-
1
-
-
0033843626
-
Towards 3D structures of G protein-coupled receptors: A multidisciplinary approach
-
G. Muller Towards 3D structures of G protein-coupled receptors: a multidisciplinary approach Curr. Med. Chem. 7 2000 861 888
-
(2000)
Curr. Med. Chem.
, vol.7
, pp. 861-888
-
-
Muller, G.1
-
3
-
-
0025249842
-
Membrane protein folding and oligomerization: The two-stage model
-
J.L. Popot, and D.M. Engelman Membrane protein folding and oligomerization: the two-stage model Biochemistry 29 1990 4031 4037
-
(1990)
Biochemistry
, vol.29
, pp. 4031-4037
-
-
Popot, J.L.1
Engelman, D.M.2
-
4
-
-
0030904764
-
Intermediates in the assembly of bacteriorhodopsin investigated by time-resolved absorption spectroscopy
-
P.J. Booth, and A. Farooq Intermediates in the assembly of bacteriorhodopsin investigated by time-resolved absorption spectroscopy Eur. J. Biochem. 246 1997 674 680
-
(1997)
Eur. J. Biochem.
, vol.246
, pp. 674-680
-
-
Booth, P.J.1
Farooq, A.2
-
5
-
-
2342646040
-
Probing the energy landscape of the membrane protein bacteriorhodopsin
-
H. Janovjak Probing the energy landscape of the membrane protein bacteriorhodopsin Structure (Camb) 12 2004 871 879
-
(2004)
Structure (Camb)
, vol.12
, pp. 871-879
-
-
Janovjak, H.1
-
6
-
-
0042931286
-
Sequence motifs, polar interactions and conformational changes in helical membrane proteins
-
A.R. Curran, and D.M. Engelman Sequence motifs, polar interactions and conformational changes in helical membrane proteins Curr. Opin. Struct. Biol. 13 2003 412 417
-
(2003)
Curr. Opin. Struct. Biol.
, vol.13
, pp. 412-417
-
-
Curran, A.R.1
Engelman, D.M.2
-
7
-
-
0030932407
-
A transmembrane helix dimer: Structure and implications
-
K.R. MacKenzie A transmembrane helix dimer: structure and implications Science 276 1997 131 133
-
(1997)
Science
, vol.276
, pp. 131-133
-
-
MacKenzie, K.R.1
-
8
-
-
0036226583
-
Comparison of helix interactions in membrane and soluble alpha-bundle proteins
-
M. Eilers Comparison of helix interactions in membrane and soluble alpha-bundle proteins Biophys. J. 82 2002 2720 2736
-
(2002)
Biophys. J.
, vol.82
, pp. 2720-2736
-
-
Eilers, M.1
-
9
-
-
0037174606
-
Beta2 adrenergic receptor activation. Modulation of the proline kink in transmembrane 6 by a rotamer toggle switch
-
L. Shi Beta2 adrenergic receptor activation. Modulation of the proline kink in transmembrane 6 by a rotamer toggle switch J. Biol. Chem. 277 2002 40989 40996
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 40989-40996
-
-
Shi, L.1
-
10
-
-
0034051478
-
Folding and assembly of rhodopsin from expressed fragments
-
K.D. Ridge, and N.G. Abdulaev Folding and assembly of rhodopsin from expressed fragments Methods Enzymol. 315 2000 59 70
-
(2000)
Methods Enzymol.
, vol.315
, pp. 59-70
-
-
Ridge, K.D.1
Abdulaev, N.G.2
-
11
-
-
0035942215
-
Structure and function in rhodopsin: Mass spectrometric identification of the abnormal intradiscal disulfide bond in misfolded retinitis pigmentosa mutants
-
J. Hwa Structure and function in rhodopsin: mass spectrometric identification of the abnormal intradiscal disulfide bond in misfolded retinitis pigmentosa mutants Proc. Natl. Acad. Sci. U. S. A. 98 2001 4872 4876
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 4872-4876
-
-
Hwa, J.1
-
12
-
-
0242657348
-
Membrane protein folding: Beyond the two stage model
-
D.M. Engelman Membrane protein folding: beyond the two stage model FEBS Lett. 555 2003 122 125
-
(2003)
FEBS Lett.
