메뉴 건너뛰기




Volumn 71, Issue 4, 1998, Pages 1577-1587

Cellular localization and temporal elevation of tumor necrosis factor- α, interleukin-1α, and transforming growth factor-β1 mRNA in hippocampal injury response induced by trimethyltin

Author keywords

Hippocampus; Interleukin 1 2 ; Microglia; Transforming growth factor ; Trimethyltin; Tumor necrosis factor

Indexed keywords

CD11B ANTIGEN; GAMMA INTERFERON; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1ALPHA; MESSENGER RNA; NITRIC OXIDE SYNTHASE; TRANSFORMING GROWTH FACTOR BETA1; TRIMETHYLTIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 0031661172     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.71041577.x     Document Type: Article
Times cited : (82)

References (54)
  • 1
    • 0024404853 scopus 로고
    • IL-6 inhibits lipopolysaccharide-induced tumor necrosis factor production in cultured human monocytes, U937 cells, and in mice
    • Aderka D., Le J. M., and Vilcek J. (1989) IL-6 inhibits lipopolysaccharide-induced tumor necrosis factor production in cultured human monocytes, U937 cells, and in mice. J. Immunol. 143, 3517-3523.
    • (1989) J. Immunol. , vol.143 , pp. 3517-3523
    • Aderka, D.1    Le, J.M.2    Vilcek, J.3
  • 2
    • 0025285859 scopus 로고
    • Cytokines: Coordinators of immune and inflammatory responses
    • Arai K., Lee F., Miyajima A., and Miyatake S. (1990) Cytokines: coordinators of immune and inflammatory responses. Annu. Rev. Biochem. 59, 783-836.
    • (1990) Annu. Rev. Biochem. , vol.59 , pp. 783-836
    • Arai, K.1    Lee, F.2    Miyajima, A.3    Miyatake, S.4
  • 3
    • 0026638409 scopus 로고
    • Inflammatory cytokines within the central nervous system: Sources, function, and mechanisms of action
    • Benveniste E. N. (1992) Inflammatory cytokines within the central nervous system: sources, function, and mechanisms of action. Am. J. Physiol. 263, C1-C16.
    • (1992) Am. J. Physiol. , vol.263
    • Benveniste, E.N.1
  • 5
    • 0018627342 scopus 로고
    • The behavioural and neuropathologic sequelae of intoxication by trimethyltin compounds in the rat
    • Brown A. W., Aldridge W. N., Street B. W., and Verschoyle R. D. (1979) The behavioural and neuropathologic sequelae of intoxication by trimethyltin compounds in the rat. Am. J. Pathol. 97, 59-81.
    • (1979) Am. J. Pathol. , vol.97 , pp. 59-81
    • Brown, A.W.1    Aldridge, W.N.2    Street, B.W.3    Verschoyle, R.D.4
  • 6
    • 0025106662 scopus 로고
    • Cellular and molecular mechanisms that direct leukocyte traffic
    • Butcher E. C. (1990) Cellular and molecular mechanisms that direct leukocyte traffic. Am. J. Pathol. 136, 621-636.
    • (1990) Am. J. Pathol. , vol.136 , pp. 621-636
    • Butcher, E.C.1
  • 7
    • 0028203591 scopus 로고
    • Activation of cerebral cytokine gene expression and its correlation with onset of reactive astrocyte and acute-phase response gene expression in scrapie
    • Campbell I. L., Eddleston M., Kemper P., Oldstone M. B. S. A., and Hobbs M. V. (1994) Activation of cerebral cytokine gene expression and its correlation with onset of reactive astrocyte and acute-phase response gene expression in scrapie. J. Virol. 68, 2383-2387.
    • (1994) J. Virol. , vol.68 , pp. 2383-2387
    • Campbell, I.L.1    Eddleston, M.2    Kemper, P.3    Oldstone, M.B.S.A.4    Hobbs, M.V.5
  • 10
    • 0027221653 scopus 로고
    • Nitric oxide synthase induction in glial cells: Effect on neuronal survival
    • Demerle P. C., Lonchampt M. O., Chabrier P. E., and Braquet P. (1993) Nitric oxide synthase induction in glial cells: effect on neuronal survival. Life Sci. 2, 1883-1890.
