Expression, purification and copper-binding studies of the first metal- binding domain of Menkes protein

European Journal of Biochemistry

Volumn 264, Issue 3, 1999, Pages 890-896

  Jensen, Pia Y ^a,b,c   Bonander, Nicklas ^c   Horn, Nina ^d   Tümer, Zeynep ^e   Farver, Ole ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

^c UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^d JOHN F KENNEDY INSTITUTE   (Denmark)

^e NONE

Author keywords

Binding constant; Copper; Glutathione; Menkes protein; Molecular biology

Indexed keywords

ADENOSINE TRIPHOSPHATASE; COPPER; GLUTATHIONE; MENKES PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; ENZYME PURIFICATION; METAL BINDING; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SEQUENCE ANALYSIS;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING SITES; CARRIER PROTEINS; CATION TRANSPORT PROTEINS; CIRCULAR DICHROISM; CLONING, MOLECULAR; COPPER; CYSTEINE; DNA PRIMERS; ESCHERICHIA COLI; GENE EXPRESSION; HUMANS; KINETICS; OXIDATION-REDUCTION; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS;

EID: 0033568524     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00680.x     Document Type: Article

References (34)

1. 1. Yamaguchi, Y., Heiny, M.E., Suzuki, M. & Gitlin, J.D. (1996) Biochemical characterization and intracellular localization of the Menkes disease protein. Proc. Natl Acad. Sci. USA 93, 14030-14035.
2. 2. Dierick, H.A., Adam, A.N., Escara-Wilke, J.F. & Glover, T.W. (1997) Immunocytochemical localization of the Menkes copper transport protein (ATP7A) to the trans-Golgi network. Hum. Mol. Genet. 6, 409-416.
3. 3. Petris, M.J., Mercer, J.F.B., Culvenor, J.G., Lockhart, P., Gleeson, P.A. & Camakaris, J. (1996) Ligand-regulated transport of the Menkes copper P-type ATPase efflux pump from the Golgi apparatus to the plasma membrane: a novel mechanism of regulated trafficking. EMBO J. 15, 6084-6095.
4. 4. Tanzi, R.E., Petrukhin, K., Chernov, I., Pellequer, J.L., Wasco, W., Ross, B., Romano, D.M., Parano, E., Pavone, L., Brzustowicz, L.M., Devoto, M., Peppercorn, J., Bush, A.I., Sternlieb, I., Pirastu, M., Gusella, J.F., Evgrafov, O., Penchaszadeh, G.K., Honig, B., Edelman, I.S., Soares, M.B., Scheinberg, I.H. & Gilliam, T.C. (1993) The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene. Nat. Genet. 5, 344-350.
5. 5. Bull., P.C., Thomas, G.R., Rommens, J.M., Forbes, J.R. & Cox, D.W. (1993) The Wilson disease gene is a putative copper transporting P-type ATPase similar to the Menkes gene. Nat. Genet. 5, 327-337.
6. 6. Klomp, L.W.J., Lin, S.-J., Yuan, D.S., Klausner, R.D., Culotta, V.C. & Gitlin, J.D. (1997) Identification and functional expression of HAH1, a novel human gene involved in copper homeostasis. J. Biol. Chem. 272, 9221-9226.
7. 2+-ATPase subfamily. Yeast 11, 283-292.
8. 8. Pufahl, R.A., Singer, C.P., Peariso, K.L., Lin, S.-J., Schmidt, P.J., Fahrni, C.J., Culotta, V.C., Penner-Hahn, J.E. & O'Halloran, T.V. (1997) Metal ion chaperone function of the soluble Cu(I) receptor Atxl. Science 278, 853-856.
9. 9. Barrineau, P., Gilbert, P., Jackson, W.J., Jones, C.S., Summers, A.O. & Wisdom, S. (1984) The DNA sequence of the mercury resistance operon of the IncFII plasmid NR1. J. Mol. Appl. Genet. 2, 601-619.
10. 10. Misra, T.K., Brown, N.L., Fritzinger, D.C., Pridmore, R.D., Barnes, W.M., Haberstroh, L. & Silver, S. (1984) Mercuric ion-resistance operons of plasmid R100 and transposon Tn501: the beginning of the operon including the regulatory region and the first two structural genes. Proc. Natl Acad. Sci. USA 81, 5975-5979.
11. 11. Solioz, M., Odermatt, A. & Krapf, R. (1994) Copper pumping ATPases: common concepts in bacteria and man. FEBS Lett. 346, 44-47.
12. 12. McRee, D.E. (1998) Living with metal ions. Nat. Struct. Biol. 5, 8-10.
