메뉴 건너뛰기




Volumn 116, Issue 1, 1997, Pages 61-69

Effects of dehydroepiandrosterone and calorie restriction on the Bcl-2/ Bax-mediated apoptotic pathway in p53-deficient mice

Author keywords

Apoptosis; Bax; Bcl 2; DHEA; Knockout mice; p53

Indexed keywords

CYCLINE; MESSENGER RNA; PRASTERONE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53;

EID: 0030959041     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(97)00175-4     Document Type: Article
Times cited : (31)

References (22)
  • 1
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr, J.F.R., Wyllie, A.H. and Currie, A.R. (1972) Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics, Br. J. Cancer, 26, 239-257.
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.R.1    Wyllie, A.H.2    Currie, A.R.3
  • 2
    • 0028240320 scopus 로고
    • Pathogenesis of cancer in view of mutually opposing apoptotic and anti-apoptotic growth signals
    • Mikulski, S.M. (1994) Pathogenesis of cancer in view of mutually opposing apoptotic and anti-apoptotic growth signals (review), Int. J. Oncol., 4, 1257-1263.
    • (1994) Int. J. Oncol. , vol.4 , pp. 1257-1263
    • Mikulski, S.M.1
  • 3
    • 0027255942 scopus 로고
    • Apoptosis and disease
    • Carson, D.A. and Ribeiro, J.M. (1993) Apoptosis and disease, Lancet, 341, 1251-1254.
    • (1993) Lancet , vol.341 , pp. 1251-1254
    • Carson, D.A.1    Ribeiro, J.M.2
  • 4
    • 0028675374 scopus 로고
    • Thymocyte and T cell apoptosis: Is all death created equal?
    • Ashwell, J.D. and King, L.B. (1995) Thymocyte and T cell apoptosis: is all death created equal?, Thymus, 23, 209-230.
    • (1995) Thymus , vol.23 , pp. 209-230
    • Ashwell, J.D.1    King, L.B.2
  • 6
    • 0025876591 scopus 로고
    • The p53 tumour suppressor gene
    • Levine, A.J., Momand, J. and Finlay, C.A. (1991) The p53 tumour suppressor gene, Nature, 351, 453-456.
    • (1991) Nature , vol.351 , pp. 453-456
    • Levine, A.J.1    Momand, J.2    Finlay, C.A.3
  • 7
    • 0028899283 scopus 로고
    • Biochemical properties and biological effects of p53
    • Haffner, R. and Oren, M. (1995) Biochemical properties and biological effects of p53, Curr. Opin. Genet.Dev., 5, 84-90.
    • (1995) Curr. Opin. Genet.Dev. , vol.5 , pp. 84-90
    • Haffner, R.1    Oren, M.2
  • 8
    • 0028568427 scopus 로고
    • The role of the p53 and Rb-1 genes in cancer, development and apoptosis
    • Hooper, M.L. (1994) The role of the p53 and Rb-1 genes in cancer, development and apoptosis, J. Cell Science, 18 (Suppl.), 13-17.
    • (1994) J. Cell Science , vol.18 , Issue.SUPPL. , pp. 13-17
    • Hooper, M.L.1
  • 10
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed, J.C. (1994) Bcl-2 and the regulation of programmed cell death, J. Cell. Biol., 124, 1-6.
    • (1994) J. Cell. Biol. , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 11
    • 0022971142 scopus 로고
    • Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/ immunoglobulin transcript resulting from the t(14;18) translocation
    • Cleary, M.L., Smith, S.D. and Sklar, J. (1986) Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/ immunoglobulin transcript resulting from the t(14;18) translocation, Cell, 47, 19-28.
    • (1986) Cell , vol.47 , pp. 19-28
    • Cleary, M.L.1    Smith, S.D.2    Sklar, J.3
  • 12
    • 0028072523 scopus 로고
    • DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanism inhibited by Bcl-2
    • Strasser, A., Harris, A.W., Jacks, T. and Cory, S. (1994) DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanism inhibited by Bcl-2, Cell, 79, 329-339.
    • (1994) Cell , vol.79 , pp. 329-339
    • Strasser, A.1    Harris, A.W.2    Jacks, T.3    Cory, S.4
  • 13
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai, Z.N., Milliman, C.L. and Korsmeyer, S.J. (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death, Cell, 74, 609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 15
    • 0029007175 scopus 로고
    • Effects of estrogen on apoptotic pathways in human breast cancer cell line MCF-7
    • Wang, T.T.Y. and Phang, J.M. (1995) Effects of estrogen on apoptotic pathways in human breast cancer cell line MCF-7, Cancer Res., 55, 2487-2489.
    • (1995) Cancer Res. , vol.55 , pp. 2487-2489
    • Wang, T.T.Y.1    Phang, J.M.2
  • 16
    • 0027199233 scopus 로고
    • Expression of the Bcl-2 protein in murine and human thymocytes and in peripheral T lymphocytes
    • Veis, D.J., Sentman, C.L., Bach, E.A. and Korsmeyer, S.J. (1993) Expression of the Bcl-2 protein in murine and human thymocytes and in peripheral T lymphocytes, J. Immunol., 151, 2546-2554.
    • (1993) J. Immunol. , vol.151 , pp. 2546-2554
    • Veis, D.J.1    Sentman, C.L.2    Bach, E.A.3    Korsmeyer, S.J.4
  • 17
    • 0027427492 scopus 로고
    • Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
    • Veis, D.J., Sorenson, C.M., Shutter, J.R. and Korsmeyer, S.J. (1993) Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair, Cell, 75, 229-240.
    • (1993) Cell , vol.75 , pp. 229-240
    • Veis, D.J.1    Sorenson, C.M.2    Shutter, J.R.3    Korsmeyer, S.J.4
  • 19
    • 0028237041 scopus 로고
    • Calorie restriction delays spontaneous tumorigenesis in p53-knockout transgenic mice
    • Hursting, S.D., Perkins, S.N. and Phang, J.M. (1994) Calorie restriction delays spontaneous tumorigenesis in p53-knockout transgenic mice, Proc. Natl. Acad. Sci., 91, 7036-7040.
    • (1994) Proc. Natl. Acad. Sci. , vol.91 , pp. 7036-7040
    • Hursting, S.D.1    Perkins, S.N.2    Phang, J.M.3
  • 21
    • 0029126002 scopus 로고
    • Chemoprevention of spontaneous tumorigenesis in p53-knockout mice
    • Hursting, S.D., Perkins, S.N., Haines, D.C., Ward, J.M. and Phang, J.M. (1995) Chemoprevention of spontaneous tumorigenesis in p53-knockout mice, Cancer Res., 55, 3949-3953.
    • (1995) Cancer Res. , vol.55 , pp. 3949-3953
    • Hursting, S.D.1    Perkins, S.N.2    Haines, D.C.3    Ward, J.M.4    Phang, J.M.5
  • 22
    • 0025269544 scopus 로고
    • Mechanism of chemoprevention by dietary dehydroepiandrosterone
    • Risdon, G., Cope, J. and Bennett, M. (1990) Mechanism of chemoprevention by dietary dehydroepiandrosterone, Am. J. Pathol., 136, 759-769.
    • (1990) Am. J. Pathol. , vol.136 , pp. 759-769
    • Risdon, G.1    Cope, J.2    Bennett, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.