    • (1993) Life Sci. , vol.2 , pp. 1883-1890
    • Demerle, P.C.1    Lonchampt, M.O.2    Chabrier, P.E.3    Braquet, P.4
  • 11
    • 0025311615 scopus 로고
    • Macrophage deactivating factor and transforming growth factors-β1, -β2, and -β3 inhibit induction of macrophage nitrogen oxide synthesis by IFN-γ
    • Ding A., Nathan C. F., Graycar J., Derynck R., Stuher D. J., and Srimal S. (1990) Macrophage deactivating factor and transforming growth factors-β1, -β2, and -β3 inhibit induction of macrophage nitrogen oxide synthesis by IFN-γ. J. Immunol. 145, 940-944.
    • (1990) J. Immunol. , vol.145 , pp. 940-944
    • Ding, A.1    Nathan, C.F.2    Graycar, J.3    Derynck, R.4    Stuher, D.J.5    Srimal, S.6
  • 12
    • 0027354292 scopus 로고
    • Microglial MHC antigen expression after ischemic and kainic acid lesions of the adult rat hippocampus
    • Finsen B. R., Jorgensen M. B., Diemer N. H., and Zimmer J. (1993) Microglial MHC antigen expression after ischemic and kainic acid lesions of the adult rat hippocampus. Glia 7, 41-49.
    • (1993) Glia , vol.7 , pp. 41-49
    • Finsen, B.R.1    Jorgensen, M.B.2    Diemer, N.H.3    Zimmer, J.4
  • 14
    • 0026218081 scopus 로고
    • Expression of tumor necrosis factor-α in the developing nervous system
    • Gendron R., Nestel F., Lapp W., and Baines M. (1991) Expression of tumor necrosis factor-α in the developing nervous system. Int. J. Neurosci. 60, 129-136.
    • (1991) Int. J. Neurosci. , vol.60 , pp. 129-136
    • Gendron, R.1    Nestel, F.2    Lapp, W.3    Baines, M.4
  • 15
    • 0027343152 scopus 로고
    • Microglial secretion products and their impact on the nervous system
    • Giulian D. and Corpuz M. (1993) Microglial secretion products and their impact on the nervous system. Adv. Neurol. 59, 315-320.
    • (1993) Adv. Neurol. , vol.59 , pp. 315-320
    • Giulian, D.1    Corpuz, M.2
  • 16
    • 0021912473 scopus 로고
    • Interleukin-1 stimulation of astroglial proliferation after brain injury
    • Giulian D. and Lachman L. B. (1985) Interleukin-1 stimulation of astroglial proliferation after brain injury. Science 228, 497-499.
    • (1985) Science , vol.228 , pp. 497-499
    • Giulian, D.1    Lachman, L.B.2
  • 17
    • 0023772364 scopus 로고
    • Interleukin-1 injected into mammalian brain stimulates astrogliosis and neurovascularization
    • Giulian D., Woodward J., Young D. G., Krebs J. F., and Lachman L. B. (1988) Interleukin-1 injected into mammalian brain stimulates astrogliosis and neurovascularization. J. Neurosci. 8, 2488-2490.
    • (1988) J. Neurosci. , vol.8 , pp. 2488-2490
    • Giulian, D.1    Woodward, J.2    Young, D.G.3    Krebs, J.F.4    Lachman, L.B.5
  • 18
    • 0027463358 scopus 로고
    • Brain glia release factors with opposing actions on neuronal survival
    • Giulian D., Vaca K., and Corpuz M. (1993) Brain glia release factors with opposing actions on neuronal survival. J. Neurosci. 13, 29-37.
    • (1993) J. Neurosci. , vol.13 , pp. 29-37
    • Giulian, D.1    Vaca, K.2    Corpuz, M.3
  • 19
    • 0028596581 scopus 로고
    • The impact of microglia-derived cytokines upon gliosis in the CNS
    • Giulian D., Jun L., Xia L., Johnson G., and Rutecki P. A. (1994) The impact of microglia-derived cytokines upon gliosis in the CNS. Dev. Neurosci. 16, 128-136.
    • (1994) Dev. Neurosci. , vol.16 , pp. 128-136
    • Giulian, D.1    Jun, L.2    Xia, L.3    Johnson, G.4    Rutecki, P.A.5
  • 20
    • 0021966647 scopus 로고
    • The use of synapsin I as a biochemical marker for neuronal damage
    • Harry G. J., Goodrum J. F., Krigman M. R., and Morell P. (1985) The use of synapsin I as a biochemical marker for neuronal damage. Brain Res. 326, 9-18.