13. 13. DiDonato, M., Narindrasorasak, S., Forbes, J.R., Cox, D.W. & Sarkar, B. (1997) Expression, purification, and metal binding properties of the N-terminal domain from the Wilson disease putative copper-transporting ATPase (ATP7B). J. Biol. Chem. 272, 33279-33282.
14. 14. Lutsenko, S., Petrukhin, K., Cooper, M.J., Gilliam, C.T. & Kaplan, J.H. (1997) N-terminal domains of human copper-transporting adenosine triphosphatases (the Wilson's and Menkes disease proteins) bind copper selectively in vivo and in vitro with stoichiometry of one copper per metal-binding repeat. J. Biol Chem. 272, 18939-18944.
15. 15. Sahlman, L. & Jonsson, B.-H. (1992) Purification and properties of the mercuric-ion-binding protein MerP. Eur. J. Biochem. 205, 375-381.
16. 16. Ellman, G.L. (1959) Tissue sulfhydryl groups. Arch. Biochem. Biophys. 82, 70-77.
17. 17. Bradford, M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
18. 18. Felsenfeld, G. (1960) The determination of cuprous ion in copper proteins. Arch. Biochem. Biophys. 87, 247-251.
19. 19. Broman, L., Malmström, B.G., Aasa, R. & Vänngård, T. (1962) Quantative electron spin resonance studies on native and denatured ceruloplasmin and laccase. J. Mol. Biol. 5, 301-310.
20. 20. Ciriolo, M.R., Desideri, A., Paci, M. & Rotilio, G. (1990) Reconstitution of Cu,Zn-Superoxide dismutase by the Cu(I)·glutathione complex. J. Biol. Chem. 265, 11030-11034.
21. 21. Minder, W. & Stocker, E. (1936) Zur Kenntnis des Trithioharnstoff-cuprochlorids. Z. Kristallogr. 94, 137-141.
22. 22. Studier, F.W. (1991) Use of bacteriophage T7 lysozyme to improve an inducible T7 expression system. J. Mol. Biol. 219, 37-44.
23. 23. Hibino, T., Lee, B.H. & Takabe, T. (1994) Role of transit peptide sequence of plastocyanin for its expression, processing, and copper-binding activity in Escherichia coli. J. Biochem. 116, 826-832.
24. 24. Blattner, F.R., Plunkett, G., III, Bloch, C.A., Perna, N.T., Burland, V., Riley, M., Collado-Vides, J., Glasner, J.D., Rode, C.K., Mayhew, G.F., Gregor, J., Davis, N.W., Kirkpatrick, H.A., Goeden, M.A., Rose, D.J., Mau, B. & Shao, Y. (1997) The complete genome sequence of Escherichia coli K-12. Science 277, 1453-1474.
25. 25. Malmström, B.G. & Vänngård, T. (1960) Electron spin resonance of copper proteins and some model complexes. J. Mol. Biol. 2, 118-124.
26. 26. Jensen, P.Y., Bonander, N., Karlsson, B.G., Horn, N., Tümer, Z. & Farver, O. (1998) Investigation of the copper binding sites in the Menkes disease protein, ATP7A. J. Inher. Metab. Dis. 21, 195-198.
27. 27. Schechinger, T., Chapman, A., Cammack, R. & Weser, U. (1988) Sequential reconstitution of copper sites in caeruloplasmin. Inorg. Chim. Acta 151, 265-268.
28. 28. Nielson, K.B., Atkin, C.L. & Winge, D.R. (1985) Distinct metal-binding configurations in metallothionein. J. Biol. Chem. 260, 5342-5350.
29. 29. Gitschier, J., Moffat, B., Reilly, D., Wood, W.I. & Fairbrother, W.J. (1998) Solution structure of the fourth metal-binding domain from the Menkes copper-transporting ATPase. Nat. Struct. Biol. 5, 47-54.
30. 30. Ralle, M., Cooper, M.J., Lutsenko, S. & Blackburn, N.J. (1998) The Menkes disease protein binds copper via novel 2-coordinate Cu (I) -cysteinates in the N-terminal domain. J. Am. Chem. Soc. 120, 13525-13526.
31. 31. Steele, R.A. & Opella, S.J. (1997) Structures of the reduced and mercury-bound forms of MerP, the periplasmic protein from the bacterial mercury detoxification system. Biochemistry 36, 6885-6895.
32. 32. Creighton, T.E. (1993). Proteins - Structures and Molecular Properties. 2nd edn. W. H. Freeman, New York.
33. 33. Tümer, Z. & Horn, N. (1996) Menkes disease: recent advances and new insights into copper metabolism. Ann. Med. 28, 121-129.
34. 34. Payne, A.S. & Gitlin, J.D. (1998) Functional expression of the Menkes disease protein reveals common biochemical mechanisms among the copper-transporting P-type ATPases. J. Biol. Chem. 273, 3765-3770.