, vol.555
, pp. 122-125
-
-
Engelman, D.M.1
-
13
-
-
0037197848
-
Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography
-
T. Okada Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography Proc. Natl. Acad. Sci. U. S. A. 99 2002 5982 5987
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 5982-5987
-
-
Okada, T.1
-
14
-
-
2442548750
-
Identification of core amino acids stabilizing rhodopsin
-
A.J. Rader Identification of core amino acids stabilizing rhodopsin Proc. Natl. Acad. Sci. U. S. A. 101 2004 7246 7251
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 7246-7251
-
-
Rader, A.J.1
-
15
-
-
18244364614
-
Long-range interactions within a nonnative protein
-
J. Klein-Seetharaman Long-range interactions within a nonnative protein Science 295 2002 1719 1722
-
(2002)
Science
, vol.295
, pp. 1719-1722
-
-
Klein-Seetharaman, J.1
-
16
-
-
1942436349
-
The archaeal sensory rhodopsin II/transducer complex: A model for transmembrane signal transfer
-
J.P. Klare The archaeal sensory rhodopsin II/transducer complex: a model for transmembrane signal transfer FEBS Lett. 564 2004 219 224
-
(2004)
FEBS Lett.
, vol.564
, pp. 219-224
-
-
Klare, J.P.1
-
17
-
-
0026315513
-
Three-dimensional structures of the ligand-binding domain of the bacterial aspartate receptor with and without a ligand
-
M.V. Milburn Three-dimensional structures of the ligand-binding domain of the bacterial aspartate receptor with and without a ligand Science 254 1991 1342 1347
-
(1991)
Science
, vol.254
, pp. 1342-1347
-
-
Milburn, M.V.1
-
18
-
-
0037015619
-
Molecular basis of transmembrane signalling by sensory rhodopsin II-transducer complex
-
V.I. Gordeliy Molecular basis of transmembrane signalling by sensory rhodopsin II-transducer complex Nature 419 2002 484 487
-
(2002)
Nature
, vol.419
, pp. 484-487
-
-
Gordeliy, V.I.1
-
19
-
-
0001690764
-
Four-helical-bundle structure of the cytoplasmic domain of a serine chemotaxis receptor
-
K.K. Kim Four-helical-bundle structure of the cytoplasmic domain of a serine chemotaxis receptor Nature 400 1999 787 792
-
(1999)
Nature
, vol.400
, pp. 787-792
-
-
Kim, K.K.1
-
20
-
-
0033931244
-
Structure of a conserved receptor domain that regulates kinase activity: The cytoplasmic domain of bacterial taxis receptors
-
J.J. Falke, and S.H. Kim Structure of a conserved receptor domain that regulates kinase activity: the cytoplasmic domain of bacterial taxis receptors Curr. Opin. Struct. Biol. 10 2000 462 469
-
(2000)
Curr. Opin. Struct. Biol.
, vol.10
, pp. 462-469
-
-
Falke, J.J.1
Kim, S.H.2
-
21
-
-
0028175609
-
Frozen″ dynamic dimer model for transmembrane signaling in bacterial chemotaxis receptors
-
S.H. Kim Frozen″ dynamic dimer model for transmembrane signaling in bacterial chemotaxis receptors Protein Sci. 3 1994 159 165
-
(1994)
Protein Sci.