    • (1985) Brain Res. , vol.326 , pp. 9-18
    • Harry, G.J.1    Goodrum, J.F.2    Krigman, M.R.3    Morell, P.4
  • 22
    • 0025042430 scopus 로고
    • Delayed increases in regional brain quinolinic acid follow transient ischemia in the gerbil
    • Heyes M. P. and Nowak T. J. (1990) Delayed increases in regional brain quinolinic acid follow transient ischemia in the gerbil. J. Cereb. Blood Flow Metab. 10, 660-667.
    • (1990) J. Cereb. Blood Flow Metab. , vol.10 , pp. 660-667
    • Heyes, M.P.1    Nowak, T.J.2
  • 23
    • 0029990827 scopus 로고    scopus 로고
    • Cellular and molecular correlates to plasticity during recovery from injury in the developing mammalian brain
    • Ide C. F., Scripter J. L., Coltman B. W., Dotson R. S., Snyder R. S., and Jelaso A. (1996) Cellular and molecular correlates to plasticity during recovery from injury in the developing mammalian brain. Prog. Brain Res. 108, 365-377.
    • (1996) Prog. Brain Res. , vol.108 , pp. 365-377
    • Ide, C.F.1    Scripter, J.L.2    Coltman, B.W.3    Dotson, R.S.4    Snyder, R.S.5    Jelaso, A.6
  • 24
    • 0025943056 scopus 로고
    • Isolation of two cDNAs encoding novel α1 antichymotrypsin-like proteins in a murine chondrocytic cell line
    • Inglis J. D., Lee M., Davidson D. R., and Hill R. E. (1991) Isolation of two cDNAs encoding novel α1 antichymotrypsin-like proteins in a murine chondrocytic cell line. Gene 106, 213-222.
    • (1991) Gene , vol.106 , pp. 213-222
    • Inglis, J.D.1    Lee, M.2    Davidson, D.R.3    Hill, R.E.4
  • 26
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • Kreutzberg G. W. (1996) Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 19, 312-318.
    • (1996) Trends Neurosci. , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 27
    • 0028177321 scopus 로고
    • Transforming growth factor-beta 1 induces neuronal and astrocyte genes: Tubulin alpha 1, glial fibrillary acidic protein and clusterin
    • Laping N. J., Morgan T. E., Nichols N. R., Rozovsky I., Young Chan C., Zarow C., and Finch C. E. (1994) Transforming growth factor-beta 1 induces neuronal and astrocyte genes: tubulin alpha 1, glial fibrillary acidic protein and clusterin. Neuroscience 58, 563-572.
    • (1994) Neuroscience , vol.58 , pp. 563-572
    • Laping, N.J.1    Morgan, T.E.2    Nichols, N.R.3    Rozovsky, I.4    Young Chan, C.5    Zarow, C.6    Finch, C.E.7
  • 28
    • 0027450149 scopus 로고
    • The possible contribution of microglia and macrophages to delayed neuronal death after ischemia
    • Lees G. J. (1993) The possible contribution of microglia and macrophages to delayed neuronal death after ischemia. J. Neurol. Sci. 114, 119-122.
    • (1993) J. Neurol. Sci. , vol.114 , pp. 119-122
    • Lees, G.J.1
  • 29
    • 0026590273 scopus 로고
    • TGF-βI expression is initiated in adult auditory neurons by sectioning of the auditory nerve
    • Lefebvre P. P., Martin D., Staecker H., Weber T., Moonen G., and Van De Water T. R. (1992) TGF-βI expression is initiated in adult auditory neurons by sectioning of the auditory nerve. Neuroreport 3, 295-298.
    • (1992) Neuroreport , vol.3 , pp. 295-298
    • Lefebvre, P.P.1    Martin, D.2    Staecker, H.3    Weber, T.4    Moonen, G.5    Van De Water, T.R.6
  • 30
    • 0026510668 scopus 로고
    • Transforming growth factor-β1 in the rat brain: Increase after injury and inhibition of astrocyte proliferation
    • Lindholm D., Castren E., Kiefer R., Zafra F., and Thoenen H. (1992) Transforming growth factor-β1 in the rat brain: increase after injury and inhibition of astrocyte proliferation. J. Cell Biol. 117, 395-400.
