; IODINE DERIVATIVE; METAL; PROTEIN; UNCLASSIFIED DRUG; ZINC 65;

AMINO TERMINAL SEQUENCE; ANIMAL MODEL; ARTICLE; BINDING SITE; BLOTTING; CHEMICAL STRUCTURE; CIRCULAR DICHROISM; CONTROLLED STUDY; DISULFIDE BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN MOTIF; PROTEIN STRUCTURE; RAT; RAT STRAIN; STRUCTURAL HOMOLOGY; TECHNIQUE; ULTRAVIOLET RADIATION; WILSON DISEASE;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CATION TRANSPORT PROTEINS; CIRCULAR DICHROISM; CLONING, MOLECULAR; COPPER; DNA, COMPLEMENTARY; GENETIC VECTORS; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN STRUCTURE, TERTIARY; RATS; SEQUENCE ALIGNMENT; TRANSITION ELEMENTS; ZINC RADIOISOTOPES;

ANIMALIA; CINNAMOMUM VERUM;

EID: 1642308867     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2003.11.001     Document Type: Article

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