, vol.3
, pp. 159-165
-
-
Kim, S.H.1
-
22
-
-
0028845410
-
A model for transmembrane signalling by the aspartate receptor based on random-cassette mutagenesis and site-directed disulfide cross-linking
-
I.N. Maruyama A model for transmembrane signalling by the aspartate receptor based on random-cassette mutagenesis and site-directed disulfide cross-linking J. Mol. Biol. 253 1995 530 546
-
(1995)
J. Mol. Biol.
, vol.253
, pp. 530-546
-
-
Maruyama, I.N.1
-
23
-
-
0029970581
-
The cytoplasmic fragment of the aspartate receptor displays globally dynamic behavior
-
S.K. Seeley The cytoplasmic fragment of the aspartate receptor displays globally dynamic behavior Biochemistry 35 1996 5199 5206
-
(1996)
Biochemistry
, vol.35
, pp. 5199-5206
-
-
Seeley, S.K.1
-
24
-
-
0028964334
-
Reversible dissociation and unfolding of the Escherichia coli aspartate receptor cytoplasmic fragment
-
J. Wu Reversible dissociation and unfolding of the Escherichia coli aspartate receptor cytoplasmic fragment Biochemistry 34 1995 3056 3065
-
(1995)
Biochemistry
, vol.34
, pp. 3056-3065
-
-
Wu, J.1
-
25
-
-
17944394278
-
Signaling receptome: A genomic and evolutionary perspective of plasma membrane receptors involved in signal transduction
-
I. Ben-Shlomo Signaling receptome: a genomic and evolutionary perspective of plasma membrane receptors involved in signal transduction Sci STKE 2003 2003 RE9
-
(2003)
Sci STKE
, vol.2003
, pp. 9
-
-
Ben-Shlomo, I.1
-
26
-
-
0034948696
-
Structural mimicry in G protein-coupled receptors: Implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors
-
J.A. Ballesteros Structural mimicry in G protein-coupled receptors: implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors Mol. Pharmacol. 60 2001 1 19
-
(2001)
Mol. Pharmacol.
, vol.60
, pp. 1-19
-
-
Ballesteros, J.A.1
-
27
-
-
0037020303
-
Dynamics in rhodopsin
-
J. Klein-Seetharaman Dynamics in rhodopsin Chembiochem 3 2002 981 986
-
(2002)
Chembiochem
, vol.3
, pp. 981-986
-
-
Klein-Seetharaman, J.1
-
28
-
-
0037285444
-
Rhodopsin structure, dynamics, and activation: A perspective from crystallography, site-directed spin labeling, sulfhydryl reactivity, and disulfide cross-linking
-
W.L. Hubbell Rhodopsin structure, dynamics, and activation: a perspective from crystallography, site-directed spin labeling, sulfhydryl reactivity, and disulfide cross-linking Adv. Protein Chem. 63 2003 243 290
-
(2003)
Adv. Protein Chem.
, vol.63
, pp. 243-290
-
-
Hubbell, W.L.1
-
29
-
-
0034718925
-
Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor
-
N. Kunishima Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor Nature 407 2000 971 977
-
(2000)
Nature
, vol.407
, pp. 971-977
-
-
Kunishima, N.1
-
30
-
-
0034464742
-
Uncovering molecular mechanisms involved in activation of G protein-coupled receptors
-
U. Gether Uncovering molecular mechanisms involved in activation of G protein-coupled receptors Endocr. Rev. 21 2000 90 113
-
(2000)
Endocr. Rev.