    • (1992) J. Cell Biol. , vol.117 , pp. 395-400
    • Lindholm, D.1    Castren, E.2    Kiefer, R.3    Zafra, F.4    Thoenen, H.5
  • 31
    • 0029956457 scopus 로고    scopus 로고
    • Regulation of microglial activation by TGF-beta, IL-10 and CSF-1
    • Lodge P. A. and Siram S. (1996) Regulation of microglial activation by TGF-beta, IL-10 and CSF-1. J. Leukocyte Biol. 60, 502-508.
    • (1996) J. Leukocyte Biol. , vol.60 , pp. 502-508
    • Lodge, P.A.1    Siram, S.2
  • 32
    • 0026699984 scopus 로고
    • Enhanced expression of transforming growth factor beta 1 in the rat brain after localized cerebral injury
    • Logan A., Frautschy S. A., Gonzalez A. M., Sporn M. B., and Baird A. (1992) Enhanced expression of transforming growth factor beta 1 in the rat brain after localized cerebral injury. Brain Res. 587, 216-225.
    • (1992) Brain Res. , vol.587 , pp. 216-225
    • Logan, A.1    Frautschy, S.A.2    Gonzalez, A.M.3    Sporn, M.B.4    Baird, A.5
  • 33
    • 0029013291 scopus 로고
    • Trimethyltin increases interleukin (IL)-1α, IL-6, and tumor necrosis factor-α mRNA levels in rat hippocampus
    • Maier W. E., Brown H. W., Tilson H. A., Luster M. I., and Harry G. J. (1995) Trimethyltin increases interleukin (IL)-1α, IL-6, and tumor necrosis factor-α mRNA levels in rat hippocampus. J. Neuroimmunol. 59, 65-75.
    • (1995) J. Neuroimmunol. , vol.59 , pp. 65-75
    • Maier, W.E.1    Brown, H.W.2    Tilson, H.A.3    Luster, M.I.4    Harry, G.J.5
  • 34
    • 0029994596 scopus 로고    scopus 로고
    • Differential activation of microglia and astrocytes following trimethyltin-induced neurodegeneration
    • McCann M. J., O'Callaghan J. P., Martin P. M., Bertram T., and Streit W. J. (1996) Differential activation of microglia and astrocytes following trimethyltin-induced neurodegeneration. Neuroscience 72, 273-281.
    • (1996) Neuroscience , vol.72 , pp. 273-281
    • McCann, M.J.1    O'Callaghan, J.P.2    Martin, P.M.3    Bertram, T.4    Streit, W.J.5
  • 35
    • 0030221758 scopus 로고    scopus 로고
    • Cytokines in inflammatory brain lesions: Helpful and harmful
    • Merrill J. E. and Benveniste E. N. (1996) Cytokines in inflammatory brain lesions: helpful and harmful. Trends Neurosci. 19, 331-338.
    • (1996) Trends Neurosci. , vol.19 , pp. 331-338
    • Merrill, J.E.1    Benveniste, E.N.2
  • 36
    • 0026037661 scopus 로고
    • Natural and induced cytotoxicity of oligodendrocytes by microglia is inhabitable by TGF beta
    • Merrill J. E. and Zimmerman R. P. (1991) Natural and induced cytotoxicity of oligodendrocytes by microglia is inhabitable by TGF beta. Glia 4, 327-331.
    • (1991) Glia , vol.4 , pp. 327-331
    • Merrill, J.E.1    Zimmerman, R.P.2
  • 37
    • 0027161216 scopus 로고
    • Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide
    • Merrill J. E., Ignarro L. J., Sherman M. P., Melinek J., and Lane T. E. (1993) Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide. J. Immunol. 151, 2132-2141.
    • (1993) J. Immunol. , vol.151 , pp. 2132-2141
    • Merrill, J.E.1    Ignarro, L.J.2    Sherman, M.P.3    Melinek, J.4    Lane, T.E.5
  • 38
    • 0027212063 scopus 로고
    • TGF-beta 1 mRNA increases in macrophage/microglial cells of the hippocampus in response to deafferentation and kainic acid-induced neurodegeneration
    • Morgan T. E., Nichols N. R., Pasinetti G. M., and Finch C. E. (1993) TGF-beta 1 mRNA increases in macrophage/microglial cells of the hippocampus in response to deafferentation and kainic acid-induced neurodegeneration. Exp. Neurol. 120, 291-301.
    • (1993) Exp. Neurol. , vol.120 , pp. 291-301
    • Morgan, T.E.1    Nichols, N.R.2    Pasinetti, G.M.3    Finch, C.E.4
  • 39
    • 0026065039 scopus 로고
    • Increases in transforming growth factor-β mRNA in hippocampus during response to entorhinal cortex lesions in intact and adrenalectomized rats
    • Nichols N. R., Laping N. J., Day J. R., and Finch C. E. (1991) Increases in transforming growth factor-β mRNA in hippocampus during response to entorhinal cortex lesions in intact and adrenalectomized rats. J. Neurosci. Res. 28, 134-139.
    • (1991) J. Neurosci. Res. , vol.28 , pp. 134-139
    • Nichols, N.R.1    Laping, N.J.2    Day, J.R.3    Finch, C.E.4
  • 40
    • 0028293559 scopus 로고
    • Signal transduction pathways mediating astrocyte IL-6 induction by IL-1 beta and tumor necrosis factor-alpha
    • Norris J. G., Tang L. P., Sparacio S. M., and Benveniste E. N. (1994) Signal transduction pathways mediating astrocyte IL-6 induction by IL-1 beta and tumor necrosis factor-alpha. J. Immunol. 152, 841-850.
    • (1994) J. Immunol. , vol.152 , pp. 841-850
    • Norris, J.G.1    Tang, L.P.2    Sparacio, S.M.3    Benveniste, E.N.4
  • 41
    • 0027289474 scopus 로고
    • Transforming growth factor beta 1 and fibronectin messenger RNA in rat brain: Responses to injury and cell-type localization
    • Pasinetti G. M., Nichols N. R., Tocco G., Morgan T., Laping N., and Finch C. E. (1993) Transforming growth factor beta 1 and fibronectin messenger RNA in rat brain: responses to injury and cell-type localization. Neuroscience 54, 893-907.
    • (1993) Neuroscience , vol.54 , pp. 893-907
    • Pasinetti, G.M.1    Nichols, N.R.2    Tocco, G.3    Morgan, T.4    Laping, N.5    Finch, C.E.6
  • 42
    • 0020644334 scopus 로고
    • Developmental effects of trimethyltin intoxication in the neonatal mouse. I. Light microscopic studies
    • Reuhl K. R., Smallridge E. A., Chang L. W., and Mackenzie B. A. (1983) Developmental effects of trimethyltin intoxication in the neonatal mouse. I. Light microscopic studies. Neurotoxicology 4, 19-28.
    • (1983) Neurotoxicology , vol.4 , pp. 19-28
    • Reuhl, K.R.1    Smallridge, E.A.2    Chang, L.W.3    Mackenzie, B.A.4
  • 44
    • 0028869476 scopus 로고
    • Cytokines and the nervous system. II: Actions and mechanisms of action
    • Rothwell N. J. and Hopkins S. J. (1995) Cytokines and the nervous system. II: Actions and mechanisms of action. Trends Neurosci. 18, 130-136.
    • (1995) Trends Neurosci. , vol.18 , pp. 130-136
    • Rothwell, N.J.1    Hopkins, S.J.2
  • 45
    • 0029925745 scopus 로고    scopus 로고
    • Cytokines and their receptors in the central nervous system: Physiology, pharmacology, and pathology
    • Rothwell N. J., Luheshi G., and Toulmond S. (1996) Cytokines and their receptors in the central nervous system: physiology, pharmacology, and pathology. Pharmacol. Ther. 69, 85-95.
    • (1996) Pharmacol. Ther. , vol.69 , pp. 85-95
    • Rothwell, N.J.1    Luheshi, G.2    Toulmond, S.3
  • 46
    • 0023691651 scopus 로고
    • Induction of neuronal differentiation in PC12 cells by B-cell stimulatory factor 2/interleukin 6
    • Satoh T., Nakamura S., Taga T., Matsuda T., Hirano T., Kishimoto T., and Kaziro Y. (1988) Induction of neuronal differentiation in PC12 cells by B-cell stimulatory factor 2/interleukin 6. Mol. Cell. Biol. 8, 3546-3549.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 3546-3549
    • Satoh, T.1    Nakamura, S.2    Taga, T.3    Matsuda, T.4    Hirano, T.5    Kishimoto, T.6    Kaziro, Y.7
  • 47
    • 0025275946 scopus 로고
    • Transforming growth factors type beta 1 and beta 2 suppress rat astrocyte autoantigen presentation and antagonize hyperinduction of class II major histocompatibility complex antigen expression by interferon-gamma and tumor necrosis factor-alpha
    • Schluesener H. J. (1990) Transforming growth factors type beta 1 and beta 2 suppress rat astrocyte autoantigen presentation and antagonize hyperinduction of class II major histocompatibility complex antigen expression by interferon-gamma and tumor necrosis factor-alpha. J. Neuroimmunol. 27, 41-47.