, vol.21
, pp. 90-113
-
-
Gether, U.1
-
31
-
-
85030815415
-
Structure and dynamics of G protein coupled receptors
-
(Lundstrom, K. and Chiu, M., eds), Dekker Publishers (in press)
-
Klein-Seetharaman, J. and Loewen, M.C. Structure and dynamics of G protein coupled receptors. In GPCRs in Drug Discovery (Lundstrom, K. and Chiu, M., eds), Dekker Publishers (in press)
-
GPCRs in Drug Discovery
-
-
Klein-Seetharaman, J.1
Loewen, M.C.2
-
32
-
-
0034644539
-
Cell signaling by receptor tyrosine kinases
-
J. Schlessinger Cell signaling by receptor tyrosine kinases Cell 103 2000 211 225
-
(2000)
Cell
, vol.103
, pp. 211-225
-
-
Schlessinger, J.1
-
33
-
-
0024361631
-
Activation of the purified protein tyrosine kinase domain of the epidermal growth factor receptor
-
P.B. Wedegaertner, and G.N. Gill Activation of the purified protein tyrosine kinase domain of the epidermal growth factor receptor J. Biol. Chem. 264 1989 11346 11353
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 11346-11353
-
-
Wedegaertner, P.B.1
Gill, G.N.2
-
34
-
-
10744230127
-
An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors
-
A.W. Burgess An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors Mol. Cell 12 2003 541 552
-
(2003)
Mol. Cell
, vol.12
, pp. 541-552
-
-
Burgess, A.W.1
-
35
-
-
2442647912
-
Two motifs within a transmembrane domain, one for homodimerization and the other for heterodimerization
-
D. Gerber Two motifs within a transmembrane domain, one for homodimerization and the other for heterodimerization J. Biol. Chem. 279 2004 21177 21182
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 21177-21182
-
-
Gerber, D.1
-
36
-
-
0035979763
-
Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain
-
T. Moriki Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain J. Mol. Biol. 311 2001 1011 1026
-
(2001)
J. Mol. Biol.
, vol.311
, pp. 1011-1026
-
-
Moriki, T.1
-
37
-
-
0032574959
-
Solution and solid state conformation of the human EGF receptor transmembrane region
-
A.C. Rigby Solution and solid state conformation of the human EGF receptor transmembrane region Biochim. Biophys. Acta 1371 1998 241 253
-
(1998)
Biochim. Biophys. Acta
, vol.1371
, pp. 241-253
-
-
Rigby, A.C.1
-
38
-
-
0034730672
-
A transmembrane peptide from the human EGF receptor: Behaviour of the cytoplasmic juxtamembrane domain in lipid bilayers
-
S. Sharpe, and C.W. Grant A transmembrane peptide from the human EGF receptor: behaviour of the cytoplasmic juxtamembrane domain in lipid bilayers Biochim. Biophys. Acta 1468 2000 262 272
-
(2000)
Biochim. Biophys. Acta
, vol.1468
, pp. 262-272
-
-
Sharpe, S.1
Grant, C.W.2
-
39
-
-
85047682496
-
Receptor dimerization in GH and erythropoietin action-it takes two to tango, but how?
-
S.J. Frank Receptor dimerization in GH and erythropoietin action-it takes two to tango, but how? Endocrinology 143 2002 2 10
-
(2002)
Endocrinology
, vol.143
, pp. 2-10
-
-
Frank, S.J.1
-
40
-
-
0033548048
-
Erythropoietin receptor activation by a ligand-induced conformation change
-
I. Remy Erythropoietin receptor activation by a ligand-induced conformation change Science 283 1999 990 993
-
(1999)
Science
, vol.283
, pp. 990-993
-
-
Remy, I.1
-
41
-
-
4043105621
-
The activity of the plexin-A1 receptor is regulated by Rac
-
L.J. Turner The activity of the plexin-A1 receptor is regulated by Rac J. Biol. Chem. 279 2004 33199 33205
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 33199-33205
-
-
Turner, L.J.1
-
42
-
-
1842505060
-
A two-state allosteric model for autoinhibition rationalizes WASP signal integration and targeting
-
M. Buck A two-state allosteric model for autoinhibition rationalizes WASP signal integration and targeting J. Mol. Biol. 338 2004 271 285
-
(2004)