    • (1990) J. Neuroimmunol. , vol.27 , pp. 41-47
    • Schluesener, H.J.1
  • 48
    • 0025092159 scopus 로고
    • Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor
    • Selmaj K. W., Farooq M., Norton W. T., Raine C. S., and Brosnan C. F. (1990) Proliferation of astrocytes in vitro in response to cytokines. A primary role for tumor necrosis factor. J. Immunol. 144, 129-135.
    • (1990) J. Immunol. , vol.144 , pp. 129-135
    • Selmaj, K.W.1    Farooq, M.2    Norton, W.T.3    Raine, C.S.4    Brosnan, C.F.5
  • 49
    • 0026463554 scopus 로고
    • Nitric oxide-mediated neuronal injury in multiple sclerosis
    • Sherman M. P., Griscavage J. M., and Ignarro L. J. (1992) Nitric oxide-mediated neuronal injury in multiple sclerosis. Med. Hypotheses 39, 143-146.
    • (1992) Med. Hypotheses , vol.39 , pp. 143-146
    • Sherman, M.P.1    Griscavage, J.M.2    Ignarro, L.J.3
  • 50
    • 0023213595 scopus 로고
    • Lectin binding by resting and reactive microglia
    • Streit W. J. and Kreutzberg G. W. (1987) Lectin binding by resting and reactive microglia. J. Neurocytol. 16, 249-260.
    • (1987) J. Neurocytol. , vol.16 , pp. 249-260
    • Streit, W.J.1    Kreutzberg, G.W.2
  • 51
    • 0027251338 scopus 로고
    • Influence of interleukin-1 and tumor necrosis factor alpha on the growth of microglial cells in primary cultures of mouse cerebral cortex: Involvement of colony stimulating factor-1
    • Thery C. and Mallat M. (1993) Influence of interleukin-1 and tumor necrosis factor alpha on the growth of microglial cells in primary cultures of mouse cerebral cortex: involvement of colony stimulating factor-1. Neurosci. Lett. 150, 195-199.
    • (1993) Neurosci. Lett. , vol.150 , pp. 195-199
    • Thery, C.1    Mallat, M.2
  • 52
    • 0028031990 scopus 로고
    • Interleukin-6 as an anti-inflammatory cytokine: Induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55
    • Tilg H., Trehu E., Atkins M. B., Dinarello C. A., and Mier J. W. (1994) Interleukin-6 as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55. Blood 83, 113-118.
    • (1994) Blood , vol.83 , pp. 113-118
    • Tilg, H.1    Trehu, E.2    Atkins, M.B.3    Dinarello, C.A.4    Mier, J.W.5
  • 53
    • 0025820808 scopus 로고
    • Detection of interleukin-1 and interleukin-6 in adult rat brain, following mechanical injury, by in vivo microdialysis: Evidence of a role for microglia in cytokine production
    • Woodroofe M. N., Sarna G. S., Wadhwa M., Hayes G. M., Loughlin A. J., Tinker A., and Cuzner M. L. (1991) Detection of interleukin-1 and interleukin-6 in adult rat brain, following mechanical injury, by in vivo microdialysis: evidence of a role for microglia in cytokine production. J. Neuroimmunol. 33, 227-236.
    • (1991) J. Neuroimmunol. , vol.33 , pp. 227-236
    • Woodroofe, M.N.1    Sarna, G.S.2    Wadhwa, M.3    Hayes, G.M.4    Loughlin, A.J.5    Tinker, A.6    Cuzner, M.L.7
  • 54
    • 0027296611 scopus 로고
    • In situ hybridization study of interleukin-1 beta mRNA induced by kainic acid in the rat brain
    • Yabuuchi K., Minami M., Katsumata S., and Satoh M. (1993) In situ hybridization study of interleukin-1 beta mRNA induced by kainic acid in the rat brain. Brain Res. Mol. Brain Res. 20, 153-161.
    • (1993) Brain Res. Mol. Brain Res. , vol.20 , pp. 153-161
    • Yabuuchi, K.1    Minami, M.2    Katsumata, S.3    Satoh, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.