J. Mol. Biol.
, vol.338
, pp. 271-285
-
-
Buck, M.1
-
43
-
-
0242384770
-
Activation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50)
-
W.B. Sneddon Activation-independent parathyroid hormone receptor internalization is regulated by NHERF1 (EBP50) J. Biol. Chem. 278 2003 43787 43796
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 43787-43796
-
-
Sneddon, W.B.1
-
44
-
-
0037031906
-
Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling
-
J. Takagi Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling Cell 110 2002 599 611
-
(2002)
Cell
, vol.110
, pp. 599-611
-
-
Takagi, J.1
-
45
-
-
0029966310
-
Breaking the integrin hinge. A defined structural constraint regulates integrin signaling
-
P.E. Hughes Breaking the integrin hinge. A defined structural constraint regulates integrin signaling J. Biol. Chem. 271 1996 6571 6574
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 6571-6574
-
-
Hughes, P.E.1
-
46
-
-
0037031551
-
A structural mechanism of integrin alpha(IIb)beta(3) "inside- out" activation as regulated by its cytoplasmic face
-
O. Vinogradova A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face Cell 110 2002 587 597
-
(2002)
Cell
, vol.110
, pp. 587-597
-
-
Vinogradova, O.1
-
47
-
-
1642529548
-
Membrane-mediated structural transitions at the cytoplasmic face during integrin activation
-
O. Vinogradova Membrane-mediated structural transitions at the cytoplasmic face during integrin activation Proc. Natl. Acad. Sci. U. S. A. 101 2004 4094 4099
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 4094-4099
-
-
Vinogradova, O.1
-
48
-
-
0033615646
-
Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects
-
Z. Zhou Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects J. Biol. Chem. 274 1999 31123 31126
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 31123-31126
-
-
Zhou, Z.1
-
49
-
-
0033521139
-
Misfolding of mutant aquaporin-2 water channels in nephrogenic diabetes insipidus
-
B.K. Tamarappoo Misfolding of mutant aquaporin-2 water channels in nephrogenic diabetes insipidus J. Biol. Chem. 274 1999 34825 34831
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34825-34831
-
-
Tamarappoo, B.K.1
-
50
-
-
0035066332
-
Alzheimer's disease: Genes, proteins, and therapy
-
D.J. Selkoe Alzheimer's disease: genes, proteins, and therapy Physiol. Rev. 81 2001 741 766
-
(2001)
Physiol. Rev.
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
51
-
-
0000496772
-
Vibrational dynamics of folded proteins: Significance of slow and fast motions in relation to function and stability
-
I. Bahar Vibrational dynamics of folded proteins: significance of slow and fast motions in relation to function and stability Phys. Rev. Lett. 80 1998 2733 2736
-
(1998)
Phys. Rev. Lett.
, vol.80
, pp. 2733-2736
-
-
Bahar, I.1
-
52
-
-
0346492917
-
Folding core predictions from network models of proteins
-
A.J. Rader, and I. Bahar Folding core predictions from network models of proteins Polymer 45 2004 659 668
-
(2004)
Polymer
, vol.45
, pp. 659-668
-
-
Rader, A.J.1
Bahar, I.2
-
53
-
-
0031672563
-
Identification of kinetically hot residues in proteins
-
M.C. Demirel Identification of kinetically hot residues in proteins Protein Sci. 7 12 1998 2522 2532
-
(1998)
Protein Sci.
, vol.7
, Issue.12
, pp. 2522-2532
-
-
Demirel, M.C.1
-
54
-
-
0035427398
-
Protein flexibility predictions using graph theory
-
D.J. Jacobs Protein flexibility predictions using graph theory Proteins 44 2001 150 165
-
(2001)
Proteins
, vol.44
, pp. 150-165
-
-
Jacobs, D.J.1
-
56
-
-
0036888379
-
Identifying protein folding cores from the evolution of flexible regions during unfolding
-
B.M. Hespenheide Identifying protein folding cores from the evolution of flexible regions during unfolding J. Mol. Graph. Model 21 2002 195 207
-
(2002)
J. Mol. Graph. Model
, vol.21
, pp. 195-207
-
-
Hespenheide, B.M